Biology Commons^™

What Does Soil-Transmitted Helminth Elimination Look Like? Results From A Targeted Molecular Detection Survey In Japan, Mitsuko Hasegawa, Nils Pilotte, Mihoko Kikuchi, Arianna R. Means, Marina Papaiakovou, Andrew M. Gonzalez, Jacqueline R.M.A. Maasch, Hiroshi Ikuno, Toshihiko Sunahara, Kristjana H. Ásbjörnsdóttir, Judd L. Walson, Steven A. Williams, Shinjiro Hamano

Biological Sciences: Faculty Publications

Background: Japan is one of the few countries believed to have eliminated soil-transmitted helminths (STHs). In 1949, the national prevalence of Ascaris lumbricoides was 62.9%, which decreased to 0.6% in 1973 due to improvements in infrastructure, socioeconomic status, and the implementation of national STH control measures. The Parasitosis Prevention Law ended in 1994 and population-level screening ceased in Japan; therefore, current transmission status of STH in Japan is not well characterized. Sporadic cases of STH infections continue to be reported, raising the possibility of a larger-scale recrudescence of STH infections. Given that traditional microscopic detection methods are not sensitive to …

What Does Soil-Transmitted Helminth Elimination Look Like? Results From A Targeted Molecular Detection Survey In Japan, Mitsuko Hasegawa, Nils Pilotte, Mihoko Kikuchi, Arianna R. Means, Marina Papaiakovou, Andrew M. Gonzalez, Jacqueline R.M.A. Maasch, Hiroshi Ikuno, Toshihiko Sunahara, Kristjana H. Ásbjörnsdóttir, Judd L. Walson, Steven A. Williams, Shinjiro Hamano

Biological Sciences: Faculty Publications

Background: Japan is one of the few countries believed to have eliminated soil-transmitted helminths (STHs). In 1949, the national prevalence of Ascaris lumbricoides was 62.9%, which decreased to 0.6% in 1973 due to improvements in infrastructure, socioeconomic status, and the implementation of national STH control measures. The Parasitosis Prevention Law ended in 1994 and population-level screening ceased in Japan; therefore, current transmission status of STH in Japan is not well characterized. Sporadic cases of STH infections continue to be reported, raising the possibility of a larger-scale recrudescence of STH infections. Given that traditional microscopic detection methods are not sensitive to …

Building Bodies, Building Minds, Lis Regula

Learning Teaching Forum

Kennedy Union 211

Majors level Human Anatomy has long been taught as a gatekeeping class for medical schools of graduate schools, and has been highly professionalized due to this. It has also been constructed historically in a very hierarchical paradigm that has multiple oppressions supporting both the study of anatomy and the anatomy classroom. Besides these social issues around anatomy, there are the pedagogical issues of treating this material as something to just memorize and not understand that can cause problems for a student of anatomy. Disrupting these processes can be a very powerful force for anti-racism, anti-sexism, and hopefully …

The Role Of Demographic History And Selection In Shaping Genetic Diversity Of The Galápagos Penguin (Spheniscus Mendiculus), Gabriella Arauco-Shapiro, Katelyn I. Schumacher, Dee Boersma, Juan L. Bouzat

Biological Sciences Faculty Publications

Although many studies have documented the effects of demographic bottlenecks on the genetic diversity of natural populations, there is conflicting evidence of the roles that genetic drift and selection may play in driving changes in genetic variation at adaptive loci. We analyzed genetic variation at microsatellite and mitochondrial loci in conjunction with an adaptive MHC class II locus in the Galápagos penguin (Spheniscus mendiculus), a species that has undergone serial demographic bottlenecks associated with El Niño events through its evolutionary history. We compared levels of variation in the Galápagos penguin to those of its congener, the Magellanic penguin (Spheniscus magellanicus), …

A&P Workshop Summary—Uniting Anatomy And Physiology Through Case Studies, Angela Horner, Stuart Sumida, Tomasz Owercowicz

Q2S Enhancing Pedagogy

Introducing problem-solving based methods of pedagogy is one approach to engage students early in their careers with developing analytic and diagnostic skills. PBL approaches in anatomy and medical teaching are a logical extension of clinical case studies, wherein an example of a pathology or clinical procedure is provided, and students must ascertain the anatomical and/or physiological basis for it. Students report a deeper understanding of material presented in clinical case studies, as the ‘real world’ relevance and importance is immediately clear (Cliff and Wright, 1996).

Complete Genome Sequences Of Streptococcus Mitis Strains Isolated From The Oral Cavity And Urogenital Tract Of A Woman And Her Male Sexual Partner, Carine R. Mores, Travis K. Price, Bridget Brassil, Catherine Putonti, Alan J. Wolfe

Bioinformatics Faculty Publications

Streptococcus mitis is a member of the mitis group of the genus Streptococcus, which includes commensal species of the oral cavity and upper respiratory tract. Here, we report 39 complete genome sequences of S. mitis strains isolated from the oral cavity and urogenital tract of a woman and her male sexual partner.

Analyzing The Effect On Ligand Sensitivity For Xenopus Tropicalis Mc1r, Mc3r, Mc4r, And Mc5r As A Result Of Coexpression With Gallus Gallus Mrap1 In Chinese Hamster Ovary Cells, Avery Niemann, Robert Dores

DU Undergraduate Research Journal Archive

Some melanocortin receptors and the accessory protein MRAP1 have been found to interact in novel ways when co-expressed in the same cells following stimulation with either ACTH (1-24) or αMSH. These interactions have been seen for mammalian, bird, and some bony fish melanocortin receptors. Such analysis has not been done yet on the amphibian melanocortin receptors, MC1R, MC3R, MC4R, and MC5R. To this end, this study was done on the effects regarding ligand sensitivity for ACTH (1-24) and αMSH, when the MC1R, MC3R, MC4R, and MC5R paralogs of the amphibian, Xenopus tropicalis were expressed in Chinese Hamster Ovary cells either …

Draft Genome Sequences Of Two Pseudomonas Aeruginosa Isolates From The Female Urogenital Tract, Genevieve Johnson, Carine R. Mores, Alan J. Wolfe, Catherine Putonti

Bioinformatics Faculty Publications

Pseudomonas aeruginosa is a Gram-negative bacterium that has the ability to survive in and readily adapt to a variety of environmental conditions. Here, we report 2 genome sequences of P. aeruginosa strains, UMB1046 and UMB5686, isolated from the female urogenital tract.

Tanaidacea– Forty Years Of Scholarship, Version 3.0, Gary Anderson

Tanaidacea - Recent Scholarship

No abstract provided.

Kimberlyn Williams Cd Summer 2019, Kimberlyn Williams

Innovative Course Redesign Grant Reports

No abstract provided.

Investigating The Patterns And Mechanisms Of Alternative Splicing Of Cav1.3 In The Mouse., Samuel Sabzanov

Theses and Dissertations

AL-type voltage-gated calcium channel Cav1.3 contains a pore-forming α-1 subunit that is encoded by Cacna1d, a gene which has been shown to undergo alternative splicing (AS). Mutations in CACNA1D have been associated with neurological diseases such as spontaneous seizure disorder and epilepsy. Previous studies have shown that AS of the C-terminus of Cav1.3 results in a truncated variant of exon 42 (E42) that, when compared to the full-length exon, lowers the voltage threshold needed to activate the calcium channel. Therefore, AS of the a1-subunit can modulate the physiological properties of Cav1.3. As a lower voltage threshold of calcium channels increases …

Does Preimplantation Genetic Testing Increase The Risk Of Adverse Clinical Outcomes?, Robyn Weiss

The Science Journal of the Lander College of Arts and Sciences

Before 1990, options were limited for couples who were at risk for transmitting a genetic disease or a structural chromosomal abnormality to their children. Couples traditionally underwent invasive procedures such as amniocentesis and chorionic villus sampling, after which termination was offered if the fetus was found to be affected. Many couples chose not to have children at all. Since then, technological advances have allowed preimplantation genetic testing (PGT) to be offered to these couples. Couples who choose PGT undergo in-vitro fertilization (IVF) with intracytoplasmic sperm injection (ICSI), where the oocyte is injected by a single sperm and is then implanted …

The Undergraduate Student’S Guide To Geometric Morphometrics, Erika Crispo

Open Educational Resources

Embarking on a new research endeavor can be a daunting task. User guides, books, and published articles are written for an audience that already has some background experience in the field. Undergraduate students like you, who are at the very beginning of their research careers, often struggle to make sense of these documents. Furthermore, students like you often attempt to do so while balancing heavy course loads. Thus, I have written this document to help ease the burden so that you have more time to ponder the interesting scientific questions instead of digging through pages upon pages of documentation. I …

A Mafg-Lncrna Axis Links Systemic Nutrient Abundance To Hepatic Glucose Metabolism, Jenny Link, Martha Pradas-Juni, Nils R. Hansmeier, Elena Schmidt, Bjørk Ditlev Larsen, Paul Klemm, Nicola Meola, Hande Topel, Rute Loureiro, Ines Dhaouadi, Christoph A. Kiefer, Robin Schwarzer, Sajjad Khani, Matteo Oliverio, Motoharu Awazawa, Peter Frommolt, Joerg Heeren, Ludger Scheja, Markus Heine, Christoph Dieterich, Hildegard Büning, Ling Yang, Haiming Cao, Dario F. De Jesus, Rohit Kulkarni, Branko Zevnik, Simon E. Tröder, Uwe Knippschild, Peter A. Edwards, Richard G. Lee, Masayuki Yamamoto, Igor Ulitsky, Eduardo Fernandez-Rebollo, Thomas Q. De Aguiar Vallim, Jan-Wilhelm Kornfeld

Biology

Obesity and type 2 diabetes mellitus are global emergencies and long noncoding RNAs (lncRNAs) are regulatory transcripts with elusive functions in metabolism. Here we show that a high fraction of lncRNAs, but not protein-coding mRNAs, are repressed during diet-induced obesity (DIO) and refeeding, whilst nutrient deprivation induced lncRNAs in mouse liver. Similarly, lncRNAs are lost in diabetic humans. LncRNA promoter analyses, global cistrome and gain-of-function analyses confirm that increased MAFG signaling during DIO curbs lncRNA expression. Silencing Mafg in mouse hepatocytes and obese mice elicits a fasting-like gene expression profile, improves glucose metabolism, de-represses lncRNAs and impairs mammalian target of …

Decreased Temperature Variance Associated With Biotic Composition Enhances Coastal Shrub Encroachment, Lauren K. Wood, Spencer Hays, Julie C. Zinnert

Biology Publications

Regime shift from grasslands to shrub-dominated landscapes occur worldwide driven by altered land-use and climate change, affecting landscape function, biodiversity, and productivity. Warming winter temperatures are a main driver of expansion of the native, evergreen shrub, Morella cerifera, in coastal landscapes. Shrub establishment in these habitats alters microclimate, but little is known about seasonal differences and microclimate variance. We assessed influence of shrubs on microclimate variance, community composition, and community physiological functioning across three vegetation zones: grass, transitional, and shrub in a coastal grassland. Using a novel application of a time-series analysis, we interpret microclimatic variance modification and elucidate …

Feeding Behavior Fundamentally Affects Micro-Particle Intake In Mangrove Crabs, Rola Alsharif

Scientific Communication News

No abstract provided.

Human Vs. Bear: Who Needs Salmon More?, Brittany N. Savercool

Scientific Communication News

No abstract provided.

How Corals Avoid Mating Between Different Species, Amanda Kempton

Scientific Communication News

No abstract provided.

Microplastics Invade Manta Ray Feeding Grounds Giving Rise To The Effects Of Global Plastic Pollution, Meghan Ulmer

Scientific Communication News

No abstract provided.

Battle For The Top: Killer Whales Vs. White Sharks, Michael P. Mcdonough

Scientific Communication News

No abstract provided.

Can Ocean Modeling Help Predict Where Cold-Stunned Sea Turtles Wash Up?, Mikayla L. Twiss

Scientific Communication News

No abstract provided.

White Sharks As A Novel Threat To Sea Otter Populations In California, Kimberly S. Schmutz

Scientific Communication News

No abstract provided.

Feeding Ecology Of Invasive Lionfish In Southeast Florida, Ruchao Qian

Scientific Communication News

No abstract provided.

Endangered Whale Species In A Pristine Environment: Pollutant Concentrations Indicative Of A Problem?, Briana R. Coulter

Scientific Communication News

No abstract provided.

No Evidence Of Fine Scale Thermal Adaption In Green Turtles, Taylor Apter

Scientific Communication News

No abstract provided.

New Intervention Method For Halting Stony Coral Tissue Loss Disease, Samantha Buckley

Scientific Communication News

No abstract provided.

Machine Learning Provides A Much-Needed Solution For Marine Mammal Protection, Shaman Patel

Scientific Communication News

No abstract provided.

Ghost Fishing In Coral Reef Ecosystems, Katherine E. Meurer

Scientific Communication News

No abstract provided.

Climate Change Could Impact Narwhal Consumption By Killer Whales, Mykenzee L. Munaco

Scientific Communication News

No abstract provided.

Fishing Industry And Misidentification Leading To Angel Sharks Decline, Gretchen M. Spencer

Scientific Communication News

No abstract provided.