Life Sciences Commons^™

Ai-Enabled Wearable Cameras For Assisting Dietary Assessment In African Populations, Frank P-W Lo, Jianing Qiu, Modou L Jobarteh, Yingnan Sun, Zeyu Wang, Shuo Jiang, Tom Baranowski, Alex K Anderson, Megan A Mccrory, Edward Sazonov, Wenyan Jia, Mingui Sun, Matilda Steiner-Asiedu, Gary Frost, Benny Lo

Children’s Nutrition Research Center Staff Publications

We have developed a population-level method for dietary assessment using low-cost wearable cameras. Our approach, EgoDiet, employs an egocentric vision-based pipeline to learn portion sizes, addressing the shortcomings of traditional self-reported dietary methods. To evaluate the functionality of this method, field studies were conducted in London (Study A) and Ghana (Study B) among populations of Ghanaian and Kenyan origin. In Study A, EgoDiet's estimations were contrasted with dietitians' assessments, revealing a performance with a Mean Absolute Percentage Error (MAPE) of 31.9% for portion size estimation, compared to 40.1% for estimates made by dietitians. We further evaluated our approach in Study …

Ices Roadmap For Marine Recreational Fisheries (Mrf), International Council For The Exploration Of The Sea (Ices), Karina L. Ryan

Fisheries Research Articles

Purpose of the roadmap

The overarching goal of this roadmap is to guide the development of robust marine recreational fisheries (MRF) assessments through data and methodological improvements, in line with current and future management needs. To address the requirements of the policy and legislative instruments in relation to MRF and to plan future steps in ICES, there is need to further improve and operationalize the required MRF dataflows and assessment procedures. Better integration of MRF into advice is in line with ICES vision and mission alongside its advisory framework and principles. This will assist not only managers but also the …

Integrative Multi-Omics Analysis Uncovers Tumor-Immune-Gut Axis Influencing Immunotherapy Outcomes In Ovarian Cancer, Spencer R Rosario, Mark D Long, Shanmuga Chilakapati, Eduardo Cortes Gomez, Sebastiano Battaglia, Prashant K Singh, Jianmin Wang, Katy Wang, Kristopher Attwood, Suzanne M Hess, A J Robert Mcgray, Kunle Odunsi, Brahm H Segal, Gyorgy Paragh, Song Liu, Jennifer A Wargo, Emese Zsiros

Faculty, Staff and Student Publications

Recurrent ovarian cancer patients, especially those resistant to platinum, lack effective curative treatments. To address this, we conducted a phase 2 clinical trial (NCT02853318) combining pembrolizumab with bevacizumab, to increase T cell infiltration into the tumor, and oral cyclophosphamide, to reduce the number of regulatory T cells. The trial accrued 40 heavily pretreated recurrent ovarian cancer patients. The primary endpoint, progression free survival, was extended to a median of 10.2 months. The secondary endpoints demonstrated an objective response rate of 47.5%, and disease control in 30% of patients for over a year while maintaining a good quality of life. We …

Clonal Landscape And Clinical Outcomes Of Telomere Biology Disorders: Somatic Rescue And Cancer Mutations, Fernanda Gutierrez-Rodrigues, Emma M Groarke, Natthakan Thongon, Juan Jose Rodriguez-Sevilla, Luiz Fernando B Catto, Marena R Niewisch, Ruba Shalhoub, Lisa J Mcreynolds, Diego V Clé, Bhavisha A Patel, Xiaoyang Ma, Dalton Hironaka, Flávia S Donaires, Nina Spitofsky, Barbara A Santana, Tsung-Po Lai, Lemlem Alemu, Sachiko Kajigaya, Ivana Darden, Weiyin Zhou, Paul V Browne, Subrata Paul, Justin Lack, David J Young, Courtney D Dinardo, Abraham Aviv, Feiyang Ma, Michel Michels De Oliveira, Ana Paula De Azambuja, Cynthia E Dunbar, Malgorzata Olszewska, Emmanuel Olivier, Eirini P Papapetrou, Neelam Giri, Blanche P Alter, Carmem Bonfim, Colin O Wu, Guillermo Garcia-Manero, Sharon A Savage, Neal S Young, Simona Colla, Rodrigo T Calado

Faculty, Staff and Student Publications

Telomere biology disorders (TBDs), caused by pathogenic germ line variants in telomere-related genes, present with multiorgan disease and a predisposition to cancer. Clonal hematopoiesis (CH) as a marker of cancer development and survival in TBDs is poorly understood. Here, we characterized the clonal landscape of a large cohort of 207 patients with TBD with a broad range of age and phenotype. CH occurred predominantly in symptomatic patients and in signature genes typically associated with cancers: PPM1D, POT1, TERT promoter (TERTp), U2AF1S34, and/or TP53. Chromosome 1q gain (Chr1q+) was the commonest karyotypic abnormality. Clinically, multiorgan involvement and CH in TERTp, TP53, …

Species Detection And Discovery Of Zoanthidea Symbiotic With Deep-Sea Gorgonians, Saige Jost

All HCAS Student Capstones, Theses, and Dissertations

Symbiotic marine invertebrates known as Zoanthidea, from the phylum Cnidaria, live on a wide diversity of other organisms. Deep-sea corals such as Gorgonians are one of these clades of hosts. These octocorals and their Zoanthidean symbionts are challenging to collect and consequently difficult to study. However, the Evolution of Marine Symbioses Laboratory at Nova Southeastern University has obtained several samples from the Yale Peabody Museum and other museums or universities with the goal of expanding our knowledge of the diversity of Zoanthideans. Until recently, the existing taxonomic system has been based on morphological characters. A competing molecular parataxonomic system has …

Targeting The Cholesterol Storage Enzyme Acat1/Soat1 In Brain Cells And Mouse Model: A Novel Approach To Address Aging And Apoe4-Related Neuroinflammation, Thao Nguyen Phuong Huynh Krumeich

Dartmouth College Ph.D Dissertations

Alzheimer’s Disease (AD) is a progressive neurodegenerative disease that significantly impacts nearly 7 million people in the United States. AD is characterized by the deposition of amyloid beta (Ab) plaque, tau neurofibrillary tangles (NFTs), lipids granules, and neuroinflammation. Age and apolipoprotein E4 (APOE4) are the two biggest risk factors for AD. Recent AD therapeutic development has mostly benefited the patient population with milder symptoms while causing serious side effects in APOE4 carriers, leaving the most impacted patients’ group - aged APOE4 carriers with no treatment option. With the increasing aging population, there is an urgent need for a …

Bile Duct Ligation-Induced Cirrhosis Does Not Alter The Blood-Brain Barrier Permeability To Sucrose In Rats, Mohammad K. Miah, Ulrich Bickel, Reza Mehvar

Pharmacy Faculty Articles and Research

Contradictory results have been reported about the effects of liver diseases on the blood-brain barrier (BBB) permeability to markers. For instance, both an increase and no change in the BBB permeability to BBB markers sodium fluorescein and Evans blue have been reported in experimental cholestasis induced by bile duct ligation (BDL) in rats. These contradictory effects might be due to inherent limitations of these markers and/or methodological issues. Here, we investigated the time course of the impact of BDL in rats on BBB permeability using a recently developed stable isotope labeled marker [¹³C]sucrose, which is expected to be …

A Heuristic Evaluation Of A Pharmacy Surveillance Information System, Reza Abbasi, Mehrdad Farzandipour, Habiballah Rahimi, Yang Gong, Ehsan Nabovati

Faculty, Staff and Student Publications

Introduction: The pharmacy surveillance information system (PSIS) is intended to manage the dispensing practice of under-controlled drugs and substances. We designed and developed a PSIS for the first time in a developing country. This study aimed to evaluate the usability of this system using a heuristic evaluation method before the pilot implementation in outpatient pharmacies.

Materials and methods: The study was conducted in 2022 during the development of a pharmacy surveillance information system. Five evaluators examined the system using Nielson's heuristic evaluation method. The detected usability problems were categorized into 10 Nielson's usability principles, and their severity was calculated.

Results: …

Immune Landscape Of Isocitrate Dehydrogenase-Stratified Primary And Recurrent Human Gliomas, Pravesh Gupta, Minghao Dang, Shivangi Oberai, Simona Migliozzi, Rakesh Trivedi, Gayatri Kumar, Mekenzie Peshoff, Nancy Milam, Aml Ahmed, Krishna Bojja, Tuan M Tran, Joy Gumin, Carlos Kamiya-Matsuoka, Jason Huse, Kathryn Cox, Jianzhuo Li, Huma Shehwana, Sameer A Sheth, Rodriguez Saxon, Sun Baohua, Brittany Parker Kerrigan, Atul Maheshwari, Edwin Roger Parra Cuentas, Nicholas E Navin, Amy B Heimberger, Frederick F Lang, Antonio Iavarone, Karen Clise-Dwyer, Linghua Wang, Krishna P Bhat

Faculty, Staff and Student Publications

Background: Human gliomas are classified using isocitrate dehydrogenase (IDH) status as a prognosticator; however, the influence of genetic differences and treatment effects on ensuing immunity remains unclear.

Methods: In this study, we used sequential single-cell transcriptomics on 144 678 and spectral cytometry on over 2 million immune cells encompassing 48 human gliomas to decipher their immune landscape.

Results: We identified 22 distinct immune cell types that contribute to glioma immunity. Specifically, brain-resident microglia (MG) were reduced with a concomitant increase in CD8+ T lymphocytes during glioma recurrence independent of IDH status. In contrast, IDH-wild type-associated patterns, such as an abundance …

Sk609, A Novel Dopamine D3 Receptor Agonist And Norepinephrine Transporter Blocker With Putative Pro-Cognitive Actions, Does Not Induce Psychostimulant-Like Increases In Risky Choice During Probabilistic Discounting, Christopher P. Knapp, Brooke Fallon, Sandhya Kortagere, Barry D. Waterhouse, Stan B Floresco, Rachel L Navarra

Rowan-Virtua School of Osteopathic Medicine Departmental Research

RATIONALE: Psychostimulants, such as amphetamine (AMPH) and methylphenidate (MPH), non-selectively elevate extracellular concentrations of the catecholamine neurotransmitters, dopamine (DA) and norepinephrine (NE), and are common pharmacological strategies used to improve prefrontal cortex (PFC)-dependent cognitive dysfunction. However, this approach can be problematic given AMPH has been shown to increase preference for risky choices in a rodent assay of risk/reward decision making. SK609 is a novel NE reuptake blocker that selectively activates DA D3 receptors without affinity for the DA transporter. SK609 has been shown to improve cognitive performance without increasing psychostimulant-like spontaneous locomotor activity, suggesting SK609 may benefit neurocognitive function without …

Clinical Utility Of Opencap Motion Analysis In Lower Limb Prosthesis Users, Sarahi Fernandez Leon

Honors Program Theses and Research Projects

The use of prosthetics has gradually increased due to various diseases, and it is estimated that 35-40 million people are prosthetic/orthotic users, with the number estimated to increase to two billion by 2050. Mobility has been determined to be a strong predictor of quality of life. There are various ways to measure mobility and predict outcomes in lower-limb amputees (LLA), such as self-report and performance-based measures. However, these come with many limitations, showcasing the need for quantitative measures of gait parameters to allow for better development of prosthetic components. Motion analysis tools are expensive and time consuming, but an inexpensive, …

Place Branding: More Than Just A Logo, Marilyn R. Schlake

Cornhusker Economics

Place branding can distinguish one community from another. In a landscape of locations that provide the same amenities, environments, and opportunities, branding can help a community “stand out.” However, what is usually missing is a place brand developed in association with the community’s history, values, social connections, and organization associations that have evolved.

Consistency And Flexibility Of Character In Free-Ranging Male African Elephants Across Time, Age, And Social Contexts, Caitlin E. O’Connell-Rodwell, Jodie L. Berezin, Colleen Kinzley, Patrick T. Freeman, Monica N. Sandri, Dustin Kieschnick, Timothy C. Rodwell, Mariana Abarca, Virginia Hayssen

Biological Sciences: Faculty Publications

Post-dispersal male African elephants (Loxodonta africana) live within complex social networks. To quantify the consistency of male elephant character (or personality) within these networks, we employed behavioral repeatability analysis tools across social and environmental contexts. We collected behavioral data from thirty-four individually-identified male elephants at the same waterhole over five field seasons (2007–2011) in Etosha National Park, Namibia. Using repeatability models to assess ten behavioral categories, we found five behaviors (affiliation, aggression, dominance, self-directed anxious, and self-directed comfort) were consistent at the individual level. Some of these behaviors were also repeatable, depending on social context. In particular, the …

Chickpea Proteome Analysis Reveals Genotype-Dependent Variations Associated With Seed Traits, Utpal Bose, Sally Buck, Xavier Sirault, Mahya Bahmani, Keren Byrne, Sally Stockwell, Sean Mcwilliam, Michelle Colgrave, Angéla Juhász, Jean Philippe Ral

Research outputs 2022 to 2026

Chickpea (Cicer arietinum L.) is the second most widely grown legume crop after soybean. Here, we measured the macronutrients and performed proteome profiling of eight chickpea cultivars using two complementary protein extraction solvents. The total protein, starch, and soluble sugar contents significantly differ between cultivars, and we quantified 2434 and 1809 proteins, respectively, from urea- and water-based extraction solvents using a data-independent acquisition approach. The proteome-level differences can vary from 9-25% for the urea-extracted proteins, and the storage protein abundances significantly differed between the cultivars, where legumin content was detected as the highest, followed by vicilin and albumin. Fifty common …

Diet And Immune Effects Trial (Diet)- A Randomized, Double-Blinded Dietary Intervention Study In Patients With Melanoma Receiving Immunotherapy, Rachel M Farias, Yan Jiang, Erma J Levy, Cindy Hwang, Jian Wang, Elizabeth M Burton, Lorenzo Cohen, Nadim Ajami, Jennifer A Wargo, Carrie R Daniel, Jennifer L Mcquade

Faculty, Staff and Student Publications

Background: Gut microbiome modulation is a promising strategy for enhancing the response to immune checkpoint blockade (ICB). Fecal microbiota transplant studies have shown positive signals of improved outcomes in both ICB-naïve and refractory melanoma patients; however, this strategy is challenging to scale. Diet is a key determinant of the gut microbiota, and we have previously shown that (a) habitual high dietary fiber intake is associated with an improved response to ICB and (b) fiber manipulation in mice impacts antitumor immunity. We recently demonstrated the feasibility of a controlled high-fiber dietary intervention (HFDI) conducted in melanoma survivors with excellent compliance and …

Trajectory, Interactions, And Predictors Of Higher Symptom Burden During Induction Therapy For Multiple Myeloma, Mona Kamal, Qiuling Shi, Shu-En Shen, Charles Cleeland, Xin Shelley Wang

Faculty, Staff and Student Publications

Background: Patients with multiple myeloma (MM) experience disabling symptoms that are difficult to manage and may persist after induction therapy. Monitoring disease-related and induction therapy-induced symptoms and identifying patients at greater risk for high symptom burden are unmet clinical needs. The objective of this study was to examine the trajectories of symptom severity over time and identify predictors of high symptom burden during MM induction therapy.

Methodology: Eligible patients with MM rated their symptoms by completing the MD Anderson Symptom Inventory MM module repeatedly during 16 weeks of induction therapy. Group-based trajectory modeling identified patient groups with persistently high-severity (versus …

Glutamate Receptors At The Zebrafish Neuromuscular Junction, Trenton Randall

Honors College Theses

Glutamate is the main excitatory neurotransmitter in the CNS, but at the neuromuscular junction, that role is taken by acetylcholine. However, during embryonic development, non-cholinergic receptors, including those for glutamate, are also present at the NMJ, which are not maintained unless used. These receptors can still form functional circuits, as evidenced by a process called neurotransmitter respecification, in which a neuron changes which neurotransmitter it releases, and is accompanied by the upregulation of the corresponding receptor by the muscle. This process has been observed in frogs and in rats. We predict that zebrafish also exhibit this neurotransmitter plasticity. To assess …

The Challenges Of Diet Generalism In A Microbial Predator, Dictyostelium Discoideum, Shreenidhi Perukkaranai Madabhushi

Arts & Sciences Graduate Student Theses and Dissertations

Organisms vary widely in their diet breadth, ranging from specialists that feed on few resources to generalists that feed on many. Specialists have honed their ability to catch and process specific prey, but generalists must deal with prey that differ in nutritional quality and defensive mechanisms. Have generalist predators overcome costs associated with consuming multiple prey species or do they experience costly trade-offs when handling different prey? Generalist predators also live in environments that vary in the type and abundance of prey species. How do generalists navigate this variation in prey abundance and profitability and seek out their preferred prey? …

Trend And Awareness Of E-Cigarettes Among Students In A Private College In Sabah Malaysia, Vitalis Ronald Eden, Hazrina Hamid, Sreemoy Das, Regidor Iii Dioso

AUIQ Complementary Biological System

Objective: This study aims to investigate the trend and awareness of e-cigarette use among students in a private college located in Sabah, Malaysia. Research Methods: The cross-sectional study was conducted in a private college in Sabah. A self-administered questionnaire was adapted and distributed to 300 randomly selected students regardless of their e-cigarettes vaping status. IBM SPSS Statistic 27 was utilized to analysed accumulated data. Results: A-245 students participated in the study with a response rate of 81.6%. Majority of the respondent were female (69.8%), Bumiputera Sabah (72.2%), Diploma students (90%) aged 22-25 years’ old. The study revealed that almost all …

Survey And Comparative Analysis Of Pollinator Diversity, Abundance, And Foraging Activity Of Diptera And Hymenoptera In Selected Habitats Of South Texas, Melissa Villarreal

Theses and Dissertations

With the declining bee population, non-bee pollinators can serve as an alternative source for pollination. Diptera is a potential source of untapped pollinator resources based on their abundance and visitation rate, but they are understudied in the field of pollination ecology. This study aimed to characterize the pollinator community in selected areas of South Texas. It focused on the Diptera and Hymenoptera families to compare their diversity, relative abundance, foraging behaviors, environmental influences, and vegetation associations. Active sampling and line transect were used in the survey to sample the Hymenoptera and Diptera communities to their family taxonomic rank. Statistical analyses …

The Influence Of Wind Energy Development On Occupancy Of Medium And Large-Sized Mammals In South Texas, Elwynn Sherman

Theses and Dissertations

Conservation paradigms have shifted from single to multi-species approaches for assessing and conserving mammalian populations and the habitats that they occupy. The effect of wind turbine development is an important anthropogenic change to study due to the increasing demand for wind energy in Texas. In this study, I gathered remote camera trap data on medium and large-sized mammal populations in south Texas Tamaulipan thornscrub habitat. The objectives were to determine species presence, the effect of habitat characteristics and anthropogenic disturbances on species occupancy, and the effect of temperature on species detection. The results showed that distance from wind turbines did …

Correlation Between Maximal Eccentric And Isometric Multi-Joint Lower-Extremity Strength And Vertical Jumping Performance In Young Adults, Joonsun Park, Cassidy Weeks, Brennan J. Thompson, Talin Louder

Kinesiology and Health Science Student Research

Maximal eccentric (MES) and isometric (MIS) muscle strength may enhance vertical jump performance by facilitating preloading and reducing energy loss during the eccentric (ECC) phase of the stretch-shortening cycle (SSC). However, the contributions of ECC and isometric (ISO) strength to the countermovement (CMJ) and depth jump (DJ) remain unclear due to variability in assessment methods (e.g., dynamometry, isometric mid-thigh pull) and the limited range of metrics examined in prior research. The aim of this study was to assess correlations between multi-joint lower extremity MES and MIS, obtained using a seated multi-joint isokinetic dynamometer, and 13 vertical ground reaction force (GRF) …

Roquea, A New Genus Of Lychnophorinae (Vernonieae, Asteraceae) From Brazil And Its Phylogenetic Placement, Benoit Loeuille, Roberto Baptista Pereira Almeida, Carolina Moriani Siniscalchi, Makeli G. Lusa, Guilherme Medeiros Antar

UL Publications

Lychnophorinae (Vernonieae, Asteraceae) consists of 21 genera and approximately 150 species, primarily distributed in the Brazilian Central Plateau, with several novelties recently described. With new botanical expeditions conducted in Serra da Formosa, state of Minas Gerais, a set of collections that belong to Lychnophorinae but were not easily assigned to a genus was discovered. After morphological and anatomical analyses and phylogenetic studies, we describe and illustrate Roquea, a new genus of Asteraceae from Brazil, to accommodate the new species Roquea multiserialis. Affinities of the new genus with other genera of Lychnophorinae are discussed along with a preliminary conservation …

An In-Depth Investigation Into Yersinia Pestis Phages: Isolating A Yersinia Pestis Phage From Soil And Constructing A Comprehensive Phylogenetic Analysis Of Known Yersinia Pestis Phages, Jacqueline Chavez

All HCAS Student Capstones, Theses, and Dissertations

Yersinia pestis, the causative agent of the plague, has become increasingly resistant to many antibiotics; therefore, alternatives such as phage therapy are necessary. Phage therapy uses combinations of bacteriophages or phages, which are viruses that only infect bacteria. However, phages—especially Y. pestis phages —are severely understudied. Thus, this research has sought to specifically isolate a phage from soil that infects Y. pestis. There were 146 samples that were collected from across the US, focusing on those with reported cases of plague. These samples were enriched with Y. pestis to maximize the amount of potential phage that target Y. pestis. …

Red Grouper (Epinephelus Morio) Neurocranium, David Ferreiro

All Scans: Kerstetter Fisheries and Avian Ecology 3D Scan Series

No abstract provided.

Jack O’Lantern Pumpkin Response To Carfentrazone, Glufosinate, And Glyphosate Applied To The Distal Portion Of The Vine, Stephen L. Meyers, Celia Corado, Jeanine Arana Cordonero, Carlos Lopez, Lidysce Mata, Emmanuel G. Cooper, Josue Cerrito

Department of Horticulture & Landscape Architecture Faculty Publications

Chemical weed control in pumpkin (Cucurbita pepo) often relies on herbicide applications made at planting, which results in weed escapes later in the growing season. The use of postemergence herbicides in row middles is useful, especially in no-till pumpkin production, but there are limited effective options. We conducted field research in 2023 at Wanatah and Lafayette, IN, USA, to evaluate ‘Bayhorse Gold’ pumpkin response to carfentrazone, glufosinate, and glyphosate applied to 10% of the vine tip 5 weeks after planting. A non-treated control was included for comparison. Pooled across both locations at 1, 2, and 4 weeks after …

Differential Infiltration Of Key Immune T-Cell Populations Across Malignancies Varying By Immunogenic Potential And The Likelihood Of Response To Immunotherapy., Islam Eljilany, Sam Coleman, Aik Choon Tan, Martin D. Mccarter, John Carpten, Howard Colman, Abdul Rafeh Naqash, Igor Puzanov, Susanne Arnold, Michelle L. Churchman, Daniel Spakowicz, Bodour Salhia, Julian Marin, Shridar Ganesan, Aakrosh Ratan, Craig Shriver, Patrick Hwu, William S. Dalton, George J. Weiner, Jose R. Conejo-Garcia, Paulo Rodriguez, Ahmad A. Tarhini

Markey Cancer Center Faculty Publications

Background: Solid tumors vary by the immunogenic potential of the tumor microenvironment (TME) and the likelihood of response to immunotherapy. The emerging literature has identified key immune cell populations that significantly impact immune activation or suppression within the TME. This study investigated candidate T-cell populations and their differential infiltration within different tumor types as estimated from mRNA co-expression levels of the corresponding cellular markers.

Methods: We analyzed the mRNA co-expression levels of cellular biomarkers that define stem-like tumor-infiltrating lymphocytes (TILs), tissue-resident memory T-cells (TRM), early dysfunctional T-cells, late dysfunctional T-cells, activated-potentially anti-tumor (APA) T-cells and Butyrophilin 3A (BTN3A) isoforms, utilizing …

Epigenetic Modifiers: Exploring The Roles Of Histone Methyltransferases And Demethylases In Cancer And Neurodegeneration, Lauren Reed, Janak Abraham, Shay Patel, Shilpa S Dhar

Faculty, Staff and Student Publications

Histone methyltransferases (HMTs) and histone demethylases (HDMs) are critical enzymes that regulate chromatin dynamics and gene expression through the addition and removal of methyl groups on histone proteins. HMTs, such as PRC2 and SETD2, are involved in the trimethylation of histone H3 at lysine 27 and lysine 36, influencing gene silencing and activation. Dysregulation of these enzymes often leads to abnormal gene expression and contributes to tumorigenesis. In contrast, HDMs including KDM7A and KDM2A reverse these methylation marks, and their dysfunction can drive disease progression. In cancer, the aberrant activity of specific HMTs and HDMs can lead to the silencing …

Breaking The Yoke: A Systematic Unmasking Of Challenges To Sustainable Rural Development In South Sudan, Gai Chol Paul

Journal of Sustainable Social Impact

South Sudan, a young nation grappling with the legacy of protracted conflict, faces significant challenges in fostering sustainable rural development. While the immense potential of its vast agricultural lands remains largely untapped, the persistent triple threat of insecurity, deficient infrastructure, and the absence of robust government policy actively hinders progress. The ongoing armed conflict, characterized by inter-communal violence and sporadic attacks, casts a long shadow over rural areas in South Sudan. Thus, I developed this mixed-method multiple-case study, grounded in the sustainable livelihoods framework, to explore challenges that hinder sustainable rural development in South Sudan. I collected data through document …

Correction: Nepali Oral Microbiomes Reflect A Gradient Of Lifestyles From Traditional To Industrialized, Erica P Ryu, Yoshina Gautam, Diana M Proctor, Dinesh Bhandari, Sarmila Tandukar, Meera Gupta, Guru Prasad Gautam, David A Relman, Ahmed A Shibl, Jeevan Bahadur Sherchand, Aashish R Jha, Emily R Davenport

Faculty, Staff and Student Publications

No abstract provided.