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Full-Text Articles in Other Cell and Developmental Biology

Hyper Stable Variants Of Fgf-1-Fgf-2 Dimer, Madison Shields Mcclanahan May 2022

Hyper Stable Variants Of Fgf-1-Fgf-2 Dimer, Madison Shields Mcclanahan

Chemistry & Biochemistry Undergraduate Honors Theses

Fibroblast Growth Factors (FGFs), including FGF-1 and FGF-2, are proteins that play a crucial role in cell proliferation, cell differentiation, cell migration, and tissue repair. FGF-1 and FGF-2 are useful in accelerating the healing process in the human body; however, these proteins are naturally thermally unstable, resulting in a relatively low half-life in vivo. 1,8 In efforts to improve the stability of this protein, FGF-1 and FGF-2 proteins are engineered by combining the amino acid sequences of the two proteins to form a heterodimer and obtain novel properties. These two FGF variants are chosen for their specific wound healing capabilities. …


Mitochondrial Deletions And Their Disease-Causing Effects, Austin Bell May 2020

Mitochondrial Deletions And Their Disease-Causing Effects, Austin Bell

Biological Sciences Undergraduate Honors Theses

The mitochondria perform a plethora of important functions within the cell, with one of the most paramount being ATP production. Deregulation of its function can have dire consequences on cellular functions. Mutations such as deletions within the mitochondrial DNA (mtDNA) can cause disease within the patients affected. These diseases often affect children, causing symptoms such as gradual loss of eyesight and hearing, diabetes, and other problems that lower the quality of life. The mitochondria are also very dynamic organelles that undergo rounds of fission and fusion to keep up with the metabolic needs of cells, necessitating a homeostatic balance between …


Reproductive Performance Of Female White-Tailed Deer On Holla Bend National Wildlife Refuge, Thomas A. Nelson Jan 1991

Reproductive Performance Of Female White-Tailed Deer On Holla Bend National Wildlife Refuge, Thomas A. Nelson

Journal of the Arkansas Academy of Science

Aspects of the reproductive biology of female white-tailed deer (Odocoileus virginianus) on Holla Bend National Wildlife Refuge were investigated by examining the reproductive tracts of 121 deer harvested during the 1985-90 archery seasons. The presence of corpora albicantia in yearlings suggested that 27% of female fawns conceived, producing a mean of 1.0 ova/breeding fawn. Pregnancy rates among yearlings and adults averaged 94% and 97%, respectively. Ovulation rates averaged 1.4 and 2.0 ova/female among yearlings and adults. Some females were ovulating in early-October, but the earliest conceptions occurred during the last week of October. The peak breeding period for yearlings and …