Open Access. Powered by Scholars. Published by Universities.®
- Discipline
-
- Medicine and Health Sciences (26)
- Medical Sciences (21)
- Medical Genetics (20)
- Medical Specialties (15)
- Genomics (9)
-
- Biomedical Informatics (8)
- Bioinformatics (7)
- Diseases (7)
- Oncology (5)
- Biological Phenomena, Cell Phenomena, and Immunity (4)
- Cardiovascular Diseases (4)
- Cell and Developmental Biology (4)
- Genetic Processes (4)
- Medical Molecular Biology (4)
- Public Health (4)
- Biochemistry, Biophysics, and Structural Biology (3)
- Epidemiology (3)
- Genetic Phenomena (3)
- Molecular Genetics (3)
- Biology (2)
- Cardiology (2)
- Social and Behavioral Sciences (2)
- Anatomy (1)
- Animal Sciences (1)
- Biochemistry (1)
- Biomedical Engineering and Bioengineering (1)
- Biostatistics (1)
- Institution
- Publication Year
- Publication
-
- Faculty, Staff and Student Publications (12)
- Faculty, Staff and Students Publications (7)
- Dartmouth Scholarship (6)
- Epidemiology and Environmental Health Faculty Publications (2)
- Biology, Chemistry, and Environmental Sciences Faculty Articles and Research (1)
-
- CALS Publications (1)
- Department of Biomedical and Translational Sciences Faculty Publications (1)
- Department of Pharmacology, Physiology, and Cancer Biology Faculty Papers (1)
- Electrical & Computer Engineering Faculty Publications (1)
- Rowan-Virtua School of Osteopathic Medicine Departmental Research (1)
- Wills Eye Hospital Papers (1)
Articles 31 - 34 of 34
Full-Text Articles in Genetics
Parentage Analysis With Genetic Markers In Natural Populations I The Expected Proportion Of Offspring With Unambiguous Paternity, R Chakraborty, T R Meagher, P E Smouse
Parentage Analysis With Genetic Markers In Natural Populations I The Expected Proportion Of Offspring With Unambiguous Paternity, R Chakraborty, T R Meagher, P E Smouse
Faculty, Staff and Student Publications
Recent studies indicate that polymorphic genetic markers are potentially helpful in resolving genealogical relationships among individuals in a natural population. Genetic data provide opportunities for paternity exclusion when genotypic incompatibilities are observed among individuals, and the present investigation examines the resolving power of genetic markers in unambiguous positive determination of paternity. Under the assumption that the mother for each offspring in a population is unambiguously known, an analytical expression for the fraction of males excluded from paternity is derived for the case where males and females may be derived from two different gene pools. This theoretical formulation can also be …
Genetics And Epidemiology Of Gallbladder Disease In New World Native Peoples, K M Weiss, R E Ferrell, C L Hanis, P N Styne
Genetics And Epidemiology Of Gallbladder Disease In New World Native Peoples, K M Weiss, R E Ferrell, C L Hanis, P N Styne
Faculty, Staff and Student Publications
Native peoples of the New World, including Amerindians and admixed Latin Americans such as Mexican-Americans, are highly susceptible to diseases of the gallbladder. These include cholesterol cholelithiasis (gallstones) and its complications, as well as cancer of the gallbladder. Although there is clearly some necessary dietary or other environmental risk factor involved, the pattern of disease prevalence is geographically associated with the distribution of genes of aboriginal Amerindian origin, and levels of risk generally correspond to the degree of Amerindian admixture. This pattern differs from that generally associated with Westernization, which suggests a gene-environment interaction, and that within an admixed population …
Genetically Controlled Variation Of “Acid” Beta-Galactosidase Detected In Rattus Norvegicus By Isoelectric Focusing, T C Douglas, K A Kimmel, P E Dawson
Genetically Controlled Variation Of “Acid” Beta-Galactosidase Detected In Rattus Norvegicus By Isoelectric Focusing, T C Douglas, K A Kimmel, P E Dawson
Faculty, Staff and Student Publications
Two genetically variant forms of rat "acid" beta-galactosidase were found to differ in isoelectric point and pH dependence, but not in thermostability or sensitivity to inhibition by p-mercuribenzoate (PMB). The results of two backcrosses and an intercross indicated that the isoelectric focusing phenotypes are controlled by two codominant alleles at a single autosomal locus, for which we propose the name Glb-1. No significant linkage between Glb-1 and albino (LG I), brown (LG II), or hooded (LG VI) was observed. Strain-specific differences in total levels of kidney beta-galactosidase were detected, but it is not yet known whether the variation is controlled …
Three Linked Enzyme Loci In Fishes: Implications In The Evolution Of Vertebrate Chromosomes, D C Morizot, D A Wright, M J Siciliano
Three Linked Enzyme Loci In Fishes: Implications In The Evolution Of Vertebrate Chromosomes, D C Morizot, D A Wright, M J Siciliano
Faculty, Staff and Student Publications
A three-point linkage group comprised of loci coding for adenosine deaminase (ADA), glucose-6-phosphate dehydrogenase (G6PDH), and 6-phospho-gluconate dehydrogenase (6PGD) is described in fish of the genus Xiphophorus (Poeciliidae). The alleles at loci in this group were shown to assort independently from the alleles at three other loci--isocitrate dehydrogenase 1 and 2, and glyceraldehyde-3-phosphate dehydrogenase 1. Alleles at the latter three loci also assort independently from each other. Data were obtained by observing the segregation of electrophoretically variant alleles in reciprocal backcross hybrids derived from crosses between either X. helleri guentheri or X. h. strigatus and X. maculatus. The linkage component …