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Articles 391 - 420 of 558
Full-Text Articles in Biology
Diverse Deep-Sea Anglerfishes Share A Genetically Reduced Luminous Symbiont That Is Acquired From The Environment, Lydia Baker, Lindsay L. Freed, Cole Easson, Jose Lopez, Dante Fenolio, Tracey Sutton, Spencer Nyholm, Tory Hendry
Diverse Deep-Sea Anglerfishes Share A Genetically Reduced Luminous Symbiont That Is Acquired From The Environment, Lydia Baker, Lindsay L. Freed, Cole Easson, Jose Lopez, Dante Fenolio, Tracey Sutton, Spencer Nyholm, Tory Hendry
Biology Faculty Articles
Deep-sea anglerfishes are relatively abundant and diverse, but their luminescent bacterial symbionts remain enigmatic. The genomes of two symbiont species have qualities common to vertically transmitted, host-dependent bacteria. However, a number of traits suggest that these symbionts may be environmentally acquired. To determine how anglerfish symbionts are transmitted, we analyzed bacteria-host codivergence across six diverse anglerfish genera. Most of the anglerfish species surveyed shared a common species of symbiont. Only one other symbiont species was found, which had a specific relationship with one anglerfish species, Cryptopsaras couesii. Host and symbiont phylogenies lacked congruence, and there was no statistical support …
Characterization Of The Microbiome And Bioluminescent Symbionts Across Life Stages Of Ceratioid Anglerfishes Of The Gulf Of Mexico, Lindsay L. Freed, Cole Easson, Lydia Baker, D. Fenolio, Tracey Sutton, Yasmin Khan, Patricia Blackwelder, Tory Hendry, Jose Lopez
Characterization Of The Microbiome And Bioluminescent Symbionts Across Life Stages Of Ceratioid Anglerfishes Of The Gulf Of Mexico, Lindsay L. Freed, Cole Easson, Lydia Baker, D. Fenolio, Tracey Sutton, Yasmin Khan, Patricia Blackwelder, Tory Hendry, Jose Lopez
Biology Faculty Articles
The interdependence of diverse organisms through symbiosis reaches even the deepest parts of the oceans. As part of the DEEPEND project (deependconsortium.org) research on deep Gulf of Mexico biodiversity, we profiled the bacterial communities (‘microbiomes’) and luminous symbionts of 36 specimens of adult and larval deep-sea anglerfishes of the suborder Ceratioidei using 16S rDNA. Transmission Electron Microscopy was used to characterize the location of symbionts in adult light organs (esca). Whole larval microbiomes, and adult skin and gut microbiomes, were dominated by bacteria in the genera Moritella and Pseudoalteromonas genera. 16S rDNA sequencing results from adult fishes corroborate …
"The Dead Shall Be Raised": Multidisciplinary Analysis Of Human Skeletons Reveals Complexity In 19th Century Immigrant Socioeconomic History And Identity In New Haven, Connecticut, Gary P. Aronsen, Lars Fehren-Schmitz, John Krigbaum, George D. Kamenov, Gerald J. Conlogue, Christina Warinner, Andrew T. Ozga, Krithivasan Sankaranarayanan, Anthony Griego, Daniel W. Deluca, Howard T. Eckels, Romuald K. Byczkiewicz, Tania Grgurich, Natalie A. Pelletier, Sarah A. Brownlee, Ana Marichal, Kylie Williamson, Yukiko Tonoike, Nicholas F. Bellantoni
"The Dead Shall Be Raised": Multidisciplinary Analysis Of Human Skeletons Reveals Complexity In 19th Century Immigrant Socioeconomic History And Identity In New Haven, Connecticut, Gary P. Aronsen, Lars Fehren-Schmitz, John Krigbaum, George D. Kamenov, Gerald J. Conlogue, Christina Warinner, Andrew T. Ozga, Krithivasan Sankaranarayanan, Anthony Griego, Daniel W. Deluca, Howard T. Eckels, Romuald K. Byczkiewicz, Tania Grgurich, Natalie A. Pelletier, Sarah A. Brownlee, Ana Marichal, Kylie Williamson, Yukiko Tonoike, Nicholas F. Bellantoni
Biology Faculty Articles
In July 2011, renovations to Yale-New Haven Hospital inadvertently exposed the cemetery of Christ Church, New Haven, Connecticut’s first Catholic cemetery. While this cemetery was active between 1833 and 1851, both the church and its cemetery disappeared from public records, making the discovery serendipitous. Four relatively well-preserved adult skeletons were recovered with few artifacts. All four individuals show indicators of manual labor, health and disease stressors, and dental health issues. Two show indicators of trauma, with the possibility of judicial hanging in one individual. Musculoskeletal markings are consistent with physical stress, and two individuals have arthritic indicators of repetitive movement/specialized …
Getting Back To Nature: Feralization In Animals And Plants, Eben Gering, Darren Incorvaia, R. Henriksen, Jeffrey Conner, Thomas Getty, Dominic Wright
Getting Back To Nature: Feralization In Animals And Plants, Eben Gering, Darren Incorvaia, R. Henriksen, Jeffrey Conner, Thomas Getty, Dominic Wright
Biology Faculty Articles
Formerly domesticated organisms and artificially selected genes often escape controlled cultivation, but their subsequent evolution is not well studied. In this review, we examine plant and animal feralization through an evolutionary lens, including how natural selection, artificial selection, and gene flow shape feral genomes, traits, and fitness. Available evidence shows that feralization is not a mere reversal of domestication. Instead, it is shaped by the varied and complex histories of feral populations, and by novel selection pressures. To stimulate further insight we outline several future directions. These include testing how ‘domestication genes’ act in wild settings, studying the brains and …
Crevalle Jack (Caranx Hippos), Alois Romanowski, David Kerstetter
Crevalle Jack (Caranx Hippos), Alois Romanowski, David Kerstetter
All Scans: Kerstetter Fisheries and Avian Ecology 3D Scan Series
Crevalle Jack (Caranx hippos) collected from Broward County, Florida and prepped by David Kerstetter in 2016.
Identification And Cloning Of Putative Serine Protease Inhibitor (Serpin) Genes In Rice (Oryza Sativa) And A Preliminary Approach To Generate Rnai Using The Cloned Sequences, Santanu De
Biology Faculty Articles
Programmed Cell Death (PCD) is an important mechanism of plant immune response against diseases. Serine protease inhibitors (‘serpins’) are a conserved superfamily of proteins that inhibit serine protease targets and prevent programmed cell death (PCD) in plants, in absence of pathogen infection. In this project, putative serpin genes in rice (Oryza sativa) which are homologous to necrotic/‘Nec’ serpin genes in Drosophila are identified by bioinformatic analyses. This is followed by cloning of specific exon sequences of the rice serpin genes identified. Finally, one of the cloned sequences is utilized in a series of steps to produce interfering RNA …
Hyperinsulinemia, Cancer And Maqui Berry: The Promise Of Nutritional Supplementation, Brett Deters, Mir Saleem
Hyperinsulinemia, Cancer And Maqui Berry: The Promise Of Nutritional Supplementation, Brett Deters, Mir Saleem
Biology Faculty Articles
Nutritional supplementation has long been studied as a possible treatment alternative or as an adjunct to the standard treatments for common ailments and diseases. According to the latest research, the Chilean maqui berry, Aristotelia chilensis, has been shown to reduce postprandial insulin levels by as much as fifty percent. The berry, which has been shown to be as effective as metformin at increasing insulin sensitivity and controlling blood glucose levels, follows a simple mechanism of action that involves the inhibition of sodium dependent glucose transporters in the small intestine, slowing the rate at which sugars enter the bloodstream and thereby …
Precision Nomenclature For The New Genomics, Harris A. Lewin, Jennifer A. Marshall Graves, Oliver A. Ryder, Alexander S. Graphodatsky, Stephen James O'Brien
Precision Nomenclature For The New Genomics, Harris A. Lewin, Jennifer A. Marshall Graves, Oliver A. Ryder, Alexander S. Graphodatsky, Stephen James O'Brien
Biology Faculty Articles
The confluence of two scientific disciplines may lead to nomenclature conflicts that require new terms while respecting historical definitions. This is the situation with the current state of cytology and genomics, which offer examples of distinct nomenclature and vocabularies that require reconciliation. In this article, we propose the new terms C-scaffold (for chromosome-scale assemblies of sequenced DNA fragments, commonly named scaffolds) and scaffotype (the resulting collection of C-scaffolds that represent an organism's genome). This nomenclature avoids conflict with the historical definitions of the terms chromosome (a microscopic body made of DNA and protein) and karyotype (the collection of images …
Avian Binocularity And Adaptation To Nocturnal Environments: Genomic Insights Froma Highly Derived Visual Phenotype, Rui Borges, Joao Fonseca, Cidalia Gomes, Warren E. Johnson, Stephen James O'Brien, Guojie Zhang, M. Thomas P. Gilbert, Erich D. Jarvis, Agostinho Antunes
Avian Binocularity And Adaptation To Nocturnal Environments: Genomic Insights Froma Highly Derived Visual Phenotype, Rui Borges, Joao Fonseca, Cidalia Gomes, Warren E. Johnson, Stephen James O'Brien, Guojie Zhang, M. Thomas P. Gilbert, Erich D. Jarvis, Agostinho Antunes
Biology Faculty Articles
Typical avian eyes are phenotypically engineered for photopic vision (daylight). In contrast, the highly derived eyes of the barn owl (Tyto alba) are adapted for scotopic vision (dim light). The dramatic modifications distinguishing barn owl eyes from other birds include: 1) shifts in frontal orientation to improve binocularity, 2) rod-dominated retina, and 3) enlarged corneas and lenses. Some of these features parallel mammalian eye patterns, which are hypothesized to have initially evolved in nocturnal environments. Here, we used an integrative approach combining phylogenomics and functional phenotypes of 211 eye-development genes across 48 avian genomes representing most avian orders, …
Inevitable Future: Space Colonization Beyond Earth With Microbes First, Jose Lopez, Raquel S. Peixoto, Alexandre S. Rosado
Inevitable Future: Space Colonization Beyond Earth With Microbes First, Jose Lopez, Raquel S. Peixoto, Alexandre S. Rosado
Biology Faculty Articles
Based on modern microbiology, we propose a major revision in current space exploration philosophy and planetary protection policy, especially regarding microorganisms in space. Mainly, microbial introduction should not be considered accidental but inevitable. We hypothesize the near impossibility of exploring new planets without carrying and/or delivering any microbial travelers. In addition, although we highlight the importance of controlling and tracking such contaminations—to explore the existence of extraterrestrial microorganisms—we also believe that we must discuss the role of microbes as primary colonists and assets, rather than serendipitous accidents, for future plans of extraterrestrial colonization. This paradigm shift stems partly from the …
The Vertebrate Tlr Supergene Family Evolved Dynamically By Gene Gain/Loss And Positive Selection Revealing A Host–Pathogen Arms Race In Birds, Imran Khan, Emanuel Maldonado, Liliana Silva, Daniela Almeida, Warren E. Johnson, Stephen James O'Brien, Guojie Zhang, Erich D. Jarvis, M. Thomas Gilbert, Agostinho Antunes
The Vertebrate Tlr Supergene Family Evolved Dynamically By Gene Gain/Loss And Positive Selection Revealing A Host–Pathogen Arms Race In Birds, Imran Khan, Emanuel Maldonado, Liliana Silva, Daniela Almeida, Warren E. Johnson, Stephen James O'Brien, Guojie Zhang, Erich D. Jarvis, M. Thomas Gilbert, Agostinho Antunes
Biology Faculty Articles
The vertebrate toll-like receptor (TLRs) supergene family is a first-line immune defense against viral and non-viral pathogens. Here, comparative evolutionary-genomics of 79 vertebrate species (8 mammals, 48 birds, 11 reptiles, 1 amphibian, and 11 fishes) revealed differential gain/loss of 26 TLRs, including 6 (TLR3, TLR7, TLR8, TLR14, TLR21, and TLR22) that originated early in vertebrate evolution before the diversification of Agnatha and Gnathostomata. Subsequent dynamic gene gain/loss led to lineage-specific diversification with TLR repertoires ranging from 8 subfamilies in birds to 20 in fishes. Lineage-specific loss of TLR8-9 and TLR13 in birds and gains of TLR6 and TLR10-12 in mammals …
Maladaptation In Feral And Domesticated Animals, Eben Gering, Darren Incorvaia, R. Henriksen, Dominic Wright
Maladaptation In Feral And Domesticated Animals, Eben Gering, Darren Incorvaia, R. Henriksen, Dominic Wright
Biology Faculty Articles
Selection regimes and population structures can be powerfully changed by domestication and feralization, and these changes can modulate animal fitness in both captive and natural environments. In this review, we synthesize recent studies of these two processes and consider their impacts on organismal and population fitness. Domestication and feralization offer multiple windows into the forms and mechanisms of maladaptation. Firstly, domestic and feral organisms that exhibit suboptimal traits or fitness allow us to identify their underlying causes within tractable research systems. This has facilitated significant progress in our general understandings of genotype–phenotype relationships, fitness trade‐offs, and the roles of population …
Global Spatial Risk Assessment Of Sharks Under The Footprint Of Fisheries, Nuno Queiroz, Nicolas E. Humphries, Ana Couto, Marisa Vedor, Ivo Da Costa, Ana M. M. Sequeira, Gonzalo Mucientes, Antonio M. Santos, Francisco J. Abascal, Debra L. Abercrombie, Katya Abrantes, David Acuna-Marrero, Andre S. Afonso, Darrell Anders, Gonzalo Araujo, Randall Arauz, Pascal Bach, Adam Barnett, Diego Bernal, Michael L. Berumen, Sandra Bessudo Lion, Natalia P. A. Bezerra, Antonin V. Blaison, Barbara A. Block, Mark E. Bond, Russell W. Bradford, Camrin D. Braun, Edward J. Brooks, Annabelle Brooks, Judith Brown, Barry D. Bruce, Michael Byrne, Steven E. Campana, Aaron B. Carlisle, Demian D. Chapman, Taylor K. Chapple, John Chisholm, Christopher R. Clarke, Erik G. Clua, Jesse E. M. Cochran, Estelle C. Crochelet, Laurent Dagorn, Ryan Daly, Daniel Devia Cortes, Thomas K. Doyle, Michael Drew, Clinton A. J. Duffy, Thor Erikson, Eduardo Espinoza, Luciana C. Ferreira, Francesco Ferretti, John D. Filmalter, G. Chris Fischer, Richard Fitzpatrick, Jorge Fontes, Fabian Forget, Mark Fowler, Malcolm P. Francis, Austin J. Gallagher, Enrico Gennari, Simon D. Goldsworthy, Matthew J. Gollock, Jonathan R. Green, Johan A. Gustafson, Tristan L. Guttridge, Hector M. Guzman, Neil Hammerschlag, Luke Harman, Fabio H.V. Hazin, Matthew Heard, Alex R. Hearn, John C. Holdsworth, Bonnie J. Holmes, Lucy A. Howey-Jordan, Mauricio Hoyos, Robert E. Hueter, Nigel E. Hussey, Charlie Huveneers, Dylan T. Irion, David M. P. Jacoby, Oliver J. D. Jewell, Ryan Johnson, Lance K. B. Jordan, Salvador J. Jorgensen, Warren Joyce, Clare A. Keating Daly, James T. Ketchum, A. Peter Klimley, Alison A. Kock, Pieter Koen, Felipe Ladino, Fernanda O. Lana, James S. E. Lea, Fiona Llewellyn, Warrick S. Lyon, Anna Macdonnell, Bruno C. L. Macena, Heather Marshall, Jaime D. Mcallister, Rory Mcauley, Michael A. Meyer, John J. Morris, Emily R. Nelson, Yannis P. Papastamatiou, Toby A. Patterson, Cesar Peñaherrera-Palma, Julian G. Pepperell, Simon J. Pierce, Francois Poisson, Lina Maria Quintero, Andrew J. Richardson, Paul J. Rogers, Christoph A. Rohner, David R. L. Rowat, Melita Samoilys, Jayson M. Semmens, Marcus Sheaves, George Shillinger, Mahmood S. Shivji, Sarika Singh, Gregory B. Skomal, Malcolm J. Smale, Laurenne B. Snyders, German Soler, Marc Soria, Kilian M. Stehfest, John D. Stevens, Simon R. Thorrold, Mariana T. Tolotti, Alison Towner, Paulo Travassos, John P. Tyminski, Frederic Vandeperre, Jeremy Vaudo, Yuuki Y. Watanabe, Sam B. Weber, Bradley M. Wetherbee, Timothy D. White, Sean Williams, Patricia M. Zarate, Robert Harcourt, Graeme C. Hays, Mark G. Meekan, Michele Thums, Xabier Irigoien, Victor M. Eguiluz, Carlos M. Duarte, Lara L. Sousa, Samantha J. Simpson, Emily J. Southall, David W. Sims
Global Spatial Risk Assessment Of Sharks Under The Footprint Of Fisheries, Nuno Queiroz, Nicolas E. Humphries, Ana Couto, Marisa Vedor, Ivo Da Costa, Ana M. M. Sequeira, Gonzalo Mucientes, Antonio M. Santos, Francisco J. Abascal, Debra L. Abercrombie, Katya Abrantes, David Acuna-Marrero, Andre S. Afonso, Darrell Anders, Gonzalo Araujo, Randall Arauz, Pascal Bach, Adam Barnett, Diego Bernal, Michael L. Berumen, Sandra Bessudo Lion, Natalia P. A. Bezerra, Antonin V. Blaison, Barbara A. Block, Mark E. Bond, Russell W. Bradford, Camrin D. Braun, Edward J. Brooks, Annabelle Brooks, Judith Brown, Barry D. Bruce, Michael Byrne, Steven E. Campana, Aaron B. Carlisle, Demian D. Chapman, Taylor K. Chapple, John Chisholm, Christopher R. Clarke, Erik G. Clua, Jesse E. M. Cochran, Estelle C. Crochelet, Laurent Dagorn, Ryan Daly, Daniel Devia Cortes, Thomas K. Doyle, Michael Drew, Clinton A. J. Duffy, Thor Erikson, Eduardo Espinoza, Luciana C. Ferreira, Francesco Ferretti, John D. Filmalter, G. Chris Fischer, Richard Fitzpatrick, Jorge Fontes, Fabian Forget, Mark Fowler, Malcolm P. Francis, Austin J. Gallagher, Enrico Gennari, Simon D. Goldsworthy, Matthew J. Gollock, Jonathan R. Green, Johan A. Gustafson, Tristan L. Guttridge, Hector M. Guzman, Neil Hammerschlag, Luke Harman, Fabio H.V. Hazin, Matthew Heard, Alex R. Hearn, John C. Holdsworth, Bonnie J. Holmes, Lucy A. Howey-Jordan, Mauricio Hoyos, Robert E. Hueter, Nigel E. Hussey, Charlie Huveneers, Dylan T. Irion, David M. P. Jacoby, Oliver J. D. Jewell, Ryan Johnson, Lance K. B. Jordan, Salvador J. Jorgensen, Warren Joyce, Clare A. Keating Daly, James T. Ketchum, A. Peter Klimley, Alison A. Kock, Pieter Koen, Felipe Ladino, Fernanda O. Lana, James S. E. Lea, Fiona Llewellyn, Warrick S. Lyon, Anna Macdonnell, Bruno C. L. Macena, Heather Marshall, Jaime D. Mcallister, Rory Mcauley, Michael A. Meyer, John J. Morris, Emily R. Nelson, Yannis P. Papastamatiou, Toby A. Patterson, Cesar Peñaherrera-Palma, Julian G. Pepperell, Simon J. Pierce, Francois Poisson, Lina Maria Quintero, Andrew J. Richardson, Paul J. Rogers, Christoph A. Rohner, David R. L. Rowat, Melita Samoilys, Jayson M. Semmens, Marcus Sheaves, George Shillinger, Mahmood S. Shivji, Sarika Singh, Gregory B. Skomal, Malcolm J. Smale, Laurenne B. Snyders, German Soler, Marc Soria, Kilian M. Stehfest, John D. Stevens, Simon R. Thorrold, Mariana T. Tolotti, Alison Towner, Paulo Travassos, John P. Tyminski, Frederic Vandeperre, Jeremy Vaudo, Yuuki Y. Watanabe, Sam B. Weber, Bradley M. Wetherbee, Timothy D. White, Sean Williams, Patricia M. Zarate, Robert Harcourt, Graeme C. Hays, Mark G. Meekan, Michele Thums, Xabier Irigoien, Victor M. Eguiluz, Carlos M. Duarte, Lara L. Sousa, Samantha J. Simpson, Emily J. Southall, David W. Sims
Biology Faculty Articles
Effective ocean management and conservation of highly migratory species depends on resolving overlap between animal movements and distributions and fishing effort. Yet, this information is lacking at a global scale. Here we show, using a big-data approach combining satellite-tracked movements of pelagic sharks and global fishing fleets, that 24% of the mean monthly space used by sharks falls under the footprint of pelagic longline fisheries. Space use hotspots of commercially valuable sharks and of internationally protected species had the highest overlap with longlines (up to 76% and 64%, respectively) and were also associated with significant increases in fishing effort. We …
Oomycete Metabarcoding Reveals The Presence Of Lagenidium Spp. In Phytotelmata, Paula Leoro-Garzon, Andrew J. Gonedes, Isabel Olivera, Aurelien Tartar
Oomycete Metabarcoding Reveals The Presence Of Lagenidium Spp. In Phytotelmata, Paula Leoro-Garzon, Andrew J. Gonedes, Isabel Olivera, Aurelien Tartar
Biology Faculty Articles
The oomycete genus Lagenidium, which includes the mosquito biocontrol agent L. giganteum, is composed of animal pathogens, yet is phylogenetically closely related to the well characterized plant pathogens Phytophthora and Pythium spp. These phylogenetic affinities were further supported by the identification of canonical oomycete effectors in the L. giganteum transcriptome, and suggested, mirroring the endophytic abilities demonstrated in entomopathogenic fungi, that L. giganteum may have similarly retained capacities to establish interactions with plant tissues. To test this hypothesis, culture-independent, metabarcoding analyses aimed at detecting L. giganteum in bromeliad phytotelmata (a proven mosquito breeding ground) microbiomes were performed. Two …
The Potential Of Socio-Biologically Relevant Mobile Applications To Attract Girls To Stem, Vanaja Nethi, Santanu De
The Potential Of Socio-Biologically Relevant Mobile Applications To Attract Girls To Stem, Vanaja Nethi, Santanu De
FDLA Journal
Stimulating girls’ interest in science, technology, engineering and mathematics (STEM) when they are in school, and sustaining that interest, is critical in motivating girls to choose STEM-related disciplines in higher education and enter STEM careers. Research indicates that girls show an interest in STEM until about 11-12 years of age, but this starts to wane by the time they are 15-16 years. Thus, there is a clear need to focus on sustaining the interest of girls in STEM at middle or high school levels. Research has shown that one of the main drivers that impact girls’ interest in STEM is …
Draft Genome Sequence Of Nitrosomonas Sp. Strain Apg5, A Betaproteobacterial Ammonia-Oxidizing Bacterium Isolated From Beach Sand, Hidetoshi Urakawa, Jorie L. Skutas, Jose Lopez
Draft Genome Sequence Of Nitrosomonas Sp. Strain Apg5, A Betaproteobacterial Ammonia-Oxidizing Bacterium Isolated From Beach Sand, Hidetoshi Urakawa, Jorie L. Skutas, Jose Lopez
Biology Faculty Articles
Nitrosomonas sp. strain APG5 (=NCIMB 14870 = ATCC TSA-116) was isolated from dry beach sand collected from a supralittoral zone of the northwest coast of the United States. The draft genome sequence revealed that it represents a new species of the cluster 6 Nitrosomonas spp. that is closely related to Nitrosomonas ureae and Nitrosomonas oligotropha.
Manipulating Neck Temperatures Alters Contagious Yawning In Humans, Valentina Ramirez, Colleen P. Ryan, Omar Tonsi Eldakar, Andrew C. Gallup
Manipulating Neck Temperatures Alters Contagious Yawning In Humans, Valentina Ramirez, Colleen P. Ryan, Omar Tonsi Eldakar, Andrew C. Gallup
Biology Faculty Articles
The existence of yawning across a diverse array of species has led many researchers to postulate its neurological significance. One hypothesis, which has garnered recent support, posits that yawns function to cool the brain by flushing hyperthermic blood away from the skull while simultaneously introducing a cooler arterial supply. The current study tested this hypothesis by examining how manipulations aimed at modifying carotid artery temperature, which in turn directly alters cranial temperature, influences contagious yawning in humans. Participants held either a warm (46 °C), cold (4 °C) or room temperature (22 °C) pack firmly to their neck, just over their …
Plasticity Of Mating Duration In Response To Slightly Biased Operational Sex Ratios In The Water Strider (Aquarius Remigis): The Effect Of Cohabitation Under Standard Laboratory Conditions, Andrew C. Gallup, Krista Pietruch, Omar Tonsi Eldakar
Plasticity Of Mating Duration In Response To Slightly Biased Operational Sex Ratios In The Water Strider (Aquarius Remigis): The Effect Of Cohabitation Under Standard Laboratory Conditions, Andrew C. Gallup, Krista Pietruch, Omar Tonsi Eldakar
Biology Faculty Articles
In polygynandrous species, males face the trade-off between the pursuit of increased mating opportunities and securing paternity. Within such systems, males need to accurately assess the social composition of the local environment to maximize fitness. Here, we investigated this capability in the water strider (Aquarius remigis), a semi-aquatic insect known to exhibit a broad spectrum of mating behaviors and inhabit a socially diverse and changing environment. Using a combination of methodological designs to track both within- and between-subject effects, individuals remained in same-sex housing prior to being exposed to slightly biased operational sex ratios (2:1 vs. 1:2) with or without …
White Shark Genome Reveals Ancient Elasmobranch Adaptations Associated With Wound Healing And The Maintenance Of Genome Stability, Nicholas J. Marra, Michael J. Stanhope, Nathaniel K. Jue, Minghui Wang, Qi Sun, Paulina D. Pavinski Bitar, Vincent P. Richards, Aleksey S. Komissarov, Mike Rayko, Sergey Kliver, Bryce J. Stanhope, Chuck Winkler, Stephen James O'Brien, Agostinho Antunes, Salvador Jorgensen, Mahmood S. Shivji
White Shark Genome Reveals Ancient Elasmobranch Adaptations Associated With Wound Healing And The Maintenance Of Genome Stability, Nicholas J. Marra, Michael J. Stanhope, Nathaniel K. Jue, Minghui Wang, Qi Sun, Paulina D. Pavinski Bitar, Vincent P. Richards, Aleksey S. Komissarov, Mike Rayko, Sergey Kliver, Bryce J. Stanhope, Chuck Winkler, Stephen James O'Brien, Agostinho Antunes, Salvador Jorgensen, Mahmood S. Shivji
Biology Faculty Articles
The white shark (Carcharodon carcharias; Chondrichthyes, Elasmobranchii) is one of the most publicly recognized marine animals. Here we report the genome sequence of the white shark and comparative evolutionary genomic analyses to the chondrichthyans, whale shark (Elasmobranchii) and elephant shark (Holocephali), as well as various vertebrates. The 4.63-Gbp white shark genome contains 24,520 predicted genes, and has a repeat content of 58.5%. We provide evidence for a history of positive selection and gene-content enrichments regarding important genome stability-related genes and functional categories, particularly so for the two elasmobranchs. We hypothesize that the molecular adaptive emphasis on genome stability …
The Efficacy Of Whole Human Genome Capture On Ancient Dental Calculus And Dentin, Kirsten A. Ziesemer, Jazmin Ramos-Madrigal, Allison E. Mann, Bernd W. Brandt, Krithivasan Sankaranarayanan, Andrew T. Ozga, Menno Hoogland, Courtney A. Hofman, Domingo C. Salazar-Garcia, Bruno Frohlich, George R. Miller, Anne C. Stone, Mark Aldenderfer, Cecil M. Lewis Jr., Corinne L. Hofman, Christina Warinner, Hannes Schroeder
The Efficacy Of Whole Human Genome Capture On Ancient Dental Calculus And Dentin, Kirsten A. Ziesemer, Jazmin Ramos-Madrigal, Allison E. Mann, Bernd W. Brandt, Krithivasan Sankaranarayanan, Andrew T. Ozga, Menno Hoogland, Courtney A. Hofman, Domingo C. Salazar-Garcia, Bruno Frohlich, George R. Miller, Anne C. Stone, Mark Aldenderfer, Cecil M. Lewis Jr., Corinne L. Hofman, Christina Warinner, Hannes Schroeder
Biology Faculty Articles
Objectives
Dental calculus is among the richest known sources of ancient DNA in the archaeological record. Although most DNA within calculus is microbial, it has been shown to contain sufficient human DNA for the targeted retrieval of whole mitochondrial genomes. Here, we explore whether calculus is also a viable substrate for whole human genome recovery using targeted enrichment techniques.
Materials and methods
Total DNA extracted from 24 paired archaeological human dentin and calculus samples was subjected to whole human genome enrichment using in‐solution hybridization capture and high‐throughput sequencing.
Results
Total DNA from calculus exceeded that of dentin in all cases, …
Depth-Dependent Environmental Drivers Of Microbial Plankton Community Structure In The Northern Gulf Of Mexico, Cole Easson, Jose Lopez
Depth-Dependent Environmental Drivers Of Microbial Plankton Community Structure In The Northern Gulf Of Mexico, Cole Easson, Jose Lopez
Biology Faculty Articles
The Gulf of Mexico (GoM) is a dynamic marine ecosystem influenced by multiple natural and anthropogenic processes and inputs, such as the intrusion of warm oligotrophic water via the Loop Current, freshwater and nutrient input by the Mississippi River, and hydrocarbon inputs via natural seeps and industrial spills. Microbial plankton communities are important to pelagic food webs including in the GoM but understanding the drivers of the natural dynamics of these passively distributed microorganisms can be challenging in such a large and heterogeneous system. As part of the DEEPEND consortium, we applied high throughput 16S rRNA sequencing to investigate the …
Pvsripo Effect On Cancer, Vishal Jindal, Matthew Lee, Darshan Rola, Mir Saleem
Pvsripo Effect On Cancer, Vishal Jindal, Matthew Lee, Darshan Rola, Mir Saleem
Biology Faculty Articles
PVSRIPO, a variant of the poliovirus, is a revolutionary virus that demonstrates key characteristics for oncolytic virotherapy due to its ability to attack glioblastomas. The first criteria that PVSRIPO demonstrates is tumor-targeting tropism. PVSRIPO binds to nectin-like molecule 5 (Necl-5), a poliovirus receptor (PVR), found on different types of cancers such as lung cancer, colorectal cancer, and glioblastomas. This allows the virus to have a high binding affinity to tumor cells. Secondly, after modifying the poliovirus by substituting its internal ribosome entry site (IRES) with the Human Rhinovirus 2's (HRV2) IRES, the poliovirus becomes PVSRIPO, an attenuated version of the …
A Physical And Genetic Map Of Cannabis Sativa Identifies Extensive Rearrangements At The Thc/Cbd Acid Synthase Loci, Kaitlin Laverty, Jake Stout, Mitchell Sullivan, Hardik Shah, Navdeep Gill, Larry Holbrook, Gintaras Deikus, Robert Sebra, Timothy Hughes, Jonathan Page, Harm Van Bakel
A Physical And Genetic Map Of Cannabis Sativa Identifies Extensive Rearrangements At The Thc/Cbd Acid Synthase Loci, Kaitlin Laverty, Jake Stout, Mitchell Sullivan, Hardik Shah, Navdeep Gill, Larry Holbrook, Gintaras Deikus, Robert Sebra, Timothy Hughes, Jonathan Page, Harm Van Bakel
Biology Faculty Articles
Cannabis sativa is widely cultivated for medicinal, food, industrial, and recreational use, but much remains unknown regarding its genetics, including the molecular determinants of cannabinoid content. Here, we describe a combined physical and genetic map derived from a cross between the drug-type strain Purple Kush and the hemp variety “Finola.” The map reveals that cannabinoid biosynthesis genes are generally unlinked but that aromatic prenyltransferase (AP), which produces the substrate for THCA and CBDA synthases (THCAS and CBDAS), is tightly linked to a known marker for total cannabinoid content. We further identify the gene encoding CBCA synthase (CBCAS …
Medical University Of Graz - Summer Internship 2018, Nada Belal
Medical University Of Graz - Summer Internship 2018, Nada Belal
Trick to the Treat of Internships and Research
Program Overview:
- Assist a transplant team at Medical University of Graz for 6 weeks
- Mainly general surgery and transplantation procedures, but can observe and assist in other types of operations, as well.
- Great opportunity to apply all that you have learned in the classroom through hands-on experience.
The University Of Texas Md Anderson Cancer Center - Biology Summer Internship, Marla Fortoul
The University Of Texas Md Anderson Cancer Center - Biology Summer Internship, Marla Fortoul
Trick to the Treat of Internships and Research
Program Overview:
- 10 week program
- MD Anderson Cancer Center in Houston, Texas
- Students will be matched with a faculty mentor in any number of areas of biomedical research where a project will be assigned.
- Participants work alongside the mentor in a lab or clinic on projects designed by faculty to reflect current research.
- Workshops and lectures provide opportunities to connect with faculty, residents, postdoctoral and clinical fellows, and other participants.
- Through the program, students assess goals related to careers in oncology research and patient care.
- Symposium in which participants present talks and posters on their research projects to peers and …
Osteogenesis Of Dental Stem Cells, Jerry Ennolikara
Osteogenesis Of Dental Stem Cells, Jerry Ennolikara
Trick to the Treat of Internships and Research
Program Overview:
- This research lab is dedicated to the study of bioengineering bone tissue, an application of biology research within medicine known as "regenerative medicine," through a variety of in-vivo and in-vitro projects.
- The primary focus of our lab is to replace a lifetime of bone graft surgeries associated with cleft palate, a congenital disorder where the palatal process of the maxilla fails to fuse during development, with a noninvasive injectable treatment.
- The lab upholds the central motif of tissue engineering of "cells, scaffolds, and growth factors" with our research utilizing periodontal ligamental stem cells/human gingival mesenchymal stem cells; 3D …
Ussouthcom's Office Of The Command Surgeon - Pathway Internship Experience, Alexander Jakub Martinek
Ussouthcom's Office Of The Command Surgeon - Pathway Internship Experience, Alexander Jakub Martinek
Trick to the Treat of Internships and Research
Program Overview: The Office of the Command Surgeon enables and synchronizes health engagement activities utilizing the whole of government approach to enhance regional health preparedness and increase our partner nations’ military and security forces’ medical capabilities.
Practicum In Biology I: Gastroenterology Site, Roksana Hesari
Practicum In Biology I: Gastroenterology Site, Roksana Hesari
Trick to the Treat of Internships and Research
Program Overview:
- Instructor - Dr. Mark Jaffe, DPM
- Didactic and experiential learning in applied settings
- Primary research literature exposure in field of interest
- Weekly face-to-face lectures for three hours
- Practicum site shifts for minimum 5 hours weekly
- Partnerships with Alvin Sherman Library and Career Services Department
Cleveland Clinic Florida - Summer Scholar Program, Marina Handal
Cleveland Clinic Florida - Summer Scholar Program, Marina Handal
Trick to the Treat of Internships and Research
Program Overview:
- Cleveland Clinic Florida’s Summer Scholar Program is designed to allow students to gain shadowing experience in the medical field via the clinical and hospital settings.
- Students are assigned 3 rotations total within the 6-week span of the program; high school assignments run for a total of 3 weeks.
- Rotations include Internal Medicine, Cardiology, Neurosurgery, ICC, Emergency Medicine, and various other subspecialties.
- Students can expect to be at the Weston hospital Monday-Friday 8 am- 5 pm (varies based on rotation/clinic hours/surgery schedule).
- Attend weekly lectures that consist of discussion of the ethics of medicine, educational path to becoming a …
Cleveland Clinic Summer Scholars Program, Vanessa Cruise
Cleveland Clinic Summer Scholars Program, Vanessa Cruise
Trick to the Treat of Internships and Research
Program Overview:
- Currently available to: High school juniors going into senior year and pre-med college freshmen that have completed their first year of college
- College freshman program is a 6 week program (3 rotations, 2 weeks long each). Rotations can be aligned with your preferred specialties if resources allow.