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- Biological sciences (2)
- Circular dichroism (2)
- Pure sciences (2)
- Biophysical (1)
- C2 domain (1)
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- Cell adhesion (1)
- Chromosome polymorphism (1)
- DNA microarrays -- Research (1)
- Differential scanning calorimetry (1)
- Gene cloning (1)
- Gene synthesis (1)
- Nucleic acid hybridization (1)
- Porphyrin (1)
- Potassium (1)
- Quadruplexes (1)
- Research infrastructure improvement (1)
- Telomeres (1)
- Tensin (1)
- Thermal stability (1)
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Articles 1 - 5 of 5
Full-Text Articles in Biophysics
Gene Synthesis, Cloning, Expression, Purification And Biophysical Characterization Of The C2 Domain Of Human Tensin, Kiran Sukumar Gajula
Gene Synthesis, Cloning, Expression, Purification And Biophysical Characterization Of The C2 Domain Of Human Tensin, Kiran Sukumar Gajula
Doctoral Dissertations
Tensin is a large "docking" protein found in the adhesive junctions of animal cells and recruited early in the development of cell-substrate contacts. There it binds to the cytoplasmic domain of integrin β1 and caps the barbed ends of filamentous actin. This forms a rational basis for its implication in a direct role in the mechanics of membrane-cytoskeleton interactions. Tensin provides a physical link between the actin cytoskeleton, integrins, and other proteins at the cell-substrate contacts. Its overall biochemical properties are a function of its domain composition and architecture, i.e., the domains that are present and their relative positions in …
Establishing Research Competitiveness In Biophysical Sciences In Maine, Michael Eckardt, Rosemary Smith, Barbara Knowles, Michael Grunze, Deirdre Mageean, Scott Collins, Heather Almquist, Robert Friesel, Thomas Maciag
Establishing Research Competitiveness In Biophysical Sciences In Maine, Michael Eckardt, Rosemary Smith, Barbara Knowles, Michael Grunze, Deirdre Mageean, Scott Collins, Heather Almquist, Robert Friesel, Thomas Maciag
University of Maine Office of Research Administration: Grant Reports
The Maine EPSCoR Research Infrastructure Improvement award is designed to enhance Maine's competitiveness in molecular biophysical sciences through a partnership between the University of Maine and Maine's non-profit research organizations. The proposed Biophysical Sciences Institute brings together University of Maine faculty in physics, chemistry, biology, mathematics, and spatial engineering, with biomedical researchers at the Jackson Laboratory and Maine Medical Center Research Institute. Maine EPSCoR proposes to hire additional tenure-track faculty in the fields of biophysics and advanced optics, biochemistry, structural biology, applied mathematics, computer science, image analysis and visualization, and material science. The new and existing investigators will form research …
Multiplex Snp Discrimination, Daniel J. Fish, M. Todd Horne, Robert P. Searles, Greg P. Brewood, Albert S. Benight
Multiplex Snp Discrimination, Daniel J. Fish, M. Todd Horne, Robert P. Searles, Greg P. Brewood, Albert S. Benight
Chemistry Faculty Publications and Presentations
Multiplex hybridization reactions of perfectly matched duplexes and duplexes containing a single basepair mismatch (SNPs) were investigated on DNA microarrays. Effects of duplex length, G-C percentage, and relative position of the SNP on duplex hybridization and SNP resolution were determined. Our theoretical model of multiplex hybridization accurately predicts observed results and implicates target concentration as a critical variable in multiplex SNP detection.
Effects Of Molecular Motion On Deuteron Magic Angle Spinning Nmr Spectra, Yuanyuan Huang
Effects Of Molecular Motion On Deuteron Magic Angle Spinning Nmr Spectra, Yuanyuan Huang
Dissertations, Theses, and Masters Projects
Solid state deuteron NMR experiments, especially magic angle spinning (MAS) and off-magic angle spinning (OMAS), are developed to explore dynamical systems. A theoretical discussion of interactions relevant for spin-1 nuclei is presented. Practical aspects of MAS/OMAS experiments are described an detail. The dominant quadrupolar coupling interaction in deuteron NMR has been simulated and the effects of multiple-frame molecular motions on MAS/OMAS spectra are taken into account in this calculation. Effects of chemical shift anisotropy are also simulated, and shown to be small under conditions of rapid sample spinning.;Two numerical methods, direct integration and an efficient simulation routine based on Floquet …
The Biophysical Analysis Of The Human Telomeric Repeat (Ttaggg)4 And Characterization Of Porphyrin Binding In Potassium Solutions, Cosimo Antonacci
The Biophysical Analysis Of The Human Telomeric Repeat (Ttaggg)4 And Characterization Of Porphyrin Binding In Potassium Solutions, Cosimo Antonacci
Seton Hall University Dissertations and Theses (ETDs)
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