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2000

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Articles 151 - 180 of 330

Full-Text Articles in Biology

Metals And Metallothionein In The Liver Of Raccoons: Utility For Environmental Assessment And Monitoring, Joanna Burger, Christine G. Lord, Edward J. Yurkow, Lynn Mcgrath, Karen F. Gaines, I. Lehr Brisbin Jr., Michael Gochfeld Jan 2000

Metals And Metallothionein In The Liver Of Raccoons: Utility For Environmental Assessment And Monitoring, Joanna Burger, Christine G. Lord, Edward J. Yurkow, Lynn Mcgrath, Karen F. Gaines, I. Lehr Brisbin Jr., Michael Gochfeld

Faculty Research & Creative Activity

The relationship between metallothionein levels and concentrations of several metals and radionuclides was examined in liver tissues of raccoons (Procyon lotor, n = 47) from the Department of Energy’s Savannah River Site in South Carolina to determine the applicability of metallothioneins as an initial screening device for exposure assessment in free-living mammals and environmental monitoring. Using a fluorescent marker and a cell sorter to measure metallothionein, a significant positive correlation was found across animals between levels of metallothioneins and concentrations of selenium (Pearson’s r = .30) , mercury (Pearson’s r = .31) , and copper (Pearson’s r = .30) in …

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Characterization Of Chimeric Lipopolysaccharides From Escherichia Coli Strain Jm109 Transformed With Lipooligosaccharide Synthesis Genes (Lsg) From Haemophilus Influenzae, Nancy J. Phillips, T. J. Miller, J. J. Engstrom, William Melaugh, R. Mclaughlin, M A. Apicella, B W. Gibson Jan 2000

Characterization Of Chimeric Lipopolysaccharides From Escherichia Coli Strain Jm109 Transformed With Lipooligosaccharide Synthesis Genes (Lsg) From Haemophilus Influenzae, Nancy J. Phillips, T. J. Miller, J. J. Engstrom, William Melaugh, R. Mclaughlin, M A. Apicella, B W. Gibson

Chemistry Faculty Publications

Previously, we reported the expression of chimeric lipopolysaccharides (LPS) in Escherichia coli strain JM109 (a K-12 strain) transformed with plasmids containing Haemophilus influenzae lipooligosaccharide synthesis genes (lsg) (Abu Kwaik, Y., McLaughlin, R. E., Apicella, M. A., and Spinola, S. M. (1991) Mol. Microbiol. 5, 2475–2480). In this current study, we have analyzed the O-deacylated LPS and free oligosaccharides from three transformants (designated pGEMLOS-4, pGEMLOS- 5, and pGEMLOS-7) by matrix-assisted laser desorption ionization, electrospray ionization, and tandem mass spectrometry techniques, along with composition and linkage analyses. These data show that the chimeric LPS consist of the complete E. coli LPS core …

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Predation Rates On Real And Artificial Nests Of Grassland Birds, William B. Davison, Eric K. Bollinger Jan 2000

Predation Rates On Real And Artificial Nests Of Grassland Birds, William B. Davison, Eric K. Bollinger

Faculty Research & Creative Activity

We estimated nesting success at real and artificial nests of grassland birds to test the influence of nest type, nest position, and egg size on predation rates. We distributed wicker nests and realistic woven-grass nests baited with a clay egg and either a Northern Bobwhite (Colinus virginianus) egg or a House Sparrow (Passer domesticus) egg in four grasslands that were part of the Conservation Reserve Program in east-central Illinois. Nesting success averaged 86.5% for 12 days of exposure for artificial nests. For real nests, nesting success was markedly lower, averaging 39% over the entire nesting cycle and 59% during approximately …

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Time Course And Magnitude Of Synthesis Of Heat-Shock Proteins In Congeneric Marine Snails (Genus Tegula) From Different Tidal Heights, Lars Tomanek, George N. Somero Jan 2000

Time Course And Magnitude Of Synthesis Of Heat-Shock Proteins In Congeneric Marine Snails (Genus Tegula) From Different Tidal Heights, Lars Tomanek, George N. Somero

Biological Sciences

The time course and magnitude of the heat-shock response in relation to severity of thermal stress are important, yet poorly understood, aspects of thermotolerance. We examined patterns of protein synthesis in congeneric marine snails (genus Tegula) that occur at different heights along the subtidal to intertidal gradient after a thermal exposure (30°C for 2.5 h, followed by 50 h recovery at 13°C) that induced the heat-shock response. We monitored the kinetics and magnitudes of protein synthesis by quantifying incorporation of 35S-labeled methionine and cysteine into newly synthesized proteins and observed synthesis of putative heat-shock proteins (hsp’s) of size …

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Energetic Dynamics And Anuran Breeding Phenology: Insights From A Dynamic Game, Shannon J. Mccauley, Sarah S. Bouchard, Brian J. Farina, Kavita Isvaran, Suhel Quader, Daniel W. Wood, Colette M. St. Mary Jan 2000

Energetic Dynamics And Anuran Breeding Phenology: Insights From A Dynamic Game, Shannon J. Mccauley, Sarah S. Bouchard, Brian J. Farina, Kavita Isvaran, Suhel Quader, Daniel W. Wood, Colette M. St. Mary

Biological Sciences

We designed a dynamic optimization model to examine anuran-breeding phenologies. We evaluated the fitness consequences for males adopting one of four alternative strategies: calling, satelliting, foraging, or hiding. Various factors potentially influence male behavior, including energy reserves, predation risk, cost of calling, probability of finding food, distribution of male energy states in the population, and probability of surviving to another breeding season. We manipulated these parameters to determine how strongly each affects breeding phenology and chorus structure. Manipulating parameters related to the energetic costs and benefits of individual decisions, we generated the three basic patterns of anuran breeding phenology: explosive, …

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Optical Fractionation Of Chlorophyll And Primary Production For Coastal Waters Of The Southern Ocean, Mark A. Moline, Barbara B. Prezelin Jan 2000

Optical Fractionation Of Chlorophyll And Primary Production For Coastal Waters Of The Southern Ocean, Mark A. Moline, Barbara B. Prezelin

Biological Sciences

Our objective was to quantify the potential variability in remotely sensed chlorophyll a (Chl a) and primary productivity in coastal waters of the Southern Ocean. From data collected throughout the springs/summers of 1991–1994, we calculated the proportion of water column Chl a and primary productivity within the upper optical attenuation length (K −1 par) and the satellite-weighted depth. The temporal variability was resolved every 2–3 days and was observed to be greater within years than between years. Three-year averages (n=223) revealed that 10.2 ± 3.6% of total Chl a and 14.8 ± 6.5% of production occurred …

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The Global Decline Of Reptiles, Deja’ Vu Amphibians, J. Whitfield Gibbons, David E. Scott, Travis J. Ryan, Kurt A. Buhlmann, Tracey D. Tiuberville, Brian S. Metts, Judith L. Greene, Tony Mills, Yale Leiden, Sean Poppy, Christopher T. Winne Jan 2000

The Global Decline Of Reptiles, Deja’ Vu Amphibians, J. Whitfield Gibbons, David E. Scott, Travis J. Ryan, Kurt A. Buhlmann, Tracey D. Tiuberville, Brian S. Metts, Judith L. Greene, Tony Mills, Yale Leiden, Sean Poppy, Christopher T. Winne

Scholarship and Professional Work - LAS

Reptile species are declining on a global scale. Six significant threats to reptile populations are habitat loss and degradation, introduced invasive species, environmental pollution, disease, unsustainable use, and global climate change.

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Reflections Of A Naturalist: Papers Honoring Professor Eugene D. Fleharty, Jerry R. Choate Jan 2000

Reflections Of A Naturalist: Papers Honoring Professor Eugene D. Fleharty, Jerry R. Choate

Fort Hays Studies Series

Science and academia tend to be dominated by persons who are utterly brilliant, or who are proficient at self-promotion, or who are willing to sacrifice their personal lives and work twice as hard as their peers, or who exhibit some combination of these attributes. Occasionally, however, someone comes along who is just "ordinary" compared with academic overachievers but whose accomplishments far exceed reasonable expectations. Eugene D. Fleharty is such a person. Although he is extraordinarily bright, few would describe him as utterly brilliant. He has never been inclined to "toot his own horn" or otherwise promote himself. And, although he …

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A Scanning Electron Microscopic Study Of The Infection Of Water Oak (Quercus Nigra) By Taphrina Caerulescens, Josephine Taylor, Dale O. Birdwell Jan 2000

A Scanning Electron Microscopic Study Of The Infection Of Water Oak (Quercus Nigra) By Taphrina Caerulescens, Josephine Taylor, Dale O. Birdwell

Faculty Publications

The fungal pathogen Taphrina caerulescens was isolated from leaves of water oak (Quercus nigra) exhibiting symptoms of oak leaf blister. Healthy leaves were inoculated with a suspension of cells from pure culture in order to examine the infection process. Scanning electron microscopy was used to monitor budding of T. caerulescens cells, formation of germ tubes, and indirect penetration of leaf tissue through stomata, which occurred within 48 h post-inoculation. Direct penetration was not observed.

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Home Ranges Of Rat Snakes (Colubridae: Elaphe) In Different Habitats, Stephen J. Mullin, William H. N. Gutzke, Gary D. Zenitsky, Robert J. Cooper Jan 2000

Home Ranges Of Rat Snakes (Colubridae: Elaphe) In Different Habitats, Stephen J. Mullin, William H. N. Gutzke, Gary D. Zenitsky, Robert J. Cooper

Faculty Publications

Based on our findings, we suggest that rat snakes represent not only a major predator of kites, but also of other canopy and mid-story nesting species in the southeastern United States. For example, rat snakes are the most dominant snake nest predator of bird nests throughout the Southeast (DeGregorio et al. 2014) and are skilled tree climbers that often occupy arboreal habitats (Jackson 1976, Keller and Heske 2000, Sperry et al. 2009), particularly in bottomland forests (Mullin et al. 2000, Carfagno and Weatherhead 2009). Thus, the role of rat snakes as predators of nests above the understory is likely underappreciated …

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Binding Of Urate And Caffeine To Hemocyanin Of The Lobster Homarus Vulgaris (E.) As Studied By Isothermal Titration Calorimetry †, Michael A. Menze, Nadja Hellmann, Heinz Decker, Manfred K. Grieshaber Jan 2000

Binding Of Urate And Caffeine To Hemocyanin Of The Lobster Homarus Vulgaris (E.) As Studied By Isothermal Titration Calorimetry †, Michael A. Menze, Nadja Hellmann, Heinz Decker, Manfred K. Grieshaber

Faculty Research & Creative Activity

Hemocyanin serves as an oxygen carrier in the hemolymph of the European lobster Homarus Vulgaris. The oxygen binding behavior of the pigment is modulated by metabolic effectors such as lactate and urate. Urate and caffeine binding to 12-meric hemocyanin (H. Vulgaris) was studied using isothermal titration calorimetry (ITC). Binding isotherms were determined for fully oxygenated hemocyanin between pH 7.55 and 8.15. No pH dependence of the binding parameters could be found for either effector. Since the magnitude of the Bohr effect depends on the urate concentration, the absence of any pH dependence of urate and caffeine binding to oxygenated hemocyanin …

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Foraging Ecology Of The Endangered Wood Stork Recorded In The Stable Isotope Signature Of Feathers, Christopher S. Romanek, Karen F. Gaines, A. L. Bryan Jr., I. L. Brisbin Jr. Jan 2000

Foraging Ecology Of The Endangered Wood Stork Recorded In The Stable Isotope Signature Of Feathers, Christopher S. Romanek, Karen F. Gaines, A. L. Bryan Jr., I. L. Brisbin Jr.

Faculty Research & Creative Activity

Down feathers and regurgitant were collected from nestling wood storks (Mycteria americana) from two inland and two coastal breeding colonies in Georgia. The stable isotopic ratios of carbon ( 13 C/12 C) and nitrogen ( 15N/ 14N) in these materials were analyzed to gain insights into the natal origins of juvenile storks and the foraging activities of adults. Down feathers differed in δ 13 C between inland and coastal colonies, having average isotopic values that reflected the sources of carbon fixed in biomass at the base of the food web. Feathers from the inland colonies differed between colonies in δ …

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Sagina (Caryophyllaceae) In Illinois: An Update, Gordon C. Tucker Jan 2000

Sagina (Caryophyllaceae) In Illinois: An Update, Gordon C. Tucker

Faculty Research & Creative Activity

No abstract provided.

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Sagina (Caryophyllaceae) In Illinois: An Update, Gordon Tucker Jan 2000

Sagina (Caryophyllaceae) In Illinois: An Update, Gordon Tucker

Faculty Research & Creative Activity

No abstract provided.

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Predation Rates On Real And Artificial Nests Of Grassland Birds, William Davison, Eric Bollinger Jan 2000

Predation Rates On Real And Artificial Nests Of Grassland Birds, William Davison, Eric Bollinger

Faculty Research & Creative Activity

We estimated nesting success at real and artificial nests of grassland birds to test the influence of nest type, nest position, and egg size on predation rates. We distributed wicker nests and realistic woven-grass nests baited with a clay egg and either a Northern Bobwhite (Colinus virginianus) egg or a House Sparrow (Passer domesticus) egg in four grasslands that were part of the Conservation Reserve Program in east-central Illinois. Nesting success averaged 86.5% for 12 days of exposure for artificial nests. For real nests, nesting success was markedly lower, averaging 39% over the entire nesting cycle and 59% during approximately …

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Season And Distance From Forest - Old Field Edge Affect Seed Predation By White-Footed Mice, Scott Meiners, James Mccormick Jan 2000

Season And Distance From Forest - Old Field Edge Affect Seed Predation By White-Footed Mice, Scott Meiners, James Mccormick

Faculty Research & Creative Activity

We studied the spatial pattern of seed predation across a forest-old field edge in both fall and winter to assess the potential for seed predators to influence plant spatial patterns. We used a 100 x 100 m grid that began 30 m inside the forest and extended 60 m into the old field. Inside this grid we placed seed stations at regular 10 m intervals and monitored seed removal. Seed predation varied significantly across the edge gradient in both fall and winter with the highest rate of seed removal at the edge in both trials. The spatial pattern of seed …

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Evaluation Of The Performance Enhancement Of Silicone Biofouling-Release Coatings By Oil Incorporation, Kathryn Truby, Christina Wood, Judith Stein, James Cella, John Carpenter, Christopher Kavanagh, Geoff Swain, Deborah Wiebe, David Lapota, Anne Meyer, Eric Holm, Dean Wendt, Celia Smith, Jean Montemarano Jan 2000

Evaluation Of The Performance Enhancement Of Silicone Biofouling-Release Coatings By Oil Incorporation, Kathryn Truby, Christina Wood, Judith Stein, James Cella, John Carpenter, Christopher Kavanagh, Geoff Swain, Deborah Wiebe, David Lapota, Anne Meyer, Eric Holm, Dean Wendt, Celia Smith, Jean Montemarano

Biological Sciences

In response to increased evidence of ecosystem damage by toxic antifouling paints, many researchers have developed nontoxic silicone fouling release coatings. The fouling release capability of these Systems may be improved by adding nonbonding silicone oils to the coating matrix. This idea has been tested by comparing the adhesion strength of hard- and soft-fouling organisms on a cured polydimethylsilicone (PDMS) network to that of the same network containing free polydi-methyldiphenylsilicone (PDMDPS) oil at five exposure sites in North America and Hawaii. Fouling coverage is discussed, together with the bioadhesion data, to emphasize that although these coatings foul the fouling is …

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New Specimens Of Late Quaternary Extinct Mammals From Caves In Sanchez Ramirez Province, Dominican Republic, Donald A. Mcfarlane, Abel Vale, Keith Christenson, Joyce Lundberg, Gabriel Atilles, Stein Erik Lauritzen Jan 2000

New Specimens Of Late Quaternary Extinct Mammals From Caves In Sanchez Ramirez Province, Dominican Republic, Donald A. Mcfarlane, Abel Vale, Keith Christenson, Joyce Lundberg, Gabriel Atilles, Stein Erik Lauritzen

WM Keck Science Faculty Papers

During the late Quaternary, the island of Hispaniola supported one of the most diverse mammalian faunas in the West Indies. Much of this diversity was lost to extinction in the past 100,000 years, but the timing of these events is poorly known. Here we report the paleontological findings of a multidisciplinary investigation of caves in the central Dominican Republic. These findings include new 'last occurrence' dates for the rodents Isolobodon portoricensis and Brotomys cf. voratus that take these genera to the dawn of the historic era; a first record of a last-interglacial sloth, and the first report of the upper …

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Structure Of A Rat Α1-Macroglobulin Receptor-Binding Domain Dimer, Tsan Xiao, Dianne L. Decamp, Stephen R. Sprang Jan 2000

Structure Of A Rat Α1-Macroglobulin Receptor-Binding Domain Dimer, Tsan Xiao, Dianne L. Decamp, Stephen R. Sprang

Biological Sciences Faculty Publications

α-Macroglobulin inhibits a broad spectrum of proteinases by forming macromolecular cages inside which proteinases are cross-linked and trapped. Upon formation of a complex with proteinase, α-macroglobulin undergoes a large conformational change that results in the exposure of its receptor-binding domain (RBD). Engagement of this domain by α-macroglobulin receptor permits clearance of the α-macroglobulin: proteinase complex from circulation. The crystal structure of rat α1-macroglobulin RBD has been determined at 2.3 Å resolution. The RBD is composed of a nine-stranded β-sandwich and a single α-helix that has been implicated as part of the receptor binding site and that lies on …

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Evidence For Microbial Fe(Iii) Reduction In Anoxic, Mining-Impacted Lake Sediments (Lake Coeur D’Alene, Idaho), David E. Cummings, Anthony W. March, Benjamin Bostick, Stefan Spring, Frank Caccavo Jr., Scott Fendorf, Frank Rosenzweig Jan 2000

Evidence For Microbial Fe(Iii) Reduction In Anoxic, Mining-Impacted Lake Sediments (Lake Coeur D’Alene, Idaho), David E. Cummings, Anthony W. March, Benjamin Bostick, Stefan Spring, Frank Caccavo Jr., Scott Fendorf, Frank Rosenzweig

Biological Sciences Faculty Publications

Mining-impacted sediments of Lake Coeur d'Alene, Idaho, contain more than 10% metals on a dry weight basis, approximately 80% of which is iron. Since iron (hydr)oxides adsorb toxic, ore-associated elements, such as arsenic, iron (hydr)oxide reduction may in part control the mobility and bioavailability of these elements. Geochemical and microbiological data were collected to examine the ecological role of dissimilatory Fe(III)-reducing bacteria in this habitat. The concentration of mild-acid-extractable Fe(II) increased with sediment depth up to 50 g kg−1, suggesting that iron reduction has occurred recently. The maximum concentrations of dissolved Fe(II) in interstitial water (41 mg liter …

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Biospheric Cooling And The Emergence Of Intelligence, David Schwartzman, George Middendorf Jan 2000

Biospheric Cooling And The Emergence Of Intelligence, David Schwartzman, George Middendorf

Department of Biology Faculty Publications

The long-term cooling history of the Earth's biosphere implies a temperature constraint on the timing of major events in biologic evolution, e.g., emergence of cyanobacteria, eucaryotes and Metazoa apparently occurred at times when temperatures were near their upper growth limits. Could biospheric cooling also have been a necessary condition for the emergence of veterbrates and their encephalization? The upper temperature limit for vertebrate growth is about 10 degrees below the limit for Metazoa (50 degrees C). Heterothermy followed by full homeothermy was likely a necessary condition for greater encephalization because of the energy requirement of larger brains. The temperature differential …

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A Survey Of Organochlorine Pesticide Contamination In Costa Rican Wildlife, Mark Wieland '00 Jan 2000

A Survey Of Organochlorine Pesticide Contamination In Costa Rican Wildlife, Mark Wieland '00

Honors Projects

Amphibians, turtles, rodents, and birds collected from a tropical conservation area in northwestern Costa Rica where pesticides are not directly applied were analyzed for organochlorine (OC) pesticide contamination. Six of thirty-nine amphibians (three of eight species), three of six turtles (two species), one of eight rodents (one species), and nine of twenty-five insectiverous birds (four species) contained OC compounds ranging from 2.77 ng/g to 277.70 ng/g. The most frequently detected compound (found in thirteen organisms) was p,p'-DDE. Heptachlor, delta-BHC, dieldrin, endosulfan II, and p,p' -DDD were each found in four or more organisms, while eight additional OC compounds were detected …

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Mainstreaming Feminist Critique Into The Biology Curriculum, Scott F. Gilbert, Biology And Gender Study Group Jan 2000

Mainstreaming Feminist Critique Into The Biology Curriculum, Scott F. Gilbert, Biology And Gender Study Group

Biology Faculty Works

No abstract provided.

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Aeromycological Spore Loads At A Newly Activated Compost Facility, Steven R. Mcgreevy Jan 2000

Aeromycological Spore Loads At A Newly Activated Compost Facility, Steven R. Mcgreevy

Honors Theses, 1963-2015

Composting facilities, because of the processes that occur there, may be associated with increased fungal spore loads in the air. We monitored the spore loads present at a newly activated composting facility (Mississippi Topsoils, Inc.; Cold Spring, MN) before and after its activation during October and November of 1999. Petri dishes were arrayed on the downwind side of the compost site and exposed for a range of time periods. The exposed petri dishes were incubated for 48 hours and the number of yeast-like, filamentous, and total fungal colonyforming-units (CFUs) was recorded. The spore load data were also compared to weather …

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Evaluation Of Fish Population Estimation By Removal Sampling In King's Creek, Kansas, Hope Phillips Jan 2000

Evaluation Of Fish Population Estimation By Removal Sampling In King's Creek, Kansas, Hope Phillips

Honors Theses, 1963-2015

Population estimation is an integral part of fisheries science. Using electrofishing to conduct a multiple-pass depletion-removal method to estimate population parameters is common. However, this method is time consuming and labor intensive. Recent research suggests that, under certain circumstances, reliable population estimates from a single-pass electrofishing event can be obtained. The objectives of this study were 1) to determine if fish density and catch-per-unit-effort (CPUE) from a single-pass electrofishing event is correlated with population density estimates obtained from the depletion-removal method and 2) to describe relationships among habitat variables and probability of capture from electrofishing. The study was conducted on …

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Ego-1 Is Related To Rna-Directed Rna Polymerase And Functions In Germ-Line Development And Rna Interference In C. Elegans, Anne Smardon, Jill M. Spoerke, Steven C. Stacey, Marcia E. Klein, Nancy Mackin, Eleanor M. Maine Jan 2000

Ego-1 Is Related To Rna-Directed Rna Polymerase And Functions In Germ-Line Development And Rna Interference In C. Elegans, Anne Smardon, Jill M. Spoerke, Steven C. Stacey, Marcia E. Klein, Nancy Mackin, Eleanor M. Maine

Biology - All Scholarship

Background: Cell-fate determination requires that cells choose between alternative developmental pathways. For example, germ cells in the nematode worm Caenorhabditis elegans choose between mitotic and meiotic division, and between oogenesis and spermatogenesis. Germ-line mitosis depends on a somatic signal that is mediated by a Notch-type signaling pathway. The ego-1 gene was originally identified on the basis of genetic interactions with the receptor in this pathway and was also shown to be required for oogenesis. Here, we provide more insight into the role of ego-1 in germ-line development. Results: We have determined the ego-1 gene structure and the molecular basis of …

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Paradigm Shifts In Neural Induction, Scott F. Gilbert Jan 2000

Paradigm Shifts In Neural Induction, Scott F. Gilbert

Biology Faculty Works

The molecularization of developmental biology was originally seen as a challenge to the integrity of that discipline. However, important new insights from the analysis of gene expression soon transformed the field from one of experimental anatomy to one of developmental genetics. One of the main areas to be transformed from an anatomical to a molecular study was « primary embryonic induction ». The molecular analyses showed that some of the fundamental concepts concluded from the experimental embryological approach to primary embryonic induction were false. First, the neural fate of cells was not being induced. Rather, the epidermal fate was induced …

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Comparing Genotypic And Phenotypic Methods For Differentiating Strains Of Escherichia Coli Isolated From The Environment, Lateef Y. Saffore Jan 2000

Comparing Genotypic And Phenotypic Methods For Differentiating Strains Of Escherichia Coli Isolated From The Environment, Lateef Y. Saffore

Theses, Dissertations and Capstones

Escherichia coli is a Gram-negative, oxidase-negative, lactose fermenting rod belonging to the family Enterohacleriaceae. The enteric bacteria are common inhabitants of animal and human guts, but are not considered to be native to the environment. The presence of E. coli and similar enteric bacteria (coliforms) in surface water or groundwater implies the presence of fecal contamination from human or animal sources. E. coli has been used as an indicator of sewage-contaminated water since the 1930's and some strains are also causative agents of food or waterborne disease (Francy et al., 1993). The severity of disease can vary markedly depending …

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Cytotoxic Mab From Rheumatic Carditis Recognizes Heart Valves And Laminin, Jeffrey E. Galvin, Mark E. Hemric, Kent Ward, Madeleine W. Cunningham Jan 2000

Cytotoxic Mab From Rheumatic Carditis Recognizes Heart Valves And Laminin, Jeffrey E. Galvin, Mark E. Hemric, Kent Ward, Madeleine W. Cunningham

Faculty Publications and Presentations

Anti-streptococcal antibodies cross-reactive with N-acetyl-bD-glucosamine (GlcNAc) and myosin are present in the sera of patients with rheumatic fever (RF). However, their role in tissue injury is not clear. In this study, we show that anti-GlcNAc/anti-myosin mAb 3.B6 from a rheumatic carditis patient was cytotoxic for human endothelial cell lines and reacted with human valvular endothelium and underlying basement membrane. Reactivity of mAb 3.B6 with the valve was inhibited by human cardiac myosin > laminin > GlcNAc. The mAb 3.B6 epitopes were localized in fragments of human cardiac myosin, including heavy meromyosin (HMM), the S1 subfragment, and two light meromyosin (LMM) peptides containing …

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Blue-Throated Hummingbird Song: A Pinnacle Of Nonoscine Vocalizations, Millicent S. Ficken, Kathryn M. Rusch, Sandra J. Taylor, Donald R. Powers Jan 2000

Blue-Throated Hummingbird Song: A Pinnacle Of Nonoscine Vocalizations, Millicent S. Ficken, Kathryn M. Rusch, Sandra J. Taylor, Donald R. Powers

Faculty Publications - Department of Biological & Molecular Science

Little is known about the structure and function of hummingbird vocalizations. We studied the vocalizations of Blue-throated Hummingbirds (Lampornis clemenciae) at two sites in southeastern Arizona. Songs were produced by males and females. Male songs consisted of arrays of notes organized in clusters of ‘‘song units.’’ Within sites, all males shared the same song units. Individual differences occurred in some temporal aspects of song, and slight but consistent differences in note structure occurred between the two sites. The organization of units within songs was marked by rigid syntax, and long songs were produced by agglutination of units. Male …

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