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Articles 241 - 270 of 6458
Full-Text Articles in Life Sciences
Investigations On Rangeland Grasshoppers: Ecoregion Level Distribution, Identification, Feeding Performance, And Vegetation Clipping, Muhammad Ullah
Investigations On Rangeland Grasshoppers: Ecoregion Level Distribution, Identification, Feeding Performance, And Vegetation Clipping, Muhammad Ullah
Department of Entomology: Dissertations, Theses, and Student Research
Short-horned grasshoppers (Orthoptera: Acrididae) were studied in the field as well as in laboratory for their distribution, identification, preferred food plants and feeding damage. These grasshoppers are important potential pests of rangelands where they compete for forage with cattle. Examination of the 20 most common grasshoppers by levels 3 and 4 of Nebraska ecoregions revealed specific habitat use and may be helpful in predicting hotspots. The relative abundance of all species analyzed showed at least some significant differences at ecoregion level 4 and two species showed single ecoregion that differed from all others at level 3.
Grasshoppers belonging to subfamilies …
Interactions Of Zooplankton And Phytoplankton With Cyanobacteria, Rebecca Alexander
Interactions Of Zooplankton And Phytoplankton With Cyanobacteria, Rebecca Alexander
School of Natural Resources: Dissertations, Theses, and Student Research
Cyanobacteria are a major concern in Nebraska reservoirs and are capable of producing toxins that can cause skin irritations and gastrointestinal problems, as well as affect the nervous system. It is important to determine the mechanisms that can cause cyanobacteria blooms due to the effect they can have on human health. The interaction of zooplankton and other phytoplankton groups with cyanobacteria is important because there is a biological component in surface waters that should be taken into consideration along with the physical and chemical parameters that have been noted to promote cyanobacteria. For example, zooplankton have the ability to alter …
Population Characteristics, Development Of A Predictive Population Viability Model, And Catch Dynamics For Pallid Sturgeon In The Lower Missouri River, Kirk D. Steffensen
Population Characteristics, Development Of A Predictive Population Viability Model, And Catch Dynamics For Pallid Sturgeon In The Lower Missouri River, Kirk D. Steffensen
School of Natural Resources: Dissertations, Theses, and Student Research
Population characteristics and long-term population trends of pallid sturgeon Scaphirhynchus albus in the lower Missouri River are relatively unknown. As recovery efforts continue, understanding and quantifying these characteristics and trends are critical for species recovery and future management decisions. Therefore, the objectives of this study were to determine the pallid sturgeon population characteristics, predict changes to the pallid sturgeon population based on different management and life history scenarios, and examine trot line catch dynamics in the lower Missouri River. Catch rates for pallid sturgeon collected with gill nets did not significantly change while catch rates using trot lines significantly declined …
The Role Of Hsc-70 In Very Low Density Lipoprotein Tranport Vesicle Golgi Fusion Complex Formation, Erika Nafi Valencia
The Role Of Hsc-70 In Very Low Density Lipoprotein Tranport Vesicle Golgi Fusion Complex Formation, Erika Nafi Valencia
HIM 1990-2015
Excess production and secretion of very low-density lipoprotein (VLDL) by the liver into the circulatory system is directly related to atherosclerosis, a chronic cardiovascular disease that threatens the lives of many worldwide and continues to be a leading cause of death in the United States. The rate-limiting step in VLDL secretion is its transport from the site of biogenesis, the hepatic endoplasmic reticulum to the cis-Golgi. This step is mediated by a specialized ER- derived vesicle, the VLDL transport vesicle (VTV). Upon exit of the ER the VTV targets, fuses and delivers VLDL into the lumen of the Golgi. The …
Morphological Description Of Telaepolella Tubasferens N. G. N. Sp., Isolate Atcc©50593™, A Filose Amoeba In The Gracilipodida, Amoebozoa, Daniel J.G. Lahr, Gabriela M. Kubik, Anastasia L. Gant, Jessica Grant, O. Roger Anderson, Laura A. Katz
Morphological Description Of Telaepolella Tubasferens N. G. N. Sp., Isolate Atcc©50593™, A Filose Amoeba In The Gracilipodida, Amoebozoa, Daniel J.G. Lahr, Gabriela M. Kubik, Anastasia L. Gant, Jessica Grant, O. Roger Anderson, Laura A. Katz
Biological Sciences: Faculty Publications
We describe the amoeboid isolate ATCC©50593™ as a new taxon, Telaepolella tubasferens n. g. n. sp. This multinucleated amoeba has filose pseudopods and is superficially similar to members of the vampyrellids (Rhizaria) such as Arachnula impatiens Cienkowski, 1876, which was the original identification upon deposition. However, previous multigene analyses place this taxon within the Gracilipodida Lahr and Katz 2011 in the Amoebozoa. Here, we document the morphology of this organism at multiple life history stages and provide data underlying the description as a new taxon. We demonstrate that T. tubasferens is distinct from Arachnula and other rhizarians (Theratromyxa, Leptophrys) in …
Restoration Of Biological Soil Crust On Disturbed Gypsiferous Soils In Lake Mead National Recreation Area, Eastern Mojave Desert, Lindsay P. Chiquoine
Restoration Of Biological Soil Crust On Disturbed Gypsiferous Soils In Lake Mead National Recreation Area, Eastern Mojave Desert, Lindsay P. Chiquoine
UNLV Theses, Dissertations, Professional Papers, and Capstones
Biological soil crusts (BSCs) are sensitive to anthropogenic disturbances. Natural recovery takes many years. Active restoration decreases recovery time. Native BSC inocula, which included lichens and mosses, salvaged from gypsiferous soil habitats in Lake Mead National Recreation Area (LMNRA) in the eastern Mojave Desert were stored dry for two years and applied to disturbed soil after a road reconstruction in LMNRA and also used in laboratory experiments to test inoculation technique effectiveness. After 18 months, field results revealed positive relationships between inoculation and the presence of macroscopic BSC cover, cyanobacteria abundance, soil stability, and ammonium concentrations. Chlorophyll fluorescence monitoring of …
The Abundance And Distribution Pattern Of Quagga Mussels In The Las Vegas Bay Of Lake Mead, Nevada And Potential Correlation With Environmental Parameters, Scott Rainville
UNLV Theses, Dissertations, Professional Papers, and Capstones
The non-native quagga mussel [Dreissena bugensis (Andrusov, 1897)] was initially discovered in Boulder Basin of Lake Mead, Nevada-Arizona on January 6, 2007. This occurrence marked the first biological invasion of dreissenid mussels in the Western U.S., following a significant North American range expansion of invasive quagga mussels from populations that invaded and colonized the Great Lakes Region in the Northeastern U.S. during 1991. This nonindigenous mollusk species quickly spread from Boulder Basin and became established throughout the entire reservoir by the end of 2007, with the exception of the inner Las Vegas Bay. There was an apparent absence of settled …
The Update, December 2012, University Of Northern Iowa. College Of Humanities, Arts And Sciences.
The Update, December 2012, University Of Northern Iowa. College Of Humanities, Arts And Sciences.
Update
Inside this issue:
-- Having a Field Day: UNI Students Attend Geology Camp in Wyoming
--Contents December 2012
-- Department News
-- Art Students Present Research Papers at Midwest Humanities Conference
-- School of Music Events
-- Challenging Bullying Through Art
-- Alumni Spotlight: James Arns: Physics
-- UNI Forensics Team
Effects Of Silvicultural Management On Coast Redwood Forest Composition, Density And Structure In Santa Cruz And San Mateo Counties, Michael J. Papa
Effects Of Silvicultural Management On Coast Redwood Forest Composition, Density And Structure In Santa Cruz And San Mateo Counties, Michael J. Papa
Master's Theses
The multiple-objective exploratory study investigates effects of various silvicultural management regimes commonly applied to coast redwood (Sequoia sempervirens [D. Don] Endl.) forests in Santa Cruz and San Mateo Counties, California, USA. A temporary forest inventory was installed in 24 harvest origin stands and 4 natural origin stands throughout the study area (sample area = 1189 acres). Data from the systematic sample of 233 one-quarter acre nested cluster plots (sample intensity = 4.9%) rendered overall forest descriptions in terms of species composition, density, and structure. The common forestry measures of trees per acre (TPA), basal area per acre (BA), and …
Spatial And Temporal Trends Of Freshwater Mussel Assemblages In The Meramec River Basin, Missouri, Usa, J. E. Hinck, Stephen E. Mcmurray, Andrew D. Roberts, M. Christopher Barnhart, Christopher G. Ingersoll, Ning Wang, Tom Augspurger
Spatial And Temporal Trends Of Freshwater Mussel Assemblages In The Meramec River Basin, Missouri, Usa, J. E. Hinck, Stephen E. Mcmurray, Andrew D. Roberts, M. Christopher Barnhart, Christopher G. Ingersoll, Ning Wang, Tom Augspurger
College of Natural and Applied Sciences
The Meramec River basin in east-central Missouri has one of the most diverse unionoid mussel faunas in the central United States with .40 species identified. Data were analyzed from historical surveys to test whether diversity and abundance of mussels in the Meramec River basin (Big, Bourbeuse, and Meramec rivers, representing .400 river miles) decreased between 1978 and 1997. We found that over 20 y, species richness and diversity decreased significantly in the Bourbeuse and Meramec rivers but not in the Big River. Most species were found at fewer sites and in lower numbers in 1997 than in 1978. Federally endangered …
Mir-786 Regulation Of A Fatty-Acid Elongase Contributes To Rhythmic Calcium-Wave Initiation In C. Elegans, Benedict J. Kemp, Erik Allman, Lois Immerman, Megan Mohnen, Maureen A. Peters, Keith Nerhke, Allison L. Abbott
Mir-786 Regulation Of A Fatty-Acid Elongase Contributes To Rhythmic Calcium-Wave Initiation In C. Elegans, Benedict J. Kemp, Erik Allman, Lois Immerman, Megan Mohnen, Maureen A. Peters, Keith Nerhke, Allison L. Abbott
Biological Sciences Faculty Research and Publications
Background: Rhythmic behaviors are ubiquitous phenomena in animals. In C. elegans, defecation is an ultradian rhythmic behavior: every ∼50 s a calcium wave initiating in the posterior intestinal cells triggers the defecation motor program that comprises three sequential muscle contractions. Oscillatory calcium signaling is central to the periodicity of defecation. The posteriormost intestinal cells function as the pacemaker for this rhythmic behavior, although it is unclear how the supremacy of these cells for calcium-wave initiation is controlled.
Results: We describe how the loss of the mir-240/786 microRNA cluster, which results in arrhythmic defecation, causes ectopic intestinal calcium-wave initiation. mir-240/786 expression …
Acute Exercise And Its Effect On Cognitive Performance In Sleep Deprived Individuals: A Review Of Literature., Jennifer Nicole Miller
Acute Exercise And Its Effect On Cognitive Performance In Sleep Deprived Individuals: A Review Of Literature., Jennifer Nicole Miller
Undergraduate Honors Theses
This literature review observes seven different studies that researched the effects of exercise on some measure of cognitive or psychological performance when sleep deprived. The purpose of this review is to consolidate the results of various exercise protocols on the effects of sleep deprivation to make a general conclusion regarding the effect on cognition. This will give insight into the future of research regarding how exercise may combat performance decrements seen when sleep deprived. There are several inconsistencies among current research concerning exercise and sleep deprivation; a standard needs to be created so the results of these studies can be …
Effects Of A Chronic Increase In Plasma Corticosterone On The Brooding Behavior Of The Prairie Skink, Plestiodon Septentrionalis , Alexander James Anton
Effects Of A Chronic Increase In Plasma Corticosterone On The Brooding Behavior Of The Prairie Skink, Plestiodon Septentrionalis , Alexander James Anton
Student Work
The effects of chronic corticosterone (CORT) increases on the maternal behavior of the Prairie Skink, Plestiodon septentrionalis were studied in the laboratory during the summer of 2012. It was hypothesized that chronic increases in plasma CORT would result in decreased maternal effort and higher egg mortality, with similar results to analogous studies in birds. Plasma CORT was elevated using a non-invasive, exogenous treatment and behaviors were observed using video recordings. CORT treatments significantly reduced the amount of time spent tightly coiled around eggs in experimental individuals, and significantly decreased the amount of time experimental females spend in contact with their …
Identifying And Characterizing Non-Coding Rnas In The Dinoflagellate Karenia Brevis, Helen Namataka
Identifying And Characterizing Non-Coding Rnas In The Dinoflagellate Karenia Brevis, Helen Namataka
Master's Theses
When algal cells proliferate and accumulate in marine and fresh water systems, they form algal blo'oms. The majority of these blooms are beneficial, but a significant number are detrimental and are known as harmful algal blooms (HABs). A number of negative effects, including closing of recreational beaches and economic loss, are observed during HABs. Predictably, the longer a bloom persists, the greater its effects on human, environmental and economic health. Karenia brevis, a mixotrophic dinoflagellate, forms HABs, and blooms caused by this organism have been known to remain several months after formation. For these reasons, research has been conducted to …
Fungal Biofilm Colonization And Succession On Artificial Reefs In The North-Central Gulf Of Mexico, Amy Leigh Salamone
Fungal Biofilm Colonization And Succession On Artificial Reefs In The North-Central Gulf Of Mexico, Amy Leigh Salamone
Master's Theses
This study represents the first characterization of natural mixed-species fungal biofilm communities on artificial reefs in the marine environment. Previous fungal biofilm studies have failed to observe the naturally-occurring biodiversity in coastal areas, which comprise the most utilized zone of the marine environment. Artificial reefs can increase fishing yields, amplify oyster habitats, contribute to shoreline stabilization, promote good water quality, and deter pollution. Proper management practices of artificial reefs require knowledge of the colonization of these new habitats by marine organisms and their subsequent succession. Fungi, along with bacteria, archaea, protists, algae, and diatoms, quickly form a complex biofilm on …
Differential Responses To Endothelial–Dependent Relaxation Of The Thoracic And Abdominal Aorta From Male Sprague-Dawley Rats, Ahmed Kolade Oloyo, Simiat Elias, Olusoga Adekunle Sofola
Differential Responses To Endothelial–Dependent Relaxation Of The Thoracic And Abdominal Aorta From Male Sprague-Dawley Rats, Ahmed Kolade Oloyo, Simiat Elias, Olusoga Adekunle Sofola
Biomedical Sciences, East Africa
Regional heterogeneity exists in reactivity of different vascular beds to vasoactive substances. Experiments were designed to determine if there are differences between thoracic and abdominal aorta response to acetylcholineinduced relaxation. Ten male Sprague-Dawley rats with a weighing between 200g–250g were used. The aorta was isolated and 3mm aortic rings were cut and suspended in organ baths containing physiological salt saline (PSS). Contractile and relaxation responses to noradrenaline (NA) and ACh, in the presence or absence of L-NNA and high K+ concentration were studied. Contractile response to NA was similar along the aorta. At the higher doses, ACh elicited a greater …
The Role Of Gene Duplication And Unconstrained Selective Pressures In The Melanopsin Gene Family Evolution And Vertebrate Circadian Rhythm Regulation, Rui Borges, Warren E. Johnson, Stephen J. O'Brien, Vitor Vasconcelos, Agostinho Antunes
The Role Of Gene Duplication And Unconstrained Selective Pressures In The Melanopsin Gene Family Evolution And Vertebrate Circadian Rhythm Regulation, Rui Borges, Warren E. Johnson, Stephen J. O'Brien, Vitor Vasconcelos, Agostinho Antunes
Biology Faculty Articles
Melanopsin is a photosensitive cell protein involved in regulating circadian rhythms and other non-visual responses to light. The melanopsin gene family is represented by two paralogs,OPN4x and OPN4m, which originated through gene duplication early in the emergence of vertebrates. Here we studied the melanopsin gene family using an integrated gene/protein evolutionary approach, which revealed that the rhabdomeric urbilaterian ancestor had the same amino acid patterns (DRY motif and the Y and E conterions) as extant vertebrate species, suggesting that the mechanism for light detection and regulation is similar to rhabdomeric rhodopsins. Both OPN4m and OPN4x paralogs are found …
Peroxiredoxin Ii Regulates Effector And Secondary Memory Cd8+ T Cell Responses, Ryan D. Michalek, Katie E. Crump, Ashley E. Weant, Elizabeth M. Hiltbold, Daniel G. Juneau, Eun-Yi Moon, Dae-Yeul Yu, Leslie B. Poole, Jason M. Grayson
Peroxiredoxin Ii Regulates Effector And Secondary Memory Cd8+ T Cell Responses, Ryan D. Michalek, Katie E. Crump, Ashley E. Weant, Elizabeth M. Hiltbold, Daniel G. Juneau, Eun-Yi Moon, Dae-Yeul Yu, Leslie B. Poole, Jason M. Grayson
Biology Faculty Articles
Reactive oxygen intermediates (ROI) generated in response to receptor stimulation play an important role in cellular responses. However, the effect of increased H2O2on an antigen-specific CD8+ T cell response was unknown. Following T cell receptor (TCR) stimulation, the expression and oxidation of peroxiredoxin II (PrdxII), a critical antioxidant enzyme, increased in CD8+ T cells. Deletion of PrdxII increased ROI, S phase entry, division, and death during in vitro division. During primary acute viral and bacterial infection, the number of effector CD8+ T cells in PrdxII-deficient mice was increased, while the number of memory …
How The Leopard Hides Its Spots: Asip Mutations And Melanism In Wild Cats, Alexsandra Schneider, Victor A. David, Warren E. Johnson, Stephen J. O'Brien, Gregory S. Barsh, Marilyn Menotti-Raymond, Eduardo Eizirik
How The Leopard Hides Its Spots: Asip Mutations And Melanism In Wild Cats, Alexsandra Schneider, Victor A. David, Warren E. Johnson, Stephen J. O'Brien, Gregory S. Barsh, Marilyn Menotti-Raymond, Eduardo Eizirik
Biology Faculty Articles
The occurrence of melanism (darkening of the background coloration) is documented in 13 felid species, in some cases reaching high frequencies at the population level. Recent analyses have indicated that it arose multiple times in the Felidae, with three different species exhibiting unique mutations associated with this trait. The causative mutations in the remaining species have so far not been identified, precluding a broader assessment of the evolutionary dynamics of melanism in the Felidae. Among these, the leopard (Panthera pardus) is a particularly important target for research, given the iconic status of the ‘black panther’ and the extremely …
Functional Analysis Of Drosophila Integrator Complex In Snrna 3' End Processing, Jiandong Chen
Functional Analysis Of Drosophila Integrator Complex In Snrna 3' End Processing, Jiandong Chen
Dissertations and Theses (Open Access)
Uridine-rich small nuclear RNAs (U snRNAs) play essential roles in eukaryotic gene expression by facilitating the removal of introns from mRNA precursors and the processing of the replication-dependent histone pre-mRNAs. Formation of the 3’ end of these snRNAs is carried out by a poorly characterized, twelve-membered protein complex named Integrator Complex.
In the effort to understand Integrator Complex function in the formation of the snRNA 3’ end, we performed a functional RNAi screen in Drosophila S2 cells to identify protein factors required for snRNA 3’ end formation. This screen was conducted by using a fluorescence-based reporter that elicits GFP expression …
Over The Camel's Hump, Brett Kingsley
Over The Camel's Hump, Brett Kingsley
The Synapse: Intercollegiate science magazine
No abstract provided.
Intraspecific Density Dependence And A Guild Of Consumers Coexisting On One Resource, Mark A. Mcpeek
Intraspecific Density Dependence And A Guild Of Consumers Coexisting On One Resource, Mark A. Mcpeek
Dartmouth Scholarship
The importance of negative intraspecific density dependence to promoting species coexistence in a community is well accepted. However, such mechanisms are typically omitted from more explicit models of community dynamics. Here I analyze a variation of the Rosenzweig-MacArthur consumer–resource model that includes negative intraspecific density dependence for consumers to explore its effect on the coexistence of multiple consumers feeding on a single resource. This analysis demonstrates that a guild of multiple consumers can easily coexist on a single resource if each limits its own abundance to some degree, and stronger intraspecific density dependence permits a wider variety of consumers to …
The Influence Of Market Proximity On National Forest Hazardous Fuels Treatments, Max Nielsen-Pincus, Susan Charnley, Cassandra Moseley
The Influence Of Market Proximity On National Forest Hazardous Fuels Treatments, Max Nielsen-Pincus, Susan Charnley, Cassandra Moseley
Environmental Science and Management Faculty Publications and Presentations
The US Department of Agriculture Forest Service's focus on hazardous fuels reduction has increased since the adoption of the National Fire Plan in 2001. However, appropriations for hazardous fuels reduction still lag behind wildfire suppression spending. Offsetting fuels treatment costs through biomass utilization or by using innovative administrative mechanisms such as stewardship contracting are two approaches to stretching appropriated dollars further across the landscape. We use fuels treatment data (n = 8,451 locations) to ask how wood- processing infrastructure influences where and how much hazardous fuels treatments, biomass utilization, and stewardship contracting occur on national forests in Oregon and Washington. …
Long-Term Integrated Studies Show Complex And Surprising Effects Of Climate Change In The Northern Hardwood Forest, Peter M. Groffman, Lindsay E. Rustad, Pamela H. Templer, John L. Campbell, Lynn M. Christenson, Nina K. Lany, Anne M. Socci, Matthew A. Vadeboncoeur, Paul G. Schaberg, Geoffrey W. Wilson, Charles T. Driscoll, Timothy J. Fahey, Melany C. Fisk, Christine L. Goodale, Mark B. Green, Steven P. Hamburg, Chris E. Johnson, Mryon J. Mitchell, Jennifer L. Morse, Linda H. Pardo, Nicholas L. Rodenhouse
Long-Term Integrated Studies Show Complex And Surprising Effects Of Climate Change In The Northern Hardwood Forest, Peter M. Groffman, Lindsay E. Rustad, Pamela H. Templer, John L. Campbell, Lynn M. Christenson, Nina K. Lany, Anne M. Socci, Matthew A. Vadeboncoeur, Paul G. Schaberg, Geoffrey W. Wilson, Charles T. Driscoll, Timothy J. Fahey, Melany C. Fisk, Christine L. Goodale, Mark B. Green, Steven P. Hamburg, Chris E. Johnson, Mryon J. Mitchell, Jennifer L. Morse, Linda H. Pardo, Nicholas L. Rodenhouse
Environmental Science and Management Faculty Publications and Presentations
Evaluations of the local effects of global change are often confounded by the interactions of natural and anthropogenic factors that overshadow the effects of climate changes on ecosystems. Long-term watershed and natural elevation gradient studies at the Hubbard Brook Experimental Forest and in the surrounding region show surprising results demonstrating the effects of climate change on hydrologic variables (e.g., evapotranspiration, streamflow, soil moisture); the importance of changes in phenology on water, carbon, and nitrogen fluxes during critical seasonal transition periods; winter climate change effects on plant and animal community composition and ecosystem services; and the effects of anthropogenic disturbances and …
Chapter 11: Genome-Wide Association Studies, William S. Bush, Jason H. Moore
Chapter 11: Genome-Wide Association Studies, William S. Bush, Jason H. Moore
Dartmouth Scholarship
Genome-wide association studies (GWAS) have evolved over the last ten years into a powerful tool for investigating the genetic architecture of human disease. In this work, we review the key concepts underlying GWAS, including the architecture of common diseases, the structure of common human genetic variation, technologies for capturing genetic information, study designs, and the statistical methods used for data analysis. We also look forward to the future beyond GWAS.
Effects Of Grazing Vs. Resting On Soil Chemistry And Plant Community Dynamics For The Central Coast Of California In 2012, Jessica Combs
Effects Of Grazing Vs. Resting On Soil Chemistry And Plant Community Dynamics For The Central Coast Of California In 2012, Jessica Combs
Animal Science
No abstract provided.
The Effects Of Social And Environmental Enrichments On Leg Strength And Welfare Of Tom Turkeys, Patricia A. Weber
The Effects Of Social And Environmental Enrichments On Leg Strength And Welfare Of Tom Turkeys, Patricia A. Weber
Department of Animal Science: Dissertations, Theses, and Student Research
Two trials (T1, T2) were conducted to determine the effects of enrichment: A) broiler chick addition on early mortality and B) providing environmental enrichments on leg strength and welfare of tom turkeys. Trial 1A utilized 248 1d poults and 8 3d broiler chicks. Four pens of 32 poults were placed for the control. Four pens of 30 poults and two 3d broiler chicks were placed for the trt group. Trial 2A utilized 296 1d poults and 24 3d broiler chicks. Four trts were randomly divided among 16 pens (20 birds/pen). Trt 1 brooders were placed with assistance finding resources. Trt …
Structure-Function Analysis Of A Protein Encoded By The Bhv-1 Latency Related Gene, Devis Sinani
Structure-Function Analysis Of A Protein Encoded By The Bhv-1 Latency Related Gene, Devis Sinani
School of Veterinary and Biomedical Sciences: Dissertations, Theses, and Student Research
Bovine herpes virus 1 (BHV-1) is a significant viral pathogen in cattle that induces a myriad of clinical symptoms. These symptoms include: conjunctivitis, upper respiratory tract infections, genital disorders, and abortions. BHV-1 infection can also lead to transient immune-suppression, which predisposes cattle to secondary bacterial infection leading to life-threatening pneumonia referred to as bovine respiratory disease (BRD). Following acute infection, BHV-1 establishes latency in sensory neurons within trigeminal ganglia. Reactivation of the virus can occur periodically, resulting in virus transmission. The latency-related (LR) RNA is the only abundantly expressed transcript in latently infected sensory neurons and it encodes several proteins, …
A Time Series Analysis Method Using Hidden Variables For Gene Network Reconstruction, Xi Wu
A Time Series Analysis Method Using Hidden Variables For Gene Network Reconstruction, Xi Wu
Dissertations
The DNA microarray technology can be applied to obtain time series data which contains thousands of genes and tens of time points. When confront the great amount of data points a fast and effective method must be constructed to extract useful information. The assumption that the interactions between genes are static in the time series data is made. After made the assumption how to reconstruct those interactions becomes a difficulty problem. Since the underlying interactions between genes are complicated, which involve transcription, translation and protein-protein interaction, to construct a model from physicochemistry is almost impossible/effortless. The popular methods constructed from …