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Online Dictionary Of Invertebrate Zoology: E, Mary Ann Basinger Maggenti, Armand R. Maggenti, Scott L. Gardner

Armand R. Maggenti Online Dictionary of Invertebrate Zoology

ear eave eaves eburnean ecalcarate ecarinate ecaudate ecbolic eccentric ecdemic ecdysial ecdysis ecdysone ecdysotrophic ecesis echinate echinating Echinodermata echinoderms echinopaedium echinostome echiopluteus Echiura echiurans ecitophile ecium eclectic eclipsed eclosion ecoclimate ecocline ecogeographical ecological ecology ecomorph ecomorphic economic ecoparasite ecophene ecophenotype eco¬phenotypic ecosite ecospecies ecosystem ecotone ecotype ecsoma ectad ectadenia ectal ectally ectoblast ectochone ectocochleate ectocommensal ectocrine ectocyst ectoderm ectodermal ectognathous ectohormones ectolecithal ectomere ectomesenchyme ectomesoderm ectoneural ectooecium ectoparasite ectopara¬sitic ectophagous ectophallus ectopic ectoplasm ectoproct Ectoprocta ectoprocts ectoptygma ectosomal ectosome ectospermalege ectostracum ectosymbion ectosymbi¬ont ectothermal ectotrophous ectozoon ecumenical edaphic edaphic factors edaphon edeagus edentate edentulous edge editum edoeagus effect effector efferent …

Online Dictionary Of Invertebrate Zoology: G, Mary Ann Basinger Maggenti, Armand R. Maggenti, Scott L. Gardner

Armand R. Maggenti Online Dictionary of Invertebrate Zoology

galea gallery gallicola gallicolae gallicolous galliphagous galvanotaxis galvanotropism gametangiogamy gametangium gamete gametocyte gametogamy gametogenesis gametogenetic gametogeny gametogonium gametogony gametotoky gamma gamobium gamodeme gamogenesis gamogonic gamogony gamones gamophase ganglia gangliate ganglion ganglionic gap gaper gaping gas gaseous gaster gasterostome gasterotheca gastraea gastraeum gastral gastralia gastric gastrilegous gastrocoele gastrocoelus gastrodermis gastro-ileal gastrolith gastroorbital Gastropoda gastropods gastropores Gastrotricha gastrotrichs gastrovascular gastrozooid gastrula gastrular gathering Gause's gelatigenous gelatin gelatine gelatinous geminate gemma gemmate gemmation gemmipara gemmipares gemmule gemmulostasin gena genacerore genae genal genaponta genatasinus gene genera generalized generation generative generitype generotype Gene's genesiology genetic genetics genic genicular geniculate genital genitalia genitointestinal genocline genocopy genodeme …

A Peptide Core Motif For Binding To Heterotrimeric G Protein Alpha Subunits, William W. Ja, Anirban Adhikari, Ryan J. Austin, Stephen R. Sprang, Richard W. Roberts

Biological Sciences Faculty Publications

Recently, in vitro selection using mRNA display was used to identify a novel peptide sequence that binds with high affinity to Galpha(i1). The peptide was minimized to a 9-residue sequence (R6A-1) that retains high affinity and specificity for the GDP-bound state of Galpha(i1) and acts as a guanine nucleotide dissociation inhibitor (GDI). Here we demonstrate that the R6A-1 peptide interacts with Galpha subunits representing all four G protein classes, acting as a core motif for Galpha interaction. This contrasts with the consensus G protein regulatory(GPR) sequence, a 28-mer peptide GDI derived from the GoLoco (Galpha(i/0)-Loco interaction)/GPR motif that shares no …

Online Dictionary Of Invertebrate Zoology: N, Mary Ann Basinger Maggenti, Armand R. Maggenti, Scott L. Gardner

Armand R. Maggenti Online Dictionary of Invertebrate Zoology

nacre nacreous naiad nail naked nanism nanoid nanitic worker nanometer nanoplankton nanozooid narcosis nasale nascent naso Nassanoff's gland Nassanov's gland Nassanov's gland nasus nasute natal natality rate natant natatory natatory lamellae nates naticid naticiform native natural classification artificial classification natural decrease natural increase natural group natural increase natural requeening supersedure natural selection naupliar eye nauplius eye naupliiform nauplius eye nauplius larva nautilicone nautiliform nautiloid nautiloid navicular neala neallotype neanic neap Nearctic neascus larva nebulous neck neck organ nuchal organ necrobiosis necrocytosis necrophagous necrophoresis necrophoric behavior necrosis necrotize nectar nectobenthic nectocalyx nectophore nectochaeta larva necton nekton nectophore pneumatophore nectopod nectosome nectozooid …

Online Dictionary Of Invertebrate Zoology: L, Mary Ann Basinger Maggenti, Armand R. Maggenti, Scott L. Gardner

Armand R. Maggenti Online Dictionary of Invertebrate Zoology

labella labellum labellar abductor apodeme labellar basal sclerites labellar mesial sclerite labellar sclerite labellum labial labial area labial disc labial glands labial gutter premental gutter labial kidneys labial nephridia labial lumen premental gutter labial mask labial nephridia labial palp/palpus palpi maxillary palp labial plate labial stipes labiostipes labial suture labial veil oral lappets labiate labidophorous labiella labiellum labile labiostipes labis socii labium bia inner lip labral labropalatum clypeopala¬tum labrum labra labrum-epipharynx lac lacerated lacinia lacinea laciniae lacinia mandibulae lacinia mobilis lacinia mobilis laciniate lacteous lactescent lactic acid lacuna ae lacunar system lacunose lacustrine laeotorma ae laeotropic lagena utriculus Lamarckism lamella …

Online Dictionary Of Invertebrate Zoology: M, Mary Ann Basinger Maggenti, Armand R. Maggenti, Scott L. Gardner

Armand R. Maggenti Online Dictionary of Invertebrate Zoology

macerate machopolyp machozooid macraner macrergate macrobiota macrocephalic macrocercous macrochaetae macrocilia macrocnemes macrocyte macroesthetes macroevolution macrofauna macrogamete macrogametocyte macrogamy macrogenesis macrogyne macroic macrolecithal macromere macromesentery macromitosome macromolecule macromutation macronotal macronucleocyte macrophage macrophthalmic macroplankton macropore macropseudogyne macropterous macrosclere macroscopic macroseptum macrosiphon macrosymbiont macrotaxonomy macrotrichia macrotype macrurous maculate madrepore madreporic madreporite malacoid malacology malacophilous malapophysis male male-cell malella malleate malleations malleolus malleoramate malleus malli Malpighian maltha mamelon mammillate manca manchette mancoid mandible mandibular Mandibulata mandibulate manducate manica maniform manitruncus manna manometabola mantle manubrium manuscript marble margaritaceous marginalia marginate marine marita marker marmorate marsh marsupium masked mass mastax mastication masticomorphic mastidion mastigobranch mastigobranchia mastigophore …

Online Dictionary Of Invertebrate Zoology: I J K, Mary Ann Basinger Maggenti, Armand R. Maggenti, Scott L. Gardner

Armand R. Maggenti Online Dictionary of Invertebrate Zoology

I-band I-cells ichnotaxon ichthyophagous iconotype icotype ICZN ideotype idiobiology idiochromatin idiochromosome idiocuticular idiogamy idiogram idiomorphic idionymous idionymy idioplasm idiosoma idiosome idiosphaerotheca idiotaxonomy idiotaxy idiotrichy idiotype idorgan ileocecal ileum imaginal imagination imagine imago imagochrysalis imbricate imbrication immaculate immarginate immature immersed immunity immunogenic imperfect imperforate implex implicate impregnation impressed imprint impunctate inaequipartite inanition inappendiculate inarticulate inaxon inbreed inbreeding incased incertae incidence incidental incipient incised incisions incisor incisura incisure inclinate inclivous inclusion incomplete incrassate incremental incrustation incubation incubatory incudal incudate incudes incumbent incunabulum incurrent incurved incus indented indeterminate index indexes indigenous indigoid indirect inducer induction inductor inductura indumentum indurate indusium industrial inequal inequilateral …

Online Dictionary Of Invertebrate Zoology: P, Mary Ann Basinger Maggenti, Armand R. Maggenti, Scott L. Gardner

Armand R. Maggenti Online Dictionary of Invertebrate Zoology

P-1 pachynema pachyodont pachytene paedogenesis paedomorphosis paedoparthenogenesis pagina pagiopodous palate palette palidium paliform palingenesis palintrope palisade pallial palliobranchial palliolum palliopedal pallioperitoneal pallium palmaria palmars Palmen's palmula palpation palpifer palpiger palpimacula palpus paludicole palule palus pandemic panduriform Pangaea pangamy pangenesis pan¬mictic panmixia panoistic panthalassic pantherine pantropical panzootic papilioform papilla pappus papula papulous parcidentate parecium parenchyma parenchymella parenchymula paria paries parietes parieto-basilar parivincular parocciput paronychium parsimony parthenapogamy parthenita parthenogenesis parthenote partite parturition paruterine parva parviconoid pastinum patabionts patagia patella pathogen pathogenesis pathognomonic pathology patocoles patronymic paturon paucispiral paunch Paurometabola Pauropoda paurostyle Pavan's Pawlowsky's paxilla Pearman's pecilonymy pecten pectunculate pectus pedalium pedamina peddler …

Online Dictionary Of Invertebrate Zoology: O, Mary Ann Basinger Maggenti, Armand R. Maggenti, Scott L. Gardner

Armand R. Maggenti Online Dictionary of Invertebrate Zoology

obconical obcordate obese obimbricate obsite objective synonym oblanceolate oblate obligate facultative obligate parasite facultative parasite obligate symbiont facultative symbiont oblique oblique muscles oblique vein obliterate oblong oblong plates oblongum obovate obpyriform obscure obsite obimbricate obsolescence obsolete obtect obtected obtect pupa exarate pupa obturaculum obturator obtuse acute obtusilingues acutilin¬gues obumbrate obverse obverse side of colony obvolvent occasional species occipital occipital arch occipital carina occipital cilia ocular seta occipital condyles occipital foramen foramen magnum occipital ganglion occipitalia occipital margin occipital notch occipital suture occipital tentacle cirrus occiput occipital occludent margin occludent teeth occlusion plate occlusor occult oceanic zone ocellara ocellus ocellar basin …

Online Dictionary Of Invertebrate Zoology: H, Mary Ann Basinger Maggenti, Armand R. Maggenti, Scott L. Gardner

Armand R. Maggenti Online Dictionary of Invertebrate Zoology

habitat habitude habroderes hackled haem haematodocha haemocoele haemocoelous haemocyte haemolymph haemolysis hae¬mopoietic haemostatic haemoxanthine haft hair haliotoid Haller's halmatometamorphosis halocline halophile halter halteres hamabiosis hamate hamatype hami hamiform hammock hampe hamula hamular hamulohalterae hamulus hamus Hancock's hapaloderes haplobiont haplo-diploidy haploid haplometrosis haplometrotic haploneme haploneural haplont haplophase haplosis haptolachus haptomeri haptomerum haptor Hardy-Weinberg harmonic harmosis harpago harpagones harpes harpoon hastate hastisetae hatching haustellate haustellum haustrulum Hautkorper Hayes' H-band head head-fans heart heautotype hectocotylus heel height heli helical helices helicocone heliophil heliophilic heliophilous heliophobic heliotaxis heliotropism helix helmet helminth helminthiasis helminthic Helminthology helocerous helotism helus hem hemal hemapoiesis hematacyte hematal hematocyte hematodocha …

Telomere Structure And Shortening In Telomerase-Deficient Trypanosoma Brucei, Oliver Dreesen, Bibo Li, George A.M. Cross

Biological, Geological, and Environmental Faculty Publications

Telomerase consists of a reverse transcriptase (TERT) and an RNA that contains a template for telomere-repeat extension. Telomerase is required to prevent telomere erosion and its activity or lack thereof is important for tumorigenesis and ageing. Telomerase has been identified in numerous organisms but it has not been studied in kinetoplastid protozoa. Trypanosoma brucei, the causative agent of African sleeping sickness, evades the host immune response by frequently changing its variant surface glycoprotein (VSG). The single expressed VSG is transcribed from one of ∼20 subtelomeric 'Expression Sites', but the role telomeres might play in regulating VSG transcription and switching is …

Characterization Of A Novel Filarial Serine Protease Inhibitor, Ov-Spi-1, From Onchocerca Volvulus, With Potential Multifunctional Roles During Development Of The Parasite, Louise Ford, David B. Guiliano, Yelena Oksov, Asim K. Debnath, Jing Liu, Steven A. Williams, Mark L. Blaxter, Sara Lustigman

Biological Sciences: Faculty Publications

A novel filarial serine protease inhibitor (SPI) from the human parasitic nematode Onchocerca volvulus, Ov-SPI-1, was identified through the analysis of a molting third-stage larvae expressed sequence tag dataset. Subsequent analysis of the expressed sequence tag datasets of O. volvulus and other filariae identified four other members of this family. These proteins are related to the low molecular weight SPIs originally isolated from Ascaris suumwhere they are believed to protect the parasite from host intestinal proteases. The two Ov-spi transcripts are up-regulated in the molt- ing larvae and adult stages of the development of the parasite. Recombinant Ov-SPI-1 is an …

Online Dictionary Of Invertebrate Zoology: U V, Mary Ann Basinger Maggenti, Armand R. Maggenti, Scott L. Gardner

Armand R. Maggenti Online Dictionary of Invertebrate Zoology

uliginose, uliginous ultradextral ultrasinistral ultrasonic ultrastructure umbel umbilical suture umbilicus umbilicate umbo umbones umbos beak umbonal umbonal angle umbonal cavity umbonal depression umbonal fold umbonal pole umbonal reflection umbonal region umbonal spine umbone umbo umboniform rotelliform umbonuloid umbo-veliger umbraculate umbraculiferous umbrella exumbrella subumbrella umbrella organ sensillum campaniformium unarmed unarticulate uncate unci uncus unciform uncinal plate radula uncinal seta uncinate uncinate mastax uncini uncinus uncus unci undate underbridge undifferentiated undose undulate ungual unguiculus unguiculi unguiculate unguis unguifer unguiferate unguiflexor unguiform unguis ungues ungual uguiculus homodactyl unguitractor unguitractor tendon ungula unguis uniauriculate unibranchiate unicameral unicapsular unicarinate unicellular uniciliate unicolonial unicolorate unicornous unicuspid …

Online Dictionary Of Invertebrate Zoology: Q R, Mary Ann Basinger Maggenti, Armand R. Maggenti, Scott L. Gardner

Armand R. Maggenti Online Dictionary of Invertebrate Zoology

Q-technique quacking quadrangle quadrat quadrate plates quadricapsular quadricolumella columella quadridentate quadrifid quadrilateral quadrimaculate quadripartite quadripinnate quadriprostatic quadriradiate quadrithecal quadrivalve quartet tetrad quasisocial queen queen control queen substance Quenstedt muscles quick muscle phasic muscle quiescence quiescent quincunx xes quincuncial quinone biochrome cochineal quinones quinquedentate quinquefarious quinquelocular race racemose racemose glands rachidian rhacidian rachiform rachiglossate rhachiglossate rachis rachides rachises radial radial radial apophysis radial cell radial gashes radial growth radial lirae carapace costae radial masses radial-medial cross vein radial muscles radial plates radial processes radial ribs radial sector radial skeleton radial symmmetry bilateral symmetry radial vein radianal plate radiate radiate radiate veins …

Online Dictionary Of Invertebrate Zoology: S, Mary Ann Basinger Maggenti, Armand R. Maggenti, Scott L. Gardner

Armand R. Maggenti Online Dictionary of Invertebrate Zoology

sabulose sabulous sac saccate saccharobiose sacciform saccule saccus sacoglossa saddle Saefftigen's sagittae sagittocysts saliva salivarium salivary saltation Saltatoria saltatory saltigrade sanguinivorous sanidasters sapphirine saprobe saprobiont saprobiotic saprophagous saprophyte saprozite saprozoic saprozoite sarcobelum sarcode sarcolemma sarcolysis sarcomere sarcomeric sarcophagous sarcoplasm sarcoplasmic sarcosomes sarcostyle sarcotheca sarothrum saxicavous saxicolous scabellum scabrous scalariform scalaroid scalids scalpellum scalpriform scansorial scape scaphe scaphiform scaphium scaphocerite scaphognathite scaphoid Scaphopoda scapula scapus scarabaeiform scarabaeoid scarified scariose scatophagous scavenger scent sceptrules schemochrome schistosomula schizeckenosy schizocele schizochroal schizocoel schizodont schizogamy schizogenesis schizolophe schizopeltid schizopod schizorhyses Schmidt's Schwann scissorial scissure sclerification sclerite scleroblasts sclerocyte sclerophagous sclerosepta sclerotic scoleces scolecid scoleciform scolecoid …

Online Dictionary Of Invertebrate Zoology: T, Mary Ann Basinger Maggenti, Armand R. Maggenti, Scott L. Gardner

Armand R. Maggenti Online Dictionary of Invertebrate Zoology

tabula tabular tachyauxesis tachyblastic tachygen tachygenesis tachytelic tactic tactile tactoreceptors taenia taeniate taenidium taenioglossate tagma tagmata tagmosis tail tailfan Takakura's talon talus tandem tangent tangoreceptor tanylobous tapetal tapetum tapinoma-odor Tardigrada tardigrades tarsal tarsation tarsite tarsomere tarsungulus tarsus taste tautonomy tautonym taxa taxes taxis taxis taxodont taxometrics taxon taxonomic taxonomist taxonomy tectiform tectostracum tectum teeth teges tegillum tegmen tegmentum tegula tegular tegulum tegumen tegument tegumentary tela telaform telamon telegonic teleiochrysalis telenchium teleoconch teleodont teleology teleotrocha telepod telescope telescopic teletrophic telioderma teliophan telmophage telocentric telodendria telofemur telogonic telolecithal telomitic telophase telophragma telopod telopodite telorhabdions telosonic telostome telosynapsis telosyndesis telotarsus telotaxis telotroch telson …

Online Dictionary Of Invertebrate Zoology: W X Y Z, Mary Ann Basinger Maggenti, Armand R. Maggenti, Scott L. Gardner

Armand R. Maggenti Online Dictionary of Invertebrate Zoology

Wagener's larva waggle dance walking leg pereopod wall warm-blooded homoiothermal warning coloration sematic aposematic pseudaposematic wart verruca tubercle water pore hydropore Waterston's organ water vascular system wax wax gland wax layer wax-plate wax scale web weighting Weismann's ring ring gland wheel organ white body Hensen's gland white cuticle yellow cuticle wholemount whorl width wild type wing ala winter egg summer egg With's organs workers worker jelly xanthic xanthophyll xanthopterin xanthopterine X-chromosomes xenagones xenic axenic polyxenic synxenic trix¬enic xenobiosis xenoecic xenogamy cross-fertilization xenogenesis heterogenesis xenomone allelochemic xenomorphism xenoparasite xerarch succession xeric xerophilous xerophobous xerosere lithosere hydrosere xerothermic fauna xiphidiocercaria microcotylate cer¬caria …

Taxol-Stabilized Microtubules Can Position The Cytokinetic Furrow In Mammalian Cells, Katie Shannon, Julie C. Canman, C. Ben Moree, Jennifer S. Tirnauer, Edward D. Salmon

Biological Sciences Faculty Research & Creative Works

How microtubules act to position the plane of cell division during cytokinesis is a topic of much debate. Recently, we showed that a subpopulation of stable microtubules extends past chromosomes and interacts with the cell cortex at the site of furrowing, suggesting that these stabilized microtubules may stimulate contractility. To test the hypothesis that stable microtubules can position furrows, we used taxol to rapidly suppress microtubule dynamics during various stages of mitosis in PtK1 cells. Cells with stabilized prometaphase or metaphase microtubule arrays were able to initiate furrowing when induced into anaphase by inhibition of the spindle checkpoint. In these …

Dominant Processes Controlling Water Chemistry Of The Pecos River In American Southwest, Fasong Yuan, Seiichi Miyamoto

Biological, Geological, and Environmental Faculty Publications

Here we show an analysis of river flow and water chemistry data from eleven gauging stations along the Pecos River in eastern New Mexico and western Texas, with time spanning 1959–2002. Analysis of spatial relationship between the long-term average flow and total dissolved solids (TDS) concentration allows us to illuminate four major processes controlling river chemistry, namely saline water addition, evaporative concentration with salt gain or loss, dilution with salt gain or loss, and salt storage. Of the 10 river reaches studied, six reaches exhibit the process dominated by evaporative concentration or freshwater dilution with little change in salt load. …

An Investigation Of The Changes Of Species Richness And Distribution Of The Unionidae (Bivalvia: Molusca) Within The Pamunkey Watershed, William Robert Lees

Master's Theses

A survey of the Unionidae within the Pamunkey Watershed was conducted to investigate changes in distribution and species richness compared to a previous survey (Riddick, 1973) conducted over 30 years ago. Species richness decreased from 10 species in the previous survey to four species in the present survey. Notable increases of species richness were found in the upper South Anna and the lower North Anna regions, while sizable decreases were found in the lower South Anna and the upper and middle regions of the Pamunkey River. Regression analyses and t-tests comparing mussel survey data with habitat parameters were conducted to …

Evolution Of Morphological Integration: Developmental Accommodation Of Stress-Induced Variation, Alexander V. Badyaev, Kerry R. Foresman, Rebecca L. Young

Biological Sciences Faculty Publications

Extreme environmental change during growth often results in an increase in developmental abnormalities in the morphology of an organism. The evolutionary significance of such stress-induced variation depends on the recurrence of a stressor and on the degree to which developmental errors can be accommodated by an organism's ontogeny without significant loss of function. We subjected populations of four species of soricid shrews to an extreme environment during growth and measured changes in the patterns of integration and accommodation of stress-induced developmental errors in a complex of mandibular traits. Adults that grew under an extreme environment had lower integration of morphological …

The Let-7 Microrna Family Members Mir-48, Mir-84, And Mir-241 Function Together To Regulate Developmental Timing In Caenorhabditis Elegans, Allison L. Abbott, Ezequiel Alvarez-Saavedra, Eric A. Miska, Nelson C. Lau, David P. Bartel, H. Robert Horvitz, Victor R. Ambros

Biological Sciences Faculty Research and Publications

The microRNA let-7 is a critical regulator of developmental timing events at the larval-to-adult transition in C. elegans. Recently, microRNAs with sequence similarity to let-7 have been identified. We find that doubly mutant animals lacking the let-7 family microRNA genes mir-48 and mir-84 exhibit retarded molting behavior and retarded adult gene expression in the hypodermis. Triply mutant animals lacking mir-48, mir-84, and mir-241 exhibit repetition of L2-stage events in addition to retarded adult-stage events. mir-48, mir-84, and mir-241 function together to control the L2-to-L3 transition, likely by base pairing to complementary sites in the …

Investigating Hydrologic Alteration As A Mechanism Of Fish Assemblage Shifts In Urbanizing Streams, Allison H. Roy, Mary C. Freeman, Byron J. Freeman, Seth J. Wenger, William E. Ensign, Judith L. Meyer

Faculty Articles

Stream biota in urban and suburban settings are thought to be impaired by altered hydrology; however, it is unknown what aspects of the hydrograph alter fish assemblage structure and which fishes are most vulnerable to hydrologic alterations in small streams. We quantified hydrologic variables and fish assemblages in 30 small streams and their subcatchments (area 8-20 km 2) in the Etowah River Catchment (Georgia, USA). We stratified streams and their subcatchments into 3 landcover categories based on imperviousness (20% of subcatchment), and then estimated the degree of hydrologic alteration based on synoptic measurements of baseflow yield. We derived hydrologic variables …

Atypical Pkciota Contributes To Poor Prognosis Through Loss Of Apical-Basal Polarity And Cyclin E Overexpression In Ovarian Cancer, Astrid M. Eder, Xiaomei Sui, Daniel G. Rosen, Laura K. Nolden, Kwai Wa Cheng, John P. Lahad, Madhuri Kango-Singh, Karen H. Lu, Carla L. Warneke, Edward N. Atkinson, Isabelle Bedrosian, Khandan Keyomarsi, Wen-Lin Kuo, Joe W. Gray, Jerry C. P. Yin, Jinsong Liu, Georg Halder, Gordon B. Mills

Biology Faculty Publications

We show that atypical PKCι, which plays a critical role in the establishment and maintenance of epithelial cell polarity, is genomically amplified and overexpressed in serous epithelial ovarian cancers. Furthermore, PKCι protein is markedly increased or mislocalized in all serous ovarian cancers. An increased PKCι DNA copy number is associated with decreased progression-free survival in serous epithelial ovarian cancers. In a Drosophila in vivo epithelial tissue model, overexpression of persistently active atypical PKC results in defects in apical-basal polarity, increased Cyclin E protein expression, and increased proliferation. Similar to the Drosophila model, increased PKCι proteins levels are associated with …

Soy Isoflavone Glycitein Protects Against Beta Amyloid-Induced Toxicity And Oxidative Stress In Transgenic Caenorhabditis Elegans, Astrid Gutierrez-Zepeda, Ross Santell, Zhixin Wu, Marishka Brown, Yanjue Wu, Ikhlas Khan, Christopher D. Link, Baolu Zhao, Yuan Luo

Faculty Publications

Background

Epidemiological studies have associated estrogen replacement therapy with a lower risk of developing Alzheimer's disease, but a higher risk of developing breast cancer and certain cardiovascular disorders. The neuroprotective effect of estrogen prompted us to determine potential therapeutic impact of soy-derived estrogenic compounds. Transgenic C. elegans, that express human beta amyloid (Aβ), were fed with soy derived isoflavones genistein, daidzein and glycitein (100 μg/ml) and then examined for Aβ-induced paralysis and the levels of reactive oxygen species.

Results

Among the three compounds tested, only glycitein alleviated Aβ expression-induced paralysis in the transgenic C. elegans. This activity of …

Rna Turnover: Unexpected Consequences Of Being Tailed, James T. Anderson

Biological Sciences Faculty Research and Publications

In eukaryotic cells, the 3′ poly(A) tails found on mRNA influence their stability and translation. The discovery of a second nuclear poly(A) polymerase complex has fueled a series of reports defining a new and unexpected role for 3′ end poly(A) tails in the nuclear surveillance and turnover of noncoding RNAs and intergenic mRNAs of unknown function.

Ua3/9/5 Conservation Reserve Enhancement Program (Crep), Wku President's Office

WKU Administration Documents

Talking points used by WKU president Gary Ransdell regarding WKU's partnering with Conservation Reserve Enhancement Program.

Toward Sequencing The Sorghum Genome: A U.S. National Science Foundation-Sponsored Workshop Report, Stephen Kresovich, Brad Barbazuk, Joseph A. Bedell, Andrew Borrell, C. Robin Buell, John Burke, Sandra Clifton, Marie-Michéle Cordonnier-Ptratt, Stan Cox, Jeff Dahlberg, John Erpelding, Theresa M. Fulton, Bob Fulton, Lucinda Fulton, Alan R. Gingle, C. Tom Hash, Yinghua Huang, David Jordan, Patricia E. Klein, Robert R. Klein, Jurandir Magalhaes, Richard Mccombie, Paul Moore, John E. Mullet, Peggy Ozias-Akins, Andrew H. Paterson, Kay Porter, Lee Pratt, Bruce Roe, William Rooney, Patrick S. Schnable, David M. Stelly, Mitchell Tuinstra, Doreen Ware, Ujwala Warek

Faculty Publications

Members of the worldwide sorghum (Sorghum spp.) community, including private sector and international scientists as well as community representatives from closely related crops such as sugarcane (Saccharum spp.) and maize (Zea mays), met in St. Louis, Missouri, on November 9, 2004, to lay the groundwork for future advances in sorghum genomics and, in particular, to coordinate plans for sequencing of the sorghum genome. Key developments that made this workshop timely included advances in knowledge of the sorghum genome that provide for the development of a genetically anchored physical map to guide sequence assembly and annotation, the …

Structural And Molecular Characterization Of A Preferred Protein Interaction Surface On G Protein Beta Gamma Subunits, Tara L. Davis, Tabetha M. Bonacci, Stephen R. Sprang, Alan V. Smrcka

Biological Sciences Faculty Publications

G protein betagamma subunits associate with many binding partners in cellular signaling cascades. In previous work, we used random-peptide phage display screening to identify a diverse family of peptides that bound to a common surface on Gbetagamma subunits and blocked a subset of Gbetagamma effectors. Later studies showed that one of the peptides caused G protein activation through a novel Gbetagamma-dependent, nucleotide exchange-independent mechanism. Here we report the X-ray crystal structure of Gbeta(1)gamma(2) bound to this peptide, SIGK (SIGKAFKILGYPDYD), at 2.7 A resolution. SIGK forms a helical structure that binds the same face of Gbeta(1) as the switch II region …

Two-Dimensional Gel Analysis Of The Heat-Shock Response In Marine Snails (Genus Tegula): Interspecific Variation In Protein Expression And Acclimation Ability, Lars Tomanek

Biological Sciences

The degree to which temperature acclimation modifies the acute synthesis of the entire heat-shock protein (Hsp) complement is still unknown, but it may constitute an important mechanism for understanding the differences in acclimation ability among closely related ectothermic species that occupy widely varying thermal environments. In general, eurythermal (heat-tolerant) species modify physiological function in response to an increase in acclimation temperature to a greater extent than stenothermal (heat-sensitive) species. In the present work I used ³⁵S-labelled amino acids and two-dimensional gel electrophoresis to test this assumption for how acclimation affects acute Hsp expression (referred to as phenotypic plasticity) in …