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2021

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Articles 31 - 60 of 858

Full-Text Articles in Food Science

Application And Progress Of Molecularly Imprinted Sensors In Mycotoxins Detection, Ding Tong-Ying, Yuan Hang Dec 2021

Application And Progress Of Molecularly Imprinted Sensors In Mycotoxins Detection, Ding Tong-Ying, Yuan Hang

Food and Machinery

This article reviews the principle and classification of molecularly imprinted sensors （MIS）, focuses on the research results and application status of MIS in mycotoxin detection, and provides reference for better application of MIS to its future development direction.

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Application Progress Of Chromatographic Technology In The Separation And Purification Of Flavonoids, Yang Fa-Rong, Jing Lian-Peng, Gu Li-Li, Shang Guan-Lan, Li Rui-Dong Dec 2021

Application Progress Of Chromatographic Technology In The Separation And Purification Of Flavonoids, Yang Fa-Rong, Jing Lian-Peng, Gu Li-Li, Shang Guan-Lan, Li Rui-Dong

Food and Machinery

In this review, the application of chromatographic techniques in the separation and purification of flavonoids was summarized. The usage of column chromatography, pre-high-performance liquid chromatography, thin-layer chromatography, supercritical fluid chromatography, high-speed countercurrent chromatography and a combination of multiple chromatography methods were also reviewed. The development direction of preparative liquid chromatography columns, the optimization of solvent system for high-speed countercurrent chromatography, and the use of multi-dimensional chromatography systems were prospected.

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Research On Functional Activities Of Organic Acids In Edible Plant Ferment, Huang Ying, Ren Ting-Yuan, Wan Hong-Qiong, Xie Jiao Dec 2021

Research On Functional Activities Of Organic Acids In Edible Plant Ferment, Huang Ying, Ren Ting-Yuan, Wan Hong-Qiong, Xie Jiao

Food and Machinery

The composition of organic acids in enzyme products and their dynamic changes during fermentation process were reviewed, and the function activities of organic acids in enzyme products beneficial to human health, such as antioxidant, adjustment of intestinal flora, enhancement of satiety, anti-tumor, etc were summarized. Moreover, the evaluation system and mechanism of organic acids in edible enzymes were proposed to be further studied.

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Research Progress On The Application Of Blending Automation In The Production Of Baijiu, Han Qiang, Liu Xin, Zhou Yong-Shuai, Tuo Xian-Guo, Zhang Liang Dec 2021

Research Progress On The Application Of Blending Automation In The Production Of Baijiu, Han Qiang, Liu Xin, Zhou Yong-Shuai, Tuo Xian-Guo, Zhang Liang

Food and Machinery

The article briefly describes the blending process and its importance in the production process of Baijiu, and elaborates on the current status of the application of blending recipes, automation control, computers and other technologies in the blending of Baijiu; addresses the current difficulties in blending research and implementation, summarises the shortcomings at this stage from both the researcher's and the company's perspectives, and provides an outlook on future directions for improvement.

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The Development Experience And Enlightenment Of American Nutrition Facts Panel, Huang Ze-Ying, Huang Bei-Xun Dec 2021

The Development Experience And Enlightenment Of American Nutrition Facts Panel, Huang Ze-Ying, Huang Bei-Xun

Food and Machinery

Our study collected material and information of the nutrition facts panel from the official website of Food and Drug Administration in America and authoritative literatures, and elaborated the evolution, publicity and education of the nutrition facts panel, implementation effect and deficiency, American front of package labels related to the nutrition facts panel, and comparison with the nutrition facts table in China. Moreover, the successful experience and enlightenments were summarized, and the advice for improving the nutrition facts table in China was also proposed.

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Analysis Of Volatile Aroma Components Of Ampelopsis Grossedentata Tea With Different Processing Technology Based On Gc-Ms Combined With Roav, Zhang Jin-Cheng, Yu Ji, Ma Cheng-Jin, Yao Mao-Jun, Wu Zhu-Qing Dec 2021

Analysis Of Volatile Aroma Components Of Ampelopsis Grossedentata Tea With Different Processing Technology Based On Gc-Ms Combined With Roav, Zhang Jin-Cheng, Yu Ji, Ma Cheng-Jin, Yao Mao-Jun, Wu Zhu-Qing

Food and Machinery

Objective: This study aimed to explore the influence of processing technology on characteristic aroma components of Ampelopsis Grossedentata tea. Methods: Four different samples of A. Grossedentata were prepared by traditional processing technology, black tea processing technology, green tea processing technology and dark tea processing technology, and the key flavor compounds of different samples were analyzed by headspace solid-phase microextraction and gas chromatography-mass spectrometry combined with relative odor activity （ROAV）, taking the naturally dried A. Grossedentata leaves as control. Results: A total of 37 volatile flavor compounds were detected from 4 kinds of A. Grossedentata tea samples and control samples, among …

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Prediction Model Building For Finished Tobacco Quality Based On Miv-Bp Neural Network, Zhuo Ming, Wang Peng, Wang Kai-Kui Dec 2021

Prediction Model Building For Finished Tobacco Quality Based On Miv-Bp Neural Network, Zhuo Ming, Wang Peng, Wang Kai-Kui

Food and Machinery

Objective: The simulation and prediction model between the process of silk making and the quality of finished tobacco was established. Methods: The average influence value method was used to screen the process parameters in the process of making silk, and then a simulation model of the key process parameters of the silk and the quality of the final tobacco was constructed through the Back-Propagation neural network. Results: Comparing the simulated data with the measured data, the average relative error of the simulated prediction of the filling value was 3.16%; the average relative error of the simulated prediction of the whole …

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Reconstruction Of Branded Leisure Food Supply Chain Under The Background Of Business Model Innovation, Li Xia, Lu Yue, Li Feng-Ting, Wang Pei-Pei Dec 2021

Reconstruction Of Branded Leisure Food Supply Chain Under The Background Of Business Model Innovation, Li Xia, Lu Yue, Li Feng-Ting, Wang Pei-Pei

Food and Machinery

The paper proposed that branded leisure food companies should keep up with the pace of business model innovation, reduce production costs, expand product sales channels and improve logistics efficiency by analyzing the problems of traditional Branded Leisure Food Supply Chain（BLFSC） under the E-commerce model. Additionally, it is pointed out that branded leisure food companies urgently need restructure and improve the overall circulation efficiency of BLFSC under the background of innovative business models.

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Application Of A Bacteriophage–Sanitizer Combination In Post-Harvest Control Of E. Coli O157:H7 Contamination On Spinach Leaves In The Presence Or Absence Of A High Organic Load Produce Wash, Badrinath Vengarai Jagannathan, Steven Kitchens, Stuart Price, Melissa Morgan, Paul Priyesh Vijayakumar Dec 2021

Application Of A Bacteriophage–Sanitizer Combination In Post-Harvest Control Of E. Coli O157:H7 Contamination On Spinach Leaves In The Presence Or Absence Of A High Organic Load Produce Wash, Badrinath Vengarai Jagannathan, Steven Kitchens, Stuart Price, Melissa Morgan, Paul Priyesh Vijayakumar

Animal and Food Sciences Faculty Publications

Foodborne illness due to the consumption of contaminated products continues to be a serious public health issue. Bacteriophages might provide a natural and effective way to control and reduce the pathogenic bacterial population on food products. Researchers have conducted various experiments to prove their effectiveness against different pathogens and their ability to act as a natural intervention to control pathogen populations, especially in the food industry. In this study, a cocktail of bacteriophages (phages) was added to wash water in the presence of a high organic load along with commercially used sanitizers (chlorine or Sanidate 5.0) to study the efficacy …

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Acknowledgment Of Reviewers Dec 2021

Acknowledgment Of Reviewers

Journal of Food and Drug Analysis

No abstract provided.

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Molecular Cartography Of Residue Pesticides On Grape Surface In 3d By Ambient Ionization Tandem Mass Spectrometry, Hung Su, Tiao-Lai Huang, Cheng-Ting Chi, Yi-Tzu Cho, Chi-Wei Lee, Jingyueh Jeng, Jentaie Shiea Dec 2021

Molecular Cartography Of Residue Pesticides On Grape Surface In 3d By Ambient Ionization Tandem Mass Spectrometry, Hung Su, Tiao-Lai Huang, Cheng-Ting Chi, Yi-Tzu Cho, Chi-Wei Lee, Jingyueh Jeng, Jentaie Shiea

Journal of Food and Drug Analysis

Thermal desorption-electrospray ionization tandem mass spectrometry (TD-ESI/MS/MS) was used to characterize the residual pesticides that were collected from the surface of a grape with metallic sampling probes. Fungicides, insecticides, and miticides were detected, where results were validated by simple solvent extraction followed by gas chromatography tandem mass spectrometry and liquid chromatography tandem mass spectrometry analyses. To explore the distribution of pesticide residues on grape surfaces, 149 locations of a grape surface were collected and followed by TD-ESI/MS/MS analysis. The molecular cartography was then generated from analysis of residual pesticides on the grape surface in 3D.

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Variations In Bovine Milk Oligosaccharides After Calving Using P-Aminobenzoic Ethyl Ester Closed-Ring Labeling And Negative Ion Electrospray Lc/Ms/Ms, Han-Ju Chien, Yi-Chun Ma, Yi-Feng Zheng, Cheng-Yu Kuo, Wei-Chen Wang, Guor-Rong Her, Chien-Chen Lai Dec 2021

Variations In Bovine Milk Oligosaccharides After Calving Using P-Aminobenzoic Ethyl Ester Closed-Ring Labeling And Negative Ion Electrospray Lc/Ms/Ms, Han-Ju Chien, Yi-Chun Ma, Yi-Feng Zheng, Cheng-Yu Kuo, Wei-Chen Wang, Guor-Rong Her, Chien-Chen Lai

Journal of Food and Drug Analysis

A strategy was proposed to analyze bovine milk oligosaccharides using p-aminobenzoic ethyl ester (ABEE) closed-ring labeling and C18 capillary liquid chromatography negative ion electrospray tandem mass spectrometry. Linkage specific fragment ions were used to identify oligosaccharide isomers. By constructing the mass chromatograms using linkage specific fragment ions, isomers were differentiated based on m/z values as well as temporal separation provided by liquid chromatography. In addition to disialyllactose and the single isomer lacto-N-neohexaose, four pairs of linkage isomers including 3’/6’-sialyllactose (3’/6’-SL), 3’/6’-sialyllactosamine (3’/6’-SLN), 3’/6’-sialylgalactosyl-lactose (3’/6’-SGL), and lacto-N-tetraose/lacto-N-neotetraose (LNT/LNnT) in bovine milk were investigated. Variations of bovine milk oligosaccharides in a …

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Analysis Of Heterocyclic Aromatic Amines Using Selective Extraction By Magnetic Molecularly Imprinted Polymers Coupled With Liquid Chromatography – Mass Spectrometry, Shih-Ci Jhu, Jing-Ying Wang, Hsueh-Ting Wang, Sung-Fang Chen Dec 2021

Analysis Of Heterocyclic Aromatic Amines Using Selective Extraction By Magnetic Molecularly Imprinted Polymers Coupled With Liquid Chromatography – Mass Spectrometry, Shih-Ci Jhu, Jing-Ying Wang, Hsueh-Ting Wang, Sung-Fang Chen

Journal of Food and Drug Analysis

Heterocyclic aromatic amines (HCAs) are highly carcinogenic and mutagenic chemicals. This study reports on the development of magnetic molecularly imprinted polymers (MMIPs) for the purification and quantification of HCAs. A novel magnetic molecularly imprinted polymer was successfully prepared using a surface molecular imprinting method using functionalized Fe particles as the magnetic cores. 2-Amino-3-methylimidazo[4,5-f]quinoline (IQ) was used as a molecular template; methacrylic acid (MAA), ethylene glycol dimethyl acrylate (EGDMA), 2, 2′-Azobis (2-methylpropionitrile) were used as the functional monomer, crosslinker, and initiator, respectively. The use of the template/functional monomer/crosslinking agent at a ratio of 1:4:20 resulted in a product with better adsorption …

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The Impact Of The Rare Disease And Orphan Drug Act In Taiwan, Ning-Chun Hsiang, Weng-Foung Huang, Churn-Shiouh Gau, Teng-Wen Tsai, Lin-Chau Chang Dec 2021

The Impact Of The Rare Disease And Orphan Drug Act In Taiwan, Ning-Chun Hsiang, Weng-Foung Huang, Churn-Shiouh Gau, Teng-Wen Tsai, Lin-Chau Chang

Journal of Food and Drug Analysis

The Rare Disease and Orphan Drug Act (the Act) was enacted in 2000 in Taiwan for the facilitation of the research, development, and accessibility of orphan drugs and special nutritional foods; for the prevention and early diagnosis of rare diseases; and for providing intensive care for patients with rare diseases. The aim was to investigate the impact of the Act on the availability and use of orphan drugs in Taiwan in the hope of identifying the remaining challenges and possible solutions to assist future policy making, which may be applicable in other countries as well. The information and statistics for …

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Determination Of Quetiapine And Its Metabolites In Plasma By Field-Enhanced Sample Stacking, Tai-Ling Liu, Li-Shan Fang, Jing-Ru Liou, Jia-Shan Dai, Yen-Ling Chen Dec 2021

Determination Of Quetiapine And Its Metabolites In Plasma By Field-Enhanced Sample Stacking, Tai-Ling Liu, Li-Shan Fang, Jing-Ru Liou, Jia-Shan Dai, Yen-Ling Chen

Journal of Food and Drug Analysis

Quetiapine is an atypical antipsychotic drug that can be used to treat mental disorders, including schizophrenia, bipolar disorder and Alzheimer's disease. Quetiapine is mainly converted into the active metabolites of norquetiapine and 7-hydroxyquetiapine by the liver enzymes CYP3A4 and CYP2D6. In this study, liquid-liquid extraction (LLE) was used as a sample pretreatment method to eliminate interferences in plasma. tert-Butyl methyl ether was chosen as the extraction solvent. Field-enhanced sample injection (FESS), an online preconcentration technique, was used to analyze quetiapine and its metabolites norquetiapine and 7-hydroxyquetiapine in plasma. The optimal separation condition was 120 mM phosphate (pH 4.0) containing …

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Quantitative Analysis Of Fragrance Allergens In Various Matrixes Of Cosmetics By Liquid-Liquid Extraction And Gc-Ms, Chia-Hui Lu, Ming-Chih Fang, Yu-Zi Chen, Shou-Chieh Huang, Der-Yuan Wang Dec 2021

Quantitative Analysis Of Fragrance Allergens In Various Matrixes Of Cosmetics By Liquid-Liquid Extraction And Gc-Ms, Chia-Hui Lu, Ming-Chih Fang, Yu-Zi Chen, Shou-Chieh Huang, Der-Yuan Wang

Journal of Food and Drug Analysis

Fragrances are the most common chemicals in cosmetics to which people expose every day. However, the unwanted allergic reactions such as contact dermatitis caused by direct contact with fragrances may happen. In Directive 2003/15/EC of the EU, cosmetic product containing one or more of 26 fragrance allergens must be declared on the package label. In addition, commission regulation (EU) 2017/1410 amending Annexes II and III of cosmetic regulation 1223/2009 restricted fragrance chemical of methyl eugenol, and prohibited Lyral, atranol, chloroatranol to be used in cosmetic. In this study, an efficient and sensitive GC-MS method for 3 banned fragrances, 26 fragrance …

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Diagnostic Ions Guided 2d-Locating Strategy For Characterization Of Chemical Analogues In Complex Herbal Medicines Using Liquid Chromatography-Ion Mobility-Mass Spectrometry, Meng-Ning Li, Zi-Xuan Zhang, Hui-Ying Wang, Wen Gao, Ping Li, Hua Yang Dec 2021

Diagnostic Ions Guided 2d-Locating Strategy For Characterization Of Chemical Analogues In Complex Herbal Medicines Using Liquid Chromatography-Ion Mobility-Mass Spectrometry, Meng-Ning Li, Zi-Xuan Zhang, Hui-Ying Wang, Wen Gao, Ping Li, Hua Yang

Journal of Food and Drug Analysis

Rapid characterization of chemical analogues in potentially toxic complex matrix was essential for prevention of accidental poisoning. On the basis of the fragment ions possessed not only the same retention times (RT) but the same drift times (DT) on liquid chromatography-ion mobility-mass spectrometry (LC-IM-MS), an alternating frames (AF)-data independent acquisition (DIA) was utilized for simultaneous detection and rapid match of precursor/product ions with a fast switch of low/high collision energy (CE). A diagnostic ions guided 2D-locating strategy was developed for identification of chemical analogues in potentially toxic herbal medicines using LC-IM-MS. Firstly, the 2D-locations (RT, DT) of diagnostic ions were …

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Pharmacokinetics Of Panduratin A Following Oral Administration Of A Boesenbergia Pandurata Extract To Rats, Jihyun Won, Keumhan Noh, Jae-Kwan Hwang, Beom Soo Shin, Wonku Kang Dec 2021

Pharmacokinetics Of Panduratin A Following Oral Administration Of A Boesenbergia Pandurata Extract To Rats, Jihyun Won, Keumhan Noh, Jae-Kwan Hwang, Beom Soo Shin, Wonku Kang

Journal of Food and Drug Analysis

Boesenbergia pandurata and its major active ingredient, panduratin A (PAN), exhibit antibacterial, anti-oxidant, anti-inflammatory, and anti-obesity effects. We explored the time course of the plasma and tissue (in the major organs, gums and skin) concentrations of PAN after oral administration of a B. pandurata extract to rats. Model-dependent analysis was used to quantify the skin distribution of PAN after systemic exposure. The PAN level peaked at 1.12 ± 0.22 μg/mL after 3 h, and then biexponentially decayed with a terminal half-life of 9 h. The mean clearance (Cl/F) was 2.33 ± 0.68 L/h/kg. The PAN levels in organs were in …

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Identification Of Oxytocin Receptor Activating Chemical Components From Traditional Japanese Medicines, Yuko Maejima, Shoichiro Horita, Shoko Yokota, Tomoyuki Ono, Peter Proks, Hiromi Yoshida-Komiya, Yoichi Ueta, Katsuhiko Nishimori, Shingen Misaka, Kenju Shimomura Dec 2021

Identification Of Oxytocin Receptor Activating Chemical Components From Traditional Japanese Medicines, Yuko Maejima, Shoichiro Horita, Shoko Yokota, Tomoyuki Ono, Peter Proks, Hiromi Yoshida-Komiya, Yoichi Ueta, Katsuhiko Nishimori, Shingen Misaka, Kenju Shimomura

Journal of Food and Drug Analysis

Oxytocin (Oxt) is known to regulate social communication, stress and body weight. The activation of Oxt receptors (OTR) has clinical potential to abate stress disorders and metabolic syndrome. Kamikihito (KKT) is a traditional Japanese medicine used to treat psychological stress-related disorders. We investigated the effects of KKT, its ingredients and chemical components on Oxt neurons and OTR. C-Fos expression was examined after oral and peripheral administration of KKT in rats. Electrophysiological change of Oxt neurons and Oxt release upon application of KKT were measured in rat brain slice. The direct effect of KKT, its ingredients and its chemical components were …

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A Novel Nrf2/Are Inhibitor Gossypol Induces Cytotoxicity And Sensitizes Chemotherapy Responses In Chemo-Refractory Cancer Cells, Ya-Chu Tang, Hsin-Huei Chang, Huang-Hui Chen, Jau-Ying Yao, Yu-Tsen Chen, Yung-Jen Chuang, Jang-Yang Chang, Ching-Chuan Kuo Dec 2021

A Novel Nrf2/Are Inhibitor Gossypol Induces Cytotoxicity And Sensitizes Chemotherapy Responses In Chemo-Refractory Cancer Cells, Ya-Chu Tang, Hsin-Huei Chang, Huang-Hui Chen, Jau-Ying Yao, Yu-Tsen Chen, Yung-Jen Chuang, Jang-Yang Chang, Ching-Chuan Kuo

Journal of Food and Drug Analysis

NRF2/ARE signaling pathway is a principal regulator of cellular redox homoeostasis. The stress-induced transcription factor, NRF2, can shield cells from the oxidative damages via binding to the consensus antioxidant-responsive element (ARE) and driving several cyto-protective genes expression. Increasing evidence indicated that aberrant activation of NRF2 in malignant cells may support their survival through various pathways to detoxify chemotherapy drugs, attenuate drug-induced oxidative stress, or induce drug efflux, all of which are crucial in developing drug resistance. Accordingly, NRF2 is a potential drug target for improving the effectiveness of chemotherapy and to reverse drug resistance in cancer cells. A stable ARE-driven …

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Curcumin-Induced Antitumor Effects On Triple-Negative Breast Cancer Patient-Derived Xenograft Tumor Mice Through Inhibiting Salt-Induced Kinase-3 Protein, Tzu-Chun Cheng, John Oliver Sayseng, Shih-Hsin Tu, Ting-Ching Juan, Chia-Lang Fang, You-Cheng Liao, Cheng-Ying Chu, Hui-Wen Chang, Yun Yen, Li-Ching Chen, Yuan-Soon Ho Dec 2021

Curcumin-Induced Antitumor Effects On Triple-Negative Breast Cancer Patient-Derived Xenograft Tumor Mice Through Inhibiting Salt-Induced Kinase-3 Protein, Tzu-Chun Cheng, John Oliver Sayseng, Shih-Hsin Tu, Ting-Ching Juan, Chia-Lang Fang, You-Cheng Liao, Cheng-Ying Chu, Hui-Wen Chang, Yun Yen, Li-Ching Chen, Yuan-Soon Ho

Journal of Food and Drug Analysis

This study demonstrated for the first time that curcumin effectively inhibits the growth of triple-negative breast cancer (TNBC) tumors by inhibiting the expression of salt-induced kinase-3 (SIK3) protein in patient-derived xenografted tumor mice (TNBC-PDX). For TNBC patients, chemotherapy is the only option for postoperative adjuvant treatment. In this study, we detected the SIK3 mRNA expression in paired-breast cancer tissues by PCR analysis. The results revealed that SIK3 mRNA expression was significantly higher in tumor tissues when compared to the normal adjacent tissues (73.25 times, n=183). Thus, it is proposed for the first time that the antitumor effect induced by curcumin …

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Anti-Lymphangiogenic Diterpenes From The Bark Of Calocedrus Macrolepis Var. Formosana, Tzong-Huei Lee, Chin-Lin Hsieh, Ho-Cheng Wu, Shih-Wei Wang, Chen-Lin Yu, George Hsiao, Ming-Jen Cheng, Wen-Tsong Hsieh, Yueh-Hsiung Kuo Dec 2021

Anti-Lymphangiogenic Diterpenes From The Bark Of Calocedrus Macrolepis Var. Formosana, Tzong-Huei Lee, Chin-Lin Hsieh, Ho-Cheng Wu, Shih-Wei Wang, Chen-Lin Yu, George Hsiao, Ming-Jen Cheng, Wen-Tsong Hsieh, Yueh-Hsiung Kuo

Journal of Food and Drug Analysis

Eight new diterpenes, 6α,7β-dihydroxyferruginol (1), 6α,7α-dihydroxyferruginol (2), 6α-hydroxyhinokiol (3), 4α-hydroxy-7-oxo-18-norabieta-8,11,13-trien-4α-ol (4a), 15,16-dehydrosugiol (5), 7-methoxy-6,7-secoabieta-8,11,13-triene-6,12-diol (6), 7α-acetoxyabieta-8,12-diene-11,14-dione (7), 7α-butyloxyethyloxyabieta-8,12-diene-11,14-dione (8), along with four known compounds, 6,7-dehydroferruginol (9), 12-hydroxy-6,7-secoabieta-8,11,13-triene-6,7-dial (10), 7α-11-dihydroxy-12-methoxy-8,11,13-abietatriene (11), and 11,14-dihydroxy-8,11,13-abietatrien-7-one (12) were successfully isolated from the bark of Calocedrus macrolepis var. formosana. The structures of all isolates were elucidated by physical data (appearance, UV, IR, optical rotation) and spectroscopic data (1D, 2D NMR, and HREIMS). Compounds 9, 10, 11, and 12 showed promising growth-inhibitory effect on human lymphatic endothelial cells (LECs). Among these compounds, compound 10 exerted the most potent anti-lymphangiogenesis property by suppressing cell growth and …

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Medicarpin Isolated From Radix Hedysari Ameliorates Brain Injury In A Murine Model Of Cerebral Ischemia, Chang-Ming Chern, Chung-Kuang Lu, Kuo-Tong Liou, Yea-Hwey Wang, Keng-Chang Tsai, Chia-Lin Chang, Chia-Che Chang, Yuh-Chiang Shen Dec 2021

Medicarpin Isolated From Radix Hedysari Ameliorates Brain Injury In A Murine Model Of Cerebral Ischemia, Chang-Ming Chern, Chung-Kuang Lu, Kuo-Tong Liou, Yea-Hwey Wang, Keng-Chang Tsai, Chia-Lin Chang, Chia-Che Chang, Yuh-Chiang Shen

Journal of Food and Drug Analysis

The development of effective post-stroke therapy is highly demanded. Medicarpin is a key active component of a famous Chinese herbal prescription used for post-stroke treatment in Taiwan; however, little is known about its biological effects and mechanisms of action. Herein, we implemented a murine model of cerebral ischemic/reperfusional injury-related stroke to elucidate medicarpin’s neuroprotective effect. In male ICR mice 24 h after stroke induction, treatment with medicarpin (0.5 and 1.0 mg/kg, i.v.) markedly enhanced the survival rates, improved moving distance and walking area coverage, reduced brain infarction, and preserved the blood-brain barrier, supporting medicarpin’s protective effect on stroke-induced injury. Immunohistochemistry …

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In-Silico Efficacy Of Potential Phytomolecules From Ayurvedic Herbs As An Adjuvant Therapy In Management Of Covid-19, Bhanu Kumar, Ankita Misra, Satyendra Pratap Singh, Yogeshwar Vikram Dhar, Poonam Rawat, Debprasad Chattopadhyay, Saroj Kanta Barik, Sharad Srivastava Dec 2021

In-Silico Efficacy Of Potential Phytomolecules From Ayurvedic Herbs As An Adjuvant Therapy In Management Of Covid-19, Bhanu Kumar, Ankita Misra, Satyendra Pratap Singh, Yogeshwar Vikram Dhar, Poonam Rawat, Debprasad Chattopadhyay, Saroj Kanta Barik, Sharad Srivastava

Journal of Food and Drug Analysis

The recent COVID-19 outbreak caused by SARS-CoV-2 virus has sparked a new spectrum of investigations, research and studies in multifarious directions. Efforts are being made around the world for discovery of effective vaccines/drugs against COVID-19. In this context, Ayurveda, an alternative traditional system of medicine in India may work as an adjuvant therapy in compromised patients. We selected 40 herbal leads on the basis of their traditional applications. The phytomolecules from these leads were further screened through in-silico molecular docking against two main targets of SARS-CoV-2 i.e. the spike protein (S; structural protein) and the main protease (MPRO …

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Conducting Polymer-Based Sensors For Food And Drug Analysis, Chia-Hsin Lin, Jia-Hui Lin, Chien-Fu Chen, Yoshihiro Ito, Shyh-Chyang Luo Dec 2021

Conducting Polymer-Based Sensors For Food And Drug Analysis, Chia-Hsin Lin, Jia-Hui Lin, Chien-Fu Chen, Yoshihiro Ito, Shyh-Chyang Luo

Journal of Food and Drug Analysis

Conducting polymers (CPs) are a category of polymeric materials with conjugated main chains. The characteristic electrical and optical properties of CPs can be fine-tuned through controlling the doping states of CPs. Because of their long-term stability in water, CPs have been demonstrated as electroactive biointerfaces and electrode materials especially in aqueous environments. Serving as multifunctional interfaces and organic electrodes for the integration bioelectronics and devices, CPs have been studied and applied in various biological applications. This paper provides a review of conducting polymer–based electrochemical sensors, particularly those used in biological fields. General conducting polymers and derivatives and their main electrochemical …

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Recent Developments In Sensing Of Oversulfated Chondroitin Sulfate In Heparin. A Review ., Manivannan Madhu, Wei-Lung Tseng Dec 2021

Recent Developments In Sensing Of Oversulfated Chondroitin Sulfate In Heparin. A Review ., Manivannan Madhu, Wei-Lung Tseng

Journal of Food and Drug Analysis

Oversulfated chondroitin sulfate (OSCS), a non-natural sulfated glycosaminoglycan, recognizes as a significant containment in the pharmaceutical heparin, and it could trigger adverse reactions. Chromatography-, electrophoresis-, electrochemistry-, and spectroscopy-related techniques are currently available for accurate and precise analysis of a trace amount of OSCS in heparin. Recently, emerging studies focus on developing colorimetric and fluorescent probes to monitor OSCS containments in heparin. Therefore, this current review aims to describe the sensing principle and procedure of the reported probes that are sensitive and selective toward OSCS in heparin without the interferences of other sulfated glycosaminoglycans. The reported OSCS-specific probes are comprehensively discussed …

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Antibiotic Resistant Enterobacteriaceae In Milk Alternatives, Winnie Mukuna, Abdullah Ibn Mafiz, Bharat Pokharel, Aniume Tobenna, Agnes Kilonzo-Nthenge Dec 2021

Antibiotic Resistant Enterobacteriaceae In Milk Alternatives, Winnie Mukuna, Abdullah Ibn Mafiz, Bharat Pokharel, Aniume Tobenna, Agnes Kilonzo-Nthenge

Human Sciences Faculty Research

The consumption of non-dairy milk is on the rise due to health benefits. Although there is increasing inclination towards milk alternatives (MA), there is limited data on antibiotic resistant bacteria in these substitutes. The aim of this study was to investigate antimicrobial resistance of bacteria isolated from MA. A total of 138 extracts from almonds (n = 63), cashew nuts (n = 36), and soybeans (n = 39) were analyzed for Enterobacteriaceae. The identification of the bacteria was based on biochemical and PCR methods. Antibiotic sensitivity was determined by using the Kirby-Bauer disk diffusion technique. Overall, 31% (43 of 138) …

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Positive Correlation Between A3 Subunit Of Glycinin And Firmness Of Tofu Made From Soybeans Grown In Three Locations Over Two Years, Ruiqi Chen Dec 2021

Positive Correlation Between A3 Subunit Of Glycinin And Firmness Of Tofu Made From Soybeans Grown In Three Locations Over Two Years, Ruiqi Chen

Theses and Dissertations

Producing desirable firmness is important in manufacturing tofu from soybeans. This study’s objective was to explore the environmental impact (location and year) on soybean chemical components and identify the correlations between chemical composition and the firmness of tofu made from soybeans planted in three locations over two years. Seventeen soybean Plant Introductions (PI) from the USDA Soybean Germplasm Collection and eight check varieties were planted in Mississippi, Virginia and Missouri in 2017 and 2018. Protein subunit composition, protein secondary structure, phytic acid content, Ca2+ and Mg2+ content were determined. The result showed that A3 subunit content was …

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Implementing Food Science-Based Instruction In Career Technical Education Courses, Jasmine D. Hendrix Dec 2021

Implementing Food Science-Based Instruction In Career Technical Education Courses, Jasmine D. Hendrix

Theses and Dissertations

Students are exposed to food concepts in agriculture-based career technical education (CTE) courses which provide a gateway for students to become more aware of food science career pathways. Professional development for Mississippi (MS) CTE teachers is needed to effectively implement food science-based instruction since there is not a food science curriculum framework adopted in MS. The objective of this study was to assess a food science professional development training for MS CTE teachers that would increase their self-perceived knowledge of food science, self-perceived ability to conduct food science skills, and their self-efficacy to implement food science-based instruction. Thirty-one teachers participated …

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Intermittent Antibiotic Treatment Accelerated The Development Of Colitis In Il-10 Knockout Mice, Shiyu Li, Yusong Jin, Abigail D. Cox, Dale Lee, Lavanya Reddivari Dec 2021

Intermittent Antibiotic Treatment Accelerated The Development Of Colitis In Il-10 Knockout Mice, Shiyu Li, Yusong Jin, Abigail D. Cox, Dale Lee, Lavanya Reddivari

Department of Food Science Faculty Publications

Many epidemiological studies suggest an association between antibiotic exposure and the development of inflammatory bowel disease [IBD]. However, the majority of these studies are observational and still the question remains, “Does the specific antibiotic administration regimen play a role in the development of colitis?” This study aimed to compare the possible effects of continuous and intermittent antibiotic exposure on the development of colitis using a colitis-susceptible IL-10 knockout [IL-10–/–] mouse model.

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