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Genetics and Genomics

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Full-Text Articles in Dairy Science

Derivation Of The Maintenance Energy Requirements In Growing Jersey Heifers: Supplementary Table S1, Addison L. Carroll, Michael J. Vandehaar, Paul J. Kononoff Jan 2025

Derivation Of The Maintenance Energy Requirements In Growing Jersey Heifers: Supplementary Table S1, Addison L. Carroll, Michael J. Vandehaar, Paul J. Kononoff

Department of Animal Science: Faculty Publications

Supplemental table for Addison L. Carroll, Michael J. VandeHaar, and Paul J. Kononoff. Derivation of the maintenance energy requirements in growing Jersey heifers. Journal of Dairy Science (2025).


Increased Coding Potential Of Bovine Herpesvirus 1, Victoria Jefferson Dec 2023

Increased Coding Potential Of Bovine Herpesvirus 1, Victoria Jefferson

Theses and Dissertations

Bovine respiratory disease (BRD) costs the cattle industry millions of dollars in costs in treatment and loss every year in the United States. A significant pathogen often contributes to BRD is Bovine Herpesvirus 1 (BoHV-1), a double stranded DNA virus with the ability to establish latency in the trigeminal ganglia and neurons. Primary infection with BoHV-1 results in immunosuppression that increases the risk of secondary bacterial infection and pneumonia. Because herpesviruses infect their hosts for life and can be reactivated in times of stress, BoHV-1 can present a recurring risk of BRD. The following research aims to expand the knowledge …


Characterisation Of Sex Chromosome Aneuploidy In Female Cattle Using Genotype Information, Cliona Ryan Nov 2023

Characterisation Of Sex Chromosome Aneuploidy In Female Cattle Using Genotype Information, Cliona Ryan

ORBioM (Open Research BioSciences Meeting)

Background

Aneuploidy is a genetic condition characterized by the loss (monosomy) or gain (trisomy) of one or more chromosomes. Aneuploidy affecting the sex chromosomes often leads to infertility. The objective of this study was to estimate the prevalence of sex chromosome aneuploidy in a large juvenile population using routinely available genotype intensity information.

Methods

Genotype and genotype intensity data was available on 145,476 female dairy and beef cattle below 15 months of age at the time of genotyping, with no recorded progeny. Genotype intensity data included the LogR Ratio (LRR), R-value (the sum of X and Y SNP probe intensities), …


The Investigation Of Novel Bovine Oocyte-Specific Long Non-Coding Rnas And Their Roles In Oocyte Maturation And Early Embryonic Development, Jaelyn Zoe Current Jan 2023

The Investigation Of Novel Bovine Oocyte-Specific Long Non-Coding Rnas And Their Roles In Oocyte Maturation And Early Embryonic Development, Jaelyn Zoe Current

Graduate Theses, Dissertations, and Problem Reports (ETD)

Early embryonic loss is a significant factor in livestock species' infertility, resulting in an economic deficit. In cattle, the in vivo fertilization rate is ~90%, with an average calving rate of about 55%, indicating an embryonic-fetal mortality rate of roughly 35%. Further, 70-80% of total embryonic loss in cattle occurs during the first three weeks after insemination, particularly between days 7-16. Growing evidence indicates that the oocyte plays an active role in regulating critical aspects of the reproductive process required for successful fertilization, embryo development, and pregnancy. However, defining oocyte quality remains enigmatic. Recently, many have abandoned the notion that …


Genetic Variations In The Myostatin Gene Among Irish Cattle Breeds, Cliona Ann Ryan Jun 2022

Genetic Variations In The Myostatin Gene Among Irish Cattle Breeds, Cliona Ann Ryan

ORBioM (Open Research BioSciences Meeting)

No abstract provided.


Primary Industries Development Research Highlights 2021, Department Of Primary Industries And Regional Development, Tim Scanlon Aug 2021

Primary Industries Development Research Highlights 2021, Department Of Primary Industries And Regional Development, Tim Scanlon

Books & book chapters

The Primary Industries Development Research Highlights 2021 showcases the breadth and depth of the Department of Primary Industries and Regional Development’s research and development activities over the past several years.

Stories featured in Research Highlights 2021 stem from about 60 (of 140) current and recently-completed projects undertaken by the Department of Primary Industries and Regional Development’s (DPIRD) 1100 scientists, technical experts and economists throughout the State.

Explore our Research Highlights 2021.

The publication demonstrates the innovative and applicable research that DPIRD and its collaborators and investment partners deliver to Western Australia.

Download the Research Highlights 2021 here. Alternatively, …


The Effect Of Bovine Galectin-1, A Conceptus Secretory Protein, On The Endometrial Transcriptome, Lindsay Faye Grose Jan 2019

The Effect Of Bovine Galectin-1, A Conceptus Secretory Protein, On The Endometrial Transcriptome, Lindsay Faye Grose

Graduate Theses, Dissertations, and Problem Reports (ETD)

Early embryonic loss in cattle is detrimental to reproduction thus, the profitability of both the beef and dairy industries. Therefore, an important aspect of study is to find techniques that beef or dairy producers could use to decrease early embryonic loss Galectin-1, the protein that was investigated in this research is important in modulating the maternal immune system in rodent and human early pregnancies by promoting fetomaternal immune tolerance. The role of galectin-1 within the reproductive tissues has not been thoroughly investigated in cattle. Galectin-1 is located in the caruncular and intercaruncular regions of the bovine endometrium, specifically the maternal …


Comparing Strategies For Selection Of Low-Density Snps For Imputation-Mediated Genomic Prediction In U.S. Holsteins, Jun He, Jiaqi Xu, Xiao-Lin Wu, Stewart Bauck, Jungjae Lee, Gota Morota, Stephen D. Kachman, Matthew L. Spangler Dec 2018

Comparing Strategies For Selection Of Low-Density Snps For Imputation-Mediated Genomic Prediction In U.S. Holsteins, Jun He, Jiaqi Xu, Xiao-Lin Wu, Stewart Bauck, Jungjae Lee, Gota Morota, Stephen D. Kachman, Matthew L. Spangler

Department of Animal Science: Faculty Publications

SNP chips are commonly used for genotyping animals in genomic selection but strategies for selecting low-density (LD) SNPs for imputation-mediated genomic selection have not been addressed adequately. The main purpose of the present study was to compare the performance of eight LD (6K) SNP panels, each selected by a different strategy exploiting a combination of three major factors: evenly-spaced SNPs, increased minor allele frequencies, and SNP-trait associations either for single traits independently or for all the three traits jointly. The imputation accuracies from 6K to 80K SNP genotypes were between 96.2 and 98.2%. Genomic prediction accuracies obtained using imputed 80K …


Characterization Of An N-Terminal Non-Core Domain Of Rag1 Gene Disrupted Syrian Hamster Model Generated By Crispr Cas9, Jinxin Miao, Baoling Ying, Rong Li, Ann E. Tollefson, Jacqueline F. Spencer, William S.M. Wold, Seok-Hwan Song, Il-Keun Kong, Karoly Toth, Yaohe Wang, Zhongde Wang May 2018

Characterization Of An N-Terminal Non-Core Domain Of Rag1 Gene Disrupted Syrian Hamster Model Generated By Crispr Cas9, Jinxin Miao, Baoling Ying, Rong Li, Ann E. Tollefson, Jacqueline F. Spencer, William S.M. Wold, Seok-Hwan Song, Il-Keun Kong, Karoly Toth, Yaohe Wang, Zhongde Wang

Animal, Dairy, and Veterinary Science Faculty Publications

The accumulating evidence demonstrates that Syrian hamsters have advantages as models for various diseases. To develop a Syrian hamster (Mesocricetus auratus) model of human immunodeficiency caused by RAG1 gene mutations, we employed the CRISPR/Cas9 system and introduced an 86-nucleotide frameshift deletion in the hamster RAG1 gene encoding part of the N-terminal non-core domain of RAG1. Histological and immunohistochemical analyses demonstrated that these hamsters (referred herein as RAG1-86nt hamsters) had atrophic spleen and thymus, and developed significantly less white pulp and were almost completely devoid of splenic lymphoid follicles. The RAG1-nt86 hamsters had barely detectable CD3+ and CD4+ T cells. The …


Low Cost, Multi-Purpose Genotyping Panels For Dairy And Beef Cattle, Michelle Judge Jan 2017

Low Cost, Multi-Purpose Genotyping Panels For Dairy And Beef Cattle, Michelle Judge

Theses

rhe selection of animals based on DNA has revolutionised animal breeding, but the associated high cost of obtaining genotypes has limited its uptake. The objective of this thesis was to develop a low-cost, low-density, multi-purpose genotyping panel for the procurement of reliable genotype information, and to quantify the long-term consequences of using such low-density genotype panels in breeding programs. The objectives were achieved through a combination of real-life cattle genotype data and simulations to mimic a cattle population. The in-silico development of genotype panels was based on actual genotypes from up to 58,705 beef cattle. Alternative novel strategies were used …


Genetic Polymorphisms Of The Glucocorticoid Receptor And Interleulin-8 Receptor Genes And Their Relationship To Production Traits And Hair Coat Scores In Crossbred Cattle, Avery B. Deaton, Laura Meyer, Jeremy Powell, Charles F. Rosenkrans Jr. Jan 2017

Genetic Polymorphisms Of The Glucocorticoid Receptor And Interleulin-8 Receptor Genes And Their Relationship To Production Traits And Hair Coat Scores In Crossbred Cattle, Avery B. Deaton, Laura Meyer, Jeremy Powell, Charles F. Rosenkrans Jr.

Discovery, The Student Journal of Dale Bumpers College of Agricultural, Food and Life Sciences

Little is understood about how the diversity of genes, specifically the glucocorticoid receptor (GR) and interleukin-8 receptor (CXCR2), are related to reproductive health and how this affects physical traits in cattle. Glucocorticoid receptors have been positively associated with higher milk yields, lactose content, feed intake, and feed conversion rates. Interleukin-8 genes are part of the innate immune response and help with many aspects of female reproductive health, such as protecting the embryo from the maternal immune system during pregnancy. The objective of this research was to identify polymorphisms in the GR and CXCR2 genes and to associate genotypes between the …


A Tail Of Two Phages: Genomic And Functional Analysis Of Listeria Monocytogenes Phages Vb_Lmos_188 And Vb_Lmos_293 Reveal The Receptor-Binding Proteins Involved In Host Specificity, Aidan Casey, Kieran Jordan, Horst Neve, Aidan Coffey, Olivia Mcauliffe Oct 2015

A Tail Of Two Phages: Genomic And Functional Analysis Of Listeria Monocytogenes Phages Vb_Lmos_188 And Vb_Lmos_293 Reveal The Receptor-Binding Proteins Involved In Host Specificity, Aidan Casey, Kieran Jordan, Horst Neve, Aidan Coffey, Olivia Mcauliffe

Department of Biological Sciences Publications

The physical characteristics of bacteriophages establish them as viable candidates for downstream development of pathogen detection assays and biocontrol measures. To utilize phages for such purposes, a detailed knowledge of their host interaction mechanisms is a prerequisite. There is currently a wealth of knowledge available concerning Gram-negative phage-host interaction, but little by comparison for Gram-positive phages and Listeria phages in particular. In this research, the lytic spectrum of two recently isolated Listeria monocytogenes phages (vB_LmoS_188 and vB_LmoS_293) was determined, and the genomic basis for their observed serotype 4b/4e host-specificity was investigated using comparative genomics. The late tail genes of these …


Choline And Choline Metabolite Patterns And Associations In Blood And Milk During Lactation In Dairy Cows, Virginia M. Artegoitia, Jesse L. Foote, Federico M. Harte, Shawn R. Campagna, Michael J. De Veth Aug 2014

Choline And Choline Metabolite Patterns And Associations In Blood And Milk During Lactation In Dairy Cows, Virginia M. Artegoitia, Jesse L. Foote, Federico M. Harte, Shawn R. Campagna, Michael J. De Veth

Department of Animal Science: Faculty Publications

Milk and dairy products are an important source of choline, a nutrient essential for human health. Infant formula derived from bovine milk contains a number of metabolic forms of choline, all contribute to the growth and development of the newborn. At present, little is known about the factors that influence the concentrations of choline metabolites in milk. The objectives of this study were to characterize and then evaluate associations for choline and its metabolites in blood and milk through the first 37 weeks of lactation in the dairy cow. Milk and blood samples from twelve Holstein cows were collected in …


Sire Evaluation For Milking Duration, James Macedo Mar 2013

Sire Evaluation For Milking Duration, James Macedo

Dairy Science

The objective of this study was to utilize electronically recorded data from on-farm milk recording systems and herd management software to determine if a sire has a genetic influence on his daughter’s milking duration. Measurements of milking duration from three dairy facilities were taken between January 27, 2013 and January 31, 2013. These measurements supplied 25,070 observations, corresponding to 9,418 cows and 895 sires. These data were evaluated with a SAS alongside a herd-mate comparison. The statistical analysis demonstrated that a sire does have a genetic influence on the milking duration of his progeny. The Van Beek Brothers and Dairyland …


Intsormil- Centa’S New Bmr Sorghum Varieties Create A Surge In Dairy Production, René Clará Valencia Nov 2012

Intsormil- Centa’S New Bmr Sorghum Varieties Create A Surge In Dairy Production, René Clará Valencia

INTSORMIL Scientific Publications

Scientists from the INTSORMIL-CENTA project based at the National Center for Agricultural Technology and Forestry (CENTA) of El Salvador have worked for five years to develop varieties of sorghum for grain and forage that are highly nutritious to cattle. Using the gene bmr-12, received from Dr. Gebisa Ejeta of Purdue University, they combined commercial varieties CENTA S-2, S-3 CENTA, CENTA RCV and VG 146 and were able to form new varieties containing this same gene. The first generation created 76 new varieties.


Selecting, Marketing And Rebuilding A Herd Of Genetically Superior Animals, Katherine Rector Dec 2009

Selecting, Marketing And Rebuilding A Herd Of Genetically Superior Animals, Katherine Rector

Dairy Science

No abstract provided.


Letter From The Dean, Lalit Verma Jan 2009

Letter From The Dean, Lalit Verma

Discovery, The Student Journal of Dale Bumpers College of Agricultural, Food and Life Sciences

No abstract provided.


Herd Improvement Service Forges Ahead, M P. Bond Jan 1987

Herd Improvement Service Forges Ahead, M P. Bond

Journal of the Department of Agriculture, Western Australia, Series 4

Since its establishment three years ago, the Herd Improvement Service has steadily expanded the range of services provided to Western Australian livestock producers. The genetic advancement and improved hers management offered by the service give farmers the ability to use modern technology in the most cost-effective way. There is an increasing realisation amongst farmers that to survive and remain competitive, it is worthwhile to invest in such technology.

The Herd Improvement Service is a statutory corporation which was formed to improve the productivity of the State's livestock enterprises. Most of the organisation's activities have been directed to servicing the dairy …


Subject And Author Index For Bulletins Of The Storrs Agricultural Experiment Station, Mohini Mundkur May 1979

Subject And Author Index For Bulletins Of The Storrs Agricultural Experiment Station, Mohini Mundkur

Storrs Agricultural Experiment Station

Storrs Agricultural Experiment Station Bulletin #453, 68 pages.


Research For Connecticut By The Storrs Agricultural Experiment Station Sep 1977

Research For Connecticut By The Storrs Agricultural Experiment Station

Storrs Agricultural Experiment Station

No abstract provided.


Cancer Eye Of Cattle, M R. Gardiner, J. L. Anderson, D. E. Robertson Jan 1972

Cancer Eye Of Cattle, M R. Gardiner, J. L. Anderson, D. E. Robertson

Journal of the Department of Agriculture, Western Australia, Series 4

Cancer of the eye and eyelids is mainly a disease of cattle, although it occasionally occurs in most species of animals and in man. It is the most common cancer in cattle, especially in certain breeds.


Meat From The Dairy Herd, R A. Bettenay Jan 1972

Meat From The Dairy Herd, R A. Bettenay

Journal of the Department of Agriculture, Western Australia, Series 4

Beef raising is a profitable sideline for many West Australian dairy farmers and gives their farming operation flexibility and versatility.

With suitable management and feeding the weight gains and consumer acceptance of dairy beef allow it to compete strongly with beef from other sources.

The breeds most common on W.A. dairy farms are well suited to beef production.


Methods Of Cattle Identification For The Farmer, R C. Burking Jan 1971

Methods Of Cattle Identification For The Farmer, R C. Burking

Journal of the Department of Agriculture, Western Australia, Series 4

THE value of management decisions in day-to-day dairy herd management, such as breeding, selection, and culling, depends on accurate identification of individual animals.

A report on tests of some methods of cattle identification available to farmers.

This article is concerned only with methods of identification of cattle on the farm. It is the farmer's responsibility to brand his stock with his registered brand to comply with the requirements of the Brands Act, in addition to any brands or tags applied for his own management purposes.

Any marks other than the registered brand or earmark must be clearly distinguishable from, and …


Birth Weights Of Calves : Report Of A Calf Weighing Project At Wokalup Research Station, Maurice C. Cullity Jan 1969

Birth Weights Of Calves : Report Of A Calf Weighing Project At Wokalup Research Station, Maurice C. Cullity

Journal of the Department of Agriculture, Western Australia, Series 4

SINCE 1957, all calves born on Wokalup Research Station have been weighed as close to b i r th as possible and detailed birth weight records have been kept for all phases of the Station's breeding activities.


Grade Herd Recording : 1962-63, Maurice C. Cullity Jan 1963

Grade Herd Recording : 1962-63, Maurice C. Cullity

Journal of the Department of Agriculture, Western Australia, Series 4

A poor season coupled with a 16 per cent, increase in the number of cows tested during 1962-63 led to a drop in the average yields of cows in the Grade Herd Recording Scheme.


Selection Of Dairy Heifers, Department Of Agriculture, Western Australia Jan 1962

Selection Of Dairy Heifers, Department Of Agriculture, Western Australia

Journal of the Department of Agriculture, Western Australia, Series 4

THE time is approaching on most dairy farms when a decision has to be made on which of the year's crop of heifers are to be retained.

Replacements are needed not only to keep up herd numbers, but also to increase the average production.

This is herd improvement—surely the aim of all dairy farmers.


Identical Twins, Department Of Agriculture, Western Australia Jan 1961

Identical Twins, Department Of Agriculture, Western Australia

Journal of the Department of Agriculture, Western Australia, Series 4

THE response to the Department's appeal for identical twin calves has been gratifying, and so far this year five sets have been located and collected.

In view of the rare occurrence of identical twinning, this indicates excellent co-operation from dairy farmers.


Selecting A Herd Sire, R A. Bettenay Jan 1961

Selecting A Herd Sire, R A. Bettenay

Journal of the Department of Agriculture, Western Australia, Series 4

THERE is now ample evidence that most of the differences in production between herds are determined by feeding and management, with differences in genetic merit playing a relatively minor role.

It seems that the quickest way to increase production is by improved feeding, whilst in some herds much production is being lost by faulty milking techniques.


Identicial Twins : A Valuable Aid To Animal Husbandry Research, Department Of Agriculture, Western Australia Jan 1961

Identicial Twins : A Valuable Aid To Animal Husbandry Research, Department Of Agriculture, Western Australia

Journal of the Department of Agriculture, Western Australia, Series 4

A T a recent field day at Wokalup Research Station a set of identical twins was shown as being the start of a project to build up a herd or number of such, for research and extension work.


The Problem Of Low Solids-Not-Fat In Milk, Laurence C. Snook Jan 1960

The Problem Of Low Solids-Not-Fat In Milk, Laurence C. Snook

Journal of the Department of Agriculture, Western Australia, Series 4

TO the consumer of milk, the solids-not-fat fractions is of prime importance.

This contains the protein, the minerals and the milk-sugar which collectively make milk such a valuable and palatable food.

If we wish to encourage increased consumption of milk as a health food it is essential that quality must be maintained and if possible improved.

Producers and distributors must always remember that if maximum sales are to be obtained, the needs of the consumer must remain paramount.