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- Developmental systems (3)
- Epigenetics (3)
- Behavioral epigenetics (1)
- Behavioral genetics (1)
- Biological inheritance (1)
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- Character virtues (1)
- Development (1)
- Development and evolution (1)
- Developmental dynamics (1)
- Epigenetic inheritance (1)
- Evolutionary theory (1)
- GWAS (1)
- Gene-environment interactions (1)
- Genetic determinism (1)
- Nature-nurture (1)
- Nature-nurture concept (1)
- Polygenic scores (1)
- Relational developmental systems (1)
Articles 1 - 4 of 4
Full-Text Articles in Other Genetics and Genomics
Epigenetics And Character Virtue Development, David S. Moore
Epigenetics And Character Virtue Development, David S. Moore
Pitzer Faculty Publications and Research
Current understandings of epigenetics offer some insights into the developmental origins of character virtues. Research on epigenetics has demonstrated that phenotypes depend on both genomic and non-genomic information for their development, and such is true for the development of character virtues as well. This conclusion offers significant support for the Developmental Systems perspective. Although researchers have not yet studied the role of molecular epigenetic factors in the development of character, the field of behavioral epigenetics has revealed how such factors contribute to psychological and other behavioral phenotypes in general. In particular, behavioral epigenetics research can highlight the plasticity of human …
Polygenic Scores Ignore Development And Epigenetics, Dramatically Reducing Their Value, David S. Moore
Polygenic Scores Ignore Development And Epigenetics, Dramatically Reducing Their Value, David S. Moore
Pitzer Faculty Publications and Research
Polygenic scores cannot elucidate the mechanisms that produce behavioral phenotypes (including “intelligence”). Therefore, they are unlikely to yield helpful interventions. Moreover, they are poor predictors of individuals’ developmental outcomes. Burt’s critique is well-supported by the details of molecular biology. Specifically, experiences affect epigenetic factors that influence phenotypes via how the genome functions, a fact that lends support to Burt’s conclusions.
Molecular And Systemic Epigenetic Inheritance: Integrating Development, Genetics, And Evolution, Robert Lickliter, David S. Moore
Molecular And Systemic Epigenetic Inheritance: Integrating Development, Genetics, And Evolution, Robert Lickliter, David S. Moore
Pitzer Faculty Publications and Research
Currently, a central problem for theoretical biology is the integration of development with genetics and evolutionary theory. Through the late 20th century, biologists held that animals resemble their ancestors strictly because of the transgenerational transmission of DNA. This view effectively wrote development out of evolutionary biology. However, many molecular and developmental biologists now understand that phenotypes—anatomical, physiological, and behavioral traits—are not determined by genes (i.e., DNA segments) alone; instead, they emerge epigenetically from developmental processes involving co-acting genetic factors, environmental factors, molecular epigenetic factors, and other non-genetic factors within organisms’ bodies. This insight forces a rethinking of biological inheritance. …
The Potential Of Epigenetics Research To Transform Conceptions Of Phenotype Development, David S. Moore
The Potential Of Epigenetics Research To Transform Conceptions Of Phenotype Development, David S. Moore
Pitzer Faculty Publications and Research
Epigenetics remains an exciting subdiscipline of biology, generating discoveries and insights about development. Because epigenetic phenomena can draw attention to the dynamic, interactional, and probabilistic nature of phenotype development, epigenetics research could hasten the demise of both nature-nurture debates and reductionist, genetically determinist perspectives on phenotype development. However, new data alone will not inevitably transform conceptualizations of phenotype origins, because it remains possible to assimilate epigenetic phenomena into traditional conceptual frameworks; epigenetic discoveries could even strengthen biologically determinist conclusions if traditional conceptualizations are retained. Although epigenetics will not force conceptual transformation, epigenetics research encourages the dismissal of the nature-nurture dichotomy …