Open Access. Powered by Scholars. Published by Universities.®
- Discipline
-
- Medicine and Health Sciences (98)
- Medical Specialties (63)
- Oncology (60)
- Hematology (54)
- Cell Biology (30)
-
- Biochemistry, Biophysics, and Structural Biology (19)
- Genetics and Genomics (16)
- Immunology and Infectious Disease (15)
- Biology (14)
- Immunotherapy (13)
- Bioinformatics (12)
- Molecular Biology (12)
- Chemicals and Drugs (11)
- Biochemistry (8)
- Diseases (8)
- Genetics (8)
- Medical Sciences (8)
- Pharmacology, Toxicology and Environmental Health (7)
- Pharmacy and Pharmaceutical Sciences (7)
- Physical Sciences and Mathematics (7)
- Amino Acids, Peptides, and Proteins (6)
- Biotechnology (6)
- Laboratory and Basic Science Research (6)
- Molecular Genetics (6)
- Analytical, Diagnostic and Therapeutic Techniques and Equipment (5)
- Genomics (5)
- Other Pharmacy and Pharmaceutical Sciences (5)
- Institution
-
- King Faisal Specialist Hospital & Research Center (52)
- The Texas Medical Center Library (15)
- University of Texas Rio Grande Valley (12)
- Thomas Jefferson University (10)
- University of Kentucky (6)
-
- Chapman University (5)
- Virginia Commonwealth University (5)
- Dartmouth College (4)
- Medical University of South Carolina (4)
- University of New Hampshire (3)
- West Virginia University (3)
- Claremont Colleges (2)
- Michigan Technological University (2)
- Old Dominion University (2)
- Roseman University of Health Sciences (2)
- Universitas Indonesia (2)
- University of Arkansas, Fayetteville (2)
- University of Connecticut (2)
- University of New Mexico (2)
- American University in Cairo (1)
- Bard College (1)
- Belmont University (1)
- California State University, San Bernardino (1)
- City University of New York (CUNY) (1)
- Clemson University (1)
- Faculty of Engineering, Mansoura University (1)
- Georgia Southern University (1)
- Kennesaw State University (1)
- Liberty University (1)
- Loyola University Chicago (1)
- Keyword
-
- Cancer (15)
- Breast cancer (13)
- Immunotherapy (11)
- Humans (6)
- Bioinformatics (5)
-
- Metastasis (5)
- Apoptosis (4)
- Chemotherapy (4)
- Pancreatic cancer (4)
- Tumor (4)
- Angiogenesis (3)
- Cell Line, Tumor (3)
- Cell line (3)
- Colorectal Cancer (3)
- Hypoxia (3)
- Lung cancer (3)
- ROS (3)
- Animals (2)
- Biology (2)
- Biomarkers (2)
- Cancer Biomarkers (2)
- Cancer biology (2)
- Cell cycle (2)
- Colon cancer (2)
- DNA damage repair (2)
- DNA replication (2)
- EMT (2)
- Epigenetic (2)
- Extracellular Matrix (2)
- FLT3 (2)
- Publication
-
- Hematology/Oncology and Stem Cell Therapy (52)
- Dissertations & Theses (Open Access) (15)
- Research Symposium (11)
- Department of Pharmacology, Physiology, and Cancer Biology Faculty Papers (6)
- Theses and Dissertations (5)
-
- Dartmouth College Ph.D Dissertations (4)
- MUSC Theses and Dissertations (4)
- Theses and Dissertations--Toxicology and Cancer Biology (4)
- Electronic Theses and Dissertations (3)
- Graduate Theses, Dissertations, and Problem Reports (3)
- Honors Theses and Capstones (3)
- Annual Research Symposium (2)
- CMC Senior Theses (2)
- Department of Pathology, Anatomy, and Cell Biology Faculty Papers (2)
- Dissertations, Master's Theses and Master's Reports (2)
- Honors Scholar Theses (2)
- Kimmel Cancer Center Faculty Papers (2)
- Pharmacy Faculty Articles and Research (2)
- All Theses (1)
- Bioelectrics Publications (1)
- Biological Sciences Undergraduate Honors Theses (1)
- Biology ETDs (1)
- Biology, Chemistry, and Environmental Sciences Faculty Articles and Research (1)
- Biomedical Sciences ETDs (1)
- Biotechnology Theses (1)
- Chancellor’s Honors Program Projects (1)
- Chemistry & Biochemistry Faculty Publications (1)
- Chemistry & Biochemistry Undergraduate Honors Theses (1)
- Dissertations, Theses, and Capstone Projects (1)
- Doctoral Dissertations (1)
- Publication Type
Articles 151 - 162 of 162
Full-Text Articles in Cancer Biology
Analysis Of Biologically Effective Dose For Retroactive Yttrium-90 Trans-Arterial Radioembolization Treatment Optimization, Mj Lindsey
CMC Senior Theses
Trans-arterial radioembolization (TARE) is a protracted modality of radiation therapy where radionuclides labeled with Yttrium-90 (90Y) are inserted inside a patient's hepatic artery to treat hepatocellular carcinoma (HCC). While TARE has been shown to be a clinically effective and safe treatment, there is little understanding of the radiobiological relationship between absorbed dose and tissue response, and thus there is no dosimetric standard for treatment planning. The Biologically Effective Dose (BED) formalism, derived from the Linear-Quadratic model of radiobiology, is used to weigh the absorbed dose by the time pattern of delivery. BED is a virtual dose that can …
The Links To Cancer: How Golf Became Dangerous And What We Can Do To Save The Game, Meredith Boos
The Links To Cancer: How Golf Became Dangerous And What We Can Do To Save The Game, Meredith Boos
Undergraduate Theses, Professional Papers, and Capstone Artifacts
This study is a comprehensive meta-analysis on health claims linked to exposure to golf courses, more specifically the chemicals used to maintain their appearance. It provides a brief history of the golf industry and how its growth exacerbated the environmental impact as well as an explanation of the legal landscape that will affect golf course management. Golf courses can disrupt local ecologies, contaminate ground water, rivers, lakes and streams with run-off, and be responsible for the bioaccumulation of chemicals which remain dangerous for decades. Despite the adverse effects of golf courses on the environment, there remains an opportunity to transform …
Visualization And Characterization Of The Immunological Synapse Between Chlorotoxin Chimeric Antigen (Cltx-Car) Redirected T Cells And Targeted Glioblastoma Tumors, Arianna Livi
CMC Senior Theses
Chimeric Antigen Receptor T (CAR-T) cells have demonstrated anti-tumor activity against aggressive and invasive cancers such as glioblastoma (GBM); however, clinical response rates remain low in clinical trial studies. Tumor heterogeneity and tumor microenvironment conditions pose significant challenges for treatment of GBM, thus continuous optimization of CAR-T cell therapies and identification of novel, widely expressed, and highly specific GBM antigens are vital to better patient outcomes. A newly developed CAR-T cell construct incorporating chlorotoxin (CLTX) as the targeting domain exhibited broad GBM-targeting capabilities and elicited potent cytotoxic effects during preclinical studies and is currently being tested in a phase I …
Cell Signaling And Stress Response In The Yeast Saccharomyces Cerevisiae: A Study Of Snf1, Scott E. Arbet Ii
Cell Signaling And Stress Response In The Yeast Saccharomyces Cerevisiae: A Study Of Snf1, Scott E. Arbet Ii
Graduate Theses, Dissertations, and Problem Reports
Saccharomyces cerevisiae are yeast that are unicellular eukaryotic organisms that are well studied as a model organism for understanding fundamental cellular processes. The ability of yeast to sense nutrient availability is crucial for their survival, growth, and reproduction. Yeast cells use various mechanisms to sense and respond to nutrient availability, including transporter-mediated uptake, receptor-mediated signaling, and sensing of metabolites. The subcellular localization of nutrient-sensing components is crucial for yeast function in nutrient sensing and signaling. Protein complexes, such as the AMP-activated protein kinase (AMPK) pathway, in nutrient sensing and response, as well as the downstream effects of these pathways …
Cancer Promoting Neutrophil Extracellular Traps In The Pancreatic Ductal Adenocarcinoma Tumor Microenvironment, Abby Ivey
Graduate Theses, Dissertations, and Problem Reports
Pancreatic adenocarcinoma (PDAC) is a very aggressive disease with an overall survival rate at 12%. This poor outcome at diagnosis is in part due to the lack of effective treatment options. The aggressive disease and unique tumor microenvironment generated during disease initiation and progression has contributed to the lack of effective therapeutic options. Chemotherapy options have not improved overall survival substantially, the effectiveness of radiation therapy remains controversial, and immunotherapies provide little to no benefit when added to current standards of care. Thus, there is a critical need for new therapeutics that can either target PDAC alone or be added …
Escalated Dose Donor Lymphocyte Infusion Treatment In Patients With Primary Immune Deficiencies After Hsct With Reducedintensity Conditioning Regimen, Tahani Ali, Maryam Behfar, Rashin Mohseni, Pourya Salajegheh, Maged Kheder, Faihaa Abou-Fakher, Zeynab Nikfetrat, Fahimeh Jafari, Parisa Naji, Amir Ali Hamidieh
Escalated Dose Donor Lymphocyte Infusion Treatment In Patients With Primary Immune Deficiencies After Hsct With Reducedintensity Conditioning Regimen, Tahani Ali, Maryam Behfar, Rashin Mohseni, Pourya Salajegheh, Maged Kheder, Faihaa Abou-Fakher, Zeynab Nikfetrat, Fahimeh Jafari, Parisa Naji, Amir Ali Hamidieh
Hematology/Oncology and Stem Cell Therapy
Objective/Background: Mixed chimerism is a major concern after allogenic hematopoietic stem cell transplantation (HSCT) using a reduced-intensity conditioning (RIC) regimen in primary immunodeficiencies (PIDs). A donor lymphocyte infusion (DLI) escalating dose regimen has been developed with the aim of reducing toxicity while preserving efficacy. However, the graft-versus-host disease (GvHD) development remains the most common and adverse effect of DLI and continues to be a limiting factor in its application, especially nonmalignant diseases such as PIDs. We prospectively evaluated PID patients after HSCT using RIC in Children s Medical Center, who were candidates for an escalating dose of DLI for MC …
Unique Aspects Of Graft-Versus-Host-Disease Management In The Eastern Mediterranean Region: Report From The Eastern Mediterranean Blood And Marrow Transplantation Group: Special Report, Shahrukh Hashmi, Marwan Shaheen, Salman Adil, Parvez Ahmed, Syed Ahmed, Nour Ben Abdeljelil, Amal Alabdulwahab, Amal Albeihany, Saad Aldaama, Murtadha Al-Khabori, Salam Alkindi, Fahad Almohareb, Ahmed Alsaeed, Amal Alseraihy, Salem Alshemari, Mouhab Ayas, Naeem Chaudhri, Waleed Da’Na, David Dennison, Asma Elquessar, Alaa Elhaddad, Ahmad Ibrahim, Hasan Hashem, Wasil Jastaniah, Hani Mawardi, Amr Nassar, Tariq Satti, Lamia Torjemane, Khalid Tabbara, Hassan El Solh, Bassim Albeirouti, Mahmoud Aljurf
Unique Aspects Of Graft-Versus-Host-Disease Management In The Eastern Mediterranean Region: Report From The Eastern Mediterranean Blood And Marrow Transplantation Group: Special Report, Shahrukh Hashmi, Marwan Shaheen, Salman Adil, Parvez Ahmed, Syed Ahmed, Nour Ben Abdeljelil, Amal Alabdulwahab, Amal Albeihany, Saad Aldaama, Murtadha Al-Khabori, Salam Alkindi, Fahad Almohareb, Ahmed Alsaeed, Amal Alseraihy, Salem Alshemari, Mouhab Ayas, Naeem Chaudhri, Waleed Da’Na, David Dennison, Asma Elquessar, Alaa Elhaddad, Ahmad Ibrahim, Hasan Hashem, Wasil Jastaniah, Hani Mawardi, Amr Nassar, Tariq Satti, Lamia Torjemane, Khalid Tabbara, Hassan El Solh, Bassim Albeirouti, Mahmoud Aljurf
Hematology/Oncology and Stem Cell Therapy
Ther is no abstract for this article type.
Serum Electrolyte And Metabolic Changes During Conditioning Of Autologous Hematopoietic Stem Cell Transplantation In Patients With Autoimmune Diseases: A Prospective Study In A Single Institution., Brenda J. Méndez-Laureano, Moisés M. Gallardo-Pérez, Claudia Minutti-Zanella, Guillermo J. Ruiz-Argüelles
Serum Electrolyte And Metabolic Changes During Conditioning Of Autologous Hematopoietic Stem Cell Transplantation In Patients With Autoimmune Diseases: A Prospective Study In A Single Institution., Brenda J. Méndez-Laureano, Moisés M. Gallardo-Pérez, Claudia Minutti-Zanella, Guillermo J. Ruiz-Argüelles
Hematology/Oncology and Stem Cell Therapy
Background: A hematopoietic stem cell transplant (HSCT) includes a conditioning regimen which may cause unwanted metabolic changes. Objective: Analyze the changes in electrolytes, glucose, urea and glomerular filtration rate in patients with MS who underwent an autologous HSCT employing the “Mexican method”. Methods: Serum and urinary electrolytes, blood glucose, creatinine, uric acid and estimated glomerular filtration rate (eGFR) were prospectively assessed on days -11, - 9, and 0 in a group of 75 patients with multiple sclerosis (MS) receiving an autologous HSCT employing the “Mexican Method”, which includes high doses of both cyclophosphamide (Cy, 200 mg/Kg) and rituximab (1000 mg). …
Fam-Trastuzumab Deruxtecan (Enhertu) Induced Pyloric Perforation In Hormonal Receptor Positive/ Her2 Low Express Metastatic Breast Cancer., Taher Al-Tweigeri
Fam-Trastuzumab Deruxtecan (Enhertu) Induced Pyloric Perforation In Hormonal Receptor Positive/ Her2 Low Express Metastatic Breast Cancer., Taher Al-Tweigeri
Hematology/Oncology and Stem Cell Therapy
There is no abstract for this article.
What Are Factors Influencing On Life Space Mobility In Cancer Survivors After Hematopoietic Stem Cell Transplantation? -Physical Function, Depression, Fatigue, Neighborhood Walkability, Or Employment Status?, Junichiro Inoue, Takashi Saito, Daisuke Makiura, Rei Ono, Hisayo Doi, Kimikazu Yakushijin, Yoshitada Sakai
What Are Factors Influencing On Life Space Mobility In Cancer Survivors After Hematopoietic Stem Cell Transplantation? -Physical Function, Depression, Fatigue, Neighborhood Walkability, Or Employment Status?, Junichiro Inoue, Takashi Saito, Daisuke Makiura, Rei Ono, Hisayo Doi, Kimikazu Yakushijin, Yoshitada Sakai
Hematology/Oncology and Stem Cell Therapy
Background/Objective: The amount of physical activity in daily life is important to maintain the physical and mental health of cancer survivors after hematopoietic stem cell transplantation (HSCT). As the physical activity is considered to be limited by the life space mobility (LSM), it is more important to maintain and expand the LSM in post-HSCT survivors. The purpose of this study was to clarify the factors that affect the LSM in post-HSCT survivors. Methods: Thirty cancer survivors after HSCT (14 women, mean age 52.0±12.3 years, 196-3,017 days post-HSCT) were included in this cross-sectional study. Patient characteristics, employment status, life space (Life …
Comparison Of Cell Cycle Gene Expression Between Ovarian Cancer Cell Line Skov3 And Non-Cancerous Cell Lines, Akayla Weatherby
Comparison Of Cell Cycle Gene Expression Between Ovarian Cancer Cell Line Skov3 And Non-Cancerous Cell Lines, Akayla Weatherby
Dissertations, Master's Theses and Master's Reports
Roughly 1% of women will be diagnosed with ovarian cancer during their lifetime. There are many different factors that impact how likely someone is to develop ovarian cancer including age, lifestyle, and family history. Ovarian cancer, like all cancers, occurs due to the accumulation of cancer cells that result from errors in the cell cycle or its regulation. Here, we studied how cell cycle gene expression was altered in the epithelial-like ovarian cancer cell line SKOV3, as compared to the pre-cancerous ovarian cell line FT282, and the non-cancerous foreskin fibroblast cell line BJ5Ta. The three cell lines were synchronized into …
The Effects Of Cucurbitacin B And Silmitasertib On Metastasis And Itga6 Using The Zebrafish Tumor-Xenograft, Alexandra Griffis
The Effects Of Cucurbitacin B And Silmitasertib On Metastasis And Itga6 Using The Zebrafish Tumor-Xenograft, Alexandra Griffis
Electronic Theses and Dissertations
Ninety percent of cancer deaths are resultant from the metastasis of cancer cells. When cancer cells translocate through blood vessels or the lymphatic system, they may form tumors outside of their primary site. The processes of metastasis can begin quickly; after onset, metastasis is unforgiving, as it does not participate with the body’s physiological systems in an orderly way. In the past, our lab produced results indicating that a cell adhesion molecule, Integrin Alpha-6, may contribute to cancer cells' ability to metastasize. Integrins mediate interactions between the cell and the Extracellular Matrix (ECM), regulating cell attachment and cell migration. With …