Life Sciences Commons^™

Associations Between Food Insecurity And Gpa Among Full-Time California State University Undergraduates During Covid-19: The Impact Of Mental Health, Lindsey Jones

Master's Theses

Food insecurity is a persistent public health concern among college students that has been associated with student’s academic and mental health outcomes. This thesis examined the associations between food insecurity, academic performance (measured by GPA) and mental health (using Kessler 6 psychological distress and self-perceived mental health impacts on academic performance), among full-time undergraduate students within the California State University (CSU) system. Cross-sectional analyses were conducted using data from the Spring 2021 CSU National College Health Assessment, administered across all 23 campuses. Of the 20,167 respondents, 12,899 students were included in the analytical sample. Bivariate analyses were conducted to analyze …

Why The Long Face? The Distribution And Niche Of The Imperiled Narrow-Faced Kangaroo Rat (Dipodomys Venustus), Garrett L. Gimbel

Master's Theses

Distribution models provide a practical use case of connecting ecological niche theory with species’ occurrence and assemblages. By explicitly linking Hutchinson’s “niche space” with geographic space researchers can gain valuable information on a species’ niche characteristics and interactions, thereby informing conservation and management practices. The narrow-faced kangaroo rat (Dipodomys venustus) is a highly understudied kangaroo rat species endemic to the central coast of California and is an ideal species to explore niche theory in distribution modeling. Three subspecies are currently recognized: The Santa Cruz kangaroo rat (D. v. venustus), the elephant-eared kangaroo rat (D. v. …

Serum Concentrations Of Inflammatory Markers And Selected Nutrient Metabolites In Holstein And Jersey Cows Across The Transition Period, Avery Orr

Master's Theses

The transition period, spanning the weeks surrounding parturition, requires dairy cows to undergo synchronized metabolic, endocrine, and immunological adjustments that support the onset of lactation but also heighten disease susceptibility. Although individual inflammatory or metabolic biomarkers have been extensively studied, the integrated immunometabolic dynamics that occur across this period and the difference between breeds is not fully understood. The objective of this study was to characterize longitudinal patterns in key nutrient metabolites and inflammatory markers in Holstein and Jersey cows and assess how these systems interact across the transition period.

A total of 63 Holstein and Jersey cows were sampled …

Testing For Local Adaptation In Sympatric Monkeyflowers Growing In Serpentine Seeps And Adjacent Rock Outcrops, Avin Niknafs

Master's Theses

Divergent selection across heterogeneous environments can drive ecological differentiation and the evolution of locally adapted populations, even when gene flow occurs. We tested for local adaptation between two sympatric monkeyflowers, Erythranthe guttata and E. serpentinicola (formerly Mimulus), which co-occur on the central coast of California. Erythranthe guttata is a perennial species primarily found in moist serpentine seeps, whereas E. serpentinicola is an annual species restricted to adjacent serpentine rock outcrops. Using a reciprocal transplant experiment with second-generation, greenhouse-derived seed, we quantified germination, survival, and reproductive success across contrasting microhabitats. We further evaluated the relative contributions of species, lineage, …

Establishing Procedures For Primary Human Myoblast Cell Culture, Erica Duffy

Biomedical Engineering

Peripheral Artery Disease (PAD) affects an estimated 200 million people worldwide and is the leading cause of amputation in the United States. PAD is characterized by atherosclerotic narrowing of arteries, resulting in ischemia from reduced blood flow to distal tissues. Although surgical and percutaneous interventions can restore perfusion, fewer than 50% of patients experience sustained benefit, highlighting the need for alternative therapeutic strategies. One promising approach is promoting arteriogenesis, the growth and outward remodeling of pre-existing collateral vessels that improve blood flow around the occluded arteries. Arteriogenesis is regulated by regenerative, M2-polarized macrophages, making macrophage polarization a key therapeutic target. …

Dietary Intake And Changes In Body Composition Over The Course Of One Season In Ncaa Division 1 Football Players, Blayke W. Harrison

Master's Theses

Energy intake and macronutrient composition of an athlete’s diet is highly important when considering performance. Additionally, having a favorable body composition (i.e. low levels of fat mass and high levels of lean body mass) is crucial in high-level athletes.The role of nutrition-related support personnel is highly needed by many collegiate athletics programs to achieve these outcomes, yet this resource seems to be undervalued and underused in many settings. The present thesis investigates the effects of providing nutritional support to improve dietary habits and compare changes in specific body composition metrics over the course of one season (pre- and post-season) among …

Gene Expression Of Anthocyanin Pigments In The California Native Plant Leptosiphon Parviflorus: Interactions Between Flower Color Morphology And Abiotic Stressors, Weston Gonor

Master's Theses

For plants to survive in harsh conditions imposed by abiotic stressors, they must develop mechanisms of adaptation. One of the common types of adaptation seen in plants is the production of anthocyanin pigments, which have been shown to protect plants from UV radiation, metabolic stress, and drought. In this study, we used the flower color polymorphic species Leptosiphon parviflorus to investigate the role of anthocyanin pigments in protecting plants from abiotic stress. To accomplish this, RNA samples were taken from flower, leaf and root tissue of different flower color morphs of Leptosiphon parviflorus (Polemoniaceae) grown in high magnesium and water …

Alpine Plants And Climate Change: Tracking Community Shifts In Yosemite National, Brooke L. Wallasch

Master's Theses

As climate change progresses, alpine plant communities are predicted to shift upslope as they track temperature over time. Relative to lowland environments, alpine areas are experiencing a faster rate of temperature change due to a phenomenon referred to as elevation-dependent warming. A common approach for tracking plant communities shifts over time, is to conduct resurveys of the same area at several time points, as the Global Observational Research Initiative in Alpine Environments (GLORIA) has done on mountain summits around the world since 2001. In 2011-2013, GLORIA developed a supplemental survey method whereby belt transects were established downslope of summits in …

Enhancing Preparedness: A Genetic Study Of Sar-Cov-2 And Other Microbial Public Health Threats In Wastewater From A College Town, Christian N. Hutchinson

Master's Theses

Problem

The SARS-CoV-2 (COVID-19) pandemic revealed both the systemic vulnerabilities of our healthcare system as well as the importance of timely, localized data for informing public health responses. Traditional testing approaches were essential but often failed to capture the full extent of viral spread, especially in those with mild or asymptomatic conditions that relied on at home testing. This underreporting hindered effective allocation of resources and made developing effective intervention strategies difficult. We also realized the potential for wastewater surveillance to be applied to tracking antimicrobial resistance gene markers. Taken together, this approach should have important implications for improving public …

Owl Integrations Soil Monitor, Derek Chau, Armaan Kahlon

Electrical Engineering

This paper examines the design process and results concerning the OWL Integrations soil monitor. Disaster relief relies heavily on digital communications, especially in environments where conventional methods (e.g. Wi-Fi, cellular, fiber optics) are unusable. To help emergency services assess disaster-stricken areas, a soil monitoring system was developed using LilyGo T-Beams (ESP32), programmed with specialized firmware known as the ClusterDuck Protocol to collect data pertaining to moisture and temperature. The project is sponsored by OWL Integrations, with help from the Cal Poly Electrical Engineering (EE) Department. Results show positive prospects, with the product able to make 4 km transmissions, operate for …

Coyote (Canis Latrans) And Non-Target Wildlife Responses To Livestock Guardian Dogs At Sheep Grazing Sites On The California Central Coast, Tricia T. Nguyen

Master's Theses

Livestock depredation is one of the oldest and most widespread forms of human-wildlife conflict. The coyote (Canis latrans), a midsized canid, represents a significant proportion of domestic sheep depredations in the United States, costing livestock producers an estimated 24.6 million dollars annually. Management strategies for coyote-sheep depredation vary widely in their effectiveness and in their level of public support. Identifying appropriate strategies for farms, ranches, and other sheep grazing sites remains a pressing need due to the potentially negative consequences for surrounding ecosystems and socioeconomic outcomes for sheep producers. The livestock guardian dog (LGD) is a nonlethal control …

Using Livestreaming Technology To Answer Novel Questions About The Behavior And Physiological Ecology Of The Prairie Rattlesnake (Crotalus Viridis), Max C. Roberts

Master's Theses

Recent advances in remote monitoring technology are opening up new opportunities for developing innovative natural history and biological research methodologies. In particular, the emergence of livestreaming camera technology has made recording remote video of wild and secretive animals much easier and made it possible to collect data at extremely fine temporal resolutions. In 2024, Project RattleCam launched a livestreaming camera at a Prairie Rattlesnake (Crotalus viridis) den in Colorado. The goal of this work was to study Prairie Rattlesnake behavior 24-7 throughout the species’ active season with minimal human disturbance. Additionally, I used this system to study the …

Investigating Rattlesnake Social Networks And Improving Their Public Image Through Unobtrusive Technologies And Community Science, Owen M. Bachhuber

Master's Theses

While technology is often blamed for humans’ increasing disconnect with nature, it can also serve as a tool to facilitate empathy and conservation action for wildlife. Snakes are among the most feared animals on the planet, though their understudied social interactions provide opportunities to make scientific discoveries and change public perceptions. Project RattleCam was founded as a camera trap project in 2021 and launched the first off-grid livestream on a den of wild Prairie Rattlesnakes (Crotalus viridis) in 2024. Both camera types captured hundreds of Prairie Rattlesnakes gathering in the summer as they prepared to give birth to pups before …

Smart Glove Pitch Type Discrepancy Detection Algorithm For Youth And Collegiate Baseball Pitchers, Ethan B. Hemmerlin

Master's Theses

Pitch tipping refers to unintentional variations in a pitcher’s motion that reveal the pitch type, often due to inconsistent arm speed when throwing off-speed pitches like changeups. This issue is common in youth players with underdeveloped mechanics and makes it easier for batters to predict pitches. Wearable sensors, such as Inertial Measurement Units (IMUs), provide a non-invasive way to quantify these subtle motion discrepancies. This study analyzed linear acceleration data from a glove arm IMU for 14 pitchers, evenly split between high school-aged (13-15 years) and college-aged (18-23 years) groups. The aim was to examine the linear accelerations of the …

Effects Of Spirulina And Nannochloropsis Supplementations On The Meat Quality And Sensory Properties Of Broiler Carcasses, Shreyash S. Patel

Master's Theses

Microalgae are a promising feed ingredient due to their high content of proteins, lipids, polysaccharides, vitamins, pigments, and enzymes. This study evaluated the effects of algae as a dietary supplementation on the appearance, quality, and sensory attributes of broiler carcasses. In each of experiment I and II, a total of 54 Ross-708 broilers were randomly obtained from the pool of 270 broilers in the 18 floor pens of soybean-mealbased diets at 0, 2.5%, and 5% Spirulina (Experiment I) and Nannochloropsis (Experiment II) supplements in the Poultry Unit at California Polytechnic State University (Cal Poly, San Luis Obispo, CA). Broiler carcasses …

Understanding The Habitat Associations Of Nearshore Rockfishes Inside And Outside Of Marine Protected Areas Using Hook-And-Line Data, Kaila Raeanne Fritch

Master's Theses

Habitat is an important driver in shaping the distribution of a range of species. For demersal fish species, benthic habitat characteristics can drive distribution and community structure. Understanding the relationship between habitat and species distribution in important, especially for exploited species such as rockfishes (Sebastes spp.). Increased data on the relationship between rockfish and benthic habitat characteristics could enhance marine protected areas (MPAs) and management practices which are used to protect rockfishes along the U.S. West Coast. To address this, we used hook-and-line, catch-and-release data that were collected inside two MPAs on the central coast of California, and …

The Effect Of Whole Fruits High In Anthocyanins On Markers Of Glycemic Control In Women, Sophia C. Johnson

Master's Theses

Cardiometabolic diseases are a significant health burden worldwide and remain the leading cause of death among adults in the United States. Type 2 diabetes mellitus (T2DM) is a central component of cardiometabolic dysfunction and substantially increases the risk for cardiovascular disease. As women enter the post-menopausal period, significant declines in estrogen levels lead to a heightened risk of T2DM in this population. Observational and experimental evidence has shown potential for fruits high in anthocyanins (ACs) to reduce the risk of T2DM and improve glycemic control. This systematic review and meta-analysis examined the current research on whole fruits high in ACs …

Subalpine And Alpine Plant Community Turnover In Yosemite National Park Following 30 Years Of Climate Warming, Rachel Friesen

Master's Theses

Subalpine and alpine regions in California are warming more rapidly than lower elevations. In response, high-elevation plants may acclimate or adapt to the new climate, move to higher elevations or latitudes, persist in refugia, or go extinct. While models predict substantial declines in subalpine and alpine plant communities due to discontinuous population distributions and lack of upslope area, actual responses may vary due to lags in dispersal, establishment, and extinction. Although shifts in high-elevation plant communities have been documented in other regions of the world, such changes have not yet been studied in Yosemite National Park. To assess high-elevation plant …

When Trees Disappear: Understory Successional Implications Of Sudden Oak Death And High-Severity Wildfire In Big Sur, California, Sam J. Balthazard

Master's Theses

The rapidly emerging disease sudden oak death, caused by the non-native pathogen Phytophthora ramorum, is transforming coastal California forests by driving extensive mortality of tanoak (Notholithocarpus densiflorus) and increasing fire severity. As a novel disturbance, sudden oak death and its interaction with wildfire may catalyze unexpected shifts in successional trajectories and reconfigure forest understory communities. Furthermore, how tanoak influences the forest understory and how its decline might reshape understory dynamics remain poorly understood. We hypothesize that disease alone and the compounding disturbances of disease and wildfire alter successional dynamics, and that the potential functional extinction of N. …

Topodino: Self-Supervised Topological Representation Learning For Neuronal Morphologies, Yasser Binbisher

Master's Theses

Neuronal cell types are categorized by transcriptomic identity, yet their morphological heterogeneity defies this classification. In response, researchers have adopted unsupervised graph representation learning as a tool to reveal morphological variation within single-class transcriptomic types. However, the complex geometry of neuronal morphology—especially long axons and dense dendrites—challenges graph neural networks, which struggle with message propagation across extended structures. To mitigate this, current approaches enforce sub-sampling on neuronal graphs and omit axons entirely, sacrificing critical biological features for computational efficiency. To overcome this trade-off, this thesis introduces TopoDINO, a self-supervised, topology-aware representation learning model designed to preserve the full hierarchical organization …

"The Effect Of Methylobacterium Symbioticum On The Growth And Yield Of Dent Corn And Romaine Lettuce", Sinead Carney

Master's Theses

Nitrogen (N) is an essential nutrient for plant growth and is often a limiting nutrient in cropping systems. An estimated half of applied N fertilizers are lost from cropping systems by processes that can be environmentally destructive, such as leaching and volatilization, and cause economic loss for growers. Effective N biofertilizers offer a means to mitigate the need for high inputs of synthetic N. The objectives of this study were to determine the effects of leaf inoculation with the N-fixing bacteria, Methylobacterium symbioticum, in combination with different rates of urea-N fertilizer on the physiology and yield of dent corn …

Stability Insights From Modeling Chronic Myelogenous Leukemia, Giovani Thai

Master's Theses

This thesis centers around a model for chronic myelogenous leukemia (CML) as it behaves under imatinib treatment, a common medication for CML patients, and the anti-leukemia immune response. The dynamics are represented with a system of nonlinear delay-differential equations first constructed by Kim et al. in 2008, capturing population changes of T-cells and various CML growth stages. We investigate stability in both the clinical and mathematical sense. Through numerical simulations, we computationally incorporate a supplementary treatment plan to determine its effectiveness in aiding immune response and medication in achieving remission and full elimination. The primary goal is to conduct a …

Optimization Of Downy Mildew Management And Baby Kale Production On The Central Coast Of California, Emily M. Locke-Paddon

Master's Theses

Baby kale (Brassica oleracea and other species) is a vital commodity as a salad green in spring mix and is widely produced on the Central Coast of California. Downy mildew, caused by Hyaloperonospora brassicae, is a devastating disease infecting economically important crops like cabbage, broccoli, cauliflower, horseradish, rapeseed, kohlrabi, Brussels sprouts, and kale. This foliar disease causes plant tissue to exhibit chlorotic and necrotic flecking and gray-white sporulation, affecting both the yield and quality of the crop and rendering the affected leaves unmarketable. The Central Coast’s cool climate and nighttime moisture, combined with dense plantings and sprinkler irrigation, …

Identifying Interchromosomal Interactions Using A Graph-Based Computational Pipeline, Ethan Outangoun

Master's Theses

Current computational tools for analyzing chromatin organization are mainly focused on intrachromosomal interactions, despite growing evidence that suggests long-range interactions across chromosomes contribute to transcriptional regulation and disease development. This thesis aims to address this gap in interchromosomal genome analysis, presenting a robust computational pipeline that identifies a clique (i.e., a subgraph) of highly interacting trans-chromosomal regions anchored at a user-specified seed genomic locus. A weighted interaction network is constructed from an input Hi-C contact matrix, a widely used experimental assay for measuring genome-wide chromatin interactions. We model this input contact matrix as a graph and devise three different strategies …

Correlations Between Social Media, Body Image Perceptions, And Disordered Eating Prevalence In Postpartum Women: A Pilot Cross-Sectional Study, Hannah Smith

Master's Theses

Postpartum women are a high-risk population for body dissatisfaction and disordered eating behavior due in part to the plethora of hormonal and physiological changes. Despite this, research examining this issue among postpartum women remains limited.

This pilot cross-sectional study investigated the relationship between social media use, body dissatisfaction, and disordered eating behavior among women up to 13 months postpartum. For this study, the following research questions were asked: Is high social media usage associated with higher levels of disordered eating among women up to 13 months postpartum? Is the association between social media usage and disordered eating mediated by a …

Evaluating Nanobubble-Enriched Water Treatments For Cleaning Stainless Steel Winery Tanks At The Gallo Winery Research Station In Livingston, California, Edgar Godoy-Garcia

Master's Theses

ABSTRACT

Evaluating nanobubble-enriched water treatments for cleaning stainless steel winery tanks at the Gallo winery research station in Livingston, California.

Edgar A. Godoy-Garcia

Sanitation of stainless steel wine storage tanks is a critical component of quality control in commercial winemaking operations. Ineffective cleaning can lead to microbial contamination, product spoilage, and safety concerns. Traditionally, wineries rely on manual scrubbing, chemical cleaning agents, and extensive water rinsing cycles to maintain sanitary tank conditions. However, these methods are resource-intensive and may pose risks to both workers and the environment due to chemical exposure and wastewater generation. In response to growing industry interest …

The Effects Of Sirulina And Nannochloropsis Supplementation On Broiler Performance, Intestinal Morphology, And Gut Microbiology, Emily Beckerman

Master's Theses

The poultry industry is constantly searching for new nutritional strategies and better feed conversion ratio to enhance broiler growth and productivity. Microalgae have been shown to improve broiler performance and health depending on species and supplementation levels. The objective of this study was to determine the effects of Spirulina supplementation (Experiment I) and Nannochloropsis supplementation (Experiment II) on broiler production performance, intestinal morphology, and gut microbiology. In Experiment I, a total of 270 broiler chicks (one-day-old Ross 708) were obtained from a local hatchery after vaccinating against Newcastle, Marek’s disease, and Infectious Bronchitis. They were weighed and sorted into 18 …

Impacts Of Temperature Acclimation On Swimming Performance And Metabolic Dynamics Of The Amargosa River Pupfish, Cyprinodon Nevadensis Amargosae, Teresa E. Guerre

Master's Theses

Climate change is leading to warmer atmospheric temperatures in many regions of the world, which in turn is raising the temperatures of aquatic habitats and simultaneously shifting the frequency and severity of extreme precipitation events. In fishes, metabolic demands are higher under warmer conditions, while dissolved oxygen levels typically decline in warmer water. This mismatch may limit the ability of fishes to cope with high water flow events like floods that can occur following extreme rainfall. A few species of pupfishes (genus Cyprinodon) in the Death Valley region of California and Nevada, USA, occupy stream or river habitats with …

Improved Management Strategies For Botrytis Fruit Rot, Macrophomina Root Rot, And Verticillium Wilt In California Strawberry Production, Joseph A. Ramirez

Master's Theses

Strawberry production in California is limited by plant diseases such as Macrophomina root rot (MRR) caused by Macrophomina phaseolina, Verticillium wilt (VW) caused by Verticillium dahliae, and Botrytis fruit rot (BFR) caused by Botrytis cinerea. Current disease management strategies are compromised due to fumigant regulations or ineffective disease management practices. This thesis investigated methods to potentially improve the management of these three diseases. Two host plant resistance evaluations for MRR and VW were conducted for the 2022-2023 and 2023-2024 growing seasons. Sixty-three strawberry genotypes were screened in both years. All plants were exposed to the pathogen via artificial …

Investigating The Effects Of Hepatocyte Growth Factor On Primary Myoblast Proliferation, Grace Heller

Biomedical Engineering

Peripheral artery occlusive disease (PAOD) is a progressive vascular condition that affects over 200 million people worldwide and approximately 8 million in the United States. It is characterized by atherosclerotic narrowing of peripheral arteries, leading to reduced blood flow, ischemia, and, in severe cases, tissue loss and limb amputation. Although surgical revascularization is the gold standard, many patients—particularly those with comorbidities like diabetes— continue to experience poor outcomes, emphasizing the need for alternative therapies. One promising strategy is to enhance collateral arteriogenesis, the remodeling and enlargement of collateral arterioles that naturally bypass occluded vessels. Satellite cells (SCs), which give rise …