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Full-Text Articles in Biology

How Salivary Glands Recover From Fibrotic Injury, Gabriella Majka Dec 2021

How Salivary Glands Recover From Fibrotic Injury, Gabriella Majka

Biological Sciences

Extracellular matrix deposition is required for repair after injury, but if left unresolved can result in fibrosis. Fibrosis is an excess deposition of extracellular matrix proteins following injury or aging that leads to eventual organ dysfunction. One surgical model that we have used to study mechanisms of fibrosis is the salivary gland ductal ligation model. During the process of ligation, a clip is placed on the main ducts of the submandibular (SMG) and sublingual gland (SLG) which leads from the salivary glands to the mouth. This causes the gland to atrophy, or waste away, resulting in decreased acinar cell differentiation …


Occupancy Modeling Of Western Monarch Thanksgiving Counts: Negative Impacts Of Incomplete Resurveys And Uneven Sampling Efforts, Keegan M. Mclean May 2021

Occupancy Modeling Of Western Monarch Thanksgiving Counts: Negative Impacts Of Incomplete Resurveys And Uneven Sampling Efforts, Keegan M. Mclean

Biological Sciences

Western monarch butterflies (sp. Danaus plexippus) are undergoing a severe decline that rivals those occurring among insects across the globe. Despite the estimation of population abundance, growth rates, and extinction probabilities, no analyses have investigated spatiotemporal patterns of decline in the western monarch population. I performed occupancy modeling of Western Monarch Thanksgiving Count (WMTC) data. The data was constrained spatially and temporally, with sites grouped into occupancy bins by latitude and year. Occupancy probabilities (psi) were estimated for each intersection of a latitude and time bin and detection probabilities (p) were estimated for each time bin. Psi increased slightly …


Comparative Effects Of Chemical And Physical Sunscreen On Fertilization Of Purple Sea Urchins (Strongylocentrotus Purpuratus), Marilla Lippert, Maurice Codespoti Goodman, Nikki Adams Feb 2021

Comparative Effects Of Chemical And Physical Sunscreen On Fertilization Of Purple Sea Urchins (Strongylocentrotus Purpuratus), Marilla Lippert, Maurice Codespoti Goodman, Nikki Adams

Biological Sciences

Organic compound-based “chemical” sunscreens dominate the commercial sunscreen market, but recent research has revealed the ingredients of these products are detrimental to the health of marine organisms. This revelation has led to increased popularity of mineral-based “physical” sunscreens, primarily containing zinc-oxide (ZnO), as environmentally safe alternatives. While they are marketed as environmentally safe, these claims are largely untested, and it is important to consider potential effects of ZnO-based sunscreens on the development of marine organisms. Though Zn is a necessary micronutrient in the ocean, excess Zn is released into marine environments from anthropogenic sources has negative effects on marine life. …


Body Composition Of Female Collegiate Track And Field Athletes, Adelaide Cooke May 2020

Body Composition Of Female Collegiate Track And Field Athletes, Adelaide Cooke

Biological Sciences

The aim of this study is to see if there is a correlation between an athlete's body compostion and the demands of their different track and field events. Track and field is arugably the most diverse when it comes to body types in a single sport, with distance runners tending to be leaner and smaller and throwers more muscular and larger. However, most data collected is not female specfic. Thirty-one female track and field athletes were asked to take part in a series of physical measurements, which included recording their height, weight, percent body fat, and muscle mass. They were …


Sensing Ribonuclease H Activity With Dna Nanoswitches, Ruju Trivedi May 2020

Sensing Ribonuclease H Activity With Dna Nanoswitches, Ruju Trivedi

Biological Sciences

Ribonuclease H (RNase H) is a damage-repair protein and ribonuclease that specifically catalyzes the hydrolysis of RNA in an RNA/DNA duplex and breaks down RNA/DNA junctions. It plays an important role in a variety of biological processes including DNA replication, DNA repair, and transcription. It is also pivotal in anti-HIV drug development and the analysis of cellular processes and has been shown to be a potential therapeutic target for various neoplastic diseases. This thesis discusses a unique assay based on DNA nanoswitches to detect RNase H levels and activity. The assay is based on conformational changes of DNA nanoswitches in …


Glutamine Antagonist 6-Diazo-5-Oxo-L-Norleucine, A Hyaluronan Synthesis Inhibitor, Slows Triple Negative Breast Cancer Growth, Le Gia Cat Pham May 2020

Glutamine Antagonist 6-Diazo-5-Oxo-L-Norleucine, A Hyaluronan Synthesis Inhibitor, Slows Triple Negative Breast Cancer Growth, Le Gia Cat Pham

Biological Sciences

Triple-negative breast cancers (TNBC) are the most aggressive subtype of breast cancer with few treatment options and poor outcomes. TNBCs are characterized by elevations in hexosamine biosynthetic pathway (HBP) enzyme expression, hyaluronan synthase 2 (HAS2) expression and hyaluronan (HA) production. Glutamine is an important substrate for HA production via the HBP. 6-diazo-5-oxo-L-norleucine (DON) is a well-known glutamine antagonist with validated antitumoral efficacy. This project examined the effects of DON on HA production and energy metabolism in TNBC cells. We examined the effect of DON treatment on Hs578T cells, which represent the mesenchymal stem-like subtype of TNBC. We specifically analyzed the …


Direct Evidence Of Missing Mepsps Using Ca2-Sensor Imaging, Petar Gajic May 2020

Direct Evidence Of Missing Mepsps Using Ca2-Sensor Imaging, Petar Gajic

Biological Sciences

Following an action potential in the presynaptic neuron there is evoked release of neurotransmitter into the synapse which activates ionotropic transmembrane receptors on the postsynaptic membrane that cause depolarizations in voltage that get recorded as excitatory postsynaptic potentials (EPSPs). In the absence of an action potential there is spontaneous release of neurotransmitter that postsynaptically gets recorded as miniature excitatory postsynaptic potentials (mEPSPs). According to the quantal hypothesis, postulated by Bernard Katz, the mEPSPs are allor- none changes in potential caused by a single quantum of neurotransmitter, which when added up create EPSPs. Following studies have found that these two modes …


Optical Activation Of Gaba Release From D2-Medium Spiny Neurons, Nurat Affinnih Apr 2020

Optical Activation Of Gaba Release From D2-Medium Spiny Neurons, Nurat Affinnih

Biological Sciences

Medium spiny neurons (MSNs) make up more than 95% of the cells in the striatum and therefore represent the main structures for specific information processing in the striatum. MSNs can be separated into two sub-populations based on the type of dopamine receptor they express and their target region. Roughly one-half of all MSNs express D1 dopamine receptors and send information to the substantia nigra pars compacta (SNc) and are called D1-MSNs. D1-MSNs are responsible for promoting movement execution. The other sub-population of MSNs expresses D2 dopamine receptors and for this reason, they are called D2-MSNs. D2-MSNs send information to the …


Heavy Metal Dissolution Mechanisms From Electrical Industrial Sludge, Viraj Gunarathne, Anushka Upamali Rajapaksha, Meththika Vithanage, Nadeesh Adassooriya, Asitha Cooray, Sudantha Liyanage, Bandunee Athapattu, Nishanta Rajakaruna, Avanthi Deshani Igalavithana, Deyi Hou, Daniel S. Alessi, Yong Sik Ok Dec 2019

Heavy Metal Dissolution Mechanisms From Electrical Industrial Sludge, Viraj Gunarathne, Anushka Upamali Rajapaksha, Meththika Vithanage, Nadeesh Adassooriya, Asitha Cooray, Sudantha Liyanage, Bandunee Athapattu, Nishanta Rajakaruna, Avanthi Deshani Igalavithana, Deyi Hou, Daniel S. Alessi, Yong Sik Ok

Biological Sciences

In this paper, we investigate the release of heavy metals from sludge produced from an electrical industry using both organic and inorganic acids. Single and sequential extractions were conducted to assess heavy metals in different phases of the sludge. Metal release from sludge was investigated in the presence of three inorganic acids (nitric, sulfuric, and phosphoric) and three organic acids (acetic, malic, and citric) at concentrations ranging from 0.1 to 2.0 mol L−1. Sequential extraction indicated the presence of Cu primarily in the carbonate fraction, Pb in the residual fraction, and Ni in the FeMn oxide fraction. The cumulative release …


Heavy Metal-Induced Oxidative Stress On Seed Germination And Seedling Development: A Critical Review, Mihiri Seneviratne, Nishanta Rajakaruna, Muhammad Rizwan, H. M. S. P. Madawala, Yong Sik Ok, Meththika Vithanage Aug 2019

Heavy Metal-Induced Oxidative Stress On Seed Germination And Seedling Development: A Critical Review, Mihiri Seneviratne, Nishanta Rajakaruna, Muhammad Rizwan, H. M. S. P. Madawala, Yong Sik Ok, Meththika Vithanage

Biological Sciences

Heavy metal contamination in soils can influence plants and animals, often leading to toxicosis. Heavy metals can impact various biochemical processes in plants, including enzyme and antioxidant production, protein mobilization and photosynthesis. Hydrolyzing enzymes play a major role in seed germination. Enzymes such as acid phosphatases, proteases and α-amylases are known to facilitate both seed germination and seedling growth via mobilizing nutrients in the endosperm. In the presence of heavy metals, starch is immobilized and nutrient sources become limited. Moreover, a reduction in proteolytic enzyme activity and an increase in protein and amino acid content can be observed under heavy …


The Effects Of Edaphic And Climatic Factors On Secondary Lichen Chemistry: A Case Study Using Saxicolous Lichens, Alexander Paukov, Anzhelika Teptina, Maria Morozova, Ekaterina Kruglova, Sergio E. Favero-Longo, Cora Bishop, Nishanti Rajakaruna Jun 2019

The Effects Of Edaphic And Climatic Factors On Secondary Lichen Chemistry: A Case Study Using Saxicolous Lichens, Alexander Paukov, Anzhelika Teptina, Maria Morozova, Ekaterina Kruglova, Sergio E. Favero-Longo, Cora Bishop, Nishanti Rajakaruna

Biological Sciences

Diversity of secondary lichen metabolites and their relationship to substrate and environmental parameters were studied in saxicolous lichens in the Middle and South Urals of Russia. Atranorin, usnic acid, gyrophoric acid, zeorin, norstictic acid, antraquinones and stictic acid were found in 73, 42, 41, 37, 36, 35 and 32 species, respectively, of 543 taxa collected. One hundred and ninety six species (i.e., 36% of total species documented) contained no secondary metabolites. Spectra of secondary metabolites of crustose lichens varied on different rock types, while in fruticose and foliose groups only those species without lichen acids were dependent on the substrate …


Tropic Transfer And Bioaccumulation Of Lead Along Soil-Plant-Aphid-Ladybird Food Chain, Mohod Irfan Naikoo, Mudasir Ifran Dar, Fareed Ahmad Khan, Fariha Raghib, N. Rajakaruna Jun 2019

Tropic Transfer And Bioaccumulation Of Lead Along Soil-Plant-Aphid-Ladybird Food Chain, Mohod Irfan Naikoo, Mudasir Ifran Dar, Fareed Ahmad Khan, Fariha Raghib, N. Rajakaruna

Biological Sciences

Lead (Pb) contamination of agroecosystems is a serious issue as Pb is a persistent pollutant that is retained in soil for long, causing toxicities to organisms. This study examines biotransfer of Pb from soils treated with different concentrations of Pb through a broad bean (Vicia faba L.)–aphid (Aphis fabae Scop.)–ladybird (Coccinella transversalis Fabricius) food chain and its consequent inference for natural biological control, the ladybird. The soil was amended with Pb at the rates of 0, 25, 50, 75 and 100 mg kg−1(w/w). The amount of Pb in plant, aphid and ladybird increased in a dose-dependent manner …


Influence Of Soil Water Content And Soil Amendments On Trace Metal Release And Seedling Growth In Serpentine Soil, Viraj Gunarathne, Nishanta Rajakaruna, Udaya Gunarathne, Jayanta Kumar Biswas, Zach A. Raposo, Meththika Vithanage Jun 2019

Influence Of Soil Water Content And Soil Amendments On Trace Metal Release And Seedling Growth In Serpentine Soil, Viraj Gunarathne, Nishanta Rajakaruna, Udaya Gunarathne, Jayanta Kumar Biswas, Zach A. Raposo, Meththika Vithanage

Biological Sciences

This study was conducted to evaluate the synergistic effects of organic amendments and soil water status on trace metal release from serpentine soil.


Availability Of Microtrash Materials And Selectivity By California Condors, Marie G. Solis Jun 2019

Availability Of Microtrash Materials And Selectivity By California Condors, Marie G. Solis

Biological Sciences

California condors consume non-food items, including anthropogenic waste, and provision it to their young. Consuming “microtrash” can cause mortality, especially in nestlings. There are several hypotheses explaining why condors might consume microtrash. These hypotheses assume condors exhibit a preference for the type of material. Therefore, we test the assumption that when California condors take microtrash, they display material selectivity. We did this by sampling microtrash from roadside pullouts in the Los Padres National Forest. Those samples were compared to condor necropsy and nest microtrash data, categorized by material type: glass, plastic, metal, and other. We find that in our analysis …


Investigating The Effects Of Intrahippocampal Glucose Administration On Spatial Working Memory In Rats, Jeremy Carter May 2019

Investigating The Effects Of Intrahippocampal Glucose Administration On Spatial Working Memory In Rats, Jeremy Carter

Biological Sciences

Insulin is a peptide hormone released by beta pancreatic cells . Insulin’s best-known function is to regulate absorption of glucose into peripheral tissue: this occurs via activation of the phosphoinositide 3-kinase (PI3K) signaling cascade and subsequent translocation of glucose transporter 4 (GLUT4) to the cell surface. This canonical peripheral insulin signaling pathway appears to exist in essentially identical form within the central nervous system (CNS), so that insulin promotes entry of glucose into neural cells and subsequent increased metabolism. In order to maintain proper function, insulin-responsive hippocampal neurons and glia require glucose metabolism; a catabolic energy-yielding process that requires insulin …


The Efficacy Of Ventral Pallidum- Deep Brain Stimulation In Rat Models Of Epilepsy, Fu Yee Chua May 2019

The Efficacy Of Ventral Pallidum- Deep Brain Stimulation In Rat Models Of Epilepsy, Fu Yee Chua

Biological Sciences

Antiepileptic drugs have been a primary option for patients with epilepsy worldwide, however, about one-third of patients do not respond to pharmacotherapy. For these individuals, resective surgery can be performed but seizures are still reported in some cases. With that in mind, neuromodulation or deep brain stimulation (DBS) is a plausible alternative to provide seizure freedom for refractory individuals. Vagus nerve stimulation (VNS), anterior thalamus DBS and responsive neurostimulation (RNS) are FDA approved as neuromodulatory approaches for epilepsy. They reduce and delay seizures but do not prevent or abolish seizures. In the previous study, the Shin lab showed that DBS …


Rna Secondary Structure Of 3’Utr Regulates Translation Control, M. Grace Hren May 2019

Rna Secondary Structure Of 3’Utr Regulates Translation Control, M. Grace Hren

Biological Sciences

According to the central dogma of biology, DNA is transcribed into mRNA. This mRNA is then translated into a protein. Translation of mRNA into protein is extremely precise, and as such is controlled by many different factors, both spatially and temporally. This phenomenon is known as translation control. Many times, this regulation is influenced by secondary structures, often in the form of stem loops on the mRNA. These secondary structures found on mRNA, specifically in the 3’Untranslated Region (3’UTR) of mRNA, can influence cellular gene expression. These genes can be upregulated or down regulated, depending on stem loop function. When …


An Assessment Of Combinatorial Transcription Factor Activity At P53 Enhancer Elements, Sylvia Kuang May 2019

An Assessment Of Combinatorial Transcription Factor Activity At P53 Enhancer Elements, Sylvia Kuang

Biological Sciences

Certain non-coding DNA sequences in the eukaryotic genome regulate gene expression. These non-coding regulatory regions, including promoters and enhancers, are controlled by the binding of multiple transcription factors which act together to regulate gene transcription. The number of potential transcription factor combinations regulating any gene presents a massive experimental challenge. One well-known transcription factor, p53, activates multiple transcription pathways involved in tumor suppression, primarily through engagement with enhancers. p53 is one member of a paralogous transcription factor family, which includes the factor p63. Whereas p53 is involved in tumor suppression, p63 is a transcription factor responsible for maintaining epithelial cell …


Long-Term Phytoremediating Abilities Of Dalbergia Sissoo Roxb. (Fabaceae), Saqib Ul Kalam, Fauzia Naushin, Fareed Ahmad Khan, Nishanta Rajakaruna Jan 2019

Long-Term Phytoremediating Abilities Of Dalbergia Sissoo Roxb. (Fabaceae), Saqib Ul Kalam, Fauzia Naushin, Fareed Ahmad Khan, Nishanta Rajakaruna

Biological Sciences

The boom of tanneries in north India has converted the river Ganga into a waste dumping stream. The tanneries discharge their heavy metal-rich effluents into the river. Tissues of two-year-old tree saplings of Dalbergia sissoo, soil sediments and river water samples were collected from three sites along the river Ganga at Jajmau, Kanpur. Site-1 was located 1 km upstream from the point of discharge of the effluents of the tanneries, Site-2 was close to the source point, and Site-3 was about 1 km downstream from the source point. Accumulation of Cu, Cr and Ni in leaves, bark, wood growth rings, …


The Effect Of The Zika Virus On Rna Stress Granule Components, Nina Williams Dec 2018

The Effect Of The Zika Virus On Rna Stress Granule Components, Nina Williams

Biological Sciences

In recent years, Zika virus (ZIKV) has taken over mainstream media. It captivated the world with the images of microcephaly babies born to infected mothers and the appearance of Guillain-Barré syndrome emerging from infected adults. ZIKV is transmitted by the Aedes mosquito. This virus is composed of a single-stranded positive-sense RNA genome that belongs to the Flaviviridae family. Our long-term goal is to understand the mechanisms in which the virus subverts the host organism’s translation machinery by modulation of RNA stress granules (SGs). Stress granules are RNA-protein complexes found in the cytoplasm that form when the cell is exposed to …


Climactic Niche Model For Overwintering Monarch Butterflies In A Topographically Complex Region Of California, Ashley Fisher, Kiana Saniee, Charis Van Der Heide, Jessica Griffiths, Daniel Meade, Francis X. Villablanca Nov 2018

Climactic Niche Model For Overwintering Monarch Butterflies In A Topographically Complex Region Of California, Ashley Fisher, Kiana Saniee, Charis Van Der Heide, Jessica Griffiths, Daniel Meade, Francis X. Villablanca

Biological Sciences

We use climatic conditions that are associated with known monarch butterfly overwintering groves in California to build a Maxent model, and focus on the fine scale probability of overwintering grove occurrence in a topographically complex region of the state (Santa Barbara County). Grove locations are known from recent and historical surveys and a long-term citizen science database. The climatic niche model performs well, predicting that overwintering habitat is most likely to occur along the coast and at low elevations, as shown by empirical data. We then use climatic variables in conjunction with climate change scenarios to model the future location …


Intracanopy Adjustment Of Leaf-Level Thermal Tolerance Is Associated With Microclimatic Variation Across The Canopy Of A Desert Tree (Acacia Papyrocarpa), Ellen M. Curtis, Charles A. Knight, Andrea Leigh Oct 2018

Intracanopy Adjustment Of Leaf-Level Thermal Tolerance Is Associated With Microclimatic Variation Across The Canopy Of A Desert Tree (Acacia Papyrocarpa), Ellen M. Curtis, Charles A. Knight, Andrea Leigh

Biological Sciences

Tree crowns are spatially heterogeneous, sometimes resulting in significant variation in microclimate across the canopy, particularly with respect to temperature. Yet it is not known whether such localised temperature variation equates to intracanopy variation in leaf-level physiological thermal tolerance. Here, we studied whether microclimate variation across the canopy of a dominant desert tree equated to localised variation in leaf thermal thresholds (T50) among four canopy positions: upper south, upper north, lower south, lower north. Principal component analysis was used to generate a composite climatic stress variable (CSTRESS) from canopy temperature, vapour pressure deficit, and …


Inducing Ni Sensitivity In The Ni Hyperaccumulator Plant Alyssum Inflatum Nyárády (Brassicaceae) By Transforming With Cax1, A Vacuolar Membrane Calcium Transporter, Rasoul Ghasemi, Hoorieh Share, Roza Sharif, Robert S. Boyd, Nishanta Rajakaruna Jul 2018

Inducing Ni Sensitivity In The Ni Hyperaccumulator Plant Alyssum Inflatum Nyárády (Brassicaceae) By Transforming With Cax1, A Vacuolar Membrane Calcium Transporter, Rasoul Ghasemi, Hoorieh Share, Roza Sharif, Robert S. Boyd, Nishanta Rajakaruna

Biological Sciences

The importance of calcium in nickel tolerance was studied in the nickel hyperaccumulator plant Alyssum inflatum by gene transformation of CAX1, a vacuolar membrane transporter that reduces cytosolic calcium. CAX1 from Arabidopsis thaliana with a CaMV35S promoter accompanying a kanamycin resistance gene was transferred into A. inflatum using Agrobacterium tumefaciens. Transformed calli were subcultured three times on kanamycin-rich media and transformation was confirmed by PCR using a specific primer for CAX1. At least 10 callus lines were used as a pool of transformed material. Both transformed and untransformed calli were treated with varying concentrations of either calcium (1–15 mM) or …


Sympatric Serpentine Endemic Monardella (Lamiaceae) Species Maintain Habitat Differences Despite Hybridization, Kathleen M. Kay, Suzie Woolhouse, Brett A. Smith, Nathaniel S. Pope, Nishanta Rajakaruna May 2018

Sympatric Serpentine Endemic Monardella (Lamiaceae) Species Maintain Habitat Differences Despite Hybridization, Kathleen M. Kay, Suzie Woolhouse, Brett A. Smith, Nathaniel S. Pope, Nishanta Rajakaruna

Biological Sciences

Ecological differentiation and genetic isolation are thought to be critical in facilitating coexistence between related species, but the relative importance of these phenomena and the interactions between them are not well understood. Here, we examine divergence in abiotic habitat affinity and the extent of hybridization and introgression between two rare species of Monardella (Lamiaceae) that are both restricted to the same serpentine soil exposure in California. Although broadly sympatric, they are found in microhabitats that differ consistently in soil chemistry, slope, rockiness and vegetation. We identify one active hybrid zone at a site with intermediate soil and above-ground characteristics, and …


Diversity And Functional Traits Of Lichens In Ultramafic Areas: A Literature Based Worldwide Analysis Integrated By Field Data At The Regional Scale, Sergio E. Favero-Longo, Enrica Matteucci, Paolo Giordani, Alexander G. Paukov, Nishanta Rajakaruna May 2018

Diversity And Functional Traits Of Lichens In Ultramafic Areas: A Literature Based Worldwide Analysis Integrated By Field Data At The Regional Scale, Sergio E. Favero-Longo, Enrica Matteucci, Paolo Giordani, Alexander G. Paukov, Nishanta Rajakaruna

Biological Sciences

While higher plant communities found on ultramafics are known to display peculiar characteristics, the distinguishability of any peculiarity in lichen communities is still a matter of contention. Other biotic or abiotic factors, rather than substrate chemistry, may contribute to differences in species composition reported for lichens on adjacent ultramafic and non-ultramafic areas. This work examines the lichen biota of ultramafics, at global and regional scales, with reference to species-specific functional traits. An updated world list of lichens on ultramafic substrates was analyzed to verify potential relationships between diversity and functional traits of lichens in different Köppen–Geiger climate zones. Moreover, a …


Biological Crusts Of Serpentine And Non-Serpentine Soils From The Barberton Greenstone Belt Of South Africa, Arthurita Venter, Stefan Siebert, Nishanta Rajakaruna, Sandra Barnard, Anatoliy Levanets, Arshad Ismail, Mushal Allam, Bianca Peterson, Tomasz Sanko May 2018

Biological Crusts Of Serpentine And Non-Serpentine Soils From The Barberton Greenstone Belt Of South Africa, Arthurita Venter, Stefan Siebert, Nishanta Rajakaruna, Sandra Barnard, Anatoliy Levanets, Arshad Ismail, Mushal Allam, Bianca Peterson, Tomasz Sanko

Biological Sciences

Climate and geography can influence biological soil crust (BSC) community composition, but local heterogeneity in variables such as soil characteristics or microclimate gradients can also impact cryptogamic diversity. Heavy metals and nutrient imbalances in serpentine soils are known to influence the distributions of higher plants, but cryptogamic species appear to be more tolerant of substrate. The aim of this study was to compare the cryptogamic composition of serpentine and non-serpentine soils by using integrative taxonomy, which combines morphological and DNA barcoding data, to determine how soil characteristics in combination with rainfall can influence BSC community composition. Samples from serpentine and …


Senecio Conrathii N.E.Br. (Asteraceae), A New Hyperaccumulator Of Nickel From Serpentinite Outcrops Of The Barberton Greenstone Belt, South Africa, Stefan Siebert, Nadine Carol Schutte, Stoffel Pieter Bester, Dennis Mmakgabo Komape, Nishanta Rajakaruna May 2018

Senecio Conrathii N.E.Br. (Asteraceae), A New Hyperaccumulator Of Nickel From Serpentinite Outcrops Of The Barberton Greenstone Belt, South Africa, Stefan Siebert, Nadine Carol Schutte, Stoffel Pieter Bester, Dennis Mmakgabo Komape, Nishanta Rajakaruna

Biological Sciences

Five nickel hyperaccumulators belonging to the Asteraceae are known from ultramafic outcrops in South Africa. Phytoremediation applications of the known hyperaccumulators in the Asteraceae, such as the indigenous Berkheya coddii Roessler, are well reported and necessitate further exploration to find additional species with such traits. This study targeted the most frequently occurring species of the Asteraceae on eight randomly selected serpentinite outcrops of the Barberton Greenstone Belt. Twenty species were sampled, including 12 that were tested for nickel accumulation for the first time. Although the majority of the species were excluders, the known hyperaccumulators Berkheya nivea N.E.Br. and B. zeyheri …


A Global Forum On Ultramafic Ecosystems: From Ultramafic Ecology To Rehabilitation Of Degraded Environments, Guillaume Echevarria, Alan J. M. Baker, Robert S. Boyd, Antony Van Der Ent, Takafumi Mizuno, Nishanta Rajakaruna, Shota Sakaguchi, Aida Bani May 2018

A Global Forum On Ultramafic Ecosystems: From Ultramafic Ecology To Rehabilitation Of Degraded Environments, Guillaume Echevarria, Alan J. M. Baker, Robert S. Boyd, Antony Van Der Ent, Takafumi Mizuno, Nishanta Rajakaruna, Shota Sakaguchi, Aida Bani

Biological Sciences

The 9th International Conference on Serpentine Ecology (ICSE) was held in Tirana and Pogradec (Albania) from June 5 to 9, 2017. More than 100 delegates from 29 countries around the world gathered to present their research on recent advances in: (i) ultramafic soils, (ii) biogeochemistry, (iii) diversity of ultramafic flora, microflora and fauna, (iv) ecophysiology of ultramafic-adapted organisms, (v) interactions between ultramafic organisms and their ecology, (vi) nature rehabilitation of degraded ultramafic environments (resulting from mining activities), and (vii) the production of bio-based metals through agromining technology. Additionally, the ICSE featured the first symposium on ultramafic aquatic ecology and ecotoxicology. …


Ultramafic Vegetation And Soils In The Circumboreal Region Of The Northern Hemisphere, Anzhelika Teptina May 2018

Ultramafic Vegetation And Soils In The Circumboreal Region Of The Northern Hemisphere, Anzhelika Teptina

Biological Sciences

The paper summarizes literature on climate, soil chemistry, vegetation and metal accumulation by plants found on ultramafic substrata in the circumboreal zone (sensu Takhtajan, Floristic regions of the world, 1986) of the Northern Hemisphere. We present a list of 50 endemic species and 18 ecotypes obligate to ultramafic soils from the circumboreal region of Holarctic, as well as 30 and 2 species of Ni and Zn hyperaccumulators, respectively. The number of both endemics and hyperaccumulators are markedly lower compared to that of the Mediterranean and tropical regions. The diversity of plant communities on ultramafics soils of the circumboral region is …


The Role Of Rck/P54 Enzymatic Activity During Hepatitis C Infection, Rachel E. Eager May 2018

The Role Of Rck/P54 Enzymatic Activity During Hepatitis C Infection, Rachel E. Eager

Biological Sciences

Hepatitis C virus (HCV) infected 30,500 people in the United States alone in 2014. As a positive-sense single-stranded RNA virus, the HCV genome facilitates translation and replication of the virus within the host cell. During infection, HCV subverts numerous host proteins to aid in viral production. One such protein is DDX6, a DEAD-box helicase that is associated with the decapping complex and microRNA Induced Silencing Complex (miRISC). Previous studies in our lab have shown that DDX6 is required for HCV expression. Specifically, DDX6 modulates the interaction of miR-122 with the HCV 5’ UTR and promotes stability and replication of the …