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Articles 901 - 930 of 3160
Full-Text Articles in Life Sciences
A Tale Of Two Species: Black-Tailed And White-Tailed Prairie Dog Biogeography From The Last Interglacial To 2070, April Dawn Bledsoe
A Tale Of Two Species: Black-Tailed And White-Tailed Prairie Dog Biogeography From The Last Interglacial To 2070, April Dawn Bledsoe
Electronic Theses and Dissertations
Ecological niche models (ENMs) were created for White-tailed and Black-tailed prairie dogs and projected into the Last Interglacial (LI), the Last Glacial Maximum (LGM), and mid-Holocene (mid-H) to discern possible past suitable habitat for both species. Additionally, ENMs were projected into the future year 2070 representative concentration pathways (RCPs) 2.6 and 8.5 to discern how climate change may affect future habitat suitability. Kernel density estimations, minimum convex polygons, and median distribution centers of White-tailed and Black-tailed occurrence records were examined between time-periods to discern the effects of anthropogenic westward expansion on both species’ distributions. Current ENMs were constructed from commonly …
Effects Of Increased Atmospheric Carbon Dioxide Levels On Tobacco Mosaic Virus And Root-Knot Nematodes In Genetically Resistant And Susceptible Tomato Plants, Angie Nicholas
Electronic Theses and Dissertations
Rising atmospheric carbon dioxide (CO2) may affect plant/pathogen interactions. This study focused on the effects of elevated CO2 on Root-Knot Nematode (Meloidogyne arenaria) and Tobacco Mosaic Virus (TMV) infection in genetically resistant versus susceptible tomatoes (Solanum lycopersicum). Both resistant and susceptible tomatoes were grown in chambers with either ambient CO2 or CO2 elevated to 750 ppm and infected with M. arenaria or TMV. Measurements were taken at regular intervals to determine the effects of the pathogens on the plants. Resistant plants infected with M. arenaria maintained resistance while susceptible plants remained …
Soil Nutrient And Contaminant Assessment In Community Gardens, Louisville, Kentucky., Jessica Lynne Eggleston
Soil Nutrient And Contaminant Assessment In Community Gardens, Louisville, Kentucky., Jessica Lynne Eggleston
Electronic Theses and Dissertations
Urban population impact on environmental warming has inspired interest in vegetative coverage to mitigate human influence. Community gardens are proposed to increase green space and access to fresh food, improve health, and quality of life. The potential for soil contamination in post-industrial cities is high presenting a health risk for gardeners. Three Louisville, Kentucky community gardens were chosen for analysis of soil texture, pH, concentration of trace nutrients and metals using Mehlich 1 Extraction. In two community gardens, relative absence of heavy metals suggest they are currently safe for gardening. One garden had a concentration of copper and zinc over …
Tobacco Enhances Bacterial-Induced Periodontal Bone Loss In Mice., Mina Iskander
Tobacco Enhances Bacterial-Induced Periodontal Bone Loss In Mice., Mina Iskander
Electronic Theses and Dissertations
Background: Tobacco smoking is the leading environmental risk factor for periodontal diseases. Delineation of the mechanisms underlying tobacco-induced or exacerbated periodontitis is hampered by the lack of an appropriate and reliable animal model. Hypothesis: We hypothesized that Porphyromonas-gingivalis-infected, cigarette smoke-exposed mice would represent reproducible models of acute (ligature model) and chronic (oral gavage model) tobacco-enhanced periodontitis that reflect multiple aspects of the disease noted in human smokers. Methods: In a chronic oral gavage disease model, Balb/c mice (6-8 weeks, 4 groups of n = 6 per group) were exposed to smoke produced by a Teague-10 smoking machine from 1R6F research …
Bilateral Muscle Oxygenation Kinetics In Response To Repeat Sprint Cycling In Strong And Weak Individuals, John Abbott
Bilateral Muscle Oxygenation Kinetics In Response To Repeat Sprint Cycling In Strong And Weak Individuals, John Abbott
Electronic Theses and Dissertations
Repeat sprint ability has been investigated thoroughly, however optimal training methodology to improve RSA remains elusive. Both kinetic and physiological viewpoints have been used to scrutinize aspects of RSA including, initial sprint performance (anaerobic power), maximal cardiorespiratory fitness (VO2max), lactate threshold, anaerobic capacity (mean power), muscle activation (EMG), and local muscle oxygenation kinetics. To our knowledge no study has utilized maximal strength levels as a separate factor among a homogenous group of cardiorespiratory fitness individuals (as determined by peak VO2 during RSA). The purpose of this study was to better understand the relationship between maximal strength, muscular characteristics, and cycling …
Glare Reduction By Dark Facial Markings And Bills In Birds, Clara Lebow
Glare Reduction By Dark Facial Markings And Bills In Birds, Clara Lebow
Electronic Theses and Dissertations
Avian facial plumage, bill coloration, and feather microstructure may serve one or more adaptive functions. Several researchers have proposed that dark eyestripes, bills, and facial masks aid in reducing glare, however, there have been relatively few tests of this hypothesis. Dark facial markings have been shown to have an adaptive glare-reduction function in recent field studies of a few species, but this hypothesis has never been tested in a broad multispecies analysis. It is likely that feather microstructure influences feather brightness and has an effect on the efficacy of glare reduction properties of feathers. I examined the link between dark …
Effects Of Pre-Workout Caffeine Supplementation On Post-Exercise Hypotension, Shelby L. Gibbs
Effects Of Pre-Workout Caffeine Supplementation On Post-Exercise Hypotension, Shelby L. Gibbs
Electronic Theses and Dissertations
Post-exercise hypotension (PEH) is believed to play a major role in the antihypertensive health benefits of exercise. While it has been shown that resistance exercise is effective at eliciting PEH, commonly consumed sports supplements may attenuate or completely eliminate that response. Caffeine, a popular stimulant, is often consumed prior to exercise. Therefore, the purpose of this study was to investigate the effects of pre-workout caffeine supplementation on the post-exercise hypotensive response in adults with above normal blood pressure. Participants (n = 5) were recreationally resistance trained men and women who consumed placebo or caffeine (3 mg/kg bodyweight) 45-minutes prior to …
Efficient Conditional Inactivation Of Rdh10 Reveals Important Role Of Retinoic Acid During Lung Branching Morphogenesis., Nhut Quang Huy Tran
Efficient Conditional Inactivation Of Rdh10 Reveals Important Role Of Retinoic Acid During Lung Branching Morphogenesis., Nhut Quang Huy Tran
Electronic Theses and Dissertations
Birth defects are complicated pathological processes. Many birth defects can be traced back to disrupted regulation of molecular signaling pathways during embryogenesis. One of the most important gene regulatory factors during embryo development is retinoic acid (RA). However, studying the specific roles of RA in each organ during embryogenesis in vivo is challenging. The Sandell laboratory has a conditional mutant mouse model that can potentially be used for studying the role of RA during embryogenesis by inducing stage-specific RA deficiency. This model allows retinol dehydrogenase 10 (Rdh10), a gene required for RA production, to be inactivated at a …
Role Of Plant Volatile Organic Compounds (Vocs) In Seed Priming And Plant-Herbivore Interactions., Abhinav Kumar Maurya
Role Of Plant Volatile Organic Compounds (Vocs) In Seed Priming And Plant-Herbivore Interactions., Abhinav Kumar Maurya
Electronic Theses and Dissertations
This dissertation explores and expands the existing knowledge on the role of plant volatiles in facilitating seed priming and providing direct defense against herbivore. Although the roles of plant volatiles in priming a plant’s defenses and providing direct defense against pests is well known, information regarding their effects on seed and the fitness of future plants and direct toxicity to herbivores is understudied. This dissertation does a thorough examination of these two understudied aspects of plant volatiles and provides novel insight into the role of plant volatiles in seed priming and direct defense (Chapter I). Seeds in the soil can …
Exosomes From Embryonic Stem Cells As A Prophylactic Vaccine Against Lung Cancer., Shuhan Meng
Exosomes From Embryonic Stem Cells As A Prophylactic Vaccine Against Lung Cancer., Shuhan Meng
Electronic Theses and Dissertations
The antigenic similarity between embryos and tumors has raised the idea of using embryonic materials as a preventative vaccine against neoplastic disease. Indeed, a previous study reported that a vaccine comprised of allogeneic murine embryonic stem cells (ESCs) and murine fibroblasts expressing immune-stimulatory granulocyte macrophage-colony stimulating factor (GM-CSF) successfully blocked the outgrowth of an implantable lung cancer (Lewis lung carcinoma; LLC) and lung tumors caused by a combination of a mutagen followed by chronic pulmonary inflammation. However, such a vaccine is obviously impractical for application to humans. The use of fibroblasts to produce GM-CSF is needlessly complicated, and intact live …
The Role Of Inter-Enlargement Propriospinal Neurons In Locomotion Following Spinal Cord Injury., Courtney Therese Shepard
The Role Of Inter-Enlargement Propriospinal Neurons In Locomotion Following Spinal Cord Injury., Courtney Therese Shepard
Electronic Theses and Dissertations
The focus of this dissertation is to explore the functional role of two anatomically-defined pathways in the adult rat spinal cord before and after spinal cord injury (SCI). To do this, a TetOn dual virus system was used to selectively and reversibly silence neurons with cell bodies at spinal segment L2 and projections to spinal segment C6 (long ascending propriospinal neurons, LAPNs) and neurons that originate in the C6 spinal segment and terminate at L2 spinal segment (long descending propriospinal neurons, LDPNs). This dissertation is divided into five chapters. Chapter One provides background information regarding spinal cord injury, locomotion, …
Development Of In Vitro Models To Study The Rapid Extraintestinal Dissemination Of Salmonella., Adarsh Gopinath
Development Of In Vitro Models To Study The Rapid Extraintestinal Dissemination Of Salmonella., Adarsh Gopinath
Electronic Theses and Dissertations
Salmonella appears in the bloodstream of mice in as little as 15 minutes after oral inoculation and establishes persistent colonies in the spleen and liver. While its pathway to blood is undetermined, this phenomenon is dependent on the activity of Salmonella pathogenicity island 2 (SPI-2) coded type III secretion system (T3SS) and CD18+ phagocytes. We hypothesize that dendritic cells associated with the basal face of the gut epithelium, that are naturally migratory and known to sample for luminal antigens directly transport Salmonella to the bloodstream. This process comprises of at least two phases, dissociation and reverse transmigration. We define dissociation …
Dual Role Of Antimicrobial Peptide Cathelicidin In Alcohol-Associated Liver Disease., Fengyuan Li
Dual Role Of Antimicrobial Peptide Cathelicidin In Alcohol-Associated Liver Disease., Fengyuan Li
Electronic Theses and Dissertations
Patients with alcohol-associated liver disease (ALD) have high morbidity and mortality in its severe forms. One of the major features in different forms of ALD is the altered gut microbiota. Antimicrobial peptides (AMPs) play a crucial role in maintaining gut microbiota homeostasis. LL-37 (known as CRAMP in mouse) is the sole member of the human cathelicidin family and has piqued great research interest for its dual role in modulating microbiota and the immune response in metabolic diseases. Inflammasome activation is an important component of the liver pathophysiology in ALD and requires two signals for its full activation to induce the …
Aboveground-Belowground Interactions: Roles Of Soil Biotic And Abiotic Factors On Switchgrass's (Panicum Virgatum) Growth, Defense Against Herbivory And Cell Wall Chemistry., Binod Basyal
Electronic Theses and Dissertations
Plants constantly interact with their biotic and abiotic soil environments. Most terrestrial plants form beneficial associations with soil microbes such as arbuscular mycorrhizal (AM) fungi, which are widely known for their ability to transfer soil phosphorus and nitrogen to the host plants. They help plants tolerate drought stress and improve plant defense against herbivores such as plant-parasitic nematodes (PPNs). This dissertation investigates the role of AM fungi on switchgrass’s (Panicum virgatum) growth, cell wall chemistry, and defense against PPNs using a combination of growth chamber and field studies. Switchgrass is a native warm-season species which is gaining traction as candidate …
Tobacco Product-Derived Aldehydes: Effects On Circulating Angiogenic Cells & Implications For Cardiovascular Disease., Jordan B. Lynch
Tobacco Product-Derived Aldehydes: Effects On Circulating Angiogenic Cells & Implications For Cardiovascular Disease., Jordan B. Lynch
Electronic Theses and Dissertations
Cardiovascular disease (CVD) is the leading cause of death worldwide. Tobacco smoke is the most significant modifiable risk factor in CVD development and contains numerous toxic compounds, including aldehydes, which have been linked to CVD. Formaldehyde, acetaldehyde, acrolein, and crotonaldehyde have been identified as significant contributors to cigarette-induced health effects, but the mechanism of these effects is not well understood. These aldehydes are also found in aerosols produced by e-cigarettes (e-cigs). The goal of this dissertation was to explore the systemic, hematological, and endothelium-related effects of exposure to tobacco products and constituent aldehydes and to identify potential mechanisms of injury. …
The Retinoblastoma Protein Mediates Metabolic Reprogramming In Lung Cancer., Lindsey R. Conroy
The Retinoblastoma Protein Mediates Metabolic Reprogramming In Lung Cancer., Lindsey R. Conroy
Electronic Theses and Dissertations
Lung cancer is among the most frequently diagnosed cancers and is the leading cause of cancer-related deaths worldwide. One of the hallmark events in lung cancer pathogenesis is deregulation of the cell cycle. The retinoblastoma protein (pRb) is a tumor suppressor that is deleted, mutated, or inactivated in most lung cancer cases. Canonically, pRb functions to regulate cell cycle progression by repressing the transcriptional activity of the E2F family of transcription factors, inhibiting S phase entry. Although the cell cycle functions of pRb have been well established, recent studies have highlighted a functional role for pRb in controlling cellular metabolism. …
Volatile Organic Compound Exposure And Cardiometabolic Syndrome Risk In A Nationally Representative Cohort., Stacey Lane Konkle
Volatile Organic Compound Exposure And Cardiometabolic Syndrome Risk In A Nationally Representative Cohort., Stacey Lane Konkle
Electronic Theses and Dissertations
BACKGROUND: The relative importance of environmental exposures such as volatile organic compounds (VOCs) is one of the paramount public health priorities of our time, yet is presently unstudied. VOCs are ubiquitous in the environment and have been associated with numerous adverse health effects, including a number of cardiovascular and metabolic effects that are components of Cardiometabolic Syndrome (CMS). OBJECTIVES: To examine the relationship between CMS and individual-level exposures to VOCs, measured as urinary metabolites of VOCs (UM-VOCs), in a nationally representative sample. METHODS: Associations between urinary biomarkers of exposure to 19 parent VOCs and CMS were assessed using the National …
Anxiety And How To Control It: The Functional Role Of The Bed Nucleus Of The Stria Terminalis., Lindsay K. Knight
Anxiety And How To Control It: The Functional Role Of The Bed Nucleus Of The Stria Terminalis., Lindsay K. Knight
Electronic Theses and Dissertations
Anxiety disorders afflict up to one third of the population. Research to date has primarily focused on the amygdala, however, new perspectives suggest that a tiny basal forebrain region known as the bed nucleus of the stria terminalis (BNST) may hold key insights into understanding and treating anxiety disorders. Therefore, my first aim was to empirically investigate the importance and influence of the BNST in anxiety processing. Using fearful faces and human screams as aversive stimuli, two threat conditions were created: one in which threats were certain and predictable (fear) and another in which threats were uncertain and unpredictable (anxiety). …
The Cardiovascular Effects Of Tobacco Product-Derived Aldehydes: Contribution Of Transient Receptor Potential Ankyrin-1., Lexiao Jin
Electronic Theses and Dissertations
Cardiovascular diseases (CVD) are the leading cause of death in most countries and are significant health and financial burden worldwide. Smoking contributes to more than 480,000 premature deaths annually -- accounting for one of every five deaths in the United States each year. Numerous studies have shown that smoking increases the risk of factors including endothelial dysfunction, thrombosis, and atherosclerosis, which may lead to an incidence of myocardial infarction, coronary artery disease, and stroke. Electronic cigarettes (e-cigarettes) are a new kind of tobacco product, and some studies show that e-cigarettes also could induce CVD since both e-cigarettes and conventional tobacco …
Tobacco-Derived Aldehydes: Platelet Activation, Thrombosis, And The Role Of Trpa1., Andre Dwayne Richardson
Tobacco-Derived Aldehydes: Platelet Activation, Thrombosis, And The Role Of Trpa1., Andre Dwayne Richardson
Electronic Theses and Dissertations
Cigarette smoking is the single largest risk factor for cardiovascular disease (CVD) pathophysiology. Numerous researchers have shown potential associations between aldehydes in tobacco-derived aerosols from mainstream cigarette smoke (MCS) or electronic cigarettes (e-cigs) and their cardiotoxicity by damaging blood vessel endothelium. The severity of exposure to these toxicants can furthermore lead to adverse cardiovascular outcomes such as myocardial infarctions, stroke, coronary and peripheral artery disease, or atherosclerosis due to blood clots, a pro-thrombotic event. However, the mechanisms by which levels of harmful and potentially harmful constituents (HPHCs) such as aldehydes induce thrombosis are not well-known. Of specific interest, evidence has …
The Effects Of Resistance Deception On Muscular Strength, Muscular Endurance, And Perceived Exertion, Broderick L. Dickerson
The Effects Of Resistance Deception On Muscular Strength, Muscular Endurance, And Perceived Exertion, Broderick L. Dickerson
Electronic Theses and Dissertations
Resistance deception during training is a lightly researched topic and is seen as a modification that can potentially act on central control during exercise. Studies that have observed effects of deception while training have yielded mixed results. The effects of deception on strength, muscular endurance, and perceived exertion and the mechanisms of action that may elicit changes are still unclear. Therefore, the purpose of this study is to determine the effects of resistance deception on muscular strength, muscular endurance, and perceived exertion in a trained population. Eight participants finished the study and underwent four trials, one of which was a …
Personality In Stomatopod Crustaceans, Jillian Page Blenderman
Personality In Stomatopod Crustaceans, Jillian Page Blenderman
Electronic Theses and Dissertations
Stomatopods, or mantis shrimp, are small, predatory crustaceans of tropical and subtropical waters. Mantis shrimp research has focused largely on their agonistic interactions and complex visual systems. Despite their broad behavioral repertoire, stomatopods have not yet been investigated for consistent behavioral differences at the individual level, referred to as animal personality. Fifteen individual Neogonodactylus oerstedii were tested in three scenarios designed to measure potential differences in behaviors: 1) exploration of a novel environment, 2) response to and recovery from a startling event, and 3) response to a novel object. Each individual went through the series of tests twice, with a …
Examining Artifacts Of The Watershed Segmentation, Emily Jo Armitage
Examining Artifacts Of The Watershed Segmentation, Emily Jo Armitage
Electronic Theses and Dissertations
The watershed segmentation is an algorithm used to systematically track cell intercalary behaviors during germ band extension of the Drosophila embryo. Neighboring cells share a contracting vertical interface, called a T1, which continues contracting to a single point, a T2, and extending in the horizontal direction to create what is called a T3 interface (Fig. 1). Additionally, higher order vertices called rosettes occur when five or more cells meet at a common vertex. Simulated T2 events demonstrate that cell angle and not noise level in the image contributes to the incorrect detection of artifactual T1s in more acute angled cells …
Quantification Of Mitochondrial Zinc Homeostasis And Analysis Of Zinc And Polyamine-Mediated Axonal Trafficking, Dylan Hunt Fudge
Quantification Of Mitochondrial Zinc Homeostasis And Analysis Of Zinc And Polyamine-Mediated Axonal Trafficking, Dylan Hunt Fudge
Electronic Theses and Dissertations
The zinc ion is an important emerging signaling molecule for biological processes. In this work we engineered improved zinc sensors based on our previously developed fluorescent sensor GZnP1 to provide sensors with a higher fluorescent readout, faster kinetics, and a superior sensitivity to zinc. We utilized these zinc sensors and further developed the sensors to answer questions pertaining to biological zinc. We showed the labile zinc concentration in the mitochondrial matrix was less than 1 pM while the labile zinc concentration in the cytosol and mitochondrial IMS were comparable (~100 pM) across four different cell lines. Using these zinc sensors …
Epochs Of Ecology: The Transition From Feudalism To Capitalism, Jacob Alexander Tucker
Epochs Of Ecology: The Transition From Feudalism To Capitalism, Jacob Alexander Tucker
Electronic Theses and Dissertations
The transition from feudalism to capitalism has undoubtedly been one of the most fruitful and complicated debates amongst economic historians in the 20th and 21st centuries. With the advent of global ecological collapse, there is a necessity to examine and theorize the movement from feudalism to capitalism through the lens of ecology. While in mainstream economics the environment is either entirely dismissed or nature’s role in economics remains subsidiary to the human economy, in the field of Marxian economics, human’s interacting through nature is at the core of the entire theory. For that reason, this thesis takes earnestly Marx’s contributions …
Cellular And Developmental Insights Into The Early Evolution Of Muscle, Jeffrey J. Colgren
Cellular And Developmental Insights Into The Early Evolution Of Muscle, Jeffrey J. Colgren
Electronic Theses and Dissertations
Whereas a great deal has been learned about the molecular underpinnings of morphological evolution in animals, much less is known about the origin of novel cell and tissue types. During the time in which the earliest animal lineages were diversifying, fundamental cell and tissue types, such as muscles, arose. Sponges are one of two animal lineages that lack muscles, yet they undergo coordinated full body contractions. Whereas the signaling processes have been studied, the physical mechanisms of contraction are completely uncharacterized. The main purpose of this work is to understand the primary contractile tissue of the sponge Ephydatia muelleri, …
Subalpine Forest Tree Seedling Response To Drought, Alex Goke
Subalpine Forest Tree Seedling Response To Drought, Alex Goke
Electronic Theses and Dissertations
Knowledge of tree species’ ability to tolerate drought is necessary to anticipate future forest dynamics with climate change, especially at the seedling stage given their role in shaping forest structure. We used precipitation reduction shelters to mimic drought for subalpine conifer seedlings (A. lasiocarpa and P. engelmannii) in the Rocky Mountains and compared survivorship and morphological and physiological responses to assess relative degrees of drought tolerance. We detected no significant investment in morphological tolerance traits (e.g. root biomass, leaf:stem area ratio) but substantial reductions in net photosynthesis. While shading partially ameliorated drought effects when precipitation reduction was moderate, …
Ehbp1 And Ehd2 Regulate Dll4 Caveolin-Mediated Endocytosis During Blood Vessel Development, Amelia Margaret Webb
Ehbp1 And Ehd2 Regulate Dll4 Caveolin-Mediated Endocytosis During Blood Vessel Development, Amelia Margaret Webb
Electronic Theses and Dissertations
During angiogenesis, the development of new blood vessels from existing vessels, there must be tight regulation between a leading tip cell and trailing stalk cells during vascular patterning. Lateral inhibition produced by Notch signaling is central to the specification and maintenance of tip and stalk cells in growing angiogenic sprouts. The Notch pathway is activated by the ligand Delta at adherens junctions between tip and stalk cells. Despite the centrality of Delta/Notch signaling to angiogenesis, relatively little is known about the mechanism of this signaling event. It has been proposed that the force generated by the Notch bound Delta ligand …
Characterization Of The Dimerization And Salt Dependent Aggregation Of The Als-Linked Protein Tdp-43, Elizabeth Ehrhardt
Characterization Of The Dimerization And Salt Dependent Aggregation Of The Als-Linked Protein Tdp-43, Elizabeth Ehrhardt
Electronic Theses and Dissertations
Trans-active response (TAR) DNA-binding protein 43 (TDP-43) is essential for RNA processing but can also form toxic cytoplasmic inclusions in neurons of patients with amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration (FTLD). RNA-binding has been shown to have the potential to decrease or inhibit the aggregation of TDP-43, indicating that supplying RNA therapeutics may be a solution to treat these neurodegenerative disorders. However, the mechanism of aggregation, transitioning from TDP-43’s native dimeric state to small oligomers to toxic aggregates, is still relatively unknown. This needs to be established before determining how to target and disrupt this aggregation. Using GFP-TDP-43, …
Land Use Influences Along Elevation Gradient On Macroinvertebrate Communities, Brittany Sprout
Land Use Influences Along Elevation Gradient On Macroinvertebrate Communities, Brittany Sprout
Electronic Theses and Dissertations
Land use activities have caused disturbances that affect the quality of freshwater ecosystems worldwide. How the influences of land use along an environmental gradient and the associated environmental variables that may influence stream diversity and function is unclear. We address these issues by studying biodiversity, abundance, and functional diversity of macroinvertebrates across different land types along a gradient in Colorado, USA. We also address how diversity may change along an elevation gradient by analyzing previously published macroinvertebrate research. We found evidence that land use and disturbance are stronger explanations of changes in macroinvertebrate communities, rather than elevation. Functional trait patterns …