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Articles 5671 - 5700 of 6737
Full-Text Articles in Life Sciences
Warm Mix Asphalt: Key Issues, Performance Challenges, And Modeling Advances, Mahmoud Owais, Marwa Awad
Warm Mix Asphalt: Key Issues, Performance Challenges, And Modeling Advances, Mahmoud Owais, Marwa Awad
Mansoura Engineering Journal
Warm Mix Asphalt (WMA) has emerged as a sustainable alternative to conventional Hot Mix Asphalt by enabling asphalt production and compaction at reduced temperatures, thereby lowering energy consumption, emissions, and worker exposure to heat and fumes. Despite these advantages, the field performance of WMA remains influenced by technology-specific mechanisms, additive–binder compatibility, aggregate characteristics, moisture susceptibility, compaction quality, recycled material content, and climatic conditions. This review provides a critical synthesis of major WMA technologies, including foamed systems, chemical additives, organic waxes, hybrid additives, bio-based modifiers, and WMA mixtures incorporating reclaimed asphalt pavement. Particular attention is given to how these technologies affect …
Reliability-Oriented Spatiotemporal Machine Learning For High-Impact Power Outage Event Prediction, Marwa Gamal
Reliability-Oriented Spatiotemporal Machine Learning For High-Impact Power Outage Event Prediction, Marwa Gamal
Mansoura Engineering Journal
Power outages have become an increasing concern for modern power systems due to their impact on infrastructure reliability, economic activities, and public safety. The growing frequency of extreme weather events and the rising demand for electricity have made it more difficult to anticipate high-impact outage events. One of the main challenges in this context is the complex interaction between temporal patterns and geographic variations, which traditional methods often fail to capture effectively. This study develops a machine learning framework that combines temporal characteristics with geographic information to improve the prediction of high-impact power outages. Temporal features such as seasonal patterns, …
A Hybrid Geospatial And Remote Sensing Methodology For Drought Vulnerability Assessment In Semi-Arid Ecosystems, Kaifi Fakhir Chomani
A Hybrid Geospatial And Remote Sensing Methodology For Drought Vulnerability Assessment In Semi-Arid Ecosystems, Kaifi Fakhir Chomani
Mansoura Engineering Journal
The Kurdistan Region of Iraq (KRI) faced significant drought challenges due to global and environmental changes, necessitating drought assessments. Advanced techniques of remote sensing, Geographic Information Systems (GIS), and Analytic Hierarchy Process (AHP) were combined in this research to perform drought vulnerability zonation for KRI. Average annual rainfall, Average number of rainy days, Average annual temperature, slope, elevation, normalised difference water index (NDWI), normalised difference vegetation index (NDVI), land surface temperature (LST), and temperature condition index (TCI) were selected as contributing parameters for drought vulnerability assessments. The considered parameters were weighted using pairwise comparison, and thematic maps were created to …
Psychological Impact Of Cultural Heritage Vr Experience Using Well-Mind Framework. (Case Study: Mahmoud Sami Palace In Mansoura)., Sara Ahmed El-Bayoumi, Hager Ahmed El-Sayed El-Ayouti, Mohamed Mohamed Shawki Abo Leila
Psychological Impact Of Cultural Heritage Vr Experience Using Well-Mind Framework. (Case Study: Mahmoud Sami Palace In Mansoura)., Sara Ahmed El-Bayoumi, Hager Ahmed El-Sayed El-Ayouti, Mohamed Mohamed Shawki Abo Leila
Mansoura Engineering Journal
This study examines the psychological effects of immersive virtual reality (VR) experiences designed to preserve and disseminate intangible cultural heritage. It addresses the growing challenge of declining cultural engagement and the need for innovative tools that support psychological well-being, emotional engagement, and cultural connection. A VR-based reconstruction was developed within the historic Mahmoud Sami Al-Baroudi Palace in Mansoura, Egypt, focusing on traditional Egyptian practices and oral storytelling. The evaluation employed the WELL-MIND framework alongside participant feedback to assess both structured well-being indicators and subjective user experiences. The WELL-MIND-based assessment indicated improvements in cognitive stimulation, emotional engagement, and environmental perception. In …
Control Of Steel Corrosion Using Natural Corrosion Inhibitor, Rasha A. Nasef, O. Hamed, M. M. El-Halwany, M. H. Mahmoud
Control Of Steel Corrosion Using Natural Corrosion Inhibitor, Rasha A. Nasef, O. Hamed, M. M. El-Halwany, M. H. Mahmoud
Mansoura Engineering Journal
This study investigates corrosion control of AISI 430 stainless steel in 1M HCl medium using an eco-friendly inhibitor extracted from pomegranate peel (PPE). The inhibition efficiency was evaluated at different PPE concentrations, with the highest applied concentration of 13g/L. Corrosion behavior was evaluated through weight-loss measurements and potentiodynamic polarization techniques conducted at room temperature.
The experimental results showed that corrosion resistance improved as the inhibitor concentration increased. Lower corrosion rates were observed in the presence of PPE, along with reduced anodic and cathodic activities, indicating that the extract functions as a mixed-type inhibitor. Surface analysis confirmed the formation of …
Optimal Design Of Concrete Canal Section For Minimizing Overall Costs Using Artificial Ecosystem Optimization, Aya M. Elkhouly, Hamdy A. El-Ghandour, Tharwat Sarhan, Mahmoud E. Abd-Elmaboud
Optimal Design Of Concrete Canal Section For Minimizing Overall Costs Using Artificial Ecosystem Optimization, Aya M. Elkhouly, Hamdy A. El-Ghandour, Tharwat Sarhan, Mahmoud E. Abd-Elmaboud
Mansoura Engineering Journal
The optimal design of concrete-lined canals represents a critical challenge in hydraulic engineering, requiring simultaneous minimization of construction and operational costs while satisfying hydraulic performance constraints. This study presents a novel optimization framework that utilizes the Artificial Ecosystem-based Optimization (AEO) algorithm for determining optimal canal cross-sectional dimensions. The proposed methodology comprehensively considers excavation costs, lining expenses, and water losses due to seepage and evaporation while ensuring hydraulic efficiency through velocity and Froude number constraints. The AEO algorithm mimics natural ecosystem processes through production, consumption, and decomposition phases to efficiently explore the design space and converge to global optima. The framework …
Optimization Of Mechanical Properties Of Copper Nanofiller Reinforced Banana Fiber Polyester Composites Using Grey–Taguchi Method, Nikhil Janardan Rathod, Mayur Jayant Gitay, Markala Karthik, Harshwardhan Ghongade, Upendra Rajak, Rajendra Sopan Narkhede
Optimization Of Mechanical Properties Of Copper Nanofiller Reinforced Banana Fiber Polyester Composites Using Grey–Taguchi Method, Nikhil Janardan Rathod, Mayur Jayant Gitay, Markala Karthik, Harshwardhan Ghongade, Upendra Rajak, Rajendra Sopan Narkhede
Mansoura Engineering Journal
Mechanical performance of banana fiber-reinforced polyester composites maximized using a composite Taguchi and a Grey Relational Analysis (GRA) process. This will aim at enhancing dispensation limits to enhance better tensile, flexural and impact belongings. The hand lay-up method was used to create composites by variable three key limits and they included banana fiber content (30 wt%), copper nanoparticle content (15 wt%), and curing temperature (80 o C). Trial design and mechanical properties were being measured in form of ASTM values on a L9 orthogonal array.
The multi-response optimization was performed with the help of the Grey Relational Analysis, which was …
Self-Lubricating Nano-Coatings For Tribological Applications: Materials, Mechanisms, And Ai-Driven Design Approaches, Viral Panara, Vikas Panchal, Satayu Travadi, Harmish Bhatt, Madhav Oza
Self-Lubricating Nano-Coatings For Tribological Applications: Materials, Mechanisms, And Ai-Driven Design Approaches, Viral Panara, Vikas Panchal, Satayu Travadi, Harmish Bhatt, Madhav Oza
Mansoura Engineering Journal
Self-lubricating coatings with nanostructured structures are becoming crucial in order to decrease friction and wear in critical tribological systems like precision tools, biomedical implants, aerospace actuators, and engines. In this review, the most representative nano-engineered solid lubricants such as transition metal dichalcogenides, diamond-like carbon, hexagonal boron nitride, graphene, MXenes and hybrid multilayer architectures are discussed. The focus of the discussion is on the most important tribological mechanisms like lamellar sliding, oxidative adaptation, tribofilm formation, transfer-film development, and nano-asperity contact evolution. It also summarizes the most significant deposition techniques, such as cathodic arc physical vapor deposition, chemical vapor deposition, plasma-based deposition, …
Construction-Phase Leed Compliance In Egypt: Development Of A Rule-Based Expert System For Contractor Decision Support, Mohamed R. Ahmed, Atef A. Ragab, Sameh Y. Mahfouz
Construction-Phase Leed Compliance In Egypt: Development Of A Rule-Based Expert System For Contractor Decision Support, Mohamed R. Ahmed, Atef A. Ragab, Sameh Y. Mahfouz
Mansoura Engineering Journal
This study develops a rule-based expert system implemented in Python to support contractors in achieving LEED BD+C: New Construction v4 certification during the construction phase in Egypt. The research identifies and validates construction-phase obstacles affecting LEED compliance through a structured questionnaire targeting building contractors in Egypt. The questionnaire process was conducted in two stages: a pilot survey was used to screen and refine the initially identified obstacles, while the main survey was used to validate the practical relevance of the retained obstacles within the Egyptian construction context. In parallel, the study analyzes construction-phase prerequisites and credits relevant to contractors through …
Data Collection Algorithm Based On Regression Analysis, Aiming To Minimize Data Processing Delays In 6g-Enabled Iot Networks, Archana Rajendra Mane, Sachin Vasant Chaudhari
Data Collection Algorithm Based On Regression Analysis, Aiming To Minimize Data Processing Delays In 6g-Enabled Iot Networks, Archana Rajendra Mane, Sachin Vasant Chaudhari
Mansoura Engineering Journal
Researchers are currently investigating 6G wireless communication technologies because they can offer ultra-low latency, high data rates, and smarter network management than 5G. IoT services have spurred the development of cutting-edge technologies such as quantum communications, terahertz (THz), and artificial intelligence (AI), all of which are expected to be included into the subsequent generation of 6G networks. This paper presents a regression-based data collection algorithm for 6G-enabled IoT networks that dynamically prioritizes data through Random Forest regression. With a Mean Absolute Error (MAE) of 0.62 ms and a Root Mean Squared Error (RMSE) of 0.83 ms, the proposed method can …
Teleoperated Mobile Robot For Pesticide Spraying And Greenhouse Navigation: Numerical Analysis, Wessam Atwa, Zakaria Ismail, Mohsen Egela, Mohamed G. Alkalla
Teleoperated Mobile Robot For Pesticide Spraying And Greenhouse Navigation: Numerical Analysis, Wessam Atwa, Zakaria Ismail, Mohsen Egela, Mohamed G. Alkalla
Mansoura Engineering Journal
Pesticide spraying in greenhouses is a dangerous process as the operator should wear protective suits and masks against the chemicals, which cause skin and eye irritation, respiratory issues, and even cancer. Other severe conditions involve elevated temperature and humidity in the confined greenhouse atmosphere. Therefore, this article proposes a novel teleoperated mobile robot for pesticide spraying called AMR-BPS to address such issues. It aims to keep the human securely outside during the spraying process. AMR-BPS has a novel design incorporating many innovative mechanisms, such as an extendable spraying boom, independent control of each spraying side, adjustable nozzle angles, and 2D-LiDAR …
Conductive Bitumen And Asphalt Mixtures For Smart Pavements: De-Icing And Snow Melting, Self-Healing, Energy Harvesting, And Self-Sensing Monitoring, Ahmed Fouda, Pengfei Liu, Aboelkasim Diab, Lingyun You, Fan Gu, Xu Yang, Alaa Gabr, Sherif El-Badawy, Ahmed Awed
Conductive Bitumen And Asphalt Mixtures For Smart Pavements: De-Icing And Snow Melting, Self-Healing, Energy Harvesting, And Self-Sensing Monitoring, Ahmed Fouda, Pengfei Liu, Aboelkasim Diab, Lingyun You, Fan Gu, Xu Yang, Alaa Gabr, Sherif El-Badawy, Ahmed Awed
Mansoura Engineering Journal
Evolving transportation infrastructure requires transitioning from passive roadways to smart, multifunctional pavement systems. This review synthesizes research on conductive bitumen and asphalt mixtures engineered for self-heating, self-healing, and self-sensing capabilities. Self-heating enables conductive pavements to generate heat internally via Joule heating or electromagnetic induction, raising surface temperatures for de-icing or healing activation without external heat.
Based on percolation theory, integrating conductive additives from carbon-based fillers (graphite powder, GP; carbon black, CB; graphene) to metallic fibers (steel wool, SW; steel fibers, SFs)—transforms the insulating bituminous matrix into a conductive composite. A key trade-off exists: fibrous additives like carbon fibers (CFs) and …
Experimental Investigation And Optimization Of Process Parameters Affecting The Compressive And Flexural Strength Of Epoxy Concrete For Machine Tool Structure By Using Taguchi Method, Amitkumar C Gohil, Hardik G. Chothani
Experimental Investigation And Optimization Of Process Parameters Affecting The Compressive And Flexural Strength Of Epoxy Concrete For Machine Tool Structure By Using Taguchi Method, Amitkumar C Gohil, Hardik G. Chothani
Mansoura Engineering Journal
The structural performance of machine tool is strongly influenced by rigidity and damping characteristic; however, conventional material such as grey cast iron and steel exhibits limitation in achieving an optimal balance between weight, strength and vibration damping. The necessitates the development of alternative material with improved performance. In this study epoxy concrete is investigated as a potential material for machine tool structure, focusing on its compressive strength and flexural strength. A systematic experimental approach based on Taguchi method (L25 orthogonal array) was employed to optimize key process parameter, including resin contain, aggregate size, sand proportion, shaking time and curing duration. …
Data-Driven Prediction Of Compressive Strength In Pofa-Modified Concrete: A Comparative Study Of Lr, Nlr, And Ann Models, Shuaaib A. Mohammed, Hawdin Ismael Ibrahim, Diar Fatah Abdulrahman Askar, Hersh F Mahmood, Mehdi Khodaei, Soran Abdrahman Ahmad
Data-Driven Prediction Of Compressive Strength In Pofa-Modified Concrete: A Comparative Study Of Lr, Nlr, And Ann Models, Shuaaib A. Mohammed, Hawdin Ismael Ibrahim, Diar Fatah Abdulrahman Askar, Hersh F Mahmood, Mehdi Khodaei, Soran Abdrahman Ahmad
Mansoura Engineering Journal
Production of concrete results in high CO2 emissions, high energy demand, and consumption of various raw materials; however, it is one of the most widely used materials in construction to date. Therefore, researchers aim to minimize the impact of concrete production through various methods, such as introducing sustainable sources of materials that can be used in concrete. For instance, agricultural waste materials can be used as partial cement replacement. This study presents a comprehensive data-driven analysis of the effects of POFA on the properties of normal-strength concrete. By synthesizing a database of 196 experimental datasets from existing literature, three …
Evaluating Matching Frontier Methods For Crash Modification Factor Estimation, Usama Elrawy Shahdah, Eman K . Ali, Sania Reyad Elagamy
Evaluating Matching Frontier Methods For Crash Modification Factor Estimation, Usama Elrawy Shahdah, Eman K . Ali, Sania Reyad Elagamy
Mansoura Engineering Journal
This study evaluates "matching frontier" methods against conventional approaches for estimating Crash Modification Factors (CMFs). Thirty-four method-model combinations were tested, including 16 frontier variants, 8 propensity-score-matching algorithms with negative binomial and mixed-effects models, and two benchmarks (empirical Bayes and cross-sectional), across multiple sample sizes and three true CMF values (0.80, 1.00, and 1.30). Of these, 30 converged successfully; 4 mixed-effects models with replacement-based matching failed due to duplicate control observations. Each scenario was evaluated across 10 Monte Carlo replications to quantify performance uncertainty.
Synthetic crash data were generated with known treatment effects, examining scenarios ranging from ideal (386 treated, 21,000 …
Event-Related Potential Variation In Response Accuracy: A Comparative Analysis Using Mne-Python, Akash Rajak, Sachin Umrao
Event-Related Potential Variation In Response Accuracy: A Comparative Analysis Using Mne-Python, Akash Rajak, Sachin Umrao
Mansoura Engineering Journal
Event-Related Potentials (ERPs) are extensively employed in the examination of neural responses linked with cognitive processing and changes in brain activity. In this work, we conducted a comparative analysis of ERPs on a publicly available EEG dataset (122 subjects, alcoholic and control groups) with the help of the MNE-Python framework. The 64 electrodes for EEG were placed according to the international 10 - 20 system, and EEG was sampled at a 256 Hz sampling rate over 1-second epochs. The preprocessing pipeline consisted of 1 - 40 Hz bandpass filtering, noise reduction, spectral computation, and ERP waveform analysis. Temporal neural activity …
Optimisation Of Stepped Basin Solar Still With Response Surface Methodology And Machine Learning Methods, M. Balamurugan, V. Santhanam, B. Deepanraj, S. P Manikandan, M. Yuvaperiyasamy, N. Senthilkumar
Optimisation Of Stepped Basin Solar Still With Response Surface Methodology And Machine Learning Methods, M. Balamurugan, V. Santhanam, B. Deepanraj, S. P Manikandan, M. Yuvaperiyasamy, N. Senthilkumar
Mansoura Engineering Journal
This research focuses on enhancing the distillate output of a stepped basin solar still by optimizing key operational variables using Response Surface Methodology (RSM) and advanced machine learning techniques. As water scarcity remains a critical global challenge, solar stills offer a viable, sustainable solution for desalination. These systems offer an energy-efficient approach to converting saline water intofreshwater, providing an alternative to conventional desalination methods. The primary objective was to investigate how variations in solar radiation, step height, and water inlet temperature influence the productivity of the stepped basin solar still. The solar radiation ranged from 600 to 1000 W/m², the …
Performance Of Foamed Concrete Before And After Fire Conditions: A Review, Poles Bahgat, Mohamed Kohail, A. Fathy, A. Afifi
Performance Of Foamed Concrete Before And After Fire Conditions: A Review, Poles Bahgat, Mohamed Kohail, A. Fathy, A. Afifi
Mansoura Engineering Journal
Foamed concrete is defined as a type of concrete distinguished by its workability, low density, and insulating properties. It is used as building material. The objective of this review is to discuss the physical and mechanical characteristics and fire sensitivity of foamed concrete. Density influences the strength of concrete. The strength of concrete is between 2 and 3.5 MPa, which increased with the addition of gold mining waste, reaching approximately 35 MPa at optimal replacement levels. There is a 60-70% reduction in strength for lightweight concrete with a density of 400-1200 kg/m³ compared to conventional concrete. The fire sensitivity of …
Remote Sensing-Based Rice Detection: Novel Indices From Optical And Sar Synergy, Kaifi Chomani
Remote Sensing-Based Rice Detection: Novel Indices From Optical And Sar Synergy, Kaifi Chomani
Mansoura Engineering Journal
Accurate rice mapping is challenging due to the lack of a simple, efficient approach and the complexity and limited ability of existing methods to distinguish rice fields from non-rice fields. This study proposes two novel indices: the Multispectral Rice Detection Index (MRDI), which utilises optical imagery, and the OptiRadar Rice Index (ORRI), which incorporates both optical and Synthetic Aperture Radar (SAR) data. Ground-truth data from the Cropland Cropping Systems (CROS) were used to assess the performance of both indices. The findings indicated that MRDI achieved an overall accuracy of 97.97% with perfect recall (100%) but lower precision (78.65%). However, the …
Effect Of Load Variations On Power Quality And Ev Battery Performance In Vehicle-To-Grid System, Jitender Kaushal, Rahul Paswan
Effect Of Load Variations On Power Quality And Ev Battery Performance In Vehicle-To-Grid System, Jitender Kaushal, Rahul Paswan
Mansoura Engineering Journal
Vehicle-to-Grid (V2G) technology enables the exchange of electricity between electric vehicles (EVs) and the utility grid, helping improve the integration of renewable energy sources and the grid's flexibility. Load-dependent power quality disturbances can affect the performance and reliability of V2G systems, which in turn can negatively impact system and battery operation. This study investigates the effect of resistive, inductive and nonlinear loads on the electrical performance and battery behaviour of a bidirectional V2G system. A complete MATLAB/Simulink model was developed to investigate the grid voltage, current, frequency, THD and the battery voltage, current and state of charge. The model uses …
Reconfiguring Environmental Design Thinking: Artificial Intelligence As A Cognitive Partner In Sustainable Architecture – A Novel Hybrid Framework And Empirical Validation Study, Walaa Hussein Hussein Hanafi
Reconfiguring Environmental Design Thinking: Artificial Intelligence As A Cognitive Partner In Sustainable Architecture – A Novel Hybrid Framework And Empirical Validation Study, Walaa Hussein Hussein Hanafi
Mansoura Engineering Journal
This study develops and empirically validates a Hybrid Cognitive Design Framework (HCDF) that integrates artificial intelligence, parametric design, and environmental simulation as a cognitive partnership system for sustainable architectural design. The research addresses a gap in existing studies, which have largely focused on the functional benefits of AI while giving limited attention to its influence on designers’ cognitive and ethical decision-making. A quasi-experimental study was conducted with 30 architecture students divided into two groups: an HCDF-assisted group and a traditional design group. Participants were tasked with designing a self-sufficient residential neighbourhood in Toshka, Egypt. Data were collected using Think-Aloud Protocol …
Analysis Of Gnss Baseline Length Effects On Lidar-Based Uav Topographic Survey Accuracy Using Cors, Ahmed Mostafa, Mohamed El Tokhey, Yasser Mogahed, Tarek Hassan
Analysis Of Gnss Baseline Length Effects On Lidar-Based Uav Topographic Survey Accuracy Using Cors, Ahmed Mostafa, Mohamed El Tokhey, Yasser Mogahed, Tarek Hassan
Mansoura Engineering Journal
The field of land surveying has evolved considerably with the tremendous advancements in the capabilities of Unmanned Aerial Vehicles (UAVs). The integration of Light Detection and Ranging (LiDAR) technology has further enhanced this process by providing an efficient and high-precision solution for topographic surveying. High-precision georeferencing in UAV-LiDAR surveys is constrained by Global Navigation Satellite System (GNSS) baseline length and flight configurations. In remote or operationally restricted areas, where establishing a local GNSS base station is difficult or impossible, Continuously Operating Reference Stations (CORS) represent an alternative solution for ensuring reliable positioning corrections. This study investigates the effect of GNSS …
Comparative Bioassay-Guided Fractionation Of Citrus Species: Phytochemical Characterization And Nanoformulation Of A Polyphenol-Rich Leaf Fraction From Citrus Aurantifolia For Skin Anti-Aging Applications, Noha Swilam, Khaled Nematallah, Amgad Albohy, Noha Badawi, Sameh S. Gad, Maha M. Shouman, Saeed S. Al-Ghamdi, Nahla Ayoub
Comparative Bioassay-Guided Fractionation Of Citrus Species: Phytochemical Characterization And Nanoformulation Of A Polyphenol-Rich Leaf Fraction From Citrus Aurantifolia For Skin Anti-Aging Applications, Noha Swilam, Khaled Nematallah, Amgad Albohy, Noha Badawi, Sameh S. Gad, Maha M. Shouman, Saeed S. Al-Ghamdi, Nahla Ayoub
Pharmacy
Background: Skin aging is driven by oxidative stress and ultraviolet (UV) exposure, leading to extracellular matrix degradation and loss of skin elasticity. This study aimed to identify the most biologically active Citrus species using a bioassay-guided approach and evaluate its potential for dermal applications. Methods: Hydroalcohol extracts and ethyl acetate fractions of Citrus sinensis, Citrus aurantifolia, and Citrus reticulata leaves were screened for antioxidant, enzyme-inhibitory, and polyphenol content. The most active fraction was characterized by UPLC-PDA and LC–MS/MS, formulated into Span-based nanovesicles, and evaluated for physicochemical properties and drug release. Biological activity was assessed using an in vitro scratch wound-healing …
Polyfluoroalkyl Substances And Altered Glucose Homeostasis In Adolescents Following Bariatric Surgery, Elizabeth Costello, Brittney O Baumert, Zhenjiang Li, Vishal Midya, Shudi Pan, Justin R Ryder, Thomas H Inge, Todd M Jenkins, Stephanie Sisley, Stavra A Xanthakos, Anita Courcoulas, Douglas I Walker, Nikos Stratakis, Damaskini Valvi, Scott M Bartell, Angela L Slitt, Rohit Kohli, Sarah Rock, Michele A La Merrill, Sandrah P Eckel, Max T Aung, Rob Mcconnell, David V Conti, Lida Chatzi
Polyfluoroalkyl Substances And Altered Glucose Homeostasis In Adolescents Following Bariatric Surgery, Elizabeth Costello, Brittney O Baumert, Zhenjiang Li, Vishal Midya, Shudi Pan, Justin R Ryder, Thomas H Inge, Todd M Jenkins, Stephanie Sisley, Stavra A Xanthakos, Anita Courcoulas, Douglas I Walker, Nikos Stratakis, Damaskini Valvi, Scott M Bartell, Angela L Slitt, Rohit Kohli, Sarah Rock, Michele A La Merrill, Sandrah P Eckel, Max T Aung, Rob Mcconnell, David V Conti, Lida Chatzi
Children’s Nutrition Research Center Staff Publications
Objectives: Bariatric surgery is an effective treatment for severe obesity and associated metabolic comorbidities. Exposure to polyfluoroalkyl substance (PFAS) before bariatric surgery may attenuate improvements in glucose metabolism and explain some of the heterogeneity in post-surgery outcomes.
Design: This is an observational cohort study.
Methods: Adolescents (n = 186) enrolled in the Teen-Longitudinal Assessment of Bariatric Surgery study were included. Eight-PFAS congeners were measured in plasma before surgery. Linear and logistic regressions were used to examine cross-sectional associations between log2-transformed PFAS (ng/mL) and fasting glucose, insulin, hemoglobin A1c (HbA1c), and homeostatic model assessment for insulin resistance (HOMA-IR). Linear mixed …
Test-Retest Apparent Diffusion Coefficient Reproducibility In Head And Neck Cancer Using A 15-T Mr-Linac, Brigid A Mcdonald, Dina El-Habashy, Renjie He, Sam Mulder, Sarah Mirbahaeddin, Abdallah S R Mohamed, Sara Ahmed, Yao Ding, Jihong Wang, Stephen Y Lai, Alex Dresner, John Christodouleas, Clifton D Fuller
Test-Retest Apparent Diffusion Coefficient Reproducibility In Head And Neck Cancer Using A 15-T Mr-Linac, Brigid A Mcdonald, Dina El-Habashy, Renjie He, Sam Mulder, Sarah Mirbahaeddin, Abdallah S R Mohamed, Sara Ahmed, Yao Ding, Jihong Wang, Stephen Y Lai, Alex Dresner, John Christodouleas, Clifton D Fuller
Faculty, Staff and Student Publications
Purpose
To evaluate the reproducibility of apparent diffusion coefficient (ADC) measurements in head and neck squamous cell carcinoma (HNSCC) using a 1.5-T MR-linac (MRI-guided linear accelerator) system.
Materials and Methods
In this retrospective study, conducted between February 2021 and January 2024, patients with HNSCC lesions underwent echo-planar imaging diffusion-weighted MRI on a 1.5-T MR-linac system at two time points before the start of radiation therapy. Mean and median ADC values and volumes were measured for each lesion. Absolute and percent reproducibility coefficients (RCs) were calculated. Linear regression analyses and F tests were performed to determine whether the lesion volume or …
Spatio-Temporal Responses Of A Migratory Shorebird Community Reflect Complex Trade-Offs Among Overabundance Of Predators And Disturbance, K. M. Aarif, Aymen Nefla, Zuzana Musilova, Petr Musil, Sora M. Estrella
Spatio-Temporal Responses Of A Migratory Shorebird Community Reflect Complex Trade-Offs Among Overabundance Of Predators And Disturbance, K. M. Aarif, Aymen Nefla, Zuzana Musilova, Petr Musil, Sora M. Estrella
Research outputs 2022 to 2026
Animal selection of foraging grounds is a trade-off among available feeding resources, intra and interspecific competition, disturbance and predation risks. The present study was carried out at Kadalundi-Vallikkunnu Community Reserve on the West coast of Kerala (India) in the Central Asian Flyway. The Reserve hosts different coastal habitats, including mudflats, mangroves and sand beaches, and although 31 species of shorebirds are commonly present, it is heavily impacted by human activities. The findings highlight the necessity of robust management of anthropogenic waste and reveal the detrimental impacts of human activities on species communities of conservation concern. We investigated how the densities …
Explainable Convolutional Neural Network Model Provides An Alternative Genome-Wide Association Perspective On Mutations In Sars-Cov-2, Parisa C. Hatami, Richard Annan, Luis Miranda, Jane L. Gorman, Mengjun Xie, Letu Qingge, Hong Qin
Explainable Convolutional Neural Network Model Provides An Alternative Genome-Wide Association Perspective On Mutations In Sars-Cov-2, Parisa C. Hatami, Richard Annan, Luis Miranda, Jane L. Gorman, Mengjun Xie, Letu Qingge, Hong Qin
Computer Science Faculty Publications
Identifying informative genomic features in SARS-CoV-2 can help clarify patterns of viral evolution. In this study, we developed an explainable convolutional neural network (CNN) model to classify SARS-CoV-2 genomic sequences into the WHO-designated Variants of Concern (VOCs), Alpha, Beta, Gamma, Delta, and Omicron. Using a balanced dataset of genomes, the classification CNN achieved 99.96% accuracy on the held-out test set. To interpret the model’s predictions, we applied SHapley Additive exPlanations (SHAP) to estimate the contribution of each nucleotide position to VOC-label prediction and compared aggregated attributions with a chi-square GWAS baseline applied to the same categorical labels. SHAP prioritized several …
Privacy-Preserving Federated Learning With Optimized Ensemble Weighting And Knowledge Distillation For Covid-19 Detection From Non-Iid Medical Imaging Data, Richard Annan, Hong Qin, Robert Newman, Madhuri Siddula, Letu Qingge
Privacy-Preserving Federated Learning With Optimized Ensemble Weighting And Knowledge Distillation For Covid-19 Detection From Non-Iid Medical Imaging Data, Richard Annan, Hong Qin, Robert Newman, Madhuri Siddula, Letu Qingge
Computer Science Faculty Publications
Medical imaging enables rapid and accurate diagnosis of COVID-19, with CT scans proving especially effective. However, data privacy concerns limit collaborative model development across hospitals. To address this issue, we introduce a novel federated learning framework. It is referred to as Independent Knowledge Distillation with post-Ensemble Federated Learning (IKDEFL). Differential Privacy (DP) is integrated into the framework to improve privacy guarantees. Three DP mechanisms are evaluated. These include Fixed Gaussian, Gaussian Adaptive, and Tree Adaptive. The evaluation has been conducted on heterogeneous and Non-Independent and Identically Distributed (Non-IID) datasets. These datasets reflect real-world hospital scenarios. Results show that IKDEFL significantly …
Aquatic Macrophytes As Nature-Based Solutions: Challenges And Opportunities Across Inland And Coastal Waters, Morgan Botrel, Roxane Maranger, Lindsay L. Trottier, Mathieu Cusson, Lars L. Iverson, Fanny Noisette, Christian Nozais, Katrine Turgeon, Andrea Bertolo, Thibaud André-Alphonse, Simon Bélanger, Arthur De Grandpré, Jean-Olivier Goyette, Sabine Hilt, Ladd Johnson, Valérie Langlois, Martin Laporte, Félix Lauzon, Brigitte Légaré, Anne Ola, Marie-Pomme Presne-Poissant, Matthieu Prugne, Caroline Susini, Richard Zimmerman
Aquatic Macrophytes As Nature-Based Solutions: Challenges And Opportunities Across Inland And Coastal Waters, Morgan Botrel, Roxane Maranger, Lindsay L. Trottier, Mathieu Cusson, Lars L. Iverson, Fanny Noisette, Christian Nozais, Katrine Turgeon, Andrea Bertolo, Thibaud André-Alphonse, Simon Bélanger, Arthur De Grandpré, Jean-Olivier Goyette, Sabine Hilt, Ladd Johnson, Valérie Langlois, Martin Laporte, Félix Lauzon, Brigitte Légaré, Anne Ola, Marie-Pomme Presne-Poissant, Matthieu Prugne, Caroline Susini, Richard Zimmerman
OES Faculty Publications
Macrophytes are foundation species whose use as nature-based solution (NbS) in aquatic ecosystems can help reduce climate change impacts while mitigating biodiversity loss. The discrepancy in research and application of macrophytes as NbS across inland and marine coastal ecosystems is an opportunity to expand the concept and learn from different approaches. We report on an initiative uniting marine and freshwater scientists that compared knowledge on macrophytes as NbS across realms, identified advances and gaps in their use, and synthesized challenges and opportunities for application. We conducted a bibliometric analysis and an expert participatory exercise around recent review papers. We reveal …
Patenting Ai Discoveries In Life Sciences: Overcoming Eligibility, Disclosure, And Inventorship Challenges, Dhohyung Kim, Ryan P. Hiler
Patenting Ai Discoveries In Life Sciences: Overcoming Eligibility, Disclosure, And Inventorship Challenges, Dhohyung Kim, Ryan P. Hiler
IP Theory
The pharmaceutical and biotechnology industries face transformative opportunities through artificial intelligence and machine learning integration. However, these technological advances create distinct patent law complications that traditional drug development does not encounter. This article analyzes three interconnected obstacles: establishing eligible subject matter under 35 U.S.C. § 101, meeting disclosure standards under § 112(a), and determining proper inventorship when AI systems contribute substantially to claimed inventions. Drawing from recent USPTO guidance and Federal Circuit precedent, this analysis offers evidence-based strategies for patent practitioners, research scientists, and business leaders seeking robust intellectual property protection for AI-integrated pharmaceutical innovations.