Open Access. Powered by Scholars. Published by Universities.®
- Discipline
-
- Ecology and Evolutionary Biology (51)
- Plant Sciences (38)
- Plant Biology (31)
- Biochemistry, Biophysics, and Structural Biology (24)
- Arts and Humanities (21)
-
- Biochemistry (18)
- Microbiology (18)
- Population Biology (18)
- Religion (17)
- Cell and Developmental Biology (16)
- Genetics and Genomics (16)
- Evolution (15)
- Behavior and Ethology (12)
- Cell Biology (12)
- Terrestrial and Aquatic Ecology (10)
- Environmental Microbiology and Microbial Ecology (8)
- Biomedical Engineering and Bioengineering (6)
- Engineering (6)
- Microbial Physiology (6)
- Ethics in Religion (5)
- Genetics (5)
- Molecular Genetics (4)
- Bacteriology (3)
- Biophysics (3)
- Genomics (3)
- Physical Sciences and Mathematics (3)
- Social and Behavioral Sciences (3)
- Anthropology (2)
- Keyword
-
- Biology (49)
- Bibliography (24)
- Genomics (23)
- Evolution (21)
- Cancer (20)
-
- Epigenetics (17)
- Cellular mechanotransduction (15)
- Microtubules (13)
- Development (12)
- Zebrafish (12)
- Diabetes (11)
- Genetics (11)
- Arabidopsis (10)
- Inflammation (10)
- Microbiome (10)
- Microbiota (10)
- DNA methylation (9)
- Hematopoiesis (9)
- Microglia (9)
- Cooperation (8)
- Ion channels (8)
- Macrophages (8)
- Mitochondria (8)
- RNA (8)
- Urinary tract infection (8)
- Antibiotic resistance (7)
- Arabidopsis thaliana (7)
- Bioinformatics (7)
- Community assembly (7)
- Immunotherapy (7)
- Publication Year
- Publication
- Publication Type
- File Type
Articles 121 - 150 of 1126
Full-Text Articles in Biology
Biology Department Publications: 2014, Sam Lindgren
Biology Department Publications: 2014, Sam Lindgren
Biology Department Bibliographies
This document is a noncomprehensive list of publications made by graduate students, post-doctoral researchers, and faculty members in the Biology Department in 2014. It indexes those publications available through major databases, and serves as an archival record of the Department’s robust scholarly contributions.
Biology Department Publications: 2017, Sam Lindgren
Biology Department Publications: 2017, Sam Lindgren
Biology Department Bibliographies
This document is a noncomprehensive list of publications made by graduate students, post-doctoral researchers, and faculty members in the Biology Department in 2017. It indexes those publications available through major databases, and serves as an archival record of the Department’s robust scholarly contributions.
Biology Department Publications: 2009, Sam Lindgren
Biology Department Publications: 2009, Sam Lindgren
Biology Department Bibliographies
This document is a noncomprehensive list of publications made by graduate students, post-doctoral researchers, and faculty members in the Biology Department in 2009. It indexes those publications available through major databases, and serves as an archival record of the Department’s robust scholarly contributions.
Biology Department Publications: 2005, Sam Lindgren
Biology Department Publications: 2005, Sam Lindgren
Biology Department Bibliographies
This document is a noncomprehensive list of publications made by graduate students, post-doctoral researchers, and faculty members in the Biology Department in 2005. It indexes those publications available through major databases, and serves as an archival record of the Department’s robust scholarly contributions.
Biology Department Publications: 2011, Sam Lindgren
Biology Department Publications: 2011, Sam Lindgren
Biology Department Bibliographies
This document is a noncomprehensive list of publications made by graduate students, post-doctoral researchers, and faculty members in the Biology Department in 2011. It indexes those publications available through major databases, and serves as an archival record of the Department’s robust scholarly contributions.
Biology Department Publications: 2007, Sam Lindgren
Biology Department Publications: 2007, Sam Lindgren
Biology Department Bibliographies
This document is a noncomprehensive list of publications made by graduate students, post-doctoral researchers, and faculty members in the Biology Department in 2007. It indexes those publications available through major databases, and serves as an archival record of the Department’s robust scholarly contributions.
Biology Department Publications: 2022, Sam Lindgren
Biology Department Publications: 2022, Sam Lindgren
Biology Department Bibliographies
This document is a noncomprehensive list of publications made by graduate students, post-doctoral researchers, and faculty members in the Biology Department in 2022. It indexes those publications available through major databases, and serves as an archival record of the Department’s robust scholarly contributions.
Biology Department Publications: 2018, Sam Lindgren
Biology Department Publications: 2018, Sam Lindgren
Biology Department Bibliographies
This document is a noncomprehensive list of publications made by graduate students, post-doctoral researchers, and faculty members in the Biology Department in 2018. It indexes those publications available through major databases, and serves as an archival record of the Department’s robust scholarly contributions.
Biology Department Publications: 2020, Sam Lindgren
Biology Department Publications: 2020, Sam Lindgren
Biology Department Bibliographies
This document is a noncomprehensive list of publications made by graduate students, post-doctoral researchers, and faculty members in the Biology Department in 2020. It indexes those publications available through major databases, and serves as an archival record of the Department’s robust scholarly contributions.
Biology Department Publications: 2006, Sam Lindgren
Biology Department Publications: 2006, Sam Lindgren
Biology Department Bibliographies
This document is a noncomprehensive list of publications made by graduate students, post-doctoral researchers, and faculty members in the Biology Department in 2006. It indexes those publications available through major databases, and serves as an archival record of the Department’s robust scholarly contributions.
Biology Department Publications: 2016, Sam Lindgren
Biology Department Publications: 2016, Sam Lindgren
Biology Department Bibliographies
This document is a noncomprehensive list of publications made by graduate students, post-doctoral researchers, and faculty members in the Biology Department in 2016. It indexes those publications available through major databases, and serves as an archival record of the Department’s robust scholarly contributions.
Biology Department Publications: 2019, Sam Lindgren
Biology Department Publications: 2019, Sam Lindgren
Biology Department Bibliographies
This document is a noncomprehensive list of publications made by graduate students, post-doctoral researchers, and faculty members in the Biology Department in 2019. It indexes those publications available through major databases, and serves as an archival record of the Department’s robust scholarly contributions.
Biology Department Publications: 2012, Sam Lindgren
Biology Department Publications: 2012, Sam Lindgren
Biology Department Bibliographies
This document is a noncomprehensive list of publications made by graduate students, post-doctoral researchers, and faculty members in the Biology Department in 2012. It indexes those publications available through major databases, and serves as an archival record of the Department’s robust scholarly contributions.
Biology Department Publications: 2015, Sam Lindgren
Biology Department Publications: 2015, Sam Lindgren
Biology Department Bibliographies
This document is a noncomprehensive list of publications made by graduate students, post-doctoral researchers, and faculty members in the Biology Department in 2015. It indexes those publications available through major databases, and serves as an archival record of the Department’s robust scholarly contributions.
Biology Department Publications: 2010, Sam Lindgren
Biology Department Publications: 2010, Sam Lindgren
Biology Department Bibliographies
This document is a noncomprehensive list of publications made by graduate students, post-doctoral researchers, and faculty members in the Biology Department in 2010. It indexes those publications available through major databases, and serves as an archival record of the Department’s robust scholarly contributions.
Biology Department Publications: 2013, Sam Lindgren
Biology Department Publications: 2013, Sam Lindgren
Biology Department Bibliographies
This document is a noncomprehensive list of publications made by graduate students, post-doctoral researchers, and faculty members in the Biology Department in 2013. It indexes those publications available through major databases, and serves as an archival record of the Department’s robust scholarly contributions.
Biology Department Publications: 2023, Sam Lindgren
Biology Department Publications: 2023, Sam Lindgren
Biology Department Bibliographies
This document is a non-comprehensive list of publications made by graduate students, post-doctoral researchers, and faculty members in the Biology Department in 2023. It indexes those publications available through PubMed and Scopus, and serves as an archival record of the Department’s robust scholarly contributions.
Biology Department Publications: 2008, Sam Lindgren
Biology Department Publications: 2008, Sam Lindgren
Biology Department Bibliographies
This document is a noncomprehensive list of publications made by graduate students, post-doctoral researchers, and faculty members in the Biology Department in 2008. It indexes those publications available through major databases, and serves as an archival record of the Department’s robust scholarly contributions.
Biology Department Publications: 2021, Sam Lindgren
Biology Department Publications: 2021, Sam Lindgren
Biology Department Bibliographies
This document is a noncomprehensive list of publications made by graduate students, post-doctoral researchers, and faculty members in the Biology Department in 2021. It indexes those publications available through major databases, and serves as an archival record of the Department’s robust scholarly contributions.
Sleep Restores An Optimal Computational Regime In Cortical Networks, Yifan Xu
Sleep Restores An Optimal Computational Regime In Cortical Networks, Yifan Xu
Arts & Sciences Graduate Student Theses and Dissertations
Computation within the brain necessitates consistency and robustness, as no complex system can function effectively without these fundamental attributes. However, maintaining this robustness requires active efforts due to the inevitable perturbations (Turrigiano & Nelson, 2004). To unlock the unifying principle of how brain works, it is essential to identify an optimal set point that the system strives to maintain and restore, ensuring stability and functionality. Our lab recently demonstrated that cortical dynamics are homeostatically organized around criticality (Ma et al., 2019), a computational regime that optimizes information processing, such as information capacity and dynamic range (Shew & Plenz, 2013). This …
Germline Genetic Determinates Of Cancer And Pre-Malignant Conditions, Jie Liu
Germline Genetic Determinates Of Cancer And Pre-Malignant Conditions, Jie Liu
Arts & Sciences Graduate Student Theses and Dissertations
Cancer is a genetic disease stemming from a combination of inherited and acquired mutations. In my thesis, we sought to characterize how germline genetic variation affects acquired clonal expansions in normal tissues and its progression to malignancy. In Chapter 2, we studied the impact of germline genetic variation on clonal hematopoiesis (CH) in 731,835 individuals. We identified 22 novel CH predisposition genes, most of which predispose to CH driven by specific mutational events. CH predisposition genes contribute to unique somatic landscapes reflecting the influence of germline genetic backdrop on gene-specific CH fitness. Correspondingly, somatic-germline interactions influence the risk of CH …
Developing Tools To Study The Effect Of The Mechanical Environment On Plant Cell Growth And Morphogenesis, Ryan Calcutt
Developing Tools To Study The Effect Of The Mechanical Environment On Plant Cell Growth And Morphogenesis, Ryan Calcutt
Arts & Sciences Graduate Student Theses and Dissertations
Mechanical forces are omnipresent in life on Earth and responses to force can be found across all three domains of life. The colonization of land by plants approximately 500 million years ago, an event that shaped life on Earth as we know it, involved adaptation from a relatively homogeneous fluid mechanical environment to a highly heterogeneous and mechanically diverse terrestrial environment. Evolution of multicellularity would present new mechanical challenges for land plants, not only from externally generated forces, but also from mechanical linkage to neighboring cells through the cell wall. Coordination of cell growth and an indeterminate body plan requires …
Island Hopping In The Tropics: Conservation Genetics, Speciation, And Biogeography In The Iconic Flowering Plant Group Hibiscus Sect. Lilibiscus, Brock Mashburn
Island Hopping In The Tropics: Conservation Genetics, Speciation, And Biogeography In The Iconic Flowering Plant Group Hibiscus Sect. Lilibiscus, Brock Mashburn
Arts & Sciences Graduate Student Theses and Dissertations
Islands have played a crucial role in evolutionary biology, providing key insights for both Charles Darwin and Alfred Russel Wallace in formulating their theories of evolution. The development of Island Biogeography Theory and the General Dynamic Model of oceanic island biogeography have formed the theoretical foundation of island studies over the last sixty years, leading to substantial advancements in our understanding of biodiversity evolution. Despite their critical value for evolutionary theory, islands face unprecedented ecological collapse, with species on islands facing significantly higher extinction rates than on continents. The island extinction crisis highlights the need for integrating conservation perspectives into …
Functional Genomics Approaches To Understanding The Impact Of Common And Rare Risk Variants On Microglia Function In Neurodegenerative Diseases, Shih-Feng You
Arts & Sciences Graduate Student Theses and Dissertations
Genome-wide association studies (GWAS) have identified more than 70 genetic loci that are linked to Alzheimer disease (AD) risk. Many of these risk genes are involved in microglial function, including MS4A4A, TREM2, and PLD3, suggesting a relationship between microglial phagocytosis, metabolism, inflammation, and AD pathogenesis. However, the mechanisms by which AD risk genes alter microglia function and contribute to disease remains inadequately explored. In this dissertation, I leveraged functional genomics methods to understand the impact of MS4A4A, TREM2, and PLD3 on microglia function in stem cell and mouse models as well as human brain tissue. MS4A4A is a microglial gene …
An Intronic Regulatory Element Limits Tcf7 Expression In Natural Killer Cells, Matthew Vincent Mccullen
An Intronic Regulatory Element Limits Tcf7 Expression In Natural Killer Cells, Matthew Vincent Mccullen
Arts & Sciences Graduate Student Theses and Dissertations
To provide protection against a broad spectrum of threats, the immune system must give rise to a diverse range of cell types each with specialized roles in host defense. Transcriptional regulation is achieved by interactions between transcription factors and non-coding cis-regulatory DNA elements such as promoters and enhancers. One of the most important transcription factors in lymphocyte development and function is TCF1 (encoded by the Tcf7 gene). TCF1 is required for the efficient development of both innate lymphocytes, such as NK cells, as well as adaptive T cells. TCF1 also regulates the functional abilities of these cell types, such as …
Predicting Cell Fate Using Single-Cell State And Lineage Information, Emily Grace Butka
Predicting Cell Fate Using Single-Cell State And Lineage Information, Emily Grace Butka
Arts & Sciences Graduate Student Theses and Dissertations
Humans begin as a single cell, with successive cell divisions ultimately giving rise to a complex organism comprised of innumerable highly specialized cells. In this process, cells begin as pluripotent stem cells and slowly shift towards these highly specialized identities. Several technological innovations have enabled scientists to measure and track many aspects of a single cell’s identity as these divisions occur, at increasingly large scale and rapidly declining cost. As a result, our fundamental understanding of cell identity has grown to encompass several layers of cellular dynamics, including aspects that are both intrinsic and extrinsic, transient and permanent, active and …
Insights From Open Conformations Of Ecmsck, Htrpv4, And Hhcn1 Into The Structural Basis Of Ligand-Regulated Ion Channel Gating, Jonathan Mount
Insights From Open Conformations Of Ecmsck, Htrpv4, And Hhcn1 Into The Structural Basis Of Ligand-Regulated Ion Channel Gating, Jonathan Mount
Arts & Sciences Graduate Student Theses and Dissertations
Ion channels are found in all domains of life and play fundamental roles in cellular signaling and response to environmental cues. The ability to accommodate the selective and rapid passage of ions across a cell membrane is conferrable by a myriad of protein folds with no singular one-size-fits-all approach. With the advent of the cryo-EM resolution revolution, substantial interest has developed for determining the molecular structures of conformational states that correspond to conductive and nonconductive forms of ion channels. By gaining insight into the structural mechanisms for ion channel gating, we can potentially reveal binding pockets for targeted small molecule …
Insulin-Independent Regulation Of Type 1 Diabetes Via Large Brown Adipocyte-Secreted Proteins And The Novel Glucagon Regulator, Nidogen2, Jeongmin Lee
Arts & Sciences Graduate Student Theses and Dissertations
Current treatments for type 1 diabetes (T1D) focus on insulin replacement. We demonstrate the therapeutic potential of a secreted protein fraction from embryonic brown adipose tissue (BAT), independent of insulin. The large molecular weight secreted fraction mediates insulin receptor-dependent recovery of euglycemia in a T1D animal model, nonobese diabetic (NOD) mice, by suppressing glucagon secretion. This fraction also promotes white adipocyte differentiation and browning, maintains healthy BAT, and enhances glucose uptake in adipose tissue, skeletal muscle, and liver. From this fraction, we identify nidogen-2 as a critical BAT-secreted protein that reverses hyperglycemia in NOD mice, inhibits glucagon secretion from pancreatic …
Gnotobiotic Mouse Models For Characterizing The Role Of The Microbiota On Undernutrition And Early Postnatal Brain Development, Alexandra Elizabeth Byrne
Gnotobiotic Mouse Models For Characterizing The Role Of The Microbiota On Undernutrition And Early Postnatal Brain Development, Alexandra Elizabeth Byrne
Arts & Sciences Graduate Student Theses and Dissertations
Undernutrition is a serious global health challenge; it accounts for nearly half of all mortality for children under the age of 5. Worse, undernutrition is compounded by intergenerational inheritance and can be transmitted from mother to offspring. The burden of undernutrition is unequally distributed around the world, with South Asia and Sub-Saharan Africa accounting for almost 60% of the global childhood stunting. Undernutrition is detrimental to many aspects of development, including long-term deficits in neurodevelopment, and current interventions rarely ameliorate long-term cognitive and motor deficits. Therefore, other causes of undernutrition need to be elucidated in order to treat this epidemic …
Investigation Of Photoperiodic Control Of Hypocotyl 1’S Role In Promoting Phytochrome B-Photobody Phase Separation, Sarah Anne Pardi
Investigation Of Photoperiodic Control Of Hypocotyl 1’S Role In Promoting Phytochrome B-Photobody Phase Separation, Sarah Anne Pardi
Arts & Sciences Graduate Student Theses and Dissertations
Light is arguably the most important environmental stimuli for all of plant growth and survival. Not only does light serve as an energy source via photosynthesis, it also serves as a signal for developmental programming. Plants perceive light through light-responsive proteins termed photoreceptors. Phytochromes are conserved red/far-red light photoreceptors. In the model plant Arabidopsis thaliana (thale cress), phytochrome B (phyB) is the primary red light photoreceptor. PhyB is involved in regulating almost all developmental processes throughout the plant’s life cycle, from seedling germination to flowering. In response to red light, phytochromes photoconvert to a biologically active form, transport from the …