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2016

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Articles 1801 - 1830 of 1869

Full-Text Articles in Biology

Association Of The Female Of Perdita (Xeromacrotera) Cephalotes (Cresson), And A Replacement Name For Perdita Bohartorum Parker (Hymenoptera: Andrenidae), Zach Portman, Terry L. Griswold, James P. Pitts Jan 2016

Association Of The Female Of Perdita (Xeromacrotera) Cephalotes (Cresson), And A Replacement Name For Perdita Bohartorum Parker (Hymenoptera: Andrenidae), Zach Portman, Terry L. Griswold, James P. Pitts

Biology Faculty Publications

The monotypic Perdita subgenus Xeromacrotera Timberlake is currently known only from the male sex. Here, the female of Perdita (Xeromacrotera) cephalotes (Cresson, 1878) is associated, resulting in two new junior synonyms of P. (X.) cephalotes: Perdita (Procockerellia) excellens Timberlake, 1958, new synonym and Perdita (Cockerellia) autumnalis Timberlake, 1977, new synonym. The true number of maxillary palpi are reported, and updated subgeneric and species diagnoses are provided. In addition, Perdita boharti Portman & Griswold, new name, is designated as a replacement name for the primary junior homonym P. bohartorum Parker, 1983 …


Assessing The Success Of Outreach At Preventing The Movement Of Aquatic Invasive Species In Illinois, Ellen Anne Cole Jan 2016

Assessing The Success Of Outreach At Preventing The Movement Of Aquatic Invasive Species In Illinois, Ellen Anne Cole

Master's Theses

Overland transport of recreational boats is the major vector of dispersal for aquatic invasive species among North American waterbodies. These species have large economic and ecosystem impacts, and understanding their movement is essential to understanding the biodiversity and functioning of aquatic ecosystems across the continent. I surveyed Illinois boaters to determine patterns of recreational boat movement and the consistency with which boaters perform actions to prevent the spread of invasive species. Although most boaters perform these actions, a large minority do not and the network for invasive species spread on recreational boats still connects most waterbodies. Next, I interviewed managers …


Chronic Toxicity Of Binary Metal Mixtures Of Cadmium-Zinc And Cadmium-Nickelon Daphnia Magna, Edgar Ramiro Perez Jan 2016

Chronic Toxicity Of Binary Metal Mixtures Of Cadmium-Zinc And Cadmium-Nickelon Daphnia Magna, Edgar Ramiro Perez

Master's Theses

This study characterizes binary-metal mixture effects of cadmium (Cd2+) + zinc (Zn2+) and Cd2+ + nickel (Ni2+) on Daphnia magna. Although acute studies have shown protective Ni2+ (Traudt et al. 2016) and Zn2+ effects (Meyer et al. 2015) against Cd2+ toxicity, no study has fully characterized a protective effect on D. magna at several endpoints (survival, reproduction, growth, and accumulation) on a chronic study. In this study, the titration design was selected to characterize the 21 day (21-d) chronic effects of the binary-metal mixtures on survival, growth, reproduction, and metal accumulation in D. magna. Using this design, increasing concentrations of …


Determination Of Cyclic-Di-Gmp- Controlled Gene Expression In A Pharmacologically Important Bacterium, Morgan A. Stark Jan 2016

Determination Of Cyclic-Di-Gmp- Controlled Gene Expression In A Pharmacologically Important Bacterium, Morgan A. Stark

Undergraduate Honors Thesis Projects

The second messenger molecule cyclic dimeric GMP (c-di-GMP) regulates a myriad of processes in gram-negative bacteria. However, less is known about the roles it plays in gram-positive bacteria. Differential gene expression in three strains of the gram-positive bacterium, Streptomyces coelicolor, is being studied using RNA sequencing and Real Time PCR to gain insight into c-di-GMP signaling. The rmdA rmdB (regulator of morphology and development) double mutant was compared to the wild type strain known as MT1110. The rmdA and rmdB genes are needed for the formation of aerial mycelium, an important step in the life cycle of Streptomyces coelicolor (Hull …


Resurgence Of Acropora Corals On Mid Shelf Patch Reefs, Southwater Caye Marine Reserve, Central Belize, Jillian J. Keefer Jan 2016

Resurgence Of Acropora Corals On Mid Shelf Patch Reefs, Southwater Caye Marine Reserve, Central Belize, Jillian J. Keefer

Undergraduate Honors Thesis Projects

Acropora cervicornis (staghorn) and Acropora palmata (elkhorn) are ecologically important corals that grow quickly and provide topography and refuges for fish and invertebrates. Historically, Acropora was the most abundant coral in shallow patch reef zones in the Caribbean. During the 1980s, white band disease eliminated most Acropora causing a loss in rugosity and an increase of macroalgae on many reefs. Although Acropora remains rare throughout most of the Caribbean, this study documents its partial comeback and possible limiting factors in Southwater Caye Marine Reserve (SWCMR), Central Belize. Patch reefs in the reserve averaged 19% live coral cover with A. palmata …


Ship-Induced Depression Wakes And Shoreline Erosion, Luca Zaggia, Giuliano Lorenzetti, Georgia Manfe, Gian Marco Scarpaf, K. E. Parnell, John Rapaglia, E. Molinaroli Jan 2016

Ship-Induced Depression Wakes And Shoreline Erosion, Luca Zaggia, Giuliano Lorenzetti, Georgia Manfe, Gian Marco Scarpaf, K. E. Parnell, John Rapaglia, E. Molinaroli

Biology Faculty Publications

Shoreline retreat as an effect of ship wakes was studied in a navigation channel of the industrial port of Venice, Italy: the Malamocco -Marghera Channel. The investigation revealed unprecedented erosion rates, up to 4 m y , that determined a total loss of about 1.2 million of m of soil in the period 1970 -2015. This interaction between navigation and the channel margins must be considered in order to understand the past evolution of the central Venice Lagoon and for a sustainable management of the port traffic in the future sea -level rise scenario.


Age Related Decline In Female Lar Gibbon Great Call Performance Suggests That Call Features Correlate With Physical Condition, Thomas A. Terleph, S. Malaivijitnond, Ulrich H. Reichard Jan 2016

Age Related Decline In Female Lar Gibbon Great Call Performance Suggests That Call Features Correlate With Physical Condition, Thomas A. Terleph, S. Malaivijitnond, Ulrich H. Reichard

Biology Faculty Publications

Background

White-handed gibbons (Hylobates lar) are small Asian apes known for living in stable territories and producing loud, elaborate vocalizations (songs), often in well-coordinated male/female duets. The female great call, the most conspicuous phrase of the repertoire, has been hypothesized to function in intra-sexual territorial defense. We therefore predicted that characteristics of the great call would correlate with a caller’s physical condition, and thus might honestly reflect resource holding potential (RHP). Because measurement of RHP is virtually impossible for wild animals, we used age as a proxy, hypothesizing that great call climaxes are difficult to produce and maintain …


Natural History, Phenology, And Stream Use Of Hyla Plicata From The Arroyo Los Axolotes, State Of Mexico, Mexico, J. A. Lemos-Espinal, Geoffrey R. Smith, A. Hernandez Ruiz, R. Montoya Ayala Jan 2016

Natural History, Phenology, And Stream Use Of Hyla Plicata From The Arroyo Los Axolotes, State Of Mexico, Mexico, J. A. Lemos-Espinal, Geoffrey R. Smith, A. Hernandez Ruiz, R. Montoya Ayala

Faculty Publications

No abstract provided.


Amphibians And Reptiles Of The State Of Nuevo Leon, Mexico, J. A. Lemos-Espinal, Geoffrey R. Smith, A. Cruz Jan 2016

Amphibians And Reptiles Of The State Of Nuevo Leon, Mexico, J. A. Lemos-Espinal, Geoffrey R. Smith, A. Cruz

Faculty Publications

No abstract provided.


Amphibians And Reptiles Of The State Of Coahuila, Mexico, With Comparison With Adjoining States, J. A. Lemos-Espinal, Geoffrey R. Smith Jan 2016

Amphibians And Reptiles Of The State Of Coahuila, Mexico, With Comparison With Adjoining States, J. A. Lemos-Espinal, Geoffrey R. Smith

Faculty Publications

No abstract provided.


The Curiosity Of Con, Petrified Breath, And An Accident Known As Blue., Steven Randall Jan 2016

The Curiosity Of Con, Petrified Breath, And An Accident Known As Blue., Steven Randall

Theses and Dissertations

My thesis installation emerged from an interest in visualizing breath. The resulting work came to exist at the intersection between art, biology, and performance.

The unicorn tapestries were used as a generative point of departure to explore the preservation and transformation of images through time, by time, and with time. Reproductions of the six tapestries were each etched into paper and then submerged into solutions of Phenol Red dye, Ferric Ferrocyanide (also known as Prussian Blue), and various forms of sodium chloride. Exhaled breath was used to encrust these images of the tapestries into physical objects which gradually crystallized and …


Dietary Adaptations And Intra- And Interspecific Variation In Dental Occlusal Shape In Hominin And Non-Hominin Primates, Kelsey O'Neill Jan 2016

Dietary Adaptations And Intra- And Interspecific Variation In Dental Occlusal Shape In Hominin And Non-Hominin Primates, Kelsey O'Neill

Theses and Dissertations

Dental morphology and tooth shape have been used to recreate the

dietary adaptations for extinct species, and thus dental variation can provide

information on the relationship between fossil species and their

paleoenvironments. Variation in living species with known behaviors can provide

a baseline for interpreting morphology, and behavior, in the fossil record.

Tooth occlusal surface outlines in hominins and non-hominin primates, and other

mammals, have been used for assessments of taxonomic significance, with

variability often considered as being primarily phylogenetic. Few studies have

attempted to assess how diet might influence the pattern of variability in closely

related species. Here the …


Development Of Ecogeomorphological (Egm) Stream Design And Assessment Tools For The Piedmont Of Alabama, Usa, Brian Helms, Jason Zink, David Werneke, Tom Hess, Zan Price, Greg Jennings, Eve Brantley Jan 2016

Development Of Ecogeomorphological (Egm) Stream Design And Assessment Tools For The Piedmont Of Alabama, Usa, Brian Helms, Jason Zink, David Werneke, Tom Hess, Zan Price, Greg Jennings, Eve Brantley

Research, Publications & Creative Work

Regional data needed for effective stream restoration include hydraulic geometry relationships (i.e., regional curves) and reference channel morphology parameters. Increasingly ecological conditions are being considered when designing, implementing, and assessing restoration efforts. We provide morphology relationships and associated ecological endpoint curves for reference streams in the Alabama piedmont. Twenty-one reference stream reaches were identified in the Tallapoosa drainage of Alabama, ranging from 0.2 to 242 km2 drainage area. Geomorphic surveys were conducted in each stream to measure riffle cross-sections and longitudinal profiles and related to drainage area to develop regional curves. Fish, crayfish, and benthic macroinvertebrates were collected from each …


Isolation And Identification Of Bacterial Endosymbionts In The Brooding Brittle Star Amphipholis Squamata, Abbey Rose Tedford Jan 2016

Isolation And Identification Of Bacterial Endosymbionts In The Brooding Brittle Star Amphipholis Squamata, Abbey Rose Tedford

Honors Theses and Capstones

Symbiotic associations with subcuticular bacteria (SCB) have been identified and studied in numerous echinoderms, including the SCB of the brooding brittle star, Amphipholis squamata. These SCB, however, have not been studied using current next generation sequencing technologies. Previous studies on the SCB of A. squamata placed these bacteria in the genus Vibrio (γ-Proteobacteria), but subsequent studies suggested that the SCB are primarily composed of α-Proteobacteria. The present study examines the taxonomic composition of SCB associated with A. squamata from the Northwest Atlantic. DNA was extracted using a CTAB protocol and 16S rRNA sequences were amplified …


New Verified Nonindigenous Amphibians And Reptiles In Florida Through 2015, With A Summary Of More Than 152 Years Of Introductions, Kenneth L. Krysko, Louis A. Somma, Dustin C. Smith, Christopher R. Gillette, Daniel Cueva, Joseph A. Wasilewski, Kevin M. Enge, Steve A. Johnson, Todd S. Campbell, Jake R. Edwards, Michael R. Rochford, Ryan Tompkins, Jeffrey L. Fobb, Scott Mullin, Christopher J. Lechowicz, Dallas Hazelton, Alície Warren Jan 2016

New Verified Nonindigenous Amphibians And Reptiles In Florida Through 2015, With A Summary Of More Than 152 Years Of Introductions, Kenneth L. Krysko, Louis A. Somma, Dustin C. Smith, Christopher R. Gillette, Daniel Cueva, Joseph A. Wasilewski, Kevin M. Enge, Steve A. Johnson, Todd S. Campbell, Jake R. Edwards, Michael R. Rochford, Ryan Tompkins, Jeffrey L. Fobb, Scott Mullin, Christopher J. Lechowicz, Dallas Hazelton, Alície Warren

Papers in Herpetology

More nonindigenous species occur in Florida, USA, than any other region worldwide and may threaten many of Florida’s natural resources. The frequency of new reports mandates the need for regular updates. Herein, we use photographic and specimen vouchers in addition to literature records to provide updated information on verified nonindigenous amphibians and reptiles in Florida. Between our most recent summary in 2012 and the end of 2015, 38 additional species are known to have been intercepted (n = 2) or introduced (n = 36). We also update the invasion stage of seven species previously reported from Florida and …


The Nutritional Value Of Fecal Sacs: Testing The Parental Nutrition Hypothesis, Amanda W. Burns Jan 2016

The Nutritional Value Of Fecal Sacs: Testing The Parental Nutrition Hypothesis, Amanda W. Burns

College of Graduate Studies: Theses & Dissertations

Nest sanitation is an important aspect of parental investment in birds with altricial nestlings. Passerine nestlings produce fecal matter that is encased in a mucous membrane for easy disposal. These fecal sacs are either removed from the nest and transported a distance away or they are ingested by the adult. A decline in fecal sac ingestion rates as nestlings age has been observed in several species. The parental nutrition hypothesis posits that this pattern can be attributed to increasing digestive efficiency as nestlings age. The parental nutrition hypothesis makes three predictions: fecal sac consumption rates should decrease as nestlings age, …


Diseases And Parasites Of Scallops, Rodman G. Getchell, Roxanna Smolowitz, Sharon E. Mcgladdery, Susan M. Bower Jan 2016

Diseases And Parasites Of Scallops, Rodman G. Getchell, Roxanna Smolowitz, Sharon E. Mcgladdery, Susan M. Bower

Arts & Sciences Faculty Publications

Knowledge of the diseases and parasites of scallops has continued to change since the second edition of this book (McGladdery et al., 2006). Advancements in the field of scallop health research have followed the broader improvements in the ability to identify disease agents in other aquatic animals. Significant progress has been made in diagnostic capability, particularly the ability to distinguish between infectious pathogens and cryptic histopathological lesions in scallops using molecular techniques. Evidence of this is the progress made in combating opportunistic infections of larvae and juveniles of several scallop species reared under hatchery conditions. There are an increasing number …


Conservation Triage: Debating Which Species To Save And Why, Loren B. Byrne Jan 2016

Conservation Triage: Debating Which Species To Save And Why, Loren B. Byrne

Arts & Sciences Faculty Publications

Because of human impacts on the biosphere, so many species are now threatened with extinction that it may not be possible to save them all. Akin to triage in a medical emergency situation, this challenge has brought forth the idea of conservation triage: having to make difficult choices and justifications about which species should be saved and which might not be savable. The goal of the learning activity described in this chapter is to engage students in this debate so they can gain insights into real-world conservation challenges and practice critical thinking and decision making skills in an authentic context. …


Spanish River Carbonatite: Its Benefits And Potential Use As A Soil Supplement In Agriculture, James J Jan 2016

Spanish River Carbonatite: Its Benefits And Potential Use As A Soil Supplement In Agriculture, James J

Theses and Dissertations (Comprehensive)

A critical problem facing agriculture today is being able to consistently and sustainably provide plants with adequate nutrients for growth. With this problem being exacerbated by the ever-increasing human population, new perspectives and techniques are required to ensure global food security. In order to fully realize potential solutions, however, plant growth and nutrition cannot be exclusively focused upon. The soil-microorganism-plant system is comprised of many interconnected and interdependent processes that together support plant growth: it is upon these processes that the focus must be placed. In this work, the agromineral Spanish River Carbonatite (SRC) is characterized using the framework of …


Implications Of Galling Herbivory On Ground Thaw In Canada’S Northern Boreal Forest, Allison Mcmanus Jan 2016

Implications Of Galling Herbivory On Ground Thaw In Canada’S Northern Boreal Forest, Allison Mcmanus

Theses and Dissertations (Comprehensive)

Canada’s northern boreal forest has faced significant climate warming over the past century. This change can have direct and indirect effects on forest dynamics, including altering the disturbance patterns of herbivores and changing the abundance of natural enemies. Warmer air temperatures can impact the distribution and survival of arthropods, both novel species and resident natural enemies. Gall-inducing mites are a resident natural enemy in high latitude forests and have been shown to drive dramatic reductions in gas-exchange rates in infested plants. Physiological reductions in plants can directly affect the shrub energy balance and underlying soil processes. This can have major …


Nickel And Copper Mixture Toxicity To Daphnia In Soft Water, Prachi Deshpande Jan 2016

Nickel And Copper Mixture Toxicity To Daphnia In Soft Water, Prachi Deshpande

Theses and Dissertations (Comprehensive)

Industrially important metals, such as Cu and Ni, sometimes are present at elevated concentrations in lakes, including those in the Sudbury, ON region. Although they are essential metals, their divalent-cation state (Cu2+ and Ni2+) can be toxic at high concentrations in the water. The free-ion toxicity of each of these metals has been studied in isolation, but rarely as a mixture. The economic importance of Cu2+ and Ni2+ makes them essential to study in the context of mixture toxicity. The objectives were to: (1) determine Cu and Ni mixture toxicity to Daphnia through acute LC50 …


Do Toxicity Modifying Factors Influence Acute Or Chronic Toxicity Of Thulium To Hyalella Azteca?, Alexandria H. Loveridge Jan 2016

Do Toxicity Modifying Factors Influence Acute Or Chronic Toxicity Of Thulium To Hyalella Azteca?, Alexandria H. Loveridge

Theses and Dissertations (Comprehensive)

The industrial demand for rare earth elements (REEs) is growing and as a result, environmental exposure is a concern. Very little is understood about the toxicity of REEs in aquatic environments. The objective of this research is to evaluate the acute and chronic toxicity of Tm and to also understand the toxicity modifying influence of dissolved organic matter (DOM) and cationic competition (Ca2+, Mg2+ and Na+). Furthermore, the aim of this study was to determine linkages between Tm bioaccumulation, growth and survival during chronic exposures. Standard methods (Environment Canada) were followed for both 96h acute and 14d chronic tests, in …


Towards 3d In Vitro Models For The Study Of Cardiovascular Tissues And Disease, Claire M. Brougham, Alan J. Ryan, Carolina D. Garciarena, Steve W. Kerrigan, Fergal J. O'Brien Jan 2016

Towards 3d In Vitro Models For The Study Of Cardiovascular Tissues And Disease, Claire M. Brougham, Alan J. Ryan, Carolina D. Garciarena, Steve W. Kerrigan, Fergal J. O'Brien

Articles

The field of tissue engineering is developing biomimetic biomaterial scaffolds which are showing increasing therapeutic potential for the repair of cardiovascular tissues. However, a major opportunity exists to use them as 3D in vitro models for the study of cardiovascular tissues and disease in addition to drug development and testing. These in vitro models can span the gap between 2D culture and in vivo testing thus reducing cost, time and the ethical burden of current approaches. This review outlines the progress to date and requirements for the development of ideal in vitro 3D models for blood vessels, heart valves and …


Detection Of Yersinia Enterocolitica Serotype O:9 In The Faeces Of Cattle With False Positive Reactions In Serological Tests For Brucellosis In Ireland, Don O'Grady, Kevin Kenny, Seamus Power, John Egan, Fergus Ryan Jan 2016

Detection Of Yersinia Enterocolitica Serotype O:9 In The Faeces Of Cattle With False Positive Reactions In Serological Tests For Brucellosis In Ireland, Don O'Grady, Kevin Kenny, Seamus Power, John Egan, Fergus Ryan

Articles

Intestinal infection by Yersinia enterocolitica serotype O:9 (YeO9) in cattle has been linked to false positive serological reactivity (FPSR) in diagnostic tests for brucellosis. Although eradicated in Ireland, brucellosis monitoring still identifies seropositive animals, usually one or two (termed singletons) per herd, which are classed as FPSR. To investigate a link between FPSR and YeO9, faeces and blood were collected from singleton FPSR cattle, and from companion animals, in eight selected herds with more than one FPSR animal, for YeO9 culture and Brucella serology. YeO9 was isolated from 76/474 (16%) FPSR singletons in 309 herds, but not from any of …


Assessing Shoreline Change And Vegetation Cover Adjacent To Back-Barrier Shoreline Stabilization Structures In Georgia Estuaries, Katherine R. Wakefield Jan 2016

Assessing Shoreline Change And Vegetation Cover Adjacent To Back-Barrier Shoreline Stabilization Structures In Georgia Estuaries, Katherine R. Wakefield

College of Graduate Studies: Theses & Dissertations

Anthropogenic stabilization of erosional shorelines by hard-armoring structures is used for protection of property, especially if buildings, historical monuments, cultural resources, or other infrastructure are present. The post-installation effects of shoreline stabilization structures on adjacent shorelines in the back-barrier marshes of coastal Georgia are a concern, and interest in living shorelines as erosion control devices has increased because of their use of natural materials and vegetation. AMBUR shoreline analysis software was used to calculate pre-and post-installation shoreline change rates of shorelines adjacent to riprap and bulkhead structures. There was no significant difference between the post-installation shoreline change rates of the …


Combined Effects Of Tetrakis Hydroxymethyl Phosphonium Chloride And Ammonium On Plankton Community Structure In Blackwater Pond Mesocosms, Marina N. Osier Jan 2016

Combined Effects Of Tetrakis Hydroxymethyl Phosphonium Chloride And Ammonium On Plankton Community Structure In Blackwater Pond Mesocosms, Marina N. Osier

College of Graduate Studies: Theses & Dissertations

Flame retardant chemicals enter aquatic systems through municipal and industrial wastewater, and despite being detected in surface waters, most have not been thoroughly assessed for environmental risk. Halogenated flame retardants, known to be persistent and highly toxic to aquatic organisms are being phased out, and replaced with new or under-tested organophosphorus flame retardants. Organophosphorus flame retardants, such as tetrakis hydroxymethyl phosphonium chloride (THPC), often have similar applications to and are generally not as persistent as halogenated flame retardants. Single-species toxicity tests of organophosphorus flame retardants reveal a wide range of toxicity values within the range of environmentally relevant concentrations in …


Abiotic And Biotic Factors Influence Refuge Use At The Community And Organismal Level, George Todd Jan 2016

Abiotic And Biotic Factors Influence Refuge Use At The Community And Organismal Level, George Todd

College of Graduate Studies: Theses & Dissertations

Animal behavior is influence by a wide range of factors. One factor that can heavily influence behavior is the presence or absence of refuge (i.e., refuge provides a direct benefit to animals’ fitness). Many animals seek refuge to avoid predation despite clear costs to other life processes. The decision to use refuge is complex and anthropogenic activities may alter the abundance of refuge. Artificial refuge structures can be successful in conservation efforts and are an effective means to measure biodiversity. Thus, I used cover boards to examine how habitat structure and season influence vertebrate abundance and diversity in the southeastern …


Genetic Identification With Heteroplasmic Variations In Maternally Related Individuals In Forensic Cases, Ayşen Tezel, Ömer Çeti̇nkaya, Burçak Güzeltepe, Nurgül Kiliç Jan 2016

Genetic Identification With Heteroplasmic Variations In Maternally Related Individuals In Forensic Cases, Ayşen Tezel, Ömer Çeti̇nkaya, Burçak Güzeltepe, Nurgül Kiliç

Turkish Journal of Biology

Mitochondrial DNA (mtDNA), inherited from the mother, is used in a large variety of areas. In order to evaluate the connection between an incident and the victim or suspect in the analysis of criminal cases, DNA was obtained from buccal swabs sampled from 21 volunteers related through the mother's generation. Using Seqscape (v2.5.5) in an ABI 3100x1 capillary electrophoresis system, mtDNA sequence analyses were performed and compared to the revised Cambridge Reference Sequence. Individual mtDNA variations were detected. In three individuals, point heteroplasmy was observed. The results were evaluated according to the mtDNA typing guidelines established by the International Society …


Limbal Stem Cell Deficiency: Special Focus On Tracking Limbal Stem Cells, Santhosh Kacham, Bhaskar Birru, Sreenivasa Rao Parcha, Ramaraju Baadhe Jan 2016

Limbal Stem Cell Deficiency: Special Focus On Tracking Limbal Stem Cells, Santhosh Kacham, Bhaskar Birru, Sreenivasa Rao Parcha, Ramaraju Baadhe

Turkish Journal of Biology

The cornea, the transparent part of the eye that helps in the formation of images, has multiple layers. Among them, the superficial epithelial layer is protected and maintained homeostatically by the limbus, located in the periphery of the cornea. Limbal stem cells are located at the basal layer of the limbus and the loss of these cells is called limbal stem cell deficiency (LSCD). LSCD is characterized by corneal vascularization, inflammation, and conjunctivalization, which ultimately lead to blindness. Several clinical transplantation procedures used for the treatment of LSCD are cultivated limbal epithelial transplantation, simple limbal epithelial transplantation, and cultured oral …


Cancer Stem Cells: Lessons Learned From The Leukemic Stem Cells, Ayten Kandi̇lci̇ Jan 2016

Cancer Stem Cells: Lessons Learned From The Leukemic Stem Cells, Ayten Kandi̇lci̇

Turkish Journal of Biology

Cancer is the second cause of death in Turkey and the frequency of cancer deaths increased from 12% in 2002 to 21% in 2009 ( Özkan et al., 2013). To win the war on cancer, we certainly need to apply well-planned prevention policies, given that it is caused mostly by environmental factors, and to develop more effective therapies. To achieve a cure for the disease, it is crucial to understand the cellular and molecular mechanisms leading to cancer and to therapeutically target all the factors playing a role in the initiation, progression, maintenance, and relapse of the disease, preferably in …