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2023

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Articles 1561 - 1590 of 1823

Full-Text Articles in Biology

Secondary Analysis Of Chip-Seq Dataset And Genomic Interactions Of Icer, Karem Rivera Jan 2023

Secondary Analysis Of Chip-Seq Dataset And Genomic Interactions Of Icer, Karem Rivera

Theses, Dissertations and Culminating Projects

The Inducible cyclic AMP (cAMP) Early Repressor (ICER) is an endogenous transcriptional repressor of the cAMP-mediated signaling gene transcription pathway and belongs to the CRE-binding protein (CREB)/CRE modulator (CREM) gene family. ICER is associated to many functions and biological processes in the immune system, brain, regulation of spermatogenesis, circadian control of transcription, apoptosis and metabolic functions, and of particular interest, has been shown to act like a tumor suppressor. Recent findings from our laboratory suggest that ICER might have a role in DNA repair, but further experiments need to be performed. In this research, we aimed to elucidate the function …

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Assessing The Relationship Between Binding Kinetics And Subcellular Protection Of Ribosomes By Single-Domain Antibodies, Mara Bureau Jan 2023

Assessing The Relationship Between Binding Kinetics And Subcellular Protection Of Ribosomes By Single-Domain Antibodies, Mara Bureau

Legacy Theses & Dissertations (2009 - 2024)

Assessing the ability of VHHs to protect ribosomes from the depurination activity of Ricin toxin’s(RT) enzymatic subunit, RTA, can provide insights regarding binding placement, epitopes of interest and role of affinity in neutralization is critical for the development of anti-toxin countermeasures. Determining the level of correlation between binding strength, binding location and elicited protection can be useful for future and ongoing research. Ricin is easily manufactured and considered one of the most toxic biological agents known. Without an approved vaccine, continued research to design and optimize therapeutic countermeasures is essential. Over the past decade single-domain antibodies (VHHs) have been recognized …

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Olfaction And Puberty : The Study Of The Development And Migration Of The Gnrh-1ns And Their Migratory Partners The Olfactory Unsheathing Cells, Ed Zandro Moina Taroc Jan 2023

Olfaction And Puberty : The Study Of The Development And Migration Of The Gnrh-1ns And Their Migratory Partners The Olfactory Unsheathing Cells, Ed Zandro Moina Taroc

Legacy Theses & Dissertations (2009 - 2024)

Sexual development and puberty are two key developmental processes that are crucial for the propagation and evolution of species. The hormone Gonadotropin releasing hormone-1 (GnRH-1) is a key hormone in regulating both processes by controlling the hormonal Hypothalamic-Pituitary-Gonadal axis in the release of sex hormones (Testosterone, Estrogen, Progesterone) at the correct developmental time points initiate puberty and progress sexual development. A subset of hypothalamic neurons known as the GnRH-1 neurons (GnRH-1ns) release GnRH-1 in a pulsatile fashion during embryonic and post-natal development to specifically regulate these processes. The GnRH-1ns are an interesting group of neurons because they are formed in …

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Endothelial And Stromal Cell Contributions To Salivary Gland Injury And Repair, Amber Altrieth Jan 2023

Endothelial And Stromal Cell Contributions To Salivary Gland Injury And Repair, Amber Altrieth

Legacy Theses & Dissertations (2009 - 2024)

Injury and disease can contribute to excess accumulation of extracellular matrix, which if persistent, results in fibrosis, impeding proper organ function. The salivary gland can develop fibrosis following irradiation treatment for cancer therapy, Sjögren’s Disease, and other causes; however, it is unclear which stromal cells and signals participate in injury responses and disease progression and which cells may be important for restoring proper organ function. Two stromal populations that are implicated in injury and repair are the endothelial cells, lining the inner surface of blood vessels, and pericytes, that wrap around the vessels. One stromal pericyte population, expressing the transcription …

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Regulatory Mechanisms In The Drosophila Germline, Shane Breznak Jan 2023

Regulatory Mechanisms In The Drosophila Germline, Shane Breznak

Legacy Theses & Dissertations (2009 - 2024)

To launch the next generation, all sexually reproducing animals must undergo the process of producing mature eggs and sperm. This process is known as gametogenesis. During gametogenesis key developmental checkpoints are met to ensure proper egg and sperm production. Model organisms, such as Drosophila melanogaster, have been used to study gametogenesis to gain insight into the conserved mechanisms that can be attributed to human infertility and disease due to the availability of genetic tools, quick life cycle and the conservation of regulatory mechanisms. During Drosophila oogenesis there are many key developmental transitions that must be completed to produce a fully …

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Distribution Patterns And Factors Influencing Relative Abundance Of The Alligator Snapping Turtle (Macrochelys Temminckii) In Mississippi, Luke Pearson, Lucas Haralson, Gabrielle Berry, Grover J. Brown, Carl Qualls Jan 2023

Distribution Patterns And Factors Influencing Relative Abundance Of The Alligator Snapping Turtle (Macrochelys Temminckii) In Mississippi, Luke Pearson, Lucas Haralson, Gabrielle Berry, Grover J. Brown, Carl Qualls

Research, Publications & Creative Work

Macrochelys temminckii (Alligator Snapping Turtle) was recently proposed as a threatened species under the US Endangered Species Act due to current and projected future declining populations range wide. Despite a presumed statewide distribution in Mississippi, the Alligator Snapping Turtle had been documented in only 32 of 82 counties between 1857 and 2012, thus leaving a substantial gap in our knowledge of this species’ distribution. Therefore, we collected credible records from museums, literature, and the general public, as well as directly assessed the current distribution and relative abundance of the Alligator Snapping Turtle in all major river systems (i.e., Pascagoula, Pearl, …

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Gross Ecosystem Product Accounting Of A Globally Important Agricultural Heritage System: The Longxian Rice–Fish Symbiotic System, Jianfang Liu, Qian Zhang, Qianyi Wang, Yaoping Lv, Yingqi Tang Jan 2023

Gross Ecosystem Product Accounting Of A Globally Important Agricultural Heritage System: The Longxian Rice–Fish Symbiotic System, Jianfang Liu, Qian Zhang, Qianyi Wang, Yaoping Lv, Yingqi Tang

Research, Publications & Creative Work

The Rice–Fish Symbiotic System in the Longxian village is the first Globally Important Agricultural Heritage System (GIAHS) in Asia. This paper examined the value transformation mechanism of the Longxian Rice–Fish Symbiotic System from the micro perspective of material cycle and energy flow and quantified its economic value using the gross ecosystem product (GEP). Using the InVEST model and ArcGIS tools, the GEP was estimated to be approximately CNY 116.51 million (approx. CNY 252,624 per hectare per year). The ecosystem regulating service value occupied more than 80% of the GEP. Within the regulating ecosystem services, the climate regulation value was the …

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The Impact Of Nutrient Depletion On The Effect Of Hhq On Emiliania Huxleyi, Marley Gonsalves Jan 2023

The Impact Of Nutrient Depletion On The Effect Of Hhq On Emiliania Huxleyi, Marley Gonsalves

Honors Theses and Capstones

Emiliania huxleyi is a ecologically important, bloom-forming coccolithophore. HHQ is a bacteria compound that causes cell stasis in E. huxleyi that can lead to bloom termination. This study analyzed the role that nutrient depletion plays in this relationship. Results show that nitrogen depletion protects cells from the effects of HHQ, affecting bloom dynamics.

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Investigation Of The Function Of Protein Acyl Transferases Using Crispr-Cas9 To Create Null Mutants, Claire E. Christopher Jan 2023

Investigation Of The Function Of Protein Acyl Transferases Using Crispr-Cas9 To Create Null Mutants, Claire E. Christopher

Honors Theses and Capstones

24 Protein Acyl Transferases (PATs) have been identified in the model organism Arabidopsis thaliana. Despite knowing the enzymatic function of these genes (palmitoylation), the specific subcellular pathways, protein targets, and cellular activities of these proteins remain unknown. To investigate the pathways that PAT genes are involved in, deletion mutations were created in several genes and the phenotype of the organisms carrying homozygous mutations was observed. To introduce mutations, the CRISPR/Cas9 system was inserted into the plant’s genome using Agrobacterium tumefaciens to cause deletions in PAT genes of interest. To date, no CRISPR-induced pat mutants have a noticeable phenotype. These …

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Potential Anti-Alzheimer Properties Of Mogrosides In Vitamin B12-Deficient Caenorhabditis Elegans, Denia Cai Shi, Chunlin Long, Ella Vardeman, Edward J. Kennelly, Michael A. Lawton, Rong Di Jan 2023

Potential Anti-Alzheimer Properties Of Mogrosides In Vitamin B12-Deficient Caenorhabditis Elegans, Denia Cai Shi, Chunlin Long, Ella Vardeman, Edward J. Kennelly, Michael A. Lawton, Rong Di

Publications and Research

Vitamin B12 deficiency can lead to oxidative stress, which is known to be involved in neurodegenerative diseases such as Alzheimer’s disease (AD). Mogrosides are plant-derived triterpene glycosides that exhibit anti-inflammatory and antioxidant activity in animal cell lines and mouse models. Since amyloid-β toxicity is known to cause oxidative stress and damage to brain cells, we hypothesized that mogrosides may have a protective effect against AD. In this study, we investigated the potential anti-AD effect of mogrosides in vitamin B12-deficient wild-type N2 and in transgenic CL2355 Caenorhabditis elegans expressing amyloid-β peptide. Our data indicated that mogrosides have a beneficial effect on …

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Diversity Of Antimicrobial Peptides In Silkworm, Pooja Makwana, Kamidi Rahul, Katsuhiko Ito, Bindu Subhadra Jan 2023

Diversity Of Antimicrobial Peptides In Silkworm, Pooja Makwana, Kamidi Rahul, Katsuhiko Ito, Bindu Subhadra

Faculty Publications - Biological Sciences

Antimicrobial resistance is a phenomenon that the present-day world is witnessing that poses a serious threat to global health. The decline in the development of novel therapeutics over the last couple of decades has exacerbated the situation further. In this scenario, the pursuit of new alternative therapeutics to commonly used antibiotics has gained predominance amongst researchers across the world. Antimicrobial peptides (AMPs) from natural sources have drawn significant interest in the recent years as promising pharmacological substitutes over the conventional antibiotics. The most notable advantage of AMPs is that microorganisms cannot develop resistance to them. Insects represent one of the …

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Microdebris Abundance, Distribution, And Ingestion By Sargassum-Associated Juvenile Fishes In The Gulf Of Mexico, Olivia L. Lestrade, Frank Hernandez Jan 2023

Microdebris Abundance, Distribution, And Ingestion By Sargassum-Associated Juvenile Fishes In The Gulf Of Mexico, Olivia L. Lestrade, Frank Hernandez

Gulf and Caribbean Research

Holopelagic Sargassum is a critical nursery habitat for the early life stages of many marine fishes, including several federally managed species in the United States and Caribbean. Sargassum is often aggregated along surface convergence features where microdebris (synthetic, semi—synthetic, and naturally—derived particles size) have also been found in relatively high concentrations. In this study, we collected microdebris from Sargassum and adjacent open water habitats (in 2018), and juvenile fishes from Sargassum (in 2017 and 2018) in the northern Gulf of Mexico to quantify habitat—specific microdebris concentrations and the degree to which Sargassum—associated juvenile fishes ingest microdebris. Microdebris concentrations within …

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Warm Land Surface Temperatures And Eastern Asian Homo, Robert Patalano, Hong Yang Jan 2023

Warm Land Surface Temperatures And Eastern Asian Homo, Robert Patalano, Hong Yang

Biological and Biomedical Sciences Department Faculty Journal Articles

Climate change and hominin evolution are inextricably linked. Pleistocene climate variability, for example, is thought to have had major influences on hominin morphology, brain size, and diversity. However, clear cause-and-effect relationships between specific climatic events and major evolutionary occurrences are difficult to establish due to temporal and spatial gaps in paleoclimatic, paleoenvironmental, and archaeological records. A new branched GDGT paleotemperature record from the Lantian Basin of Central China (Lu et al., 2022), a location known for the earliest hominin presence in East Asia, illustrates warm land surface temperatures over a two-million-year period between 2.6 and 0.6 Ma, a critical time …

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Mycorrhizal Feedbacks Influence Global Forest Structure And Diversity, Camille S. Delavaux, Joseph A. Lamanna, Jonathan A. Myers, Richard P. Phillips Jan 2023

Mycorrhizal Feedbacks Influence Global Forest Structure And Diversity, Camille S. Delavaux, Joseph A. Lamanna, Jonathan A. Myers, Richard P. Phillips

Biological Sciences Faculty Research and Publications

One mechanism proposed to explain high species diversity in tropical systems is strong negative conspecific density dependence (CDD), which reduces recruitment of juveniles in proximity to conspecific adult plants. Although evidence shows that plant-specific soil pathogens can drive negative CDD, trees also form key mutualisms with mycorrhizal fungi, which may counteract these effects. Across 43 large-scale forest plots worldwide, we tested whether ectomycorrhizal tree species exhibit weaker negative CDD than arbuscular mycorrhizal tree species. We further tested for conmycorrhizal density dependence (CMDD) to test for benefit from shared mutualists. We found that the strength of CDD varies systematically with mycorrhizal …

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The Role Of Herbal Medicines In Central American Indigenous Communities; Improving Accessibility To Type 2 Diabetes Mellitus Treatment, Sarai Ortega Jan 2023

The Role Of Herbal Medicines In Central American Indigenous Communities; Improving Accessibility To Type 2 Diabetes Mellitus Treatment, Sarai Ortega

CMC Senior Theses

Indigenous communities in Central America have used various plant medications to treat illnesses and diseases for centuries. Clinicians must consider improving traditional healthcare methods that are intrinsic to indigenous communities in order to increase access to effective treatments, particularly for diseases that these communities are more at risk for. This work aims to propose a method to identify whether traditional preparations of five plants (Anacardium occidentale L., Hamelia patens Jacq., Momordica charantia L, Neurolaena lobota L. R. Br. Ex Cass., and Tecoma stans L. juss. ex Kunth) can reduce blood glucose levels in rats with type two diabetes. Additionally, …

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Movement As Medicine: Dance/Movement Therapy For Individuals With Autism, Parkinson’S Disease, And Cancer, Alessia Zanobini Jan 2023

Movement As Medicine: Dance/Movement Therapy For Individuals With Autism, Parkinson’S Disease, And Cancer, Alessia Zanobini

CMC Senior Theses

Dance/movement therapy (D/MT) is the psychotherapeutic use of expressive, creative movement to support holistic well-being. D/MT views the human being as a single body-mind unit and movement as a manifestation of life experiences. While typically practiced as a mental health intervention, D/MT can be adapted for a variety of populations. This thesis evaluates scientific data for the non-traditional use of D/MT for three conditions: autism, Parkinson’s disease, and cancer. For individuals on the autism spectrum, D/MT can strengthen attunement skills, provide creative communication outlets, and relieve harmful physical manifestations of autism. For individuals with Parkinson’s disease, D/MT can simultaneously ease …

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Effects Of Male Attractiveness On Prostaglandin E2 Production Levels, Kyra Cousins Jan 2023

Effects Of Male Attractiveness On Prostaglandin E2 Production Levels, Kyra Cousins

CMC Senior Theses

Sexual conflict or sexual antagonism can encourage co-evolution between males and females of a given species. In house crickets (Acheta domesticus), unattractive (smaller) and attractive (larger) males seem to use differential allocation of prostaglandin E2 in their spermatophore to pursue different propagation strategies in influencing female oviposition. This study aims to determine the means by which attractive and less attractive males press their reproductive advantage by focusing on prostaglandin E2. To test the hypothesis that the difference in prostaglandin E2 concentration is essential for female reproductive manipulation, spermatophores were retrieved from 21 pairs of mated …

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Evolutionary History And Adaptation To Salinity In American Alligators, John Konvalina Jan 2023

Evolutionary History And Adaptation To Salinity In American Alligators, John Konvalina

Electronic Theses and Dissertations, 2020-2023

Stressful environments can commonly be found at the edge of a species range and may be a driver for adaption in suboptimal environments. Furthermore, the edge of a species' range can expand and contract over time, resulting in multiple independent invasions of the same stressful habitat. Elucidating population genetic structure and demographic history can aid in determining the which geologic factors impact range distributions and when climatic changes occurred driving genetic patterns observed in contemporary populations. Moreover, populations at the edge of the species range may adapt to the stressful environments that occur at the range edge and exhibit genetic …

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Mechanical Devices For Census And Detection Of Off-Host Larval Ticks (Acari: Ixodidae), Donald B. Thomas, Holly D. Gaff, Brenda Leal-Galvan Jan 2023

Mechanical Devices For Census And Detection Of Off-Host Larval Ticks (Acari: Ixodidae), Donald B. Thomas, Holly D. Gaff, Brenda Leal-Galvan

Biological Sciences Faculty Publications

Standard off-host tick census techniques are generally inefficient for larval stages. Also, such techniques expose the investigator to environmental hazards including tick bites. Mechanical devices are an option which were tested under field conditions for proof of concept and in side-by-side comparison to the standard techniques. The tick-vac collected more ticks than the legging technique, but with lower frequency of positive detections. It may have utility for sampling small areas, such as weedy corrals suspected of harboring ticks. Different configurations of tick-bots, robotic vehicles with flags, depended on intensive operator control to avoid obstacles, limiting operation to line of sight. …

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The Coral Bleaching Automated Stress System (Cbass): A Low Cost, Portable System For Standardized Empirical Assessments Of Coral Thermal Limits, Nicolas R. Evensen, Katherine E. Parker, Thomas A. Oliver, Stephen R. Palumbi, Cheryl A. Logan, James S. Ryan, Courtney N. Klepac, Gabriela Perna, Mark E. Warner, Christian R. Voolstra, Daniel J. Barshis Jan 2023

The Coral Bleaching Automated Stress System (Cbass): A Low Cost, Portable System For Standardized Empirical Assessments Of Coral Thermal Limits, Nicolas R. Evensen, Katherine E. Parker, Thomas A. Oliver, Stephen R. Palumbi, Cheryl A. Logan, James S. Ryan, Courtney N. Klepac, Gabriela Perna, Mark E. Warner, Christian R. Voolstra, Daniel J. Barshis

Biological Sciences Faculty Publications

Ocean warming is increasingly affecting marine ecosystems across the globe. Reef-building corals are particularly affected by warming, with mass bleaching events increasing in frequency and leading to widespread coral mortality. Yet, some corals can resist or recover from bleaching better than others. Such variability in thermal resilience could be critical to reef persistence; however, the scientific community lacks standardized diagnostic approaches to rapidly and comparatively assess coral thermal vulnerability prior to bleaching events. We present the Coral Bleaching Automated Stress System (CBASS) as a low-cost, open-source, field-portable experimental system for rapid empirical assessment of coral thermal thresholds using standardized temperature …

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Variation In Establishment Success For American Mistletoe [Phoradendron Leucarpum (Raf.) Reveal & M.C. Johnst. (Viscaceae)] Appears Most Likely To Predict Its Distribution In Virginia And North Carolina, United States, Nicholas P. Flanders, Christopher P. Randle, Eric L. Walters, Lytton J. Musselman Jan 2023

Variation In Establishment Success For American Mistletoe [Phoradendron Leucarpum (Raf.) Reveal & M.C. Johnst. (Viscaceae)] Appears Most Likely To Predict Its Distribution In Virginia And North Carolina, United States, Nicholas P. Flanders, Christopher P. Randle, Eric L. Walters, Lytton J. Musselman

Biological Sciences Faculty Publications

Dispersal limitation and variation in habitat suitability may determine an association of American mistletoe [Phoradendron leucarpum (Raf.) Reveal & M.C. Johnst. (Viscaceae)] with forested wetlands in Virginia and North Carolina, United States. Here, we first tested the alternative hypothesis that variation in host availability drives this habitat relationship. We used a generalized linear model to show a positive effect of forested wetland habitat on American mistletoe occurrence after accounting for both variation in host availability and differences among regions in host use. We then used seed sowing experiments to quantify how light availability and flood regime determine the viability …

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Admixpipe V3: Facilitating Population Structure Delimitation From Snp Data, Steven M. Mussmann, Marlis R. Douglas, Tyler Chafin, Michael E. Douglas Jan 2023

Admixpipe V3: Facilitating Population Structure Delimitation From Snp Data, Steven M. Mussmann, Marlis R. Douglas, Tyler Chafin, Michael E. Douglas

Biological Sciences Faculty Publications and Presentations

Quantifying genetic clusters (=populations) from genotypic data is a fundamental, but non-trivial task for population geneticists that is compounded by: hierarchical population structure, diverse analytical methods, and complex software dependencies. AdmixPipe v3 ameliorates many of these issues in a single bioinformatic pipeline that facilitates all facets of population structure analysis by integrating outputs generated by several popular packages (i.e. CLUMPAK, EvalAdmix). The pipeline interfaces disparate software packages to parse Admixture outputs and conduct EvalAdmix analyses in the context of multimodal population structure results identified by CLUMPAK. We further streamline these tasks by packaging AdmixPipe v3 within a Docker container to …

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Pancreatic Ductal Adenocarcinoma And New Treatments In Development, Melissa J. Moisan Jan 2023

Pancreatic Ductal Adenocarcinoma And New Treatments In Development, Melissa J. Moisan

Biology and Microbiology Graduate Students Plan B Research Projects

Pancreatic ductal adenocarcinoma (PDAC) is the most frequently mutated (95%) 5exocrine pancreatic cancers. Patients with PDAC are also the least likely to survive more than 5 years with only 8% overall survivability. The median survival for patients with distant metastasis is less than one year. Most pancreatic ductal adenocarcinoma occurs in the pancreatic head, and the remainder can be found within the body (5% to 15%) or tail (10% to 15%) (14). This extremely aggressive cancer has an increasingly large metastatic dissemination rate to surrounding organs such as the liver, lung, and peritoneum, or can be seen as distant metastases …

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The Evaluation Of The Efficacy And Safety Of Different Methods Of Myopia Control, Chaya Feuchtwanger Jan 2023

The Evaluation Of The Efficacy And Safety Of Different Methods Of Myopia Control, Chaya Feuchtwanger

The Science Journal of the Lander College of Arts and Sciences

Myopia is the leading cause of preventable blindness in East Asia and has a rising global prevalence. If no treatment is done to curb myopic progression, the eye will continue to grow leading to high refractive errors. A higher prescription leads to an increased risk of developing sight-threatening diseases that can lead to irreversible blindness later in life. The discovery of a treatment that slows or even stops myopia from progressing is increasingly important with many studies being conducted worldwide. Currently, the most effective forms of myopia control are atropine eye drops and specialty contact lenses, with new studies exploring …

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Epilepsy And Treatment Resistance, Eva Kowalsky Jan 2023

Epilepsy And Treatment Resistance, Eva Kowalsky

The Science Journal of the Lander College of Arts and Sciences

Epilepsy is one of the most common debilitating neurological conditions. Individuals with epilepsy experience frequent seizures. Seizures are caused by hyperexcitable and hyper-synchronized neurons. Anti-seizure medications typically work to normalize the electrical activity in the brain. Many epileptic disorders are caused by genetic mutations, most of which cause mutations in ion channel mechanics. 30% of individuals with epilepsy do not respond to classic anti-seizure medications. A combination of factors typically contributes to treatment resistance. Individuals with drug-resistant epilepsy must turn to novel approaches for seizure relief. These approaches include following a ketogenic diet, using CBD products, utilizing a neurostimulator device, …

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The Effects Of Nausea And Vomiting On Mother And Child, Mayane Bensoussan Jan 2023

The Effects Of Nausea And Vomiting On Mother And Child, Mayane Bensoussan

The Science Journal of the Lander College of Arts and Sciences

Nausea and vomiting are common side effects that can occur during pregnancy. On one hand, it can lead to its severe form called hyperemesis gravidarum, which can lead to hospitalization for electrolyte imbalances, dehydration, muscle weakness, or arrhythmias. On the other hand, nausea and vomiting may be an indication of a statistically healthier fetus. Benefits of maternal nausea and emesis to the developing fetus include improved neural development, decreased risk for congenital heart defects, and decreased incidence of miscarriages. Additionally, benefits to the mother include decreased risk for lung, cervical, and rectal cancer. The mothers also had an overall decreased …

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Effects Of Microdosing With Psilocybin Mushrooms, Chavivah Davis Jan 2023

Effects Of Microdosing With Psilocybin Mushrooms, Chavivah Davis

The Science Journal of the Lander College of Arts and Sciences

Microdosing with psilocybin, a psychoactive compound found in certain species of mushrooms, has gained popularity in recent years as a means of enhancing mood, cognition, and creativity without inducing the full-blown psychedelic experience. There are many potential benefits associated with microdosing with psilocybin. Although studies do show many positive effects of microdosing with psilocybin, long-term research is required to make a conclusive statement regarding this topic. Furthermore, there are risks and concerns involved that need to be considered, including the illegality of psilocybin and the lack of research. This paper will review the available literature on microdosing with psilocybin. It …

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Epinephrine And Cardiac Arrest: The Catch-22, Shaina Friedman Jan 2023

Epinephrine And Cardiac Arrest: The Catch-22, Shaina Friedman

The Science Journal of the Lander College of Arts and Sciences

Epinephrine has been a standard of care treatment for cardiac arrest for the last century; however, the use of epinephrine began without a significant amount of research. In recent years, many have started to question whether epinephrine is an appropriate treatment for cardiac arrest. While epinephrine causes vasoconstriction of the blood vessels and directs much-needed blood flow to the heart, it has also been shown to harm the microvessels of the brain, causing ischemia and neurological damage. Many trials, studies, and surveys were conducted to determine the correct course of action involving the use of epinephrine during cardiac arrest. Additional …

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The Impact Of Maternal Health On Breastfeeding Duration, Yael Weinberg Jan 2023

The Impact Of Maternal Health On Breastfeeding Duration, Yael Weinberg

The Science Journal of the Lander College of Arts and Sciences

The mechanism of breastfeeding is a complex biological process beginning with hormone production from the pituitary gland and ending with the ejection of milk from the breasts. Mothers are recommended to breastfeed exclusively for six months and then continue for another six with the addition of solid food. However, despite the countless health benefits associated with lengthened breastfeeding for both mother and infant, many women dismiss this recommendation. This paper aims to research the aspects of maternal health that can derail the recommended duration of breastfeeding, focusing on emotional health, nutritional intake, and various diseases or surgeries. It is found …

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Do The Benefits Of Growth Hormone Outweigh The Risks?, Michael D. Goodstein Jan 2023

Do The Benefits Of Growth Hormone Outweigh The Risks?, Michael D. Goodstein

The Science Journal of the Lander College of Arts and Sciences

Growth hormone treatment was introduced in the 1950s to confront growth hormone deficiency and metabolic irregularities. In 2003, however, the FDA approved growth hormone treatment for patients with abnormal growth rates unlinked to growth hormone deficiency. The treatment has become largely available to the general public, making the safety of growth hormone treatment an extremely important subject. This paper clarifies the benefits and efficacy of growth hormone treatment and analyzes the potential associated risks, including cancer and diabetes.

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