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Articles 61 - 90 of 370
Full-Text Articles in Biology
Lake Salinization Drives Consistent Losses Of Zooplankton Abundance And Diversity Across Coordinated Mesocosm Experiments, Matthew Schuler
Lake Salinization Drives Consistent Losses Of Zooplankton Abundance And Diversity Across Coordinated Mesocosm Experiments, Matthew Schuler
Department of Biology Faculty Scholarship and Creative Works
Human-induced salinization increasingly threatens inland waters; yet we know little about the multifaceted response of lake communities to salt contamination. By conducting a coordinated mesocosm experiment of lake salinization across 16 sites in North America and Europe, we quantified the response of zooplankton abundance and (taxonomic and functional) community structure to a broad gradient of environmentally relevant chloride concentrations, ranging from 4 to ca. 1400 mg Cl− L−1. We found that crustaceans were distinctly more sensitive to elevated chloride than rotifers; yet, rotifers did not show compensatory abundance increases in response to crustacean declines. For crustaceans, our …
Widespread Variation In Salt Tolerance Within Freshwater Zooplankton Species Reduces The Predictability Of Community-Level Salt Tolerance, Matthew Schuler
Widespread Variation In Salt Tolerance Within Freshwater Zooplankton Species Reduces The Predictability Of Community-Level Salt Tolerance, Matthew Schuler
Department of Biology Faculty Scholarship and Creative Works
The salinization of freshwaters is a global threat to aquatic biodiversity. We quantified variation in chloride (Cl−) tolerance of 19 freshwater zooplankton species in four countries to answer three questions: (1) How much variation in Cl− tolerance is present among populations? (2) What factors predict intraspecific variation in Cl− tolerance? (3) Must we account for intraspecific variation to accurately predict community Cl− tolerance? We conducted field mesocosm experiments at 16 sites and compiled acute LC50s from published laboratory studies. We found high variation in LC50s for Cl− tolerance in multiple species, which, in the …
A Bioinformatics Approach For Evaluating Evolutionary Convergence Of Gene Family Size In Hematophagous Insects, Mbemba Ceesay
A Bioinformatics Approach For Evaluating Evolutionary Convergence Of Gene Family Size In Hematophagous Insects, Mbemba Ceesay
Theses, Dissertations and Culminating Projects
The act of blood-feeding can be nutritionally rewarding for blood-feeding arthropods. However, blood digestion can release pro-oxidant molecules such as heme and iron at potentially harmful levels. If left uncontrolled, this heme/iron can cause oxidative damage and eventually cell death. This has led to the evolution of various adaptations that protect blood-feeding arthropods against iron- and heme-associated damage. Here I postulate that the signature of this adaptation can be observed in patterns of gene family size. To test this hypothesis, I explore convergent evolutionary expansions and contractions of gene families in distinct lineages of hematophagous insects. Specifically, I compare the …
Optimizing Crispr/Cas9 Transfection Protocol To Generate A Tet-On Inducible Sk-Mel 24 Cell Lines To Better Study Icer, Abdulkader Hallak
Optimizing Crispr/Cas9 Transfection Protocol To Generate A Tet-On Inducible Sk-Mel 24 Cell Lines To Better Study Icer, Abdulkader Hallak
Theses, Dissertations and Culminating Projects
Inducible cAMP Early Repressor (ICER) is a dominant transcription repressor of the cAMP Responsive Element Modulator (CREM) and cAMP Responsive Element Protein (CREB) family of transcription factors. ICER isoforms are differently expressed in various cell types and are involved in essential functions including hormonal regulation, circadian rhythm, spermatogenesis, and immune response. In the context of cancer, ICER is proposed as a tumor suppressor in leukemia, prostate, pituitary cancers, and melanoma. In melanoma, ICER is targeted for degradation during tumorigenesis and highly upregulated during regression, further highlighting its potency as a tumor suppressor. Inside the nucleus, ICER targets oncogenes and key …
Secondary Analysis Of Chip-Seq Dataset And Genomic Interactions Of Icer, Karem Rivera
Secondary Analysis Of Chip-Seq Dataset And Genomic Interactions Of Icer, Karem Rivera
Theses, Dissertations and Culminating Projects
The Inducible cyclic AMP (cAMP) Early Repressor (ICER) is an endogenous transcriptional repressor of the cAMP-mediated signaling gene transcription pathway and belongs to the CRE-binding protein (CREB)/CRE modulator (CREM) gene family. ICER is associated to many functions and biological processes in the immune system, brain, regulation of spermatogenesis, circadian control of transcription, apoptosis and metabolic functions, and of particular interest, has been shown to act like a tumor suppressor. Recent findings from our laboratory suggest that ICER might have a role in DNA repair, but further experiments need to be performed. In this research, we aimed to elucidate the function …
Persistence And Expansion Of Cryptic Endangered Red Wolf Genomic Ancestry Along The American Gulf Coast, Bridgett M. Vonholdt, Kristin E. Brzeski, Matthew L. Aardema, Christopher J. Schell, Linda Y. Rutledge, Steven R. Fain, Amy C. Shutt, Anna Linderholm, William J. Murphy
Persistence And Expansion Of Cryptic Endangered Red Wolf Genomic Ancestry Along The American Gulf Coast, Bridgett M. Vonholdt, Kristin E. Brzeski, Matthew L. Aardema, Christopher J. Schell, Linda Y. Rutledge, Steven R. Fain, Amy C. Shutt, Anna Linderholm, William J. Murphy
Department of Biology Faculty Scholarship and Creative Works
Admixture and introgression play a critical role in adaptation and genetic rescue that has only recently gained a deeper appreciation. Here, we explored the geographical and genomic landscape of cryptic ancestry of the endangered red wolf that persists within the genome of a ubiquitous sister taxon, the coyote, all while the red wolf has been extinct in the wild since the early 1980s. We assessed admixture across 120,621 single nucleotiode polymorphism (SNP) loci genotyped in 293 canid genomes. We found support for increased red wolf ancestry along a west-to-east gradient across the southern United States associated with historical admixture in …
Examination Of Changes In Gene Family Size In Carnivorous Plants Through Genomic Analysis, Moonia Ammari
Examination Of Changes In Gene Family Size In Carnivorous Plants Through Genomic Analysis, Moonia Ammari
Theses, Dissertations and Culminating Projects
The traits associated with carnivory in plants have independently evolved within several orders of Angiosperm. Despite this lack of a common origin, carnivorous plants show many remarkably similar adaptations, suggesting that common evolutionary pressures may have shaped these species. Here, we hypothesize that one common trait carnivorous plants share is the number of genes associated with specific biological functions, such as nutrient transport. To test this hypothesis, we first identified genes and gene families in the model plant species Arabidopsis thaliana that are associated with previously characterized biological functions that may be important for plant carnivory. We then compared the …
The Susceptibility For Recreational Boating To Serve As A Vector For Harmful Algal Blooms, John Michael Thraen
The Susceptibility For Recreational Boating To Serve As A Vector For Harmful Algal Blooms, John Michael Thraen
Theses, Dissertations and Culminating Projects
To combat the spread of invasive and nuisance aquatic species, recreational boating has many recommendations and regulations in place for boaters to properly treat their boats in between uses in separate locations. While protection procedures are in place for preventing the spread of invasive mussel and plant species, there is no sufficient procedure in regard to the spread of cyanobacterial species. The objective of this study was to investigate whether common drying procedures employed in these treatment practices were capable of additionally preventing the spread of cyanobacterial species so as they may help prevent the spread of algal blooms throughout …
Parasite Variability In The Invasive Crayfish, Faxonius Rusticus, In Northern New Jersey, Nathan Martin Klunk
Parasite Variability In The Invasive Crayfish, Faxonius Rusticus, In Northern New Jersey, Nathan Martin Klunk
Theses, Dissertations and Culminating Projects
The Northeast United States has been thoroughly invaded by the well-known invasive crayfish species Faxonius rusticus (rusty crayfish). Similar to the exploration of man to new regions, the spread of invasive species can cause the introduction of new diseases and parasites while conversely the invader has to deal with the already existing diseases and parasites. For crayfish, the most notable of these is a fungal plague, which has a poorly understood distribution in the United States. In this study, I collected rusty crayfish in Northern New Jersey to better understand the locations where they exist in the state. I also …
Demographic Expansions And The Emergence Of Host Specialization In Genetically Distinct Ecotypes Of The Tick-Transmitted Bacterium Anaplasma Phagocytophilum, Matthew L. Aardema, Nina V. Bates, Qiana E. Archer, Friederike D.Von Loewenich
Demographic Expansions And The Emergence Of Host Specialization In Genetically Distinct Ecotypes Of The Tick-Transmitted Bacterium Anaplasma Phagocytophilum, Matthew L. Aardema, Nina V. Bates, Qiana E. Archer, Friederike D.Von Loewenich
Department of Biology Faculty Scholarship and Creative Works
In Europe, genetically distinct ecotypes of the tick-vectored bacterium Anaplasma phagocytophilum circulate among mammals in three discrete enzootic cycles. To date, potential ecological factors that contributed to the emergence of these divergent ecotypes have been poorly studied. Here, we show that the ecotype that predominantly infects roe deer (Capreolus capreolus) is evolutionarily derived. Its divergence from a host generalist ancestor occurred after the last glacial maximum as mammal populations, including roe deer, recolonized the European mainland from southern refugia. We also provide evidence that this host specialist ecotype's effective population size (Ne) has tracked changes in the population of its …
Evaluation Of Kappa Opioid Receptor Specific Compounds And Their Effect On Ptsd-Like Behavioral Activity, Daniel Murnock
Evaluation Of Kappa Opioid Receptor Specific Compounds And Their Effect On Ptsd-Like Behavioral Activity, Daniel Murnock
Theses, Dissertations and Culminating Projects
Background: Post-traumatic stress disorder (PTSD) is a complex and multifaceted neurological disorder that is characterized by intrusive thoughts, avoidance behaviors, alterations in cognition and mood, and alterations in arousal and reactivity. Current studies utilize stress paradigms to mimic behavioral symptoms and neurobiological changes associated with PTSD. The project aims to instead utilize the kappa opioid system and three distinct Kappa Opioid Receptorspecific compounds (Salvinorin A, U50,488, and nor-BNI) to induce these changes. Pharmacokinetic analysis of Salvinorin A and U50,488 revealed a time of peak plasma concentration (Tmax) of 0.25 hours in both groups. 3-Chamber Social Novelty testing revealed a significant …
Feeding Preference Of The Sea Urchin Arbacia Punctulata For Algal Turf Over Kelp In A Degraded Kelp Forest Ecosystem, Kenneth J. Hamel
Feeding Preference Of The Sea Urchin Arbacia Punctulata For Algal Turf Over Kelp In A Degraded Kelp Forest Ecosystem, Kenneth J. Hamel
Theses, Dissertations and Culminating Projects
Increasingly severe ocean warming and marine heatwave events are driving declines in habitat-forming kelps worldwide. Direct mortality from extreme temperatures, coupled with destabilization of kelp forest communities, commonly trigger ecological community shifts from dominant kelp forests to an algal turf dominated state. Opportunistic algal turf species are more resilient to warming and lack the fundamental structure of kelp forests, and thus reduce ecosystem services and biodiversity. Once in place, algal turf communities contain ecological feedback mechanisms, diminishing kelp recruitment, and potential recovery. The various feedback mechanisms and ecological thresholds that maintain or drive community shifts between kelp forest and algal …
Targeting Prosthetic Joint Infections Using Modified Egcg Derivatives With Antibiotics, Kavneet Chahil
Targeting Prosthetic Joint Infections Using Modified Egcg Derivatives With Antibiotics, Kavneet Chahil
Theses, Dissertations and Culminating Projects
Prosthetic joint implantations have revolutionized orthopedic medicine by allowing individuals to regain physical function with minimal side effects. However, they are susceptible to post- surgical complications due to bacterial infections. Three significant bacteria that are responsible for the development of joint infections include Staphylococcus epidermidis, Staphylococcus aureus, and Pseudomonas aeruginosa, which act by adhering to the prosthesis and form biofilms thus becoming antibiotic-resistant. It has been reported that green tea polyphenols, which are extracted from the leaves of the Camellia sinensis plant, have antibacterial, antioxidant, and anti- inflammatory properties. The purified, and modified epigallocatechin-3-gallate-stearate (EGCGS) and palmitoyl-epigallocatechin-3-gallate (P-EGCG) are more …
Assessment Of The Asexual Reproductive Strategies Of The Invasive Clinging Jellyfish Gonionemus Vertens, Valin Jarred Booker
Assessment Of The Asexual Reproductive Strategies Of The Invasive Clinging Jellyfish Gonionemus Vertens, Valin Jarred Booker
Theses, Dissertations and Culminating Projects
Anthropogenic activities are dispersing organisms at higher rates and this dispersal leads to organisms having a higher chance at becoming invasive. The Clinging Jellyfish, Gonionemus vertens, was originally from the north Pacific Ocean, but was identified in New Jersey’s coastal waters in 2016. G. vertens undergo a complex life history with an asexual polyp stage and the sexual medusa stage. Little is known about their polyp stage, which shows multiple asexual reproductive strategies that can generate high densities of medusa. Asexual reproduction of polyps was observed in 2020 to assess the rate of clonal production. Cultured polyps can have several …
Cas9 Grna And Homologous Recombinant Plasmid Integrate Inducible Ha-N-Icer In The Aavs1 Locus Of Sk-Mel-24 Cells, Douglas Job
Cas9 Grna And Homologous Recombinant Plasmid Integrate Inducible Ha-N-Icer In The Aavs1 Locus Of Sk-Mel-24 Cells, Douglas Job
Theses, Dissertations and Culminating Projects
Melanoma is one of the most aggressive forms of cancer and is prone to metastasis. Once melanoma metastasizes, it is difficult to treat as patients often become immune to MAPK inhibitors and other therapeutic agents. Small molecules, such as immune checkpoint inhibitors, have demonstrated success as an adjunct to melanoma treatment. As a small, 18kDa molecule with tumor suppressing properties, research using ICER continues to provide positive anti-tumor effects. ICER regulates cAMP-induced transcription as a powerful, dominant-negative transcriptional repressor. Recent research demonstrated that the fusion tag hemagglutinin (HA), when fused to ICER’s N-terminus, increased ICER’s half-life and apoptotic activity in …
Turning Tadpoles: Effects Of Salinity And Lateralization On Hyla Versicolor Escape Behaviors, Victor Lopiccolo
Turning Tadpoles: Effects Of Salinity And Lateralization On Hyla Versicolor Escape Behaviors, Victor Lopiccolo
Theses, Dissertations and Culminating Projects
Road salt, which is used as a roadway deicer in the winter time, is a major contributor to the salinization of freshwater habitats. Amphibians are particularly vulnerable to the salinization of aquatic environments due to the reliance of many species on pond, lake, and stream habitat in their aquatic larval stage. This study examined how Northern Gray Treefrog (Hyla versicolor) tadpole behavior is affected by salinity in a multiple t-maze. Alternate turning is sequential turning in opposite directions. Alternating turns lead the animal further from the starting point, and are innate behaviors associated with foraging, exploration, and escape. A multiple …
Spatial Distribution And Recruitment Of The Botrylloides Violaceus And Botryllus Schlosseri Tunicates In Barnegat Bay, New Jersey, Kaitlyn Maguire
Spatial Distribution And Recruitment Of The Botrylloides Violaceus And Botryllus Schlosseri Tunicates In Barnegat Bay, New Jersey, Kaitlyn Maguire
Theses, Dissertations and Culminating Projects
Botrylloides violaceus and Botryllus schlosseri, colonial ascidians, are known invasive species of the North American Atlantic coast. The tunicates take residence and grow on native eelgrass (Zostera marina) blades, potentially negatively affecting eelgrass growth rate by means of smothering which reduces the plants ability to photosynthesize. Zostera marina is an important habitat, food source, and an indicator of environmental health. Invasive tunicates can decrease the amount of light that eelgrass receives which in turn, decreases the rate of growth of eelgrass. In the summer months of 2021, the relationship and abundance between the invasive tunicates B. schlosseri and B. violaceus …
Green Tea Polyphenols Egcg-S And P-Egcg Containing Formulations Effectively Inhibit Growth And Biofilm Formation Of Eskape Bacteria, Calvin William Taylor
Green Tea Polyphenols Egcg-S And P-Egcg Containing Formulations Effectively Inhibit Growth And Biofilm Formation Of Eskape Bacteria, Calvin William Taylor
Theses, Dissertations and Culminating Projects
The field of medical microbiology has prospered for decades, finding treatments and cures for a multitude of bacterial infections. While success has been found in certain areas, challenges have arisen along the way. One of those challenges being the group of bacteria known as ESKAPE. The ESKAPE bacteria (Enterococcus faecium, Staphylococcus aureus, Klebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa, and Enterobacter species) have developed their multidrug resistance through adaptation to excessive drug use or prescription, unnecessary antimicrobial utilization, and substandard pharmaceuticals. They are the major cause of nosocomial infections throughout the world. With the ever-growing concern of antibiotic resistance in treating …
Evaluation Of Ranavirus Major Capsid Protein Gene Sequence Mutations In United States East Coast Frog And Tadpole Populations, Erin Marie Tyll
Evaluation Of Ranavirus Major Capsid Protein Gene Sequence Mutations In United States East Coast Frog And Tadpole Populations, Erin Marie Tyll
Theses, Dissertations and Culminating Projects
Infectious disease is a leading cause of death in ectothermic taxa including amphibians, reptiles, and bony fish. Frog Virus 3 (FV3) Ranavirus is a prominent pathogen that infects frog and tadpole populations with lethal consequences, especially for pre-metamorphosed individuals. Wood frogs (Lithobates sylvaticus) are particularly susceptible to FV3 infection and mortality events. Conservation of this animal is a critical effort for the maintenance of these ecologically significant animals. Amphibians contribute to the regulation of insect pest levels, energy transfer between aquatic and terrestrial habitats, algae community productivity and function, and vertebrate biomass. Understanding genetic variations of FV3 is crucial to …
Isolation And Analysis Of Single-Stranded Dna Aptamers For The Detection Of Ranavirus, Stephanie Zapata
Isolation And Analysis Of Single-Stranded Dna Aptamers For The Detection Of Ranavirus, Stephanie Zapata
Theses, Dissertations and Culminating Projects
The current molecular diagnostic methods for detection of deadly pathogens within a population can be time consuming and expensive. When surveying a population for the presence of a disease, time is a valuable resource. Therefore, a rapid pathogen test to use in the field will allow for faster detection of disease that can lead to determining a course of action for conservation of a species. Ranavirus is a double-stranded DNA virus that can cause mass mortality events in amphibian, reptile and fish populations. The disease can have the potential to wipe out entire populations or species if not controlled, having …
Evidence That The Transcriptional Repressor Icer Is Regulated Via The N-End Rule For Ubiquitination, Angelo Cirinelli, Justin Wheelan, Christopher Grieg, Carlos A. Molina
Evidence That The Transcriptional Repressor Icer Is Regulated Via The N-End Rule For Ubiquitination, Angelo Cirinelli, Justin Wheelan, Christopher Grieg, Carlos A. Molina
Department of Biology Faculty Scholarship and Creative Works
ICER is a transcriptional repressor that is mono- or poly-ubiquitinated. This either causes ICER to be translocated from the nucleus, or degraded via the proteasome, respectively. In order to further studies the proteins involved in ICER regulation mass spectrometry analysis was performed to identify potential candidates. We identified twenty eight ICER-interacting proteins in human melanoma cells, Sk-Mel-24. In this study we focus on two proteins with potential roles in ICER proteasomal degradation in response to the N-end rule for ubiquitination: the N-alpha-acetyltransferase 15 (NAA15) and the E3 ubiquitin-protein ligase UBR4. Using an HA-tag on the N- or C-terminus of ICER …
Seasonal Trends In Adult Apparent Survival And Reproductive Trade-Offs Reveal Potential Constraints To Earlier Nesting In A Migratory Bird, Kathleen R. Callery, John A. Smallwood, Anjolene R. Hunt, Emilie R. Snyder, Julie A. Heath
Seasonal Trends In Adult Apparent Survival And Reproductive Trade-Offs Reveal Potential Constraints To Earlier Nesting In A Migratory Bird, Kathleen R. Callery, John A. Smallwood, Anjolene R. Hunt, Emilie R. Snyder, Julie A. Heath
Department of Biology Faculty Scholarship and Creative Works
Birds aim to optimize resources for feeding young and self-maintenance by timing reproduction to coincide with peak food availability. When reproduction is mistimed, birds could incur costs that affect their survival. We studied whether nesting phenology correlated with the apparent survival of American kestrels (Falco sparverius) from two distinct populations and examined trends in clutch-initiation dates. We estimated apparent survival using multi-state mark-recapture models with nesting timing, nesting success, sex, age, and weather covariates. Nesting timing predicted the apparent survival of successful adults; however, the effect differed between populations. Early nesting kestrels had higher apparent survival than later nesters in …
Effect Of Soil Conditions On Invasive Purple Loosestrife Compared To Native Species, Madeline Ruth Baum
Effect Of Soil Conditions On Invasive Purple Loosestrife Compared To Native Species, Madeline Ruth Baum
Theses, Dissertations and Culminating Projects
Purple loosestrife (Lythrum salicaria) is an invasive plant that has degraded many wetland habitats since its initial introduction to the United States in the early 19th century. To aid in managing purple loosestrife, it is important to study how purple loosestrife grows under variable environmental conditions compared to common native species, which can help managers understand which habitats are most at-risk of invasion. High or low salinity and pH are often barriers to plant growth, and the stress caused by these environmental conditions can cause plants to deplete their starch reserves. If native species are more negatively affected by stressful …
Grazing Influences Biomass Production And Protein Content Of Alpine Meadows, Laia Jarque-Bascuñana, Juan Antonio Calleja, Miguel Ibañez, Jordi Bartolomé, Elena Albanell, Johan Espunyes, Arturo Gálvez-Cerón, Josep María López-Martín, Miriam Villamuelas, Diana Gassó, Xavier Fernández-Aguilar, Andreu Colom-Cadena, Jennifer Adams Krumins, Emmanuel Serrano
Grazing Influences Biomass Production And Protein Content Of Alpine Meadows, Laia Jarque-Bascuñana, Juan Antonio Calleja, Miguel Ibañez, Jordi Bartolomé, Elena Albanell, Johan Espunyes, Arturo Gálvez-Cerón, Josep María López-Martín, Miriam Villamuelas, Diana Gassó, Xavier Fernández-Aguilar, Andreu Colom-Cadena, Jennifer Adams Krumins, Emmanuel Serrano
Department of Biology Faculty Scholarship and Creative Works
Alpine grasslands are essential for carbon sequestration and food supply for domestic and wild herbivores inhabiting mountainous areas worldwide. These biomes, however, are alternatively threatened by the abandonment of agricultural and livestock practices leading to a fast-growing shrubification process while other mountain grasslands are suffering from the impacts of overgrazing. The functioning of alpine meadow ecosystems is primarily driven by climatic conditions, land-use legacies and grazing. However, although it is critically important, the role of large herbivores on the aboveground biomass and protein content of palatable plants is poorly understood for most alpine meadows. In this work, we explore the …
Current Water Quality Guidelines Across North America And Europe Do Not Protect Lakes From Salinization, Matthew Schuler
Current Water Quality Guidelines Across North America And Europe Do Not Protect Lakes From Salinization, Matthew Schuler
Department of Biology Faculty Scholarship and Creative Works
Human-induced salinization caused by the use of road deicing salts, agricultural practices, mining operations, and climate change is a major threat to the biodiversity and functioning of freshwater ecosystems. Yet, it is unclear if freshwater ecosystems are protected from salinization by current water quality guidelines. Leveraging an experimental network of land-based and in-lake mesocosms across North America and Europe, we tested how salinization—indicated as elevated chloride (Cl2) concentration—will affect lake food webs and if two of the lowest Cl2 thresholds found globally are sufficient to protect these food webs. Our results indicated that salinization will cause substantial …
Ungulates Alter Plant Cover Without Consistent Effect On Soil Ecosystem Functioning, Miguel Ibañez-Alvarez, Elena Baraza, Emmanuel Serrano, Antonia Romero-Munar, Carles Cardona, Jordi Bartolome, Jennifer Adams Krumins
Ungulates Alter Plant Cover Without Consistent Effect On Soil Ecosystem Functioning, Miguel Ibañez-Alvarez, Elena Baraza, Emmanuel Serrano, Antonia Romero-Munar, Carles Cardona, Jordi Bartolome, Jennifer Adams Krumins
Department of Biology Faculty Scholarship and Creative Works
Shifts in animal husbandry and landscape use have significantly changed ungulate grazing effects on ecosystem functioning. These changes are now the subject of extensive research with respect to plant and soil communities, but the results of these studies are highly varied and context dependent. The objective of this study is to address contextual variation by holding all sampling methods and analytical approaches constant and analyse the effect of the feral goat (Capra hircus) population of Mallorca Island, Spain, on soil physical, chemical and biological characteristics across five controlled sites. Specifically, vegetation cover and soil properties in fenced plots excluded from …
The Coxsackievirus And Adenovirus Receptor Has A Short Half-Life In Epithelial Cells, Poornima Kotha Lakshmi Narayan, James M. Readler, Mahmoud S. Alghamri, Trisha L. Brockman, Ray Yan, Priyanka Sharma, Vladislav Snitsarev, Katherine J.D.A Excoffon, Abimbola O. Kolawole
The Coxsackievirus And Adenovirus Receptor Has A Short Half-Life In Epithelial Cells, Poornima Kotha Lakshmi Narayan, James M. Readler, Mahmoud S. Alghamri, Trisha L. Brockman, Ray Yan, Priyanka Sharma, Vladislav Snitsarev, Katherine J.D.A Excoffon, Abimbola O. Kolawole
Department of Biology Faculty Scholarship and Creative Works
The coxsackievirus and adenovirus receptor (CAR) is an essential cellular protein that is involved in cell adhesion, cell signaling, and viral infection. The 8-exon encoded isoform (CAREx8) resides at the apical surface of polarized epithelia, where it is accessible as a receptor for adenovirus entering the airway lumen. Given its pivotal role in viral infection, it is a target for antiviral strategies. To understand the regulation of CAREx8 and determine the feasibility of receptor down regulation, the half-life of total and apical localized CAREx8 was determined and correlated with adenovirus transduction. Total and apical CAREx8 has a relatively short half-life …
Self-Conscious Emotions And The Right Fronto-Temporal And Right Temporal Parietal Junction, Adriana Lavarco, Nathira Ahmad, Qiana Archer, Matthew Pardillo, Ray Nunez Castaneda, Anthony Minervini, Julian Keenan
Self-Conscious Emotions And The Right Fronto-Temporal And Right Temporal Parietal Junction, Adriana Lavarco, Nathira Ahmad, Qiana Archer, Matthew Pardillo, Ray Nunez Castaneda, Anthony Minervini, Julian Keenan
Department of Biology Faculty Scholarship and Creative Works
For more than two decades, research focusing on both clinical and non-clinical populations has suggested a key role for specific regions in the regulation of self-conscious emotions. It is speculated that both the expression and the interpretation of self-conscious emotions are critical in humans for action planning and response, communication, learning, parenting, and most social encounters. Empathy, Guilt, Jealousy, Shame, and Pride are all categorized as self-conscious emotions, all of which are crucial components to one’s sense of self. There has been an abundance of evidence pointing to the right Fronto-Temporal involvement in the integration of cognitive processes underlying the …
A Gene-Based Capture Assay For Surveying Patterns Of Genetic Diversity And Insecticide Resistance In A Worldwide Group Of Invasive Mosquitoes, Matthew L. Aardema, Michael G. Campana, Nicole E. Wagner, Francisco C. Ferreira, Dina M. Fonseca
A Gene-Based Capture Assay For Surveying Patterns Of Genetic Diversity And Insecticide Resistance In A Worldwide Group Of Invasive Mosquitoes, Matthew L. Aardema, Michael G. Campana, Nicole E. Wagner, Francisco C. Ferreira, Dina M. Fonseca
Department of Biology Faculty Scholarship and Creative Works
Understanding patterns of diversification, genetic exchange, and pesticide resistance in arthropod disease vectors is necessary for effective population management. With the availability of next-generation sequencing technologies, one of the best approaches for surveying such patterns involves the simultaneous genotyping of many samples for a large number of genetic markers. To this end, the targeting of gene sequences of known function can be a cost-effective strategy. One insect group of substantial health concern are the mosquito taxa that make up the Culex pipiens complex. Members of this complex transmit damaging arboviruses and filariae worms to humans, as well as other pathogens …
Assessment Of Digital Imaging Flow Cytometry In Its Application Of Harmful Algal Blooms Monitoring, Melissa Mazzaro
Assessment Of Digital Imaging Flow Cytometry In Its Application Of Harmful Algal Blooms Monitoring, Melissa Mazzaro
Theses, Dissertations and Culminating Projects
As harmful algal blooms (HABs) are becoming an increasing global threat to the health of people, animals, and aquatic ecosystems, finding ways to efficiently detect and manage blooms is critical. Traditional methods of identifying and enumerating phytoplankton cells involve light microscopy; however, this is a time-consuming and labor-intensive process. Meanwhile, digital imaging flow cytometry is a relatively novel and rapid method of enumerating and identifying particles within phytoplankton samples. Previous studies have documented comparable digital flow cytometry results to microscopy results; however, there are concerns relating to the underestimation of cells and misidentification of particles with their automated classification systems. …