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Articles 91 - 120 of 300
Full-Text Articles in Biology
Creepy Crawly Compensation: Examining The Costs Of Ectoparasite-Induced Compensatory Growth In Late-Stage Nestlings, Elliot Lusk
Creepy Crawly Compensation: Examining The Costs Of Ectoparasite-Induced Compensatory Growth In Late-Stage Nestlings, Elliot Lusk
Biology
When normal growth rates are suppressed, organisms may undergo a rapid period of increased growth in order to match the physical requirements of a developmental benchmark. This compensatory growth, however, is not without its costs, which can have varying consequences. In nestlings, a major benchmark is that of fledging, which requires advanced physical maturation. In previous studies, compensatory growth and some of its associated costs have been shown in prefledging nestlings but fledging-aged nestlings and the costs they may have sustained needs further study. Here we examine the costs of compensatory growth in late-stage European starling (Sturnus vulgaris) nestlings under …
Exotic Legume's Leaf Litter Beneficial To Prairie Plants, Asher Gardner
Exotic Legume's Leaf Litter Beneficial To Prairie Plants, Asher Gardner
Biology
Lespedeza cuneata is an invasive, non-native species of bush clover that is invading prairies where the native Lespedeza capitata grows. Both species of bush clover are legumes, which are nitrogen fixers. Legumes and their senescent leaves (i.e., “litter”) are well known for increasing levels of available nitrogen in the soil. However, the exotic L. cuneata also produces tannins that reduce the rate of germination in some prairie plants. The purpose of this study was to clarify whether these compounds in the litter of the invasive species of bush clover deter early growth in its native competitors, and to determine whether …
Potential Of Fungi Isolated From Diesel Contaminated Soil To Degrade Diesel, Oluwafemi Oyewole, Ramat Raji, Suzan Okeke, Gift Chukwuma, Japhet Yakubu
Potential Of Fungi Isolated From Diesel Contaminated Soil To Degrade Diesel, Oluwafemi Oyewole, Ramat Raji, Suzan Okeke, Gift Chukwuma, Japhet Yakubu
Tanzania Journal of Science
Diesel is a complex mixture and a common pollutant, consisting mainly of aliphatic hydrocarbons ranging from C9 to C23 and a number of aromatic compounds. The main purpose of this study was to isolate fungi from diesel contaminated soil for biodegradation of diesel contaminated soil. Two fungal species (Aspergillus flavus and Saccharomyces cerevisiae) were isolated from a diesel contaminated site using cultural and biochemical characterisation. The isolates were screened for their ability to utilize diesel as carbon source. The biodegradation rate of the fungi isolated was measured by determining the optical density using spectrophotometry. The fungal isolates were further tested …
Isolation And Quantification Of Flavonoids From Kigelia Africana (Lam.) Benth Fruit And Bark And Their Antiradical And Antibacterial Activities, Pamhidzai Dzomba, George Mhini
Isolation And Quantification Of Flavonoids From Kigelia Africana (Lam.) Benth Fruit And Bark And Their Antiradical And Antibacterial Activities, Pamhidzai Dzomba, George Mhini
Tanzania Journal of Science
Kigelia africana is an evergreen deciduous tree used in Zimbabwe folklore medicine for wound and diabetes ulcers healing. This paper reports the isolation and quantification of flavonoids from stem barks and fruits of K. africana as well as their antibacterial and antiradical activities. Flavonoids in ethanol and ethyl-acetate extracts were quantified using UV-Vis spectrophotometry and were found to be 213.490 ± 0.001 mg/L and 36.614 ± 0.001 mg/L, respectively per quercetin equivalent. The preparative and analytical thin layer chromatography was used to profile the flavonoids from fruits and barks using ethyl-acetate and petroleum ether (3:7 v/v) mobile solvent systems. Ethanol …
Antibacterial Activities Of Hyphaene Thebaica (Doum Palm) Fruit Extracts Against Intestinal Microflora And Potential Constipation Associated Pathogens In Yola Metropolis, Nigeria, Joel Ewansiha, Chidimma Ugo, Damaris Kolawole, Lilian Orji
Antibacterial Activities Of Hyphaene Thebaica (Doum Palm) Fruit Extracts Against Intestinal Microflora And Potential Constipation Associated Pathogens In Yola Metropolis, Nigeria, Joel Ewansiha, Chidimma Ugo, Damaris Kolawole, Lilian Orji
Tanzania Journal of Science
This study aimed at determining the antibacterial activities of Hyphaene thebaica fruit extracts against some intestinal constipation associated bacteria. Qualitative analysis of some phytochemical constituents, agar well diffusion and broth dilution methods were used to determine the zones of inhibition and minimum inhibitory concentration (MIC) of the plant extracts. Phytochemical components viz flavonoids, saponins, terpenoids, tannins, phenols, alkaloids, glycosides and steroids were detected in the plant extracts, and the test organisms were susceptible to the plant extracts. The diameter zone of inhibition (DZI) obtained with n-hexane extract ranged from 15.10 ± 0.51 mm to 2.0 ± 0.55 mm against K. …
Wastewater Clarification And Microbial Load Reduction Using Agro-Forestry And Agricultural Wastes, Joel Njewa, Ephraim Vunain, Timothy Biswick
Wastewater Clarification And Microbial Load Reduction Using Agro-Forestry And Agricultural Wastes, Joel Njewa, Ephraim Vunain, Timothy Biswick
Tanzania Journal of Science
Five agro-wastes, namely: cassava peels, Irish potato peels, Jatropha curcas seeds, Moringa oleifera seeds and rice husks were investigated as plant-based coagulants for turbidity and microbial load removal from sewage wastewater. Moringa oleifera and Jatropha curcas seeds before usage were defatted with 95% ethanol and the active coagulating component was extracted with 1.0 M NaCl. For the other three agro-wastes, their ashes were evaluated for turbidity and microbial load removal. The ash was prepared through pyrolysis of the raw biomass at a temperature of 800 °C for 3 h. The effect of pH, coagulant dose, settling time on turbidity reduction …
Cellulase-Producing Bacteria Isolated From Mufindi Paper Mill Industrial Effluent, Iringa Tanzania, Erick Sinza, Aneth Mwakilili, Cyprian Mpinda, Sylvester Lyantagaye
Cellulase-Producing Bacteria Isolated From Mufindi Paper Mill Industrial Effluent, Iringa Tanzania, Erick Sinza, Aneth Mwakilili, Cyprian Mpinda, Sylvester Lyantagaye
Tanzania Journal of Science
Effluent and effluent-contaminated soil samples collected from Mufindi Paper Mill Limited, Iringa Tanzania were investigated for the presence of cellulolytic bacteria. The components of cellulase are endoglucanase, exoglucanase and β-glucosidase and these are very important for complete hydrolysis of cellulose to glucose monomers. Isolates were grown on nutrient agar and screened for cellulolytic activity on carboxymethylcellulose (CMC) agar plates using Gram’s iodine solution. Cellulases activities; endoglucanase, exoglucanase and β-glucosidase were assayed using CMC, avicel and cellobiose substrates, respectively by dinitrosalicyclic acid method. Out of 17 cellulolytic isolates obtained, crude enzyme extracts of only five isolates expressed all cellulases activities, the …
Acetylcholinesterase Activity And Oxidative Stress Biomarkers In Fiddler Crabs (Austruca Occidentalis) Along The Coastal Mangrove Areas Of Dar Es Salaam, Tanzania, James Lugata, Flora Stephano, Harishchandra Pratap
Acetylcholinesterase Activity And Oxidative Stress Biomarkers In Fiddler Crabs (Austruca Occidentalis) Along The Coastal Mangrove Areas Of Dar Es Salaam, Tanzania, James Lugata, Flora Stephano, Harishchandra Pratap
Tanzania Journal of Science
The aquatic organisms such as crustaceans serve as bioindicators of the environmental stressors which affect the aquatic ecosystems. The present study assessed environmental health status through fiddler crabs (Austruca occidentalis) towards oxidative stress biomarkers and AChE activity in mangroves with different levels of salinity and environmental contamination. Fiddler crabs were collected from Mtoni Kijichi, Kunduchi and Mbweni, which experience different levels of contamination from high to low along the Dar es Salaam coastline. Malondialdehyde the biomarker of oxidative stress was analysed by lipid peroxidation (LPO) assay and AChE activity was tested using Ellman assay in the crab tissues (muscles, hepatopancreas …
Effects Of Time On Ph, Total Bacteria Counts, And Total Hydrocarbon Contents In The Bioremediation Of Crude Oil Contaminated Soil Using Indigenous Bio-Stimulants, Ita Uwidia, Osalodion Uwidia
Effects Of Time On Ph, Total Bacteria Counts, And Total Hydrocarbon Contents In The Bioremediation Of Crude Oil Contaminated Soil Using Indigenous Bio-Stimulants, Ita Uwidia, Osalodion Uwidia
Tanzania Journal of Science
This study was conducted to investigate the effect of time on pH, total bacteria counts, and total hydrocarbon contents in the bioremediation of crude oil contaminated soil using pig waste and sawdust as bio-stimulants. Dried soil samples (500 g each) were weighed each into seven different plastic bowls, and each bowl was contaminated with 10 g of crude oil. Six of the contaminated soil samples in six of the plastic bowls were amended with a combination of pig waste and sawdust as bio-stimulants in the ratio of 1:1 in amounts of 150 g, 125 g, 100 g, 75 g, 50 …
Floristic Studies On Herbaceous And Grass Species Growing In The University Of Lagos, Nigeria, George Nodza, Ruth Anthony, Temitope Onuminya, Oluwatoyin Ogundipe
Floristic Studies On Herbaceous And Grass Species Growing In The University Of Lagos, Nigeria, George Nodza, Ruth Anthony, Temitope Onuminya, Oluwatoyin Ogundipe
Tanzania Journal of Science
Rapid loss in flora diversity, changing patterns of vegetation and land use patterns in the University of Lagos Akoka campus has necessitated investigation on the herb and grass species so as to determine their compositions, structures and diversity within the area. Twenty sampling plots of 10m x 10m each were studied in five selected locations using random sampling. The samples were counted and identified using Flora of West Tropical Africa. A total of 75 taxa (herbs = 53 spp and grasses = 22 spp) belonging to 26 families and 64 genera were recorded in the area. Of all the families, …
Geometric Morphometric Comparison Of Abu Mullet, Planiliza Abu (Heckel, 1843) Populations In Bushehr Basin, Iran: Fatemeh Shabaninejad, Yazdan Keivany, Dara Bagheri, Fatemeh Shabaninejad, Yazdan Keivany, Dara Bagheri
Geometric Morphometric Comparison Of Abu Mullet, Planiliza Abu (Heckel, 1843) Populations In Bushehr Basin, Iran: Fatemeh Shabaninejad, Yazdan Keivany, Dara Bagheri, Fatemeh Shabaninejad, Yazdan Keivany, Dara Bagheri
Tanzania Journal of Science
Many fish behavior and habitats could be defined based on the fish morphology, thus, using the fish body shape, in addition to its genetic characteristics, could be used to infer the type of fish habitat and its characteristics. This study aimed to compare the body shapes of five populations of abu mullet, Planiliza abu (Heckel, 1843), in Bushehr basin using geometric morphometric method. Some 162 specimens from Hendijan, Genaveh, Helleh, Kaki and Mond rivers were used. Three morphometric characters, total length (TL), fork length (FL) and standard length (SL) were measured. Samples were photographed from the left side, then 18 …
Notch Regulates Vascular Collagen Iv Basement Membrane Through Modulation Of Lysyl Hydroxylase 3 Trafficking, Stephen J.B. Gross
Notch Regulates Vascular Collagen Iv Basement Membrane Through Modulation Of Lysyl Hydroxylase 3 Trafficking, Stephen J.B. Gross
Electronic Theses and Dissertations
Collagen type IV (Col IV) is a basement membrane protein associated with early blood vessel morphogenesis and is essential for blood vessel stability. Defects in vascular Col IV deposition are the basis of heritable disorders, such as small vessel disease, marked by cerebral hemorrhage and drastically shorten lifespan. To date, little is known about how endothelial cells regulate the intracellular transport and selective secretion of Col IV in response to angiogenic cues, leaving a void in our understanding of this process. Our aim was to identify trafficking pathways that regulate Col IV deposition during angiogenic blood vessel development. We have …
Understanding Patterns And Functional Impacts Of An Invasive Tree And Its Biological Control In A Riparian System, Annie L. Henry
Understanding Patterns And Functional Impacts Of An Invasive Tree And Its Biological Control In A Riparian System, Annie L. Henry
Electronic Theses and Dissertations
Invasive species have become an inextricable part of the landscape, particularly in riparian plant communities, and removal is often a key component of restoration programs. Biological control (biocontrol) is a method of removal that is often both efficient and effective. However, the impact of biocontrol on target species and indirect effects from invasive species removal can be hard to predict. While monitoring the impact of invasive species removal usually involves some species-based assessment such as changes in diversity, historically dominant species or native species, these strategies do not typically provide insight into the mechanisms underlying plant community response to removal. …
Development Of Endoplasmic Reticulum Targeted Probes And Red Fluorescent Probes For Detecting Zinc, Drew Maslar
Development Of Endoplasmic Reticulum Targeted Probes And Red Fluorescent Probes For Detecting Zinc, Drew Maslar
Electronic Theses and Dissertations
Zinc (Zn2+) is the second most abundant transition metal in the body and is important in various biological functions. Fluorescent sensors based on circularly permuted fluorescent proteins (cpFPs) have been previously made to detect labile, or unbound, Zn2+ within the cytoplasm of cells. These sensors have proven invaluable for studying Zn2+, however, these sensors are limited to their use in the cytoplasm and by the fact that only green cpFP have been utilized to create fluorescent Zn2+ sensors. In this thesis, we use a combination of peptide targeting sequences, site-directed mutagenesis, and rational design …
Optimized Microbial Recombinant Production Of Hiv-1 Anti-Envelope Antibody Fragments With Applications To Single Particle Tracking Of Virus Assembly, Merissa Michelle Bruns
Optimized Microbial Recombinant Production Of Hiv-1 Anti-Envelope Antibody Fragments With Applications To Single Particle Tracking Of Virus Assembly, Merissa Michelle Bruns
Electronic Theses and Dissertations
In my findings, I have established a set series of protocols to recombinantly produce, purify and apply various fluorescent probes in vitro for the fluorescent labeling and study of the human immunodeficiency virus type 1 (HIV-1) envelope (Env) protein during HIV viral assembly. There remains insufficient knowledge about the molecular dynamics and interactions of HIV-1 Env protein with its counterpart, Gag, on the inner host cell surface during assembly of a mature virus particle. There also remains an insufficient amount of data for the understanding and clarification of the mechanism of action of a known host cell HIV-1 restriction factor, …
Analyses Of Coyote (Canis Latrans) Consumption Of Anthropogenic Material And Dietary Composition In Urban And Non-Urban Habitats, Audrey A. Hayes
Analyses Of Coyote (Canis Latrans) Consumption Of Anthropogenic Material And Dietary Composition In Urban And Non-Urban Habitats, Audrey A. Hayes
Browse all Theses and Dissertations
Coyotes are a generalist species that have adapted to nearly every terrestrial habitat in the United States. The species’ success is heavily attributed to their omnivorous diets and tolerance for environments that are regularly disturbed. Because the larger predator species that typically act as apex predators are sensitive to highly fragmented landscapes, the coyote is the functioning apex predator in many ecosystems where large predators, such as wolves, have been extirpated. The coyotes’ ecological role in urban ecosystems has received much attention in the last few decades as the species’ presence in cities and suburbs has increased, along with human-coyote …
Interleukin-2 Receptor Alpha Nuclear Localization Impacts Vascular Smooth Muscle Cell Function And Phenotype, Kristie Nhi Dinh
Interleukin-2 Receptor Alpha Nuclear Localization Impacts Vascular Smooth Muscle Cell Function And Phenotype, Kristie Nhi Dinh
Browse all Theses and Dissertations
Atherosclerosis is responsible for 50% of all deaths in western society and is the main cause of cardiovascular diseases (Pahwa et al. 2020). Vascular smooth muscle cells (VSMC) play a vital role in the development of atherosclerotic plaques; this is due to their ability to proliferate and migrate in response to inflammation and damage to arteries’ inner linings. To further understand what causes these cells to proliferate and migrate, our lab has previously found that VSMC express all three subunits of the IL-2 receptor (IL-2R). Out of these three subunits, IL-2Rα appeared to change the most depending on the phenotype …
Antibacterial And Anti-Hiv-1 Reverse Transcriptase Activities Of Selected Medicinal Plants And Their Synthesized Zinc Oxide Nanoparticles, Rose J. Masalu, Sai Ngassa, Grace A. Kinunda, Cyprian B. Mpinda
Antibacterial And Anti-Hiv-1 Reverse Transcriptase Activities Of Selected Medicinal Plants And Their Synthesized Zinc Oxide Nanoparticles, Rose J. Masalu, Sai Ngassa, Grace A. Kinunda, Cyprian B. Mpinda
Tanzania Journal of Science
Human Immunodeficiency Virus infection and Acquired Immune Deficiency Syndrome (HIV/AIDS) and associated opportunistic infections are still global health concerns. Traditional medicines have been used for managing these infections, with little about their biological activities being known. This study evaluated antimicrobial and anti-HIV-1 Reverse Transcriptase (RT) activities of medicinal plants; Harungana madagascariensis, Sapium ellipticum, Pseudospondias microcarpa, Capparis erythrocarpos, and Plectranthus barbatus; and activities of zinc oxide nanoparticles synthesized from aqueous extracts of H. madagascariensis. Results revealed that aqueous and ethyl acetate extracts of H. madagascariensis, S. ellipticum, P. microcarpa; and ethyl acetate extracts from P. barbatus exhibited minimum inhibitory concentrations ranging …
Detection Of Extended Spectrum Beta-Lactamase Producing Escherichia Coli From Urinary Tract Infection In General Hospital, Minna, Nasiru U. Adabara, Naimat D. Bakinde, Sherifat O. Enejiyon, Tijani Salami, Doosuur Iorzua
Detection Of Extended Spectrum Beta-Lactamase Producing Escherichia Coli From Urinary Tract Infection In General Hospital, Minna, Nasiru U. Adabara, Naimat D. Bakinde, Sherifat O. Enejiyon, Tijani Salami, Doosuur Iorzua
Tanzania Journal of Science
Possession of virulence factors such as extended spectrum beta lactamase (ESBL) by pathogens generally exacerbates morbidity as well as increases healthcare costs. This study determined the production of ESBL among Escherichia coli isolated from the urinary tracts of subjects attending General Hospital, Minna, Nigeria. One hundred and fifty (150) urine samples were collected from subjects and cultured on CLED agar for the isolation of E. coli. Antibiotic susceptibility testing was done using Kirby Bauer disk diffusion method, while the phenotypic identification of ESBL-producing strains was carried out using double disk synergy test. All results were interpreted based on Clinical and …
Improved Image Quality In Digital Mammography Using Anti-Scatter Grids, Samson O. Omondi, Peter K. Msaki, Ramadhan R. Kazema, Innocent J. Lugendo
Improved Image Quality In Digital Mammography Using Anti-Scatter Grids, Samson O. Omondi, Peter K. Msaki, Ramadhan R. Kazema, Innocent J. Lugendo
Tanzania Journal of Science
Curability and effective management of breast cancer are dependent on its early detection. Early diagnosis strategies focus on providing timely access to breast cancer treatments by reducing barriers and improving access to effective early diagnosis. Mammography is the screening method of choice but suffers from degrading effects of scatter photons obstructing visualization of ductal carcinoma in situ and micro-calcifications in the breast. Quantitative evaluation of scatter suppression by anti-scatter grid using the beam stopper method has been investigated. Breast tissue equivalent phantom, polymethyl methacrylate was evaluated at X-ray mammographic nominal energy ranges. The anti-scatter grid used had aluminium interspace material …
Antibacterial Activities Of The Extracts Of Allium Sativum (Garlic) And Allium Cepa (Onion) Against Selected Pathogenic Bacteria, Sherifat O. Enejiyon, Al-Hassan A. Abdulrahman, Abdulameen S. Adedeji, Ramatu Abdulsalam, Mary U. Oyedum
Antibacterial Activities Of The Extracts Of Allium Sativum (Garlic) And Allium Cepa (Onion) Against Selected Pathogenic Bacteria, Sherifat O. Enejiyon, Al-Hassan A. Abdulrahman, Abdulameen S. Adedeji, Ramatu Abdulsalam, Mary U. Oyedum
Tanzania Journal of Science
Although many antibiotics have been developed against bacterial diseases, the problems of antibiotic resistance and toxicity have made the continuous search for newer drugs an existential necessity. This study determined the phytochemical components and antibacterial activities of Allium sativum and Allium cepa against Salmonella typhi, Staphylococcus aureus, Streptococcus pneumoniae, Klebsiella pneumoniae and Escherichia coli. The phytochemical analysis was carried out using standard methods. The antibacterial activities of the aqueous, ethanol and acetone extracts of both plants at different concentrations were determined against all the test organisms using agar well diffusion method. All the extracts were found to contain important phytochemicals …
Assessment Of Genetic Diversity Of The Wild Rice (Oryza Longistaminata) Populations In Tanzania Using Microsatellite Markers, Hashim M. Mangosongo, Emerald E. Mneney, Jagger Harvey, Martina Kyallo
Assessment Of Genetic Diversity Of The Wild Rice (Oryza Longistaminata) Populations In Tanzania Using Microsatellite Markers, Hashim M. Mangosongo, Emerald E. Mneney, Jagger Harvey, Martina Kyallo
Tanzania Journal of Science
The genetic diversity of 132 samples of the perennial wild rice (Oryza longistaminata) populations from selected districts (Bagamoyo, Kibaha, Kilombero and Mbarali) in Tanzania was evaluated using twenty eight microsatellite markers. Genomic DNA was extracted using standard protocols. Polymerase Chain Reaction (PCR) was carried out in a total reaction volume of 10 µL, using Touchdown protocol. It was found that all 28 microsatellite markers generated polymorphic patterns, with average Polymorphic Information Content (PIC) value of 0.631. Moreover, a total of 243 alleles were detected by the 28 markers, with average of 8.68 alleles per marker. The percentages of genetic variations …
Craniometrics Analysis For Ontogenetic Physiognomy And Sexual Dimorphism In Emin’S Silvery Mole-Rats (Heliophobius Argenteocinereus Emini: Bathyergidae) From Tanzania, Jestina V Katandukila
Craniometrics Analysis For Ontogenetic Physiognomy And Sexual Dimorphism In Emin’S Silvery Mole-Rats (Heliophobius Argenteocinereus Emini: Bathyergidae) From Tanzania, Jestina V Katandukila
Tanzania Journal of Science
Emin’s silvery mole-rat, the Heliophobius argenteocinereus emini belongs to a family Bathyergidae. The Heliophobius argenteocinereus emini (Noak, 1894) isinformation on ontogenetic physiognomy and status of sexual dimorphism in H. a. emini is missing. The present study intended to fill gaps on ontogenetic characteristics and status of sexual dimorphism in these mole-rats by comprehensively examining 55 skulls. Based on teeth eruption and wear, the dental formula of 1/1, 0/0, 1/1, 3/3 is reported for the first time, and subsequently established eight relative age classes. This information was key to the assessment of ontogenetic variations between sexes and age classes. The multidisciplinary …
Comparison Of Seaweed Growth, Fish Abundance And Diversity In Deep Water Floating Raft With Tubular Nets And Shallow Water Off-Bottom Lines Seaweed Farms, Batuli M. Yahya, Saleh A. S. Yahya, Aviti J. Mmochi, Narriman S. Jiddawi
Comparison Of Seaweed Growth, Fish Abundance And Diversity In Deep Water Floating Raft With Tubular Nets And Shallow Water Off-Bottom Lines Seaweed Farms, Batuli M. Yahya, Saleh A. S. Yahya, Aviti J. Mmochi, Narriman S. Jiddawi
Tanzania Journal of Science
This study compared the growth performance of Eucheuma denticulatum, fish abundance and diversity between deep water (using tubular nets) versus shallow water (off-bottom) seaweed farming methods. For each farming method, three plots were set and fish abundance, diversity and seaweed growth rates were measured at intervals of 15 days. Belt transects measuring 10 m x 4 m each, were established on seaweed farms for fish observations. Fish were identified to the lowest possible taxonomic level by underwater census. The results showed that the growth rate of E. denticulatum in deep water farms was slightly higher at an average daily growth …
Anti-Diabetic Activity Of Chrysophyllum Albidum (G. Don) Stem Bark In Alloxan-Induced Type 1 Diabetic Female Wistar Rats, Babalola Ola Yusuf, Musa Toyin Yakubu, Musbau Adewumi Akanji
Anti-Diabetic Activity Of Chrysophyllum Albidum (G. Don) Stem Bark In Alloxan-Induced Type 1 Diabetic Female Wistar Rats, Babalola Ola Yusuf, Musa Toyin Yakubu, Musbau Adewumi Akanji
Tanzania Journal of Science
Anti-diabetic activity of aqueous extract of Chrysophyllum albidum stem bark (AECASB) in female Wistar rats was investigated to confirm or refute the purported use and the underlying mechanism of action of C. albidum stem bark in the management of type 1 diabetes in Nigeria traditional medicine. Seventy female rats (180.60 ± 8.50 g) were assigned into seven groups. Rats in Group 1 (non-diabetic) were orally administered 1 mL of distilled water, while animals in Groups 2-7 were made diabetic and orally administered 1 mL of distilled water, 2.5 mg/kg body weight (bwt) of glibenclamide, 25, 50, 100 and 200 mg/kg …
Morphological Evidence For An Oral Venom System In Caecilian Amphibians, Pedro Luiz Mailho-Fontana, Marta Maria Antoniazzi, Cesar Alexandre, Daniel Carvalho Pimenta, Juliana Mozer Sciani, Edmund D. Brodie Jr., Carlos Jared
Morphological Evidence For An Oral Venom System In Caecilian Amphibians, Pedro Luiz Mailho-Fontana, Marta Maria Antoniazzi, Cesar Alexandre, Daniel Carvalho Pimenta, Juliana Mozer Sciani, Edmund D. Brodie Jr., Carlos Jared
Biology Faculty Publications
Amphibians are known for their skin rich in glands containing toxins employed in passive chemical defense against predators, different from, for example, snakes that have active chemical defense, injecting their venom into the prey. Caecilians (Amphibia, Gymnophiona) are snake-shaped animals with fossorial habits, considered one of the least known vertebrate groups. We show here that amphibian caecilians, including species from the basal groups, besides having cutaneous poisonous glands as other amphibians do, possess specific glands at the base of the teeth that produce enzymes commonly found in venoms. Our analysis of the origin of these glands shows that they originate …
The Effects Of Milk Components On Lactoperoxidase Activity, Leonard Fweja, Michael Lewis, Alistair Grandison
The Effects Of Milk Components On Lactoperoxidase Activity, Leonard Fweja, Michael Lewis, Alistair Grandison
Tanzania Journal of Science
This study examined the effects of storage conditions (in particular temperature and media composition) and changes in composition of each milk fraction, and of individual components on lactoperoxidase (LP) activity. The enzyme demonstrated a pulsing characteristic especially in samples stored at 5 °C, however, temperature and media composition did not have great effects on the pulsing behaviour of the enzyme. The results also indicated small but statistically significant variations (P ≤ 0.05) in LP activity between whole milk (control) and acid whey, rennet whey and cream and non-significant variations (P > 0.05) between the control and skimmed milk, and between skimmed …
Current Epidemiological Assessment Of Plasmodium Falciparum And Helminth Co-Infections In Children After A Decade Of Implementation Of Control Programs In Morogoro Region, Tanzania, Christopher Kisiringyo, Winifrida Kidima
Current Epidemiological Assessment Of Plasmodium Falciparum And Helminth Co-Infections In Children After A Decade Of Implementation Of Control Programs In Morogoro Region, Tanzania, Christopher Kisiringyo, Winifrida Kidima
Tanzania Journal of Science
A school based cross-sectional study was conducted from July to November 2018 to assess the burden of asymptomatic Plasmodium falciparum, Schistosoma and soil transmitted helminth (STH) infections in Mvomero. A total of 374 children (age range = 5–16 years, mean age = 11.3 years) were recruited from five primary schools. Prevalence of asymptomatic P. falciparum infections were 29.9%, S. haematobium 49.7%, hookworm 20.3%, Ascaris lumbricoides 12.6%, Taenia saginata 0.5% and S. mansoni 0.3%. Malaria parasite density increased with increasing children age (r = 0.99). Only 6.5% (12/186) of S. haematobium infected children were presented with heavy infections, whereas all STH-positive …
Effects Of 15 Local Medicinal Plant Species On Protein Tyrosine Phosphatase 1b And Dipeptidyl Peptidase 1v Activity As Herbal Antidiabetic Type 2 Remedies, Pamhidzai Dzomba, Chidavayenzi Tinevimbo
Effects Of 15 Local Medicinal Plant Species On Protein Tyrosine Phosphatase 1b And Dipeptidyl Peptidase 1v Activity As Herbal Antidiabetic Type 2 Remedies, Pamhidzai Dzomba, Chidavayenzi Tinevimbo
Tanzania Journal of Science
This study aimed at investigating plant species that are used locally in Zimbabwe to manage diabetes type 2 and their respective modes of action using in vitro studies. The plants for this study were identified by ethnobotanical studies and their respective antidiabetic potentials were evaluated using protein tyrosine phosphatase 1B (PTP 1B) and dipeptidyl peptidase IV (DPP IV) inhibition assays. Out of the 15 plant species used to manage diabetes in traditional practices, 9 inhibited PTP 1B with half maximal inhibitory concentrations (IC50) ranging from 0.03 ± 0.00 to 61.31 ± 0.70 µg/mL. The mechanism of inhibition deduced from Lineweaver-Burk …
Extraction, Derivatization, Characterization And Antifungal Investigation Of Limonene From Citrus Sinensis Peels, Ita Uwidia, Bodunde Owolabi, Richard Okafor
Extraction, Derivatization, Characterization And Antifungal Investigation Of Limonene From Citrus Sinensis Peels, Ita Uwidia, Bodunde Owolabi, Richard Okafor
Tanzania Journal of Science
Limonene, a cyclic monoterpene is the main component in citrus oils. Oranges (Citrus sinensis) were sourced from a local market, peeled and the peels collected for this study. The orange peels were distilled using steam distillation to obtain the oil. The oil obtained was then distilled to obtain a pure colourless form of limonene (95%). The limonene (2 ml) was dissolved in dry chloroform (25 ml) and freshly distilled hydroiodic acid (57%; boiling point 127 °C) to give the derivative iodo-limonene (1.4 g; 30% yield). Another reaction of epoxidation of limonene was carried out by reacting limonene with hydrogen peroxide …