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Master's Theses

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Articles 31 - 34 of 34

Full-Text Articles in Biomechanical Engineering

Poroelastic Finite Element Analysis Of A Heterogeneous Articular Cartilage Explant Under Dynamic Compression In Abaqus, Kelsey Kiyo Kam Jun 2011

Poroelastic Finite Element Analysis Of A Heterogeneous Articular Cartilage Explant Under Dynamic Compression In Abaqus, Kelsey Kiyo Kam

Master's Theses

A poroelastic finite element model of a heterogeneous articular cartilage disc was

created to examine the tissue response to low amplitude (± 2% strain), low

frequency (0.1 Hz) dynamic unconfined compression (UCC). A strong correlation

has been made between the relative fluid velocity and stimulation of

glycosaminoglycan synthesis. A contour plot of the model shows the relative fluid

velocity during compression exceeds a trigger value of 0.25 μm/s at the radial

periphery. Dynamic UCC biochemical results have also reported a higher

glycosaminoglycan content in this region versus that of day 0 specimens. Fluid

velocity was also found not to be …


Predicting Articular Cartilage Constituent Material Properties Following In Vitro Growth Using A Proteoglycan-Collagen Mixture Model, Michael Stender Mar 2011

Predicting Articular Cartilage Constituent Material Properties Following In Vitro Growth Using A Proteoglycan-Collagen Mixture Model, Michael Stender

Master's Theses

      A polyconvex continuum-level  proteoglycan Cauchy stress function was developed based on the continuum electromechanical Poisson-Boltzmann unit cell model for proteoglycan interactions. The resulting proteoglycan model was combined with a novel collagen fibril model and a ground substance matrix material to create a polyconvex constitutive finite element model of articular cartilage. The true collagen fibril modulus , and the ground substance matrix shear modulus , were varied to obtain the best fit to experimental tension, confined compression, and unconfined compression data for native explants and explants cultured in insulin-like growth factor-1 (IGF-1) and transforming growth factor-β1 (TGF-β1).  Results indicate …


An Investigation Of Humeral Stress Fractures In Racing Thoroughbreds Using A 3d Finite Element Model In Conjunction With A Bone Remodeling Algorithm, Ryan James Moore Feb 2010

An Investigation Of Humeral Stress Fractures In Racing Thoroughbreds Using A 3d Finite Element Model In Conjunction With A Bone Remodeling Algorithm, Ryan James Moore

Master's Theses

The humerus of a racing horse Thoroughbred is highly susceptible to stress fractures at a characteristic location as a result of cyclic loading. The propensity of a Thoroughbred to exhibit humeral fracture has made equines useful models in the epidemiology of stress fractures. In this study, a racing Thoroughbred humerus was simulated during training using a 3D finite element model in conjunction with a bone remodeling algorithm. Nine muscle forces and two contact forces were applied to the 3-dimensional finite element model, which contains four separate load cases representing fore-stance, mid-stance, aft-stance, and standing. Four different training programs were incorporated …


Mechanical Simulation Of Articular Cartilage Based On Experimental Results, Kevin Matthew Stewart Jun 2009

Mechanical Simulation Of Articular Cartilage Based On Experimental Results, Kevin Matthew Stewart

Master's Theses

Recently, a constituent based cartilage growth finite element model (CGFEM) was developed in order to predict articular cartilage (AC) biomechanical properties before and after growth. Previous research has noted limitations in the CGFEM such as model convergence with growth periods greater than 12 days. The main aims of this work were to address these limitations through (1) implementation of an exact material Jacobian matrix definition using the Jaumann-Kirchhoff (J-K) method and (2) quantification of elastic material parameters based upon research findings of the Cal Poly Cartilage Biomechanics Group (CPGBG). The J-K method was successfully implemented into the CGFEM and exceeded …