Life Sciences Commons^™

Role Of Interleukin 2 Receptor Alpha In The Cellular Response To Dna Damage, Shristi Khanal

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The interleukin 2 receptor alpha (IL-2Rα), which is integral to the functioning of the cytokine interleukin 2, has recently been found to be present in different cell types besides just lymphocytes. Previous studies done by our laboratory showed that several other non-lymphoid cells including smooth muscle cells express IL-2Rα. Vascular smooth muscle cell (VSMC) deficient in IL-2Rα exhibited increased proliferation, decreased size, and hypodiploid DNA content when compared to wild type (WT) cells. Previous studies also suggested that VSMC proliferate in response to IL-2 and that IL-2 increases following interventions to stimulate intimal hyperplasia in vivo. These findings, in total, …

Exploring The Effects Of Choline Treatment On Dystrophic Phenotype, Brooklyn Morris

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Duchenne Muscular Dystrophy (DMD) is a devastating progressive muscular disorder caused by a mutation in the dystrophin gene affecting approximately 1 in 3,500 males. However, despite its prevalence, there is currently no cure for this disease. Mutations in dystrophin lead to enhanced inflammation, fibrosis, cell death, development, and decreased skeletal muscle function. Phosphatidylcholine, synthesized by choline, is a major phospholipid that functions in maintaining and synthesizing cell membranes and has previously been found to be decreased in DMD patients. This led us to hypothesize that the dystrophic phenotype could be improved through treatment with choline. In this study, we used …

Studies Of Selective And Reversible Inhibitors Of Calcium Entry In Immune Cells, Naga Lakshmi Gandi

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Calcium signaling is a crucial regulator in many cellular processes, from immune response modulation to gene expression and apoptosis. Here, I have investigated the dynamics of calcium entry pathways, namely, store-operated calcium entry and store-independent calcium entry using a variety of cell types such as Jurkat T cells, HEK-293 cells and murine macrophages. Using fluorescence calcium imaging and selective inhibitor compounds, I have investigated the contributions of Orai and related calcium channels to calcium entry in both immune and non-immune cell types. The results demonstrate the pharmacological modulation of store-operated and store-independent calcium entry, showing the ability of compounds such …

Investigating The Effects Of Human Astroviruses On Aquaporins And Tight Junction Proteins In Vitro, Makalia T. Robinson

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Human Astroviruses (HAstV) are positive sense non-enveloped single stranded RNA viruses. HAstV is divided into classical (serotype 1-8) and non-classical (HAstVMLB 1-3 and HAstV-VA1-5) astroviruses. Classical HAstV is known to cause diarrhea in children, elderly, and immunocompromised patients. Additionally, the etiology of nonclassical HAstV remains unknown. However, recent studies have implicated non-classical HAstV closely associated with immunocompromised patients diagnosed neurological diseases like acute encephalitis. The mechanisms by which HAstV cause diarrhea is currently unknown. Aquaporins (AQPs) are integral membrane proteins that regulate the movement of water and small uncharged molecules across the cell membrane in response to osmotic gradients. Tight …

Microbes Mediated Keratin Extraction From Poultry Waste And Assessment Of Its Efficacy In Growth Promotion Of Zea Mays And Triticum Aestivum, Imran Ahmad, Aisha Waheed Qurashi, Roheela Yasmeen

Journal of Bioresource Management

Feathers are a waste product of the poultry industry and are considered a major pollutant of the environment. Soil associated with poultry farms is a rich source of indigenous bacteria that are involved in biodegradation of keratin of the feathers of Gallus gallus domesticus. The present study was designed to understand the role of microbes in the degradation of a feather’s keratin and its possible utilization as a bio-protein for plants. In our studies, Keratinolytic activity was high at 37-45 ℃ and at 7.5-9.5 pH. Pseudomonas aeruginosa was identified by 16S rRNA sequencing as the most active keratinolytic strain. …

Review On Locusta Migratoria Cinerascens (Fabricius, 1781)., Laib Djamel Eddine, Benzehra Abdelmadjid, Laib Imen, Aouzal Badis, Salah Akkal

Journal of Bioresource Management

The migratory locust, scientifically known as Locusta migratoria (Linnaeus, 1758), is a captivating insect species that has drawn the interest of scientists, farmers, and the general public. Recognized for its notorious swarming behavior, this insect has the potential to cause extensive damage to crops, leading to agricultural plagues and food shortages. However, beyond its reputation as a pest, the migratory locust is a subject of scientific fascination due to its intricate life cycle, remarkable ability to undergo rapid and dramatic transformations, and its crucial role within the ecosystems it inhabits. This review delves into various facets of L. migratoria, including …

Moth Species Diversity, Composition And Abundance In Different Land Use Types Of Chebera Churchura National Park And Its Surroundings, Southwestern Ethiopia, Gebreegziabher Hailay, Emana Getu

Journal of Bioresource Management

Land use change and habitat fragmentation affect biodiversity through an increasing level of disturbance and destruction of natural habitats. The present study is the first report on species diversity, species composition, and abundance of moth fauna in and around Chebera Churchura national park. During the survey from January to June 2021, 6206 specimens were collected from 105 species and 11 families from the 3 land use types. Based on the number of species, the family Erbidae is the most abundant with 41 species, and the family Pyraldae was the least abundant with one species. Based on the number of individuals, …

Establishment Of Hand Rearing Protocols With Respect To Feeding, Physiological And Behavioral Aspects In Abandoned Lion Cubs At Safari Zoo Lahore, Muhammad Azhar, Bushra Nisar Khan, Fahd Haseeb, Muhammad Hassan Saleem, Abdul Rehman, Zahid Iqbal Khan, Muhammad Rizwan Khan

Journal of Bioresource Management

African lion (Panthera leo) being most attractive but vulnerable exhibit of zoos and safaris; need particular attention to breeding plans. At captive sites, lioness neglects newborns commonly; at that stage, hand rearing is preferred. This study will highlight the best practices for hand-rearing lion cubs, including knowledge of early medical issues along with their treatment during the first 4 months of growth. 34 lions (08Male: 17Females: 9Cubs) were housed on 15 acres during 2019-21 at Safari Zoo Lahore. A total of 04 lionesses were found entirely abandoned to 05 newborns (03 males & 02 females). The hand-rearing period …

Role Of Urban Parks In Carbon Sequestration– A Case Study Of Safari Park, Karachi, Pakistan, Amna Bano, Minzah Shehzad, Hasnain Kazmi, Jamshaid Iqbal

Journal of Bioresource Management

Urban parks besides their recreational use can be the potential source of climate mitigation through carbon sequestration. Present study aims to identify the carbon sequestration potential of Safari Park which is by far the largest public park of Karachi established in 1970 covering an area of 0.72 km². A total of 153 individual trees belonging to 25 species and 14 families were included in the study. Five dominant species with highest Important Value Index (IVI) were Cocos nucifera (14.62 %), Azadirachta indica (14.21 %), Guaiacum officinale (9.93 %), Washington robusta (9.31 %) and Delonix regia (7.11 %). The …

Food Additive Evidence In Food Supplements Most Commonly Consumed By Cancer Patients, Safa Mazouzi, Samira Djekoun Bensoltane, Sabiha Bouzbid, Nesrine Adjabi

Journal of Bioresource Management

The goal of this research is to highlight food additives in the formulations of food supplements consumed by cancer patients. It is a survey conducted at the Cancer treatment center in Annaba to collect a list of food supplements used by these patients. Following a screening of their ingredients for incorporated food additives, which we then classified according to the degree of toxicity, these supplements were classified according to their origin (local or imported). Our findings show that these various groups of dietary supplements contain a variety of food additives with varying degrees of toxicity, such as colorants (E422), acidity …

Comparative Histological Study On The Algerian Thymus Ciliatus At Different Phenological Stages, Nina Sadou, Ratiba Seridi, Hamdi Bendif

Journal of Bioresource Management

The aim of the current study was to compare the histological observations of stems, leaves, and different secretory structures of Thymus ciliatus at three phenological stages. The anatomical observations of stems, leaves, and glandular trichomes were carried out by light microscopy. The results showed that phenological stages do not affect significantly the anatomical, whereas there was a significant increase in secretory trichomes. The glandular trichomes are distributed on the surface of the stems and the leaves. There are only two distinct types of secretory trichomes, Peltate consisting of a basal cell, a stalk cell, and an 8-celled head type, which …

Utilizing An Extract From Endophytic Fungus, Alternaria Alternata, Isolated From Ricinus Communis L. Leaves As A Biological Agent For Controlling The Migratory Locust In Algeria, Laib Djamel Eddine, Benzehra Abdelmadjid, Laib Imen, Aouzal Badis, Akkal Salah

Journal of Bioresource Management

In this research, we aimed to explore the insecticidal potential of Alternaria alternata, an endophytic fungus derived from the leaves of castor oil plant. To test its insecticidal efficacy, various doses of A. alternata mycoextract were administered to Locusta migratoria L. through both topical and oral pathways. The findings revealed that the insects displayed the highest susceptibility to a concentration of 2 g/L, leading to an impressive mortality rate of 87.5 % and 93.75 % for topical and oral administrations, in the same order. The extract displayed remarkable insecticidal properties, demonstrating LC50 values of 1.09 g/L for the topical …

Comprehensive Assessment Of Economic, Productive, Phenotypic, And Morphometric Traits In Azikheli Buffalo Breed Of Northern Pakistan, Nadar Khan, Bakhtawara Bibi, Tariq Ahmad, Salman Khan, Aamir Khan, Muhammad Ibrahim

Journal of Bioresource Management

The study was conducted to illuminate the phenotypic, morphometric, and productive characteristics of the Azikheli buffalo breed. One thousand two hundred pure Azikheli buffaloes (male: female) were randomly selected from the main hub of the Azikheli buffalo breed in Swat (Azikhel). The data were analyzed for comparison and frequency distribution. Phenotypic characteristic of the female buffalo shows that more than 73 % of the body color was golden yellowish. In contrast, in males, this value was 83 %, followed by white-albino and grayish colors. The shape of horns were semi sickle and grayish in color. Morphometric parameters of the breed …

Ethnobotanical Study Of Antihemorrhagic Plants In The Skikda Region (North East Of Algeria), Nabila Souilah, Hamdi Bendif, Abdelkrim Benaradj, Abdelouaheb Belaid, Scherazad Mekious

Journal of Bioresource Management

Our survey was carried out at the level of 17 Municipalities of the Province of Skikda. Questionnaire sheets were distributed to 55 herbalists and 350 locale population (informants). The processing of survey data with the local population shows us that women (52 %) have more knowledge of phytotherapy compared to men (48 %) with a fairly high level of education. For the herbalists, we found that most are men (85.45 %) aged between 31-40 years (29.09 %) and 41-50 years (25.45 %), and with level of university study (36.36 %). On the other hand, 52.73 % of herbalists said they …

Description Of Sivalhippus (Equidae: Perissodactyla) From The Late Miocene Siwalik Sub-Group Of Pakistan, Muhammad Tahir Waseem, Ayesha Iqbal, Sania Zubaid, Abdul Majid Khan, Muhammad Ammar

Journal of Bioresource Management

New fossil mandible as well as isolated upper and lower dentitions of the late Miocene Hipparionine species, have been discovered from a locality of Chakwal, Punjab, Pakistan. By using morphometric and morphologic analysis, we have deduced that these specimens belong to Sivalhippus theobaldi. The body size of this species was intermediate between Sivalhippus perimensis and Hipparion antilopinum while its hypsodonty indicates that this species was a grazer to a larger extent which existed in mosaic of woodland and grassland in the Latest Miocene. However, the comparison with the recent horse (Equus caballus) mandible indicates some differences in …

Hepatoprotective Effect Of Berberis Lycium In Αlpha-Naphthylisothiocyanate Induced Cholestatic Mouse Models, Shamaila Bashir, Hassan Hameed, Nida Irshad, Aqsa Ashraf, Muhammad Faizan, Saiyada Fatima Maida Halim, Hafiz M. Mazhar Asjad, Andleeb Batool, Imran Sohail

Journal of Bioresource Management

Cholestasis is characterized by the obstruction of bile flow from hepatocytes to the intestine. It results in accumulation of bile acids in the liver, which cause oxidative stress, inflammation, apoptosis, fibrosis, and cirrhosis. Till now, the treatment options against cholestasis are limited. Therefore, there is an utmost requirement to develop and evaluate the drugs with potential anti-cholestatic effects. In the current study, the drug-induced cholestasis mouse models were generated via oral administration of α-naphthylisothiocyanate (ANIT). The mice were placed into three groups of six animals each. Group I was the control group and was given saline. The cholestasis model Group …

Evaluating Microbial Contamination Of Bakeries, Wheat Flour In Ghaemshahr, Iran, Reyhaneh Gouran, Nazanin Khakipour

Journal of Bioresource Management

Although flour is regarded as a safe product from the perspective of microbiology due to its low water activity, it can be a suitable environment for the growth of microorganisms if suitable conditions are provided for their growth and reproduction. The objective of this study was to examine the microbial quality of 82 % and 78 % flours distributed in 5 bakeries in the city of Ghaemshahr. The evaluation of the results of the physicochemical tests on the samples revealed that sample No.5's moisture content (82 % of the flour sample from the bakery E) was significantly higher than other …

Population Density Of Grey Francolin (Franclinus Pondicrianus L.) In District Tando Allahyar, Sindh, Pakistan, Rameez Raja Kaleri, Hubdar Ali Kaleri, Ghulam Mustafa Solangi, Raza Ali Mangi, Abdul Wahid Solangi, Zahid Ali Mangrio, Farooque Ahmed Khushk, Muhammad Anees Memon, Muhammad Awais Soomro, Depeesh Kumar Bhuptani, Imran Ahmed

Journal of Bioresource Management

The population density of Grey Francolin (Franclinus pondicrianus L.) is distributed throughout the Baluchistan, KPK, Punjab, and Indus plains of Sindh Province, Pakistan. The grey francolin is a prime game bird of our country. This species has been declared threatened worldwide according to the Red Data Book, also published by the International Union for Conservation of Nature in 2018. There is no information available regarding the density of the population of Grey francolin in different populations in the district of Tando Allahyar, Sindh, Pakistan. Keeping this in mind, the present study was carried out to find the density …

Optimizing Conservation Of Nili Ravi Buffaloes In Southern Region Of Khyber Pakhtunkhwa: A Comprehensive Evaluation Of Phenotypic, Morphometric, And Productive Traits, Arsalan Khan, Israr Ud Din, Hafiz Abdul Majid, Amjad Ali, Akhtar Ali, Muhammad Rizwan, Waseem Ullah, Shah Zeb, Safi Ullah, Imran Khan, Abid Ullah

Journal of Bioresource Management

In Pakistan, Nili Ravi buffalo is highly valued breed due to its high milk yield. Native to Punjab province, the breed is now extensively distributed throughout the country. To assess and optimize the conservation strategies for Nili Ravi buffaloes in southern Khyber Pakhtunkhwa by evaluating their phenotypic, morphometric, productive, and reproductive characteristics. Buffaloes were maintained at Livestock Research and Development Station in Paharpur, Dera Ismail Khan from 2010-2023, under breed conservation program. A sum of 298 records Nili Ravi buffaloes were used for the investigation. The research examined physical attributes such as coat color, horn morphology, and other qualitative characteristics. …

Domestication Trial Of Synsepalum Stipulatum (Radlk.) Engl. In The Humid Tropical Climate Of Kinshasa, Patrick Dande, Bakapana Souza, Jeanne Kwambanda, Eustache Kidikwadi, Honoré Belesi, Constantin Lubini

Journal of Bioresource Management

The present study deals with the domestication trial of Synsepalum stipulatum (Radlk.) Engl. in the humid tropical climate of Kinshasa and aims at contributing to the domestication of the species. To achieve this, proceeded with two methodological approaches: observation and experimentation. The results obtained show that the effect of three seeds treatments: drying of the seeds on the sun, seeds unpulped in the bag kept under the shade for 14 days and no treatment on the germination of Synsepalum stipulatum seeds was evaluated on two types of substrates: potting soil and clay soil. The absence of seed treatment resulted …

Feeding Overlap Investigations Between Hypophthalmichthys Molitrix And Cyprinus Carpio From Punjab, Pakistan, Afzala Munawar, Muhammad Imran, Muhammad Ameen, Abdul Majid Khan, Ayesha Sania, Muhammad Shahbaz

Journal of Bioresource Management

Freshwater ichthyofauna is facing intensive stress as a result of urbanization and growing industries in Pakistan. The alien fish species are considered one of the major challenges due to their deleterious effects. Feeding habit analysis is a basic tool to evaluate the ecological stress on fish species residing in different habitats. The present study was designed to disclose the feeding overlap between Cyprinus carpio (Common Carp) and Hypophthalmichthys molitrix (Silver Carp) from Head Marala (river Chenab) and Mangla Dam (river Jhelum). For this purpose, 20 samples i.e. 10 from each site of each fish species out of total 40, were …

Biology, Ecology, Infestation, And Management Of Warble Flies (Diptera: Oestridae), Muhammad Jamil, Abdul Razzaq, Noman Latif, Mariam Fatima, Muhammad Saqib, Matiullah Jaffar, Hafiz Zille Rehman, Faiqah Ramzan

Journal of Bioresource Management

The range grazing livestock (cattles and goats) are afflicted by a significant skin/hide issue known as warble fly larval infestation, which is caused by the larvae of Hypoderma lineatum and Hypoderma bovis species which resulted in substantial economic losses to the leather industries. The life cycle of hypodermosis is complex, involving both ecto- and endoparasitic stages. Female warble flies deposit their eggs in rows of 5-8 on individual hairs of the host, often targeting the legs but also other areas. These eggs are securely attached to the hairs and a single female fly may lay as many as 800 eggs …

Isolation And Characterization Of Microbes From Agricultural Fields And Their Evaluation For The Control Of Plant Pests, Hira Liaqat Ali, Sumaira Mazhar, Afeefa Chaudhry

Journal of Bioresource Management

Plant diseases due to pests cause huge loss to crop fields every year. For the control of plant pest, pesticides are under use. Fusarium wilt is caused by phytopathogen Fusarium oxysporum. More than 100 species were affected due to this disease caused by this virus. Fungi also affect onion plant crop yield every year, when chemical pesticides are applied to onion crop field. It will increase the cost of onion production and it is also dangerous for the environment and living organism other than the targeted pests. A number of microorganisms like fungi, bacteria and nematode are currently being …

A Scoping Review Of Wrist-Worn Wearables In Education, Noah L. Schroeder, William L. Romine, Sidney E. Kemp

Biological Sciences Faculty Publications

Within the past ten years, the public's use of wearables, such as smartwatches and fitness trackers, has greatly increased. Recently, researchers have published systematic reviews to examine how wearables are used in educational settings. However, not all wearables are alike. Head-mounted wearables and exoskeletons may be viewed as invasive, whereas smartwatches and wristbands are commonly worn by the public. In this scoping review, we systematically review the literature around wrist-worn wearables (WWs) in educational settings. Our systematic search revealed 1,932 unique research items, of which 46 met the inclusion criteria and were analyzed. Our findings reveal the trends in the …

Send-Off Meditation, Audrey E. Mcgowin

Runkle Woods Symposia

Audrey McGowin wraps up the 6th Annual Wright State Runkle Woods Symposium with some warm words followed by a meditation video. The video is of a Ginko tree's leaf fall with only the ambient noise of the leaves during their descent and gentle impact with the ground.

Building Community Through Nature, Mikusa, Wright State University Nature Club

Runkle Woods Symposia

Undergraduate student Mikusa introduces and speaks about the Wright State University Nature Lovers Club, of which she is the creator and president.

National Wildlife Federation Habitat Certification: A Collaboration With Fairborn?, Alexis Knick, Amanda Taylor

Runkle Woods Symposia

Mandy Taylor and Alexis Knick from the Fairborn Environmental Advisory Board discuss their mission to draft environmental sustainability and resilience plans and how Wright State can help contribute and partner with their mission.

Keynote Address: Seasonal Changes In The Avian Community Of The Wright State Woods, Jeffrey L. Peters

Runkle Woods Symposia

Dr. Jeffrey Peters is a Professor of Biological Sciences at Wright State University. He earned his B.S. in Biology at Indiana University of Pennsylvania. For his M.S. in Applied Ecology and Conservation Biology at Frostburg State University in Maryland, Dr. Peters used DNA analyses to examine mating strategies in a species of duck, the Gadwall. Continuing his genetics research, he studied geographic variation in ducks for his Ph.D. in Biology at the University of Maryland, Baltimore County. Dr. Peters continued this work at the University of Alaska, Fairbanks, as a post-doctoral researcher, and at Wright State University. During his career, …

The Insult Of Road Salt, Rebecca N. Tuttle, Benson Sparkman, Landon Shackleford, Audrey E. Mcgowin

Runkle Woods Symposia

Wright State students Abby Tuttle, Benson Sparkman, and Landon Shackleford present their undergraduate research on the high chloride levels in the Wright State Woods, it's soil and water, caused by the use of winter road salt.

Pawpaws: Ohio’S State Fruit, Don Cipollini

Runkle Woods Symposia

Dr. Don Cipollini presents his episode on Pawpaws from his show The Naturalist followed by a Q&A.

Dr. Cipollini takes us on a walk through the Wright State University Woods and his own backyard to talk about Ohio's state fruit, the Pawpaw and the trees that grow it. He discusses how to grow pawpaw, the biology of the tree, and how you can use and eat the fruit it produces.