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Full-Text Articles in Food Biotechnology
Biosafety: Evaluation And Regulation Of Genetically Modified (Gm) Crops In The United States, Richard E. Goodman
Biosafety: Evaluation And Regulation Of Genetically Modified (Gm) Crops In The United States, Richard E. Goodman
Department of Food Science and Technology: Faculty Publications
This review of the safety assessment of genetically modified (GM) crops is focused primarily on the process and progress in the United States (US). It reviews the development of the safety evaluation process from the Asilomar conference in 1975 considering issues relevant to recombinant DNA technology, to discussions between the US government, academic and industrial scientists between 1984 and 1994 when the first GM crops were being field tested and evaluated commercial release for food and feed production. International guidelines were also reviewed for consistency with the US system. The overall process includes consideration of information relating to history of …
生物安全:美国转基因作物的评价与管理, Richard E. Goodman
生物安全:美国转基因作物的评价与管理, Richard E. Goodman
Department of Food Science and Technology: Faculty Publications
本篇综述侧重于介绍美国本土的转基因作物安全评价的过程和进展。回顾了安全评价程序的建 立过程,从1975年阿西洛马(Asilomar)会议上关于重组DNA技术的问题,自1984-1994年间第一例转基因作 物进行田间试验到评估作为食物和饲料商业化生产时,美国政府、学术界和产业界科学家之间的讨论。此外,一 同回顾国际上的指南与美国的系统。整体过程还要考虑人类接触基因来源和表达蛋白是否有安全的或不安全 的历史。食用蛋白安全性首要考虑因素为某些消费者是否对其过敏或者拥有转基因编码蛋白的IgE抗体,或者 转基因食品会诱发乳糜泻,同时考虑表达蛋白的潜在毒性效果和对人或动物营养的影响。在美国,该过程与国 际食品法典委员会的建议是一致的,它是基于科学的并应用合理的假设。迄今为止,没有证据证明在美国获得 批准的转基因作物危害人或动物的健康。评价要考虑遗传和环境上的变化对植物新品种产物的影响,并坚持转 基因植物食品和非转基因相似物种同样安全的评价原则。
Gmos: Are They A Regulatory Or Food Safety Issue?, Richard E. Goodman
Gmos: Are They A Regulatory Or Food Safety Issue?, Richard E. Goodman
Department of Food Science and Technology: Faculty Publications
Most of the genetic diversity that has improved agricultural production throughout the history of farming was developed through natural mutations and selective breeding. However, since the early 1900s plant scientists have used chemical and radiation mutagenesis to increase genetic diversity (18). We know that the majority of mutations are harmful, and plant breeders work hard to select only those that are beneficial. This process has helped feed a growing human population, which is estimated to have been 300 million 2,000 years ago and is now more than 7 billion. However, methods used in the past to improve agricultural production are …
Evaluation Of Endogenous Allergens For The Safety Evaluation Of Genetically Engineered Food Crops: Review Of Potential Risks, Test Methods, Examples And Relevance, Richard E. Goodman, Rakhi Panda, Harsha Ariyarathna
Evaluation Of Endogenous Allergens For The Safety Evaluation Of Genetically Engineered Food Crops: Review Of Potential Risks, Test Methods, Examples And Relevance, Richard E. Goodman, Rakhi Panda, Harsha Ariyarathna
Department of Food Science and Technology: Faculty Publications
The safety of food produced from genetically engineered (GE) crops is assessed for potential risks of food allergy on the basis of an international consensus guideline outlined by the Codex Alimentarius Commission (2003). The assessment focuses on evaluation of the potential allergenicity of the newly expressed protein(s) as the primary potential risk using a process that markedly limits risks to allergic consumers. However, Codex also recommended evaluating a second concern, potential increases in endogenous allergens of commonly allergenic food crops that might occur due to insertion of the gene. Unfortunately, potential risks and natural variation of endogenous allergens in non-GE …