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Articles 31 - 37 of 37

Full-Text Articles in Nanoscience and Nanotechnology

Studies Of Functionalized Nanoparticles For Smart Self-Assembly And As Controlled Drug Delivery, Xiaochu Ding Jan 2013

Studies Of Functionalized Nanoparticles For Smart Self-Assembly And As Controlled Drug Delivery, Xiaochu Ding

Dissertations, Master's Theses and Master's Reports - Open

This dissertation is related to the studies of functionalized nanoparticles for self-assembly and as controlled drug delivery system. The whole topic is composed of two parts. In the first part, the research was conducted to design and synthesize a new type of ionic peptide-functionalized copolymer conjugates for self-assembly into nanoparticle fibers and 3D scaffolds with the ability of multi-drug loading and governing the release rate of each drug for tissue engineering. The self-assembly study confirmed that such peptide-functionalized amphiphilic copolymers underwent different self-assembly behavior. The bigger nanoparticles were more easily assembled into nanoparticle fibers and 3D scaffolds with larger pore …


Probing And Controlling Fluid Rheology At Microscale With Magnetic Nanorods, Alexander Tokarev Aug 2012

Probing And Controlling Fluid Rheology At Microscale With Magnetic Nanorods, Alexander Tokarev

All Dissertations

This Dissertation is focused on the development of new methods for characterization and control of fluid rheology using magnetic nanorods. This Dissertation consists of five chapters. In the first chapter, we review current microrheologial methods and develop a Magnetic Rotational Spectroscopy (MRS) model describing nanorod response to a rotating magnetic field. Using numerical modeling, we analyze the effects of materials parameters of nanorods and fluids on the MRS characteristic features. The model is designed for a specific experimental protocol. We introduce and examine physical parameters which can be measured experimentally. The model allows identification of MRS features enabling the calculation …


Structural Basis Of Substrate Recognition In Thimet Oligopeptidase And Development Of Nanoparticles For Therapeutic Enzyme Delivery, Jonathan Mark Wagner Jan 2012

Structural Basis Of Substrate Recognition In Thimet Oligopeptidase And Development Of Nanoparticles For Therapeutic Enzyme Delivery, Jonathan Mark Wagner

Theses and Dissertations--Molecular and Cellular Biochemistry

Neuropeptidases are responsible for degradation of signaling peptides in the central nervous system and periphery. Some neuropeptidases have also been shown to play a role as part of the cell’s hydrolytic machinery responsible for breaking down proteins and peptides into amino acids, and these enzymes therefore influence small peptide availability for antigen presentation. A better understanding of how neuropeptidases recognize their substrates could lead to therapeutics that modulate the activity of these important enzymes. Alternatively, re-engineering these enzymes to selectively hydrolyze undesirable peptides could make them attractive as therapeutics themselves. A key question in understanding the activity of these enzymes …


Growth And Characterization Of Functional Nanoparticulate Films By A Microwave Plasma-Assisted Spray Deposition Process, Ted Wangensteen Jan 2012

Growth And Characterization Of Functional Nanoparticulate Films By A Microwave Plasma-Assisted Spray Deposition Process, Ted Wangensteen

USF Tampa Graduate Theses and Dissertations

Nanoparticle and nanoparticulate films have been grown by a unique approach combining a microwave and nebulized droplets where the concentration and thus the resulting particle size can be controlled. The goal of such a scalable approach was to achieve it with the least number of steps, and without using expensive high purity chemicals or the precautions necessary to work with such chemicals. This approach was developed as a result of first using a laser unsuccessfully to achieve the desired films and particles. Some problems with the laser approach for growing desired films were solved by substituting the higher energy microwave …


Synthesis, Stabilization, And Characterization Of Metal Nanoparticles, Gregory White Ii Dec 2010

Synthesis, Stabilization, And Characterization Of Metal Nanoparticles, Gregory White Ii

All Dissertations

Wet chemical synthesis techniques offer the ability to control various nanoparticle characteristics including size, shape, dispersibility in both aqueous and organic solvents, and tailored surface chemistries appropriate for different applications. Large quantities of stabilizing ligands or surfactants are often required during synthesis to achieve these nanoparticle characteristics. Unfortunately, excess reaction byproducts, surfactants, and ligands remaining in solution after nanoparticle synthesis can impede application, and therefore post-synthesis purification must be employed. A liquid-liquid solvent/anti-solvent pair (typically ethanol/toluene or ethanol/hexane for gold nanoparticles, GNPs) can be used to both purify and size-selectively fractionate hydrophobically modified nanoparticles. Alternatively, carbon dioxide may be used …


Electrocatalytic Oxidation Of Methanol At The Nano Ni-B Amorphous Alloy Powdermicroelectrode, Yi-Xiong Zheng, Shi-Bing Yao, Shao-Min Zhou Aug 2007

Electrocatalytic Oxidation Of Methanol At The Nano Ni-B Amorphous Alloy Powdermicroelectrode, Yi-Xiong Zheng, Shi-Bing Yao, Shao-Min Zhou

Journal of Electrochemistry

Electrocatalytic oxidation of methanol at the nano Ni-B amorphous alloy powder-microelectrode in alkaline media was studied by using cyclic voltammetry.Compared to the highly preferred orientation(220) nickel electrode,The onset potential of methanol electrooxidation at the nano Ni-B microelectrode is negatively shifted about 0.04V,and the current density is increased approximately by 2 orders of magnitude.Thus,the nano Ni-B microelectrode has very strong electrocatalytic activity for the oxidation of methanol.The kinetic parameters were determined with the steady polarization curves.The results show that the rate constants for both the oxidation of Ni(Ⅱ) to Ni(Ⅲ) and the reduction of Ni(Ⅲ) to Ni(Ⅱ) at the nano Ni-B …


Novel Electrochemical Method For Synthesis Of Nanostructured Materials Of Noble Metals Based On Poly(N-Vinylpyrrolidone) (Pvp), Wei Pan, Xiao-Kai Zhang, Ming-Hu Huang, Shao-Xin Huang, Xing-Li Feng, Hou-Yi Ma Nov 2006

Novel Electrochemical Method For Synthesis Of Nanostructured Materials Of Noble Metals Based On Poly(N-Vinylpyrrolidone) (Pvp), Wei Pan, Xiao-Kai Zhang, Ming-Hu Huang, Shao-Xin Huang, Xing-Li Feng, Hou-Yi Ma

Journal of Electrochemistry

Gold nanocrystals with controllable size were synthesized through a simple electroreduction method using poly(N-vinylpyrrolidone)(PVP) of different polymerization degree as both stabilizer and shape-controller for gold nanoclusters.Individual gold nanoparticles spontaneously assembled into the wire-and ring-shaped nanoparticle aggregates depending on the PVP's dynamic stretching and curling,and precursor nanoparticles grew into flat,single-crystalline nanoprisms with thickness of dozens of nanometers based on the oriented aggregation between particles.Besides,core-shell Au/Ag nanoparticles were conveniently synthesized through two-step electroreduction of noble metal ions in the presence of PVPK30.The electrochemical synthetic method based on PVP provides a new path for preparation of noble metal nanostructured materials with different shape …