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Articles 421 - 450 of 1744
Full-Text Articles in Life Sciences
Exploring The Work-Related Quality Of Life Of Athletic Trainers In Physician Practice, N T. Anderson, K E. Games, J P. Young, M J. Rivera, L E. Eberman
Exploring The Work-Related Quality Of Life Of Athletic Trainers In Physician Practice, N T. Anderson, K E. Games, J P. Young, M J. Rivera, L E. Eberman
Clinical Practice in Athletic Training
Introduction/Context: The National Athletic Trainers’ Association (NATA) identified the vitality of the athletic training profession as a research priority, which includes exploring solutions to improve work-life balance. There is a common perception that athletic trainers (AT) working in the physician practice setting have lower work-life conflict and increased job satisfaction, but no data to support this belief. Work-Related Quality of Life (WRQoL) has been studied in some healthcare settings but has not been studied in any athletic training clinical practice setting. Therefore, the purpose of this study is to investigate the WRQoL of athletic trainers in physician practice. Methods: A …
How Do Athletic Trainers Impact Patient Health Literacy?: A Critically Appraised Topic, T Bouchard
How Do Athletic Trainers Impact Patient Health Literacy?: A Critically Appraised Topic, T Bouchard
Clinical Practice in Athletic Training
Introduction/Context: Health Literacy is defined as “the degree to which individuals have the capacity to obtain, process, and understand basic health information and services needed to make appropriate health decisions.” An estimated 80 million Americans are estimated to have low levels of health literacy. Low health literacy has been linked to poor patient outcomes and decreased usage of health services. Athletic trainers are multiskilled medical professionals recognized by the American Medical Association, trained in, among other things, wellness promotion and education, injury prevention and rehabilitation, and primary care. Although athletic trainers have traditionally been employed in collegiate/elite sports, many are …
International Society Of Sports Nutrition Position Stand: Long-Chain Omega-3 Polyunsaturated Fatty Acids, Alex Leaf, Jeffrey A. Rothschild, Tim M. Sharpe, Stacy T. Sims, Chad J. Macias, Geoff G. Futch, Michael D. Roberts, Jeffrey R. Stout, Michael J. Ormsbee, Alan A. Aragon, Bill I. Campbell, Shawn M. Arent Ph.D., Cscs*D, Fissn, Facsm, Fnak, Dominic P. D’Agostino, Michelle T. Barrack, Chad M. Kerksick, Richard B. Kreider, Douglas S. Kalman, Jose Antonio
International Society Of Sports Nutrition Position Stand: Long-Chain Omega-3 Polyunsaturated Fatty Acids, Alex Leaf, Jeffrey A. Rothschild, Tim M. Sharpe, Stacy T. Sims, Chad J. Macias, Geoff G. Futch, Michael D. Roberts, Jeffrey R. Stout, Michael J. Ormsbee, Alan A. Aragon, Bill I. Campbell, Shawn M. Arent Ph.D., Cscs*D, Fissn, Facsm, Fnak, Dominic P. D’Agostino, Michelle T. Barrack, Chad M. Kerksick, Richard B. Kreider, Douglas S. Kalman, Jose Antonio
Faculty Publications
Position statement: The International Society of Sports Nutrition (ISSN) provides an objective and critical review of the use of a ketogenic diet in healthy exercising adults, with a focus on exercise performance and body composition. However, this review does not address the use of exogenous ketone supplements. The following points summarize the position of the ISSN: 1. A ketogenic diet induces a state of nutritional ketosis, which is generally defined as serum ketone levels above 0.5 mM. While many factors can impact what amount of daily carbohydrate intake will result in these levels, a broad guideline is a daily dietary …
Common Questions And Misconceptions About Protein Supplementation: What Does The Scientific Evidence Really Show?, Jose Antonio, Cassandra Evans, Arny A. Ferrando, Jeffrey R. Stout, Brandi Antonio, Harry Cinteo, Patrick Harty, Shawn M. Arent Ph.D., Cscs*D, Fissn, Facsm, Fnak, Darren G. Candow, Scott C. Forbes, Chad M. Kerksick, Flavia Pereira, Drew Gonzalez, Richard B. Kreider
Common Questions And Misconceptions About Protein Supplementation: What Does The Scientific Evidence Really Show?, Jose Antonio, Cassandra Evans, Arny A. Ferrando, Jeffrey R. Stout, Brandi Antonio, Harry Cinteo, Patrick Harty, Shawn M. Arent Ph.D., Cscs*D, Fissn, Facsm, Fnak, Darren G. Candow, Scott C. Forbes, Chad M. Kerksick, Flavia Pereira, Drew Gonzalez, Richard B. Kreider
Faculty Publications
Protein supplementation often refers to increasing the intake of this particular macronutrient through dietary supplements in the form of powders, ready-to-drink shakes, and bars. The primary purpose of protein supplementation is to augment dietary protein intake, aiding individuals in meeting their protein requirements, especially when it may be challenging to do so through regular food (i.e. chicken, beef, fish, pork, etc.) sources alone. A large body of evidence shows that protein has an important role in exercising and sedentary individuals. A PubMed search of “protein and exercise performance” reveals thousands of publications. Despite the considerable volume of evidence, it is …
Multi-Omics Integrative Analysis For Incomplete Data Using Weighted P-Value Adjustment Approaches, Wenda Zhang, Zichen Ma, Yen Yi Ho, Shuyi Yang, Joshua Habiger, Hsin Hsiung Huang, Yufei Huang
Multi-Omics Integrative Analysis For Incomplete Data Using Weighted P-Value Adjustment Approaches, Wenda Zhang, Zichen Ma, Yen Yi Ho, Shuyi Yang, Joshua Habiger, Hsin Hsiung Huang, Yufei Huang
Faculty Publications
The advancements in high-throughput technologies provide exciting opportunities to obtain multi-omics data from the same individuals in a biomedical study, and joint analyses of data from multiple sources offer many benefits. However, the occurrence of missing values is an inevitable issue in multi-omics data because measurements such as mRNA gene expression levels often require invasive tissue sampling from patients. Common approaches for addressing missing measurements include analyses based on observations with complete data or multiple imputation methods. In this paper, we propose a novel integrative multi-omics analytical framework based on p-value weight adjustment in order to incorporate observations with incomplete …
Genome-Wide Search Algorithms For Identifying Dynamic Gene Co-Expression Via Bayesian Variable Selection, Wenda Zhang, Zichen Ma, Lianming Wang, Daping Fan, Yen Yi Ho
Genome-Wide Search Algorithms For Identifying Dynamic Gene Co-Expression Via Bayesian Variable Selection, Wenda Zhang, Zichen Ma, Lianming Wang, Daping Fan, Yen Yi Ho
Faculty Publications
A wealth of gene expression data generated by high-throughput techniques provides exciting opportunities for studying gene-gene interactions systematically. Gene-gene interactions in a biological system are tightly regulated and are often highly dynamic. The interactions can change flexibly under various internal cellular signals or external stimuli. Previous studies have developed statistical methods to examine these dynamic changes in gene-gene interactions. However, due to the massive number of possible gene combinations that need to be considered in a typical genomic dataset, intensive computation is a common challenge for exploring gene-gene interactions. On the other hand, oftentimes only a small proportion of gene …
The Stress Response Of The Seagrass Zostera Noltei And Three Commercial Clam Species To Low Salinity Associated With Heavy Rainfall, Salvador Román, Elsa Vázquez, Marta Román, Rosa M. Viejo, Nicolás Weidberg, Jesús S. Troncoso, Sarah A. Woodin, David S. Wethey, Celia Olabarria
The Stress Response Of The Seagrass Zostera Noltei And Three Commercial Clam Species To Low Salinity Associated With Heavy Rainfall, Salvador Román, Elsa Vázquez, Marta Román, Rosa M. Viejo, Nicolás Weidberg, Jesús S. Troncoso, Sarah A. Woodin, David S. Wethey, Celia Olabarria
Faculty Publications
The maintenance of stocks of estuarine species strongly depends on the ability of the species to cope with environmental stress. In NW Spain, commercial clam beds, which are usually co-occupied by the seagrass Zostera noltei, are often exposed to reduced salinity caused by intense rainfalls. Our goals were to evaluate the effects of low salinity events on both juvenile clams and Z. noltei, including their interactions. A mesocosm experiment was performed to simulate three salinity decreases (35–35, 25–10, and 20–5), and several indicators of clam and seagrass performance were measured after 3 and 6 days of exposure and …
Effect Of Exercise Training On Lipoprotein Subclass Particle Concentrations And Sizes In Older Women: Results From A Randomized Controlled Trial, Ryan R. Porter, Joshua R. Sparks, J. Larry Durstine, Sabra S. Custer, Raymond W. Thompson, Xuewen Wang
Effect Of Exercise Training On Lipoprotein Subclass Particle Concentrations And Sizes In Older Women: Results From A Randomized Controlled Trial, Ryan R. Porter, Joshua R. Sparks, J. Larry Durstine, Sabra S. Custer, Raymond W. Thompson, Xuewen Wang
Faculty Publications
Background: Evidence suggests that lipoprotein subclass particles are critical markers of cardiovascular disease (CVD) risk. Older women have increased CVD risk related to age. The purpose of this study was to determine whether low and moderate doses of exercise influence lipoprotein subclasses. Methods: Women (60–75 years) were randomized into groups for 16 weeks of moderate-intensity exercise training at a low or moderate dose (33.6 and 58.8 kJ/kg body weight weekly, respectively). Lipoprotein subclasses were determined by nuclear magnetic resonance spectroscopy before and after the training. RESULTS: The average weekly exercise duration was 109 and 164 min, for low- and moderate-dose …
Effect Of Menstrual Cycle And Contraceptive Pill Phase On Aspects Of Exercise Physiology And Athletic Performance In Female Athletes: Protocol For The Feminae International Multisite Innovative Project, Kirsty J. Elliott Sale, Tessa R. Flood, Shawn M. Arent Ph.D., Cscs*D, Fissn, Facsm, Fnak, Eimear Dolan, Bryan Saunders, Mette Hansen, Johanna K. Ihalainen, Ritva S. Mikkonen, Clare Minahan, Jane S. Thornton, Kathryn E. Ackerman, Constance M. Lebrun, Craig Sale, Trent Stellingwerff, Paul A. Swinton, Anthony C. Hackney
Effect Of Menstrual Cycle And Contraceptive Pill Phase On Aspects Of Exercise Physiology And Athletic Performance In Female Athletes: Protocol For The Feminae International Multisite Innovative Project, Kirsty J. Elliott Sale, Tessa R. Flood, Shawn M. Arent Ph.D., Cscs*D, Fissn, Facsm, Fnak, Eimear Dolan, Bryan Saunders, Mette Hansen, Johanna K. Ihalainen, Ritva S. Mikkonen, Clare Minahan, Jane S. Thornton, Kathryn E. Ackerman, Constance M. Lebrun, Craig Sale, Trent Stellingwerff, Paul A. Swinton, Anthony C. Hackney
Faculty Publications
The idiom € more high-quality research is needed' has become the slogan for sport and exercise physiology-based research in female athletes. However, in most instances, it is challenging to address this gap of high-quality research in elite female athletes at a single study site due to challenges in recruiting enough participants with numerous menstrual cycle and contraceptive pill permutations. Accordingly, we have assembled an international multisite team to undertake an innovative project for female athletes, which investigates the effects of changes in endogenous and exogenous oestrogen and progesterone/progestins across the menstrual cycle and in response to second-generation combined monophasic contraceptive …
Quantification Of The Internalization Of A Commercially Available Silver Nanoparticle To The Bacterium Escherichia Coli, Samantha Mcneal Case
Quantification Of The Internalization Of A Commercially Available Silver Nanoparticle To The Bacterium Escherichia Coli, Samantha Mcneal Case
Theses and Dissertations
Nanoparticles (NPs), materials with dimensions ranging from 1 to 100 nanometers, are widely used in various consumer products, with silver nanoparticles (AgNPs) being the most prominent. Exposure to AgNPs occurs through multiple sources, including food packaging, supplements, and disinfectants, owing to their antimicrobial properties. Prior research has identified adverse health effects, such as cytotoxicity, toxicity, and Ag bioaccumulation resulting from AgNP exposure to bacteria in biological systems and the environment. However, most studies employ pristine, highly concentrated NPs, which may not accurately represent realistic exposure scenarios at environmentally relevant concentrations. This project investigates the fate and internalization of AgNPs, found …
Infection Intensity And Prevalence From Perkinsus Marinus In The Eastern Oyster, Crassostrea Virginica (Gmelin 1791) And Their Association With Salinity, Temperature, And Sex In South Carolina Estuaries, Deja E. Best
Theses and Dissertations
This project aimed to identify the associations between the infection intensity and prevalence of Perkinsus marinus infection (i.e., Dermo ) in the Eastern oyster, Crassostrea virginica (Gmelin), with extrinsic environmental factors such as changes in salinity and temperature along with oyster host factors such as sex ratio. The objectives of the study were to: (1) identify significant associations between the dependent variables, P. marinus prevalence and infection intensity, in relation to salinity and water temperature which may be affected by climate change; and (2) identify any intrinsic factors related to sex (i.e., male, female, intersex, and indeterminant) that may affect …
Replenishment Of Essential Natural Resources: An Assessment Of The Ability Of Freshwater Algae To Enhance Crop Quality And Soil Health, Lala Christina Ek
Replenishment Of Essential Natural Resources: An Assessment Of The Ability Of Freshwater Algae To Enhance Crop Quality And Soil Health, Lala Christina Ek
Theses and Dissertations
Disregard for soil, an essential natural resource, hinders global food production. Food insecurity is a major concern for both public health officials and environmental scientists due to soil quality decline, pollution, and climate change. Alternatives or targeted additions to chemical fertilizers can bolster soil quality, improve crop yields, lengthen crop shelf life, and mitigate environmental pollution. One potential alternative to chemical fertilizers is replacement of them with biological soil amendments, including algae, to enhance crop growth and improve soil health. Research was conducted at the University of South Carolina-Columbia campus garden to determine impacts of non-toxic freshwater algae on crop …
Application Of Computational Tools To Identify Variations Associated With Peromyscus Dominant Spot, Zhenhua Shang
Application Of Computational Tools To Identify Variations Associated With Peromyscus Dominant Spot, Zhenhua Shang
Theses and Dissertations
Peromyscus are the most prevalent mammalian species in North America, and they're employed extensively in both laboratory and field studies. P. maniculatus and P. polionotus, the deer mouse and the old-field mouse, are closely related and can produce viable and fertile hybrid offspring. However, a comprehensive database of polymorphisms, particularly in those kept as living stocks and supplied to university researchers, is lacking. In chapter 2, we performed comparative genomic study on P. maniculatus and P. polionotus and used the polymorphic data to identify the range of genetic complexity that underlies physiological and behavioral differences between two species. We also …
Causes And Consequences Of The Risk Of Generalizability Biases In Health Behavioral Interventions, Lauren Von Klinggraeff
Causes And Consequences Of The Risk Of Generalizability Biases In Health Behavioral Interventions, Lauren Von Klinggraeff
Theses and Dissertations
Preliminary testing of health behavior interventions (e.g., pilot, feasibility studies) are used to evaluate intervention viability prior to additional testing and resource investment (e.g., larger trials). This initial testing provides valuable information, but promising estimates of effectiveness produced during early testing are rarely reproduced in larger studies, stalling the development of effective, scalable health interventions. In the obesity intervention literature, external validity biases, features of the intervention that are not (or cannot) transfer to the larger study, are associated with these diminished effects. These study features, such who delivers the intervention, the characteristics of the population receiving the intervention or …
The Effect Of Antibiotics On Immune Cell Infiltration Of Colon In A Mouse Model Of Early Onset Colorectal Cancer, Valerie Hinsch
The Effect Of Antibiotics On Immune Cell Infiltration Of Colon In A Mouse Model Of Early Onset Colorectal Cancer, Valerie Hinsch
Theses and Dissertations
Early onset colorectal cancer (EOCRC) is an aggressive form of colorectal cancer diagnosed before the age of 50. While colorectal cancer cases in patients 50 years and older have been declining, EOCRC cases have been steadily increasing globally in the last few decades, and the cause is unknown. Many agents, called exposomes, have been associated with EOCRC based on their emergence and prevalence prior to and in parallel with the rise in EOCRC cases. Among these are antibiotics (Abx). Abx are indispensable in our fight against infectious diseases, however their overuse is becoming a global epidemic. They are prescribed globally, …
From Oceans To Public Health: Impact Of Climate Change And Socioecological Factors On Non-Cholera Vibrio Spp., Karlen Enid Correa Vélez
From Oceans To Public Health: Impact Of Climate Change And Socioecological Factors On Non-Cholera Vibrio Spp., Karlen Enid Correa Vélez
Theses and Dissertations
Climate change-induced stressors, such as temperature, salinity, pH, and wildfire, are contributing factors to the increase in frequency of Vibrio infections, altering Vibrio geographical constraints. At the same time, the expansion of the coastal population is resulting in increased input of treated municipal wastewater into areas that are also experiencing Vibrio proliferation. Given that increases in ocean temperature and sea level coupled with increases in human activity in coastal waters support greater Vibrio-human interactions, it is important to examine factors and mechanisms within this socio-ecological coupled system that may further strengthen this interaction. This study aimed to better understand the …
Integrated Wastewater Surveillance For Sars-Cov-2 And Antibiotic Resistant Bacteria: Implications For Public Health And Environmental Management, Mirza Isanovic
Integrated Wastewater Surveillance For Sars-Cov-2 And Antibiotic Resistant Bacteria: Implications For Public Health And Environmental Management, Mirza Isanovic
Theses and Dissertations
While current technologies have inadvertently resulted in wastewater treatment plants (WWTPs) becoming major sources of global antibiotic resistance gene (ARG) dissemination, wastewater can be leveraged to provide vital community-level health information. This project examined both of these aspects through wastewater-based surveillance of SARS-CoV-2 and metagenomic analysis of specific ARGs collected from both activated sludge and bioaerosols. In this study, we investigated treatment steps between the influent and final treated effluent to identify the point at which viral RNA is below detection. Additionally, we examined air surrounding high turbulence treatment steps to test for the presence of SARS-CoV-2 RNA in WWTP-generated …
The Role Of Insulin Signaling In Controlling Oogenesis In Drosophila Melanogaster, Tancia W. Bradshaw
The Role Of Insulin Signaling In Controlling Oogenesis In Drosophila Melanogaster, Tancia W. Bradshaw
Theses and Dissertations
Adult stem cell activity responds to organismal nutrient status to maintain and support tissue homeostasis. Despite the intricate relationship between dietary input, adipose tissue and peripheral organ function, we are at the tip of the iceberg regarding our understanding of the cellular and molecular mechanisms underlying adipose communication to other tissues. The Drosophila ovary receives nutritional signals from the fat body with multiple nutrient-sensing pathways functioning in adipocytes to control distinct stages of oogenesis. Insulin/insulin-like growth factor signaling (IIS) within adult adipocytes remotely controls oocyte production at distinct stages of oogenesis. The PI3K/Akt1 axis in adipocytes promotes germline stem cell …
Transdisciplinary Approaches To Community Engagement, Research Translation And Science Communication Through Application Of The Socio-Environmental Report Card Process And Product In Murrells Inlet, South Carolina, Ekaterina Negodyaeva Altman
Transdisciplinary Approaches To Community Engagement, Research Translation And Science Communication Through Application Of The Socio-Environmental Report Card Process And Product In Murrells Inlet, South Carolina, Ekaterina Negodyaeva Altman
Theses and Dissertations
Public health and environmental sustainability are interlinked. Three pillars of sustainable development are society, environment, and economy are supported and reinforced by healthy populations. Balancing these values in a long-term vision and application requires active involvement of communities and stakeholders in decision-making process of management of environmental resources and personal health choices. Transdisciplinary sustainability science provides a framework for addressing complex issues in sustainability and generates actionable knowledge to link science and policy and involved stakeholders in the scientific process. Transdisciplinary research processes use co-design, co-production, and co-implementation framework to create and re-integrate useful knowledge into practice on a local …
Dephosphorylation Of Mpk6 And Mpk3 By Phosphatases Modulates Responses To Herbivory In Arabidopsis, Claire Teresa Hann
Dephosphorylation Of Mpk6 And Mpk3 By Phosphatases Modulates Responses To Herbivory In Arabidopsis, Claire Teresa Hann
Theses and Dissertations
As sessile organisms, plants rely on extracellular signals and chemical responses to defend against stressors. Extracellular stress signals inducing defense responses originate both from biotic or abiotic threats, and from products of tissue damage or hormones. In defense against herbivores, essential responses include rapid generation of jasmonic acid (JA) at the wound site, followed by the global expression of genes that impede digestion and growth. Early defense gene expression amplifies JA production, while later JA-responsive gene expression causes the accumulation of defense products. MAP kinase (MAPK) pathways play a central role in mediating the perception of self, non-self, and hormonal …
Video Based Estimation Of Surface Currents In A Tidal Inlet, Benjamin Middour, George Voulgaris, Douglas Cahl
Video Based Estimation Of Surface Currents In A Tidal Inlet, Benjamin Middour, George Voulgaris, Douglas Cahl
Faculty Publications
Oceanic surface currents are estimated from analysis of short duration video obtained by a nadir facing camera installed on a bridge over a tidal inlet. Data analyzed consisted of 13 two-minute video clips captured approximately every 40 min over a period of 8 hr, covering a significant portion of the tidal cycle. Surface current speed and direction estimates are obtained from each collected video using (i) a method originally developed for analysis of imagery from drones (CopterCurrents) and (ii) a particle tracking method. The horizontal (u, v) surface current velocity components and total horizontal velocity magnitude, obtained from the two …
Environmental Bacteriophage Presence In Drainage Ponds At Coastal Carolina University, Hailey Oldfield, Alexei E. Chesnutwood, Gabriella A. Caldwell, Shiraz C. Cohen, Paul E. Richardson
Environmental Bacteriophage Presence In Drainage Ponds At Coastal Carolina University, Hailey Oldfield, Alexei E. Chesnutwood, Gabriella A. Caldwell, Shiraz C. Cohen, Paul E. Richardson
Journal of the South Carolina Academy of Science
No abstract provided.
Developing A Safe And Effective Papillomavirus Screen To Be Used On College Students At A South Carolina University, Owen R. Smith, Nicole E. Frantz, Emily E. Bishop, Rahjai G. Thomas, Paul E. Richardson
Developing A Safe And Effective Papillomavirus Screen To Be Used On College Students At A South Carolina University, Owen R. Smith, Nicole E. Frantz, Emily E. Bishop, Rahjai G. Thomas, Paul E. Richardson
Journal of the South Carolina Academy of Science
No abstract provided.
Table Of Contents
Journal of the South Carolina Academy of Science
No abstract provided.
Identification Of A Small Regulatory Rna Usps Associated With The Universal Stress Protein In Lactobacillus Species, Zarah M. Fowler, Sasha S. Bronovitskiy, Finn K. Rose, Brian M. Lee
Identification Of A Small Regulatory Rna Usps Associated With The Universal Stress Protein In Lactobacillus Species, Zarah M. Fowler, Sasha S. Bronovitskiy, Finn K. Rose, Brian M. Lee
Journal of the South Carolina Academy of Science
The gut microbiome is a complex habitat with many bacterial species, each playing crucial roles in regulating various physiological processes in the body. As the use of probiotics to combat human disease continues to increase, it is important to understand the mechanisms by which probiotic bacteria regulate their interactions with other bacteria and their host. Our exploration of the physiological functions of probiotic bacteria hopes to elucidate the role of small regulatory RNA (sRNA) in regulating gene expression within the microbiome. The goal of this project was to characterize the structure and function of the sRNA, UspS, which is found …
The Sound Of Geological Targets On Mars From The Absolute Intensity Of Laser-Induced Sparks Shock Waves, C. Alvarez-Llamas, J. Laserna, J. Moros, P. Purohit, L. García-Gómez, S. M. Angel Ph.D., P. Bernardi, B. Bousquet, A. Cadu, E. Dauson, O. Forni, T. Fouchet, O. Gasnault, X. Jacob, G. Lacombe, N. L. Lanza, C. Larmat, J. Lasue, R. D. Lorenz, P. Y. Meslin, D. Mimoun, F. Montmessin, N. Murdoch, A. M. Ollila, P. Pilleri, N. Randazzo, A. L. Reyes-Newell, S. Schröder, A. Stott, J. Ten Cate, A. Udry, D. Vogt
The Sound Of Geological Targets On Mars From The Absolute Intensity Of Laser-Induced Sparks Shock Waves, C. Alvarez-Llamas, J. Laserna, J. Moros, P. Purohit, L. García-Gómez, S. M. Angel Ph.D., P. Bernardi, B. Bousquet, A. Cadu, E. Dauson, O. Forni, T. Fouchet, O. Gasnault, X. Jacob, G. Lacombe, N. L. Lanza, C. Larmat, J. Lasue, R. D. Lorenz, P. Y. Meslin, D. Mimoun, F. Montmessin, N. Murdoch, A. M. Ollila, P. Pilleri, N. Randazzo, A. L. Reyes-Newell, S. Schröder, A. Stott, J. Ten Cate, A. Udry, D. Vogt
Faculty Publications
Inspection of geological material is one of the main goals of the Perseverance rover during its journey across the landscape of the Jezero crater in Mars. NASA's rover integrates SuperCam, an instrument capable of performing standoff characterization of samples using a variety of techniques. Among those tools, SuperCam can perform laser-induced breakdown spectroscopy (LIBS) studies to elucidate the chemical composition of the targets of interest. Data from optical spectroscopy can be supplemented by simultaneously-produced laser-produced plasma acoustics in order to expand the information acquired from the probed rocks thanks to the SuperCam's microphone (MIC) as it can be synchronized with …
Sleep, Physical Activity, And Sedentary Time In The First Year Postpartum, Erin Elizabeth Kishman
Sleep, Physical Activity, And Sedentary Time In The First Year Postpartum, Erin Elizabeth Kishman
Theses and Dissertations
The postpartum period is a unique time for women, where many women experience changes in sleep and activity patterns. Sleep, physical activity, and sedentary time have all been associated with health outcomes, but there is limited research on how these behaviors change throughout the postpartum period. The purpose of the first aim (Study 1) of this dissertation was to examine trajectories of sleep characteristics in Black and White women during the first year postpartum and to examine if there were any racial differences. The purpose of the second aim (Study 2) was to examine trajectories of the percentage of time …
Mechanisms Of Social Stress Susceptibility And Resilience In Female Rats, Brittany Sara Pate
Mechanisms Of Social Stress Susceptibility And Resilience In Female Rats, Brittany Sara Pate
Theses and Dissertations
Social stress is the most common form of stress humans experience and often precipitates the onset of several comorbidities, including anxiety, depression, post-traumatic stress disorder, and cardiovascular diseases. While many individuals experience social stress and can respond, cope, and recover, some individuals are more likely to develop subsequent health conditions. Importantly, women are particularly susceptible to stress-related disorders, and the prevalence rates for these comorbid conditions are 2-3-fold higher among females compared to males. Epidemiological data suggest that cycling ovarian hormones may play a role in promoting stress susceptibility in females. Therefore, the current studies aimed to examine the effects …
Long-Chain Fatty Acid Sensing And Catabolism In Commensal Escherichia Coli Impact Murine Gut Colonization, Tessa Carolina Cox
Long-Chain Fatty Acid Sensing And Catabolism In Commensal Escherichia Coli Impact Murine Gut Colonization, Tessa Carolina Cox
Theses and Dissertations
The gastrointestinal tract is home to trillions of microbes that collectively influence host physiology, immunity, nutrient metabolism, and infectious disease. The overgrowth of naturally-occurring Escherichia coli in the gut is a common signifier of microbiome dysfunction and occurs in many chronic diseases including obesity. Recent studies have shown that higher fat intake is associated with increased gut E. coli growth. However, it remains unknown whether gut E. coli utilize lipids such as long chain fatty acids (LCFAs) as carbon sources to colonize the mammalian gut. Therefore, the central objective of my dissertation was to utilize bacterial genetics and various mouse …
The Impact Of Progerin On Genome Maintenance In Mammalian Cells, Liza Alexandra Joudeh
The Impact Of Progerin On Genome Maintenance In Mammalian Cells, Liza Alexandra Joudeh
Theses and Dissertations
Hutchinson-Gilford Progeria Syndrome (HGPS) is a rare genetic condition characterized by accelerated aging. The cause of HGPS is a point mutation in the LMNA gene, which encodes lamins A and the splice variant lamin C. Lamins are components of the nuclear lamina, a complex that plays structural and catalytic roles in the nucleus that are essential to chromatin organization, DNA replication, and DNA repair. The mutation associated with HGPS activates a cryptic splice donor site which alters the lamin A protein in a way that does not allow prelamin A to be fully processed, and ultimately results in the accumulation …