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Cell and Developmental Biology Commons™
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Articles 2941 - 2943 of 2943
Full-Text Articles in Cell and Developmental Biology
Keratitis Contagiosa In Cattle, Frank S. Billings
Keratitis Contagiosa In Cattle, Frank S. Billings
School of Veterinary and Biomedical Sciences: Faculty Publications
This is not a new disease by any means, so far as the United States are concerned, nevertheless I have been unable to find any description of it in the literature at my command. While new to myself until the past Summer, there have been quite a number of reports of its existence, and complaints about it, from farmers and breeders of cattle in some of the live-stock journals of our western States. Under these circumstances, it would seem that a description of its clinical phenomena and gross pathological lesions may not be without scientific interest to the opthalmologist, and …
Inoculation—Vaccination, Frank S. Billings
Inoculation—Vaccination, Frank S. Billings
School of Veterinary and Biomedical Sciences: Faculty Publications
When one comes to discuss this question with the members of the profession as he casually meets them, he is often surprised to find how uncertain and clouded the prevailing ideas are upon the subject. In fact, the majority of physicians do not seem to have any clear conception of the act connected with the words “ inoculation ” and “ vaccination.”
Replicating Single-Cycle Adenovirus Vectors Generate Amplified Influenza Vaccine Responses, Catherine M. Crosby, William E. Matchett, Stephanie S. Anguiano-Zarate, Christopher A. Parks, Eric A. Weaver, Larry R. Pease, Richard J. Webby, Michael A. Barry
Replicating Single-Cycle Adenovirus Vectors Generate Amplified Influenza Vaccine Responses, Catherine M. Crosby, William E. Matchett, Stephanie S. Anguiano-Zarate, Christopher A. Parks, Eric A. Weaver, Larry R. Pease, Richard J. Webby, Michael A. Barry
Nebraska Center for Virology: Faculty Publications
Head-to-head comparisons of conventional influenza vaccines with adenovirus (Ad) gene-based vaccines demonstrated that these viral vectors can mediate more potent protection against influenza virus infection in animal models. In most cases, Ad vaccines are engineered to be replication-defective (RD-Ad) vectors. In contrast, replication-competent Ad (RC-Ad) vaccines are markedly more potent but risk causing adenovirus diseases in vaccine recipients and health care workers. To harness antigen gene replication but avoid production of infectious virions, we developed “single-cycle” adenovirus (SC-Ad) vectors. Previous work demonstrated that SC-Ads amplify transgene expression 100-fold and produce markedly stronger and more persistent immune responses than RD-Ad vectors …