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Finite element analysis

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Articles 91 - 120 of 134

Full-Text Articles in Mechanical Engineering

Effects Of Local Ph On The Formation And Regulation Of Cristae Morphologies, Dong Hoon Song, Jonghyun Park, Martin A. Philbert, Ann Marie Sastry, Wei Lu Aug 2014

Effects Of Local Ph On The Formation And Regulation Of Cristae Morphologies, Dong Hoon Song, Jonghyun Park, Martin A. Philbert, Ann Marie Sastry, Wei Lu

Mechanical and Aerospace Engineering Faculty Research & Creative Works

Cristae, folded subcompartments of the inner mitochondrial membrane (IMM), have complex and dynamic morphologies. Since cristae are the major site of adenosine triphosphate synthesis, morphological changes of cristae have been studied in relation to functional states of mitochondria. In this sense, investigating the functional and structural significance of cristae may be critical for understanding progressive mitochondrial dysfunction. However, the detailed mechanisms of the formation and regulation of these cristae structures have not been fully elucidated. Among the hypotheses concerning the regulation of cristae morphologies, we exclusively investigate the effects of the local pH gradient on the cristae morphologies by using …


Analytical And Experimental Analysis Of Magnetorheological Elastomers, Sarah Trabia Aug 2014

Analytical And Experimental Analysis Of Magnetorheological Elastomers, Sarah Trabia

UNLV Theses, Dissertations, Professional Papers, and Capstones

Many engineering applications ranging from robotic joints to shock and vibration mitigation can benefit by incorporating components with variable stiffness. In addition, variable stiffness structures can provide haptic feedback (the sense of touch) to the user. In this work, it is proposed to study Magnetorheological Elastomers (MRE), where iron particles within the elastomer compound develop a dipole interaction energy, to be used in a device for haptic feedback. A novel feature of this MRE device is to introduce a field-induced variable shear modulus bias via a permanent magnet and using a current input to the electromagnetic control coil to change …


Finite Element Beam Model For Piezoelectric Energy Harvesting Using Higher Order Shear Deformation Theory, Akhilesh Surabhi Aug 2014

Finite Element Beam Model For Piezoelectric Energy Harvesting Using Higher Order Shear Deformation Theory, Akhilesh Surabhi

All Theses

Piezoelectric energy harvesting devices convert mechanical energy to usable electrical energy, which can be used to power other electronic devices and sensors. Typical piezoelectric harvesters are unimorph cantilever composite beams, which have a single active piezoceramic layer and a passive substrate or a bimorph that has a passive substrate sandwiched between two piezoceramic layers. Power is captured across a coupled load resistor circuit in either a series or parallel connection. The mathematical modeling approaches for piezoelectric beam harvesters present in literature range from analytical distributed parameter modeling, to approximate distributed parameter, Rayleigh- Ritz global discretization or finite element local discretization. …


Computational Optimization Methods For Modeling The Effect Of Muscle Forces On Bone Strength Adaptation, Catherine Siena Florio Jan 2014

Computational Optimization Methods For Modeling The Effect Of Muscle Forces On Bone Strength Adaptation, Catherine Siena Florio

Dissertations

An improved understanding of the mechanical influences that alter the strength of a bone can aid in the refinement of the wide array of currently available techniques to counteract the losses of bone strength that occur due to age or disuse both on Earth and in Space. To address this need, computational modeling methods to quantitatively analyze and compare the effects of mechanical factors on the strength of a targeted bone within a multibone, multimuscle system are developed and implemented in this work. Through a more detailed representation of the system in which the bone acts and the creation of …


Modeling Repair Patches Of Ship Hull And Studying The Effect Of Their Orientation On Stresses, Halima Enwegy Jan 2014

Modeling Repair Patches Of Ship Hull And Studying The Effect Of Their Orientation On Stresses, Halima Enwegy

Electronic Theses and Dissertations

The hull is the most important structural part of any maritime vessel. It must be adequately designed to withstand the harsh sailing environmental conditions and associated forces. In the past, the basic material used to manufacture the ship hull was wood, where the hull was usually shaped as cylindrical wooden shanks. In the present, hull designs have developed to steel columns or stiffened panels that are made of different types of materials. Panels that are stiffened orthogonally in two or more directions and have nine independent material constants are defined as orthotropic panels, and they achieve high specific strength. This …


Effect Of Multi-Tube Injector Geometry On Flame Stability And Nox Emission In A High Pressure Gas Turbine Combustor, Sudipa Sarker Jan 2014

Effect Of Multi-Tube Injector Geometry On Flame Stability And Nox Emission In A High Pressure Gas Turbine Combustor, Sudipa Sarker

Open Access Theses & Dissertations

Future generation gas turbine combustors for power production are expected to have the capability of operating on high hydrogen content fuels. To ensure the implementation of high hydrogen content (HHC) fuel in a power generation unit without negotiating with operational or emission advantages, the study of the flame stability regime and behavior of (HHC) fuel under gas turbine condition leads to the necessity of the development of an optically accessible high-pressure combustor. This Dissertation first presents the design of an optically high-pressure combustor facility based on 500 kW power and 1.5 MPa pressure which is the representative pressure of a …


Developing An Architecture Framework For Cloud-Based, Multi-User, Finite Element Pre-Processing, Jared Calvin Briggs Nov 2013

Developing An Architecture Framework For Cloud-Based, Multi-User, Finite Element Pre-Processing, Jared Calvin Briggs

Theses and Dissertations

This research proposes an architecture for a cloud-based, multi-user FEA pre-processing system, where multiple engineers can access and operate on the same model in a parallel environment. A prototype is discussed and tested, the results of which show that a multi-user preprocessor, where all computing is done on a central server that is hosted on a high performance system, provides significant benefits to the analysis team. These benefits include a shortened preprocessing time, and potentially higher-quality models.


Design Exploration And Analysis Of Carbon-Infiltrated Carbon Nanotube Vascular Stents, Darrell John Skousen Sep 2013

Design Exploration And Analysis Of Carbon-Infiltrated Carbon Nanotube Vascular Stents, Darrell John Skousen

Theses and Dissertations

The purpose of this research was to design, develop, and test coronary stent designs composed of carbon-infiltrated carbon nanotubes (CI-CNTs). Coronary stents currently have two major complications: restenosis and thrombosis. CI-CNT stents have potential to address both of these issues, and therefore may provide improved clinical outcomes. CI-CNT stent geometry is patterned using high-resolution photolithography that provide advantages in design possibilities.To develop a coronary stent, a standard design process was followed including: background, design specifications, concept generation, development, analysis, and testing. Background research was first completed and general design specifications for coronary stent performance were compiled. Multiple design concepts were …


Real-Time Visualization Of Finite Element Models Using Surrogate Modeling Methods, Ryan C. Heap Aug 2013

Real-Time Visualization Of Finite Element Models Using Surrogate Modeling Methods, Ryan C. Heap

Theses and Dissertations

Finite element analysis (FEA) software is used to obtain linear and non-linear solutions to one, two, and three-dimensional (3-D) geometric problems that will see a particular load and constraint case when put into service. Parametric FEA models are commonly used in iterative design processes in order to obtain an optimum model given a set of loads, constraints, objectives, and design parameters to vary. In some instances it is desirable for a designer to obtain some intuition about how changes in design parameters can affect the FEA solution of interest, before simply sending the model through the optimization loop. This could …


Finite Element Analysis Of Effective Mechanical Properties, Vibration And Acoustic Performance Of Auxetic Chiral Core Sandwich Structures, Hrishikesh Joshi Aug 2013

Finite Element Analysis Of Effective Mechanical Properties, Vibration And Acoustic Performance Of Auxetic Chiral Core Sandwich Structures, Hrishikesh Joshi

All Theses

Honeycomb cellular materials are widely used in engineering applications due to their high strength to weight ratio and controllable effective mechanical properties. The effective properties are controlled by varying the geometry of the repetitive unit cells of honeycomb structure. Sandwich panels made of honeycomb cores are beneficial in many applications including vibration isolation and sound transmission reduction. Sandwich panels with standard honeycomb core configurations have previously been studied with regards to sound transmission behavior. It has been established that the auxetic honeycomb cores, having negative in-plane Poisson's ratio, exhibit higher sound transmission loss as compared to regular honeycomb cores. In …


Finite Element Analysis Of Thermomechanical Processes In Disk Clutch Systems, Zhuo Chen Jan 2013

Finite Element Analysis Of Thermomechanical Processes In Disk Clutch Systems, Zhuo Chen

Electronic Theses and Dissertations

The engagement of clutch system is a typical dynamic coupled temperature-displacement process which contains two or more sliding surfaces involved in frictional contact. This process influences evidently the thermal fatigue, noise and vibration of the clutch system. This effect can be more remarkable if the temperature distribution over the clutch disk is not uniform.

This thesis is organized into five chapters:

The first chapter is an introduction which reviews the background and previous work of thermoelastic instability and finite element analysis of clutch system and disk brake.

A parametric analysis of TEI (thermoelastic instability) is elaborated in the second chapter. …


Representing Intersubject Variability With A Statistical Shape And Alignment Model Of The Knee, Chandreshwar Rao Jan 2013

Representing Intersubject Variability With A Statistical Shape And Alignment Model Of The Knee, Chandreshwar Rao

Electronic Theses and Dissertations

Prior statistical shape models have not considered multiple structures in the knee joint to characterize anatomic variation which are required to investigate joint mechanics further for the successful knee replacement. Accordingly, the study's objective was to develop statistical shape and alignment model (SSAM) to capture intersubject variability and demonstrate the ability to generate realistic instances for use in finite element analysis (FEA). SSAM described the variability in the training set of 20 subjects with a series of modes of variation obtained by performing principal component analysis (PCA). PCA produced modes of variation with the first 3 modes representing 70% and …


Improving Student Learning Through Use Of An In-Class Material Processing Design Project, Joseph P. Domblesky, James A. Rice, Jay R. Goldberg, Mark L. Nagurka Jan 2013

Improving Student Learning Through Use Of An In-Class Material Processing Design Project, Joseph P. Domblesky, James A. Rice, Jay R. Goldberg, Mark L. Nagurka

Mechanical Engineering Faculty Research and Publications

At Marquette University, hybrid project-based learning has been implemented in an undergraduate mechanical engineering course on materials processing and forming using a team-based approach. The goals of the project are to 1) introduce more active and student-centered activities to improve student engagement and mastery of core concepts, 2) increase students' confidence in their ability to apply what they learned in the course to solving real-world problems, 3) enable students to gain experience using engineering software as part of the learning process and in applications context. While use of process modeling software in materials processing and manufacturing courses is not entirely …


Stress And Strain Adaptation In Load-Dependent Remodeling Of The Embryonic Left Ventricle, Christine Buffinton Dec 2012

Stress And Strain Adaptation In Load-Dependent Remodeling Of The Embryonic Left Ventricle, Christine Buffinton

Faculty Journal Articles

Altered pressure in the developing left ventricle (LV) results in altered morphology and tissue material properties. Mechanical stress and strain may play a role in the regulating process. This study showed that confocal microscopy, three-dimensional reconstruction, and finite element analysis can provide a detailed model of stress and strain in the trabeculated embryonic heart. The method was used to test the hypothesis that end-diastolic strains are normalized after altered loading of the LV during the stages of trabecular compaction and chamber formation. Stage-29 chick LVs subjected to pressure overload and underload at stage 21 were reconstructed with full trabecular morphology …


The Biomechanical Implications Of An Intrinsic Decompressive Pre-Load On A Posterior Dynamic Stabilization System, Jeffrey Ellis Harris Jul 2012

The Biomechanical Implications Of An Intrinsic Decompressive Pre-Load On A Posterior Dynamic Stabilization System, Jeffrey Ellis Harris

Theses and Dissertations

The purpose of this research was to investigate the influence of applying an intrinsic decompressive pre-load to a particular dynamic stabilization device on the biomechanical response of the lumbar spine. The FlexSPAR, which supports this ability, was used as a test case. A finite element model of a full lumbar spine was developed and validated against experimental data, and tested in the primary modes of spinal motion. The model was used to compare five lumbar spine test cases: healthy, degenerate, implanted with a pre-loaded device, implanted with a device without a pre-load, and implanted with rigid fixators. Results indicated that …


Prediction Of Articular Cartilage Remodeling During Dynamic Compression With A Finite Element Model, Kevin Akira Yamauchi Jun 2012

Prediction Of Articular Cartilage Remodeling During Dynamic Compression With A Finite Element Model, Kevin Akira Yamauchi

Master's Theses

First, an in vitro growth experiment was performed to test the hypothesis that applying dynamic unconfined compression during culture produces het- erogeneous remodeling in newborn bovine articular cartilage explants. Het- erogeneous measures of cartilage microstructure were obtained by biochemical assays and quantified polarized light microscopy. Significant differences were measured between the GAG content in the inner and outer portions of the sam- ples stimulated with dynamic unconfined compression. The COL fiber network was found to be more highly aligned in the inner portion of the sample than in the peripheral region.

Next, a poroelastic finite element model with a remodeling …


Implementation Of Wireless Temperature Sensors For Continuous Condition Monitoring Of Railroad Bearings, Andoni Zagouris Ii May 2012

Implementation Of Wireless Temperature Sensors For Continuous Condition Monitoring Of Railroad Bearings, Andoni Zagouris Ii

Theses and Dissertations - UTB/UTPA

At present there are no existing bearing health monitoring systems capable of continuous monitoring of railroad bearings. Current wayside equipment is used to collect intermittent bearing temperatures, which at times could be every 65 km (~40 mi). To answer this need, IONX, LLC, a subsidiary of Amsted Rail, Inc., has developed low power Wireless Sensor Nodes (WSNs) which can be retrofitted to existing bearing adapters. The WSNs provide continuous monitoring of bearing temperatures as well as the current ambient temperature. Since the nodes are affixed to the bearing adapter surface, a correlation is necessary to estimate the bearing cup temperature …


Compressive Strength Of Continuous Fiber Unidirectional Composites, Ronald Thompson May 2012

Compressive Strength Of Continuous Fiber Unidirectional Composites, Ronald Thompson

All Dissertations

Dow and Rosen's work in 1965 formed an intellectual framework for compressive strength of unidirectional composites. Compressive strength was explained in terms of micro-buckling, in which filaments are beams on an elastic foundation. They made simplifying assumptions, with a two dimensional idealization and linearized material properties. This study builds on their model, recognizing that the shear mode of instability drives unidirectional compressive strength. As a necessary corollary, the predictive methods developed in this study emphasize correct representation of composite shear stiffness. Non-linear effects related to matrix material properties, fiber misalignment, three dimensional representation, and thermal prestrains are taken into account. …


Biomechanical Implications Of Lumbar Spinal Ligament Transectiona Finite Element Study, Gregory Allen Von Forell Jan 2012

Biomechanical Implications Of Lumbar Spinal Ligament Transectiona Finite Element Study, Gregory Allen Von Forell

Theses and Dissertations

The purpose of this work was to determine the possible effects of isolated spinal ligament transection on the biomechanics of the lumbar spine. A finite element model of a lumbar spine was developed and validated against experimental data. The model was tested in the primary modes of spinal motion in the intact condition, followed by comparative analysis of isolated removal of each spinal ligament. Results showed that stress increased in the remaining ligaments once a ligament was removed, potentially leading to ligament damage. Results also showed changes in bone remodeling "stimulus" which could lead to changes in bone density. Isolated …


Arterial Wall Mechanics And Clinical Implications After Coronary Stenting: Comparisons Of Three Stent Designs, Linxia Gu, Shijia Zhao, Stacey R. Froemming Jan 2012

Arterial Wall Mechanics And Clinical Implications After Coronary Stenting: Comparisons Of Three Stent Designs, Linxia Gu, Shijia Zhao, Stacey R. Froemming

Department of Mechanical and Materials Engineering: Faculty Publications

The goal of this work is to quantitatively assess the relationship between the reported restenosis rates and stent induced arterial stress or strain parameters through finite element method. The impact of three stent designs (Palmaz–Schatz stent, Express stent, and Multilink Vision stent) on the arterial stress distributions were characterized. The influences of initial stent deployment location, stent-tissue friction, and plaque properties on the arterial stresses were also investigated. Higher arterial stresses were observed at the proximal end of the plaque. The Multilink–Vision stent induced lesser stress concentrations due to the high stiffness of the Cobalt Chromium material and thinner strut …


Explicit Finite Element Modeling Of The Human Lumbar Spine, Milind Rao Jan 2012

Explicit Finite Element Modeling Of The Human Lumbar Spine, Milind Rao

Electronic Theses and Dissertations

Validated finite element (FE) models of the functional spinal unit (FSU) and lumbar spine are essential in design-phase device development and in assessing the mechanics associated with normal spine function and degenerative disc disease (DDD), as well as the impact of fusion and total disc replacement (TDR). Although experimental data from fully intact specimens can be used for model calibration and validation, the contributions from the individual structures (disc, facets, and ligaments) may be inappropriately distributed. Hence, creation of decompression conditions or device implantations that require structure removal may not have the proper resulting mechanics. An explicit FE formulation may …


Enabling And Understanding Failure Of Engineering Structures Using The Technique Of Cohesive Elements, H. Jiang, Xiaosheng Gao, T. S. Srivatsan Feb 2011

Enabling And Understanding Failure Of Engineering Structures Using The Technique Of Cohesive Elements, H. Jiang, Xiaosheng Gao, T. S. Srivatsan

Mechanical Engineering Faculty Research

In this paper, we describe a cohesive zone model for the prediction of failure of engineering solids and/or structures. A damage evolution law is incorporated into a three-dimensional, exponential cohesive law to account for material degradation under the influence of cyclic loading. This cohesive zone model is implemented in the finite element software ABAQUS through a user defined subroutine. The irreversibility of the cohesive zone model is first verified and subsequently applied for studying cyclic crack growth in specimens experiencing different modes of fracture and/or failure. The crack growth behavior to include both crack initiation and crack propagation becomes a …


Probabilistic Structural And Thermal Analysis Of A Gasketed Flange, Atul G. Tanawade Jan 2011

Probabilistic Structural And Thermal Analysis Of A Gasketed Flange, Atul G. Tanawade

ETD Archive

Performance of a flange joint is characterized mainly by its 'strength' and 'sealing capability'. A number of analytical and experimental studies have been conducted to study these characteristics under internal pressure loading. However, with the advent of new technological trends for high temperature and pressure applications, an increased demand for analysis is recognized. The effect of steady-state thermal loading makes the problem more complex as it leads to combined application of internal pressure and temperature. Structural and thermal analysis of a gasketed flange was computationally simulated by a finite element method and probabilistically evaluated in view of the several uncertainties …


Parallel-Sparse Symmetrical/Unsymmetrical Finite Element Domain Decomposition Solver With Multi-Point Constraints For Structural/Acoustic Analysis, Siroj Tungkahotara, Willie R. Watson, Duc T. Nguyen, Subramaniam D. Rajan Jan 2011

Parallel-Sparse Symmetrical/Unsymmetrical Finite Element Domain Decomposition Solver With Multi-Point Constraints For Structural/Acoustic Analysis, Siroj Tungkahotara, Willie R. Watson, Duc T. Nguyen, Subramaniam D. Rajan

Civil & Environmental Engineering Faculty Publications

Details of parallel-sparse Domain Decomposition (DD) with multi-point constraints (MPC) formulation are explained. Major computational components of the DD formulation are identified. Critical roles of parallel (direct) sparse and iterative solvers with MPC are discussed within the framework of DD formulation. Both symmetrical and unsymmetrical system of simultaneous linear equations (SLE) can be handled by the developed DD formulation. For symmetrical SLE, option for imposing MPC equations is also provided.

Large-scale (up to 25 million unknowns involving complex numbers) structural and acoustic Finite Element (FE) analysis are used to evaluate the parallel computational performance of the proposed DD implementation using …


Experimental And Numerical Analysis Of Structures With Bolted Joints Subjected To Impact Load, Kumarswamy K. Nakalswamy May 2010

Experimental And Numerical Analysis Of Structures With Bolted Joints Subjected To Impact Load, Kumarswamy K. Nakalswamy

UNLV Theses, Dissertations, Professional Papers, and Capstones

The aim of this study is to analyze the transient behavior of structures with bolted joints subjected to impact or shock loads using experimental methods and Finite Element Analysis (FEA). Various factors that affect the response of the bolted joint structures for shock loading were studied, such as damping, preload, intensity of impact load and type of FE modeling. The objective of this work was to develop computational modeling procedures that provide structural analysts an improved physics-based shock model for combat vehicles focusing mainly on shock transmission across bolted joints. There is only a limited amount of published literature describing …


On The Effective Elastic Properties Of Macroscopically Isotropic Media Containing Randomly Dispersed Spherical Particles, D. Cojocaru, Anette M. Karlsson Apr 2010

On The Effective Elastic Properties Of Macroscopically Isotropic Media Containing Randomly Dispersed Spherical Particles, D. Cojocaru, Anette M. Karlsson

Mechanical Engineering Faculty Publications

computational scheme for estimating the effective elastic properties of a particle reinforced matrix is investigated. The randomly distributed same-sized spherical particles are assumed to result in a composite material that is macroscopically isotropic. The scheme results in a computational efficient method to establish the correct bulk and shear moduli by representing the three-dimensional (3D) structure in a two-dimensional configuration. To this end, the statistically equivalent area fraction is defined in this work, which depends on two parameters: the particle volume fraction and the number of particles in the 3D volume element. We suggest that using the statistically equivalent area fraction,introduced …


Flow Induced Vibrations In Pipes: A Finite Element Approach, Ivan Grant Jan 2010

Flow Induced Vibrations In Pipes: A Finite Element Approach, Ivan Grant

ETD Archive

Flow induced vibrations of pipes with internal fluid flow is studied in this work. Finite Element Analysis methodology is used to determine the critical fluid velocity that induces the threshold of pipe instability. The partial differential equation of motion governing the lateral vibrations of the pipe is employed to develop the stiffness and inertia matrices corresponding to two of the terms of the equations of motion. The equation of motion further includes a mixed-derivative term that was treated as a source for a dissipative function. The corresponding matrix with this dissipative function was developed and recognized as the potentially destabilizing …


Finite Element Analysis Of Cracks In Aging Aircraft Structures With Bonded Composite-Patch Repairs, Linxia Gu, Ananth Ram Mahanth Kasavajhala, Shijia Zhao Jan 2010

Finite Element Analysis Of Cracks In Aging Aircraft Structures With Bonded Composite-Patch Repairs, Linxia Gu, Ananth Ram Mahanth Kasavajhala, Shijia Zhao

Department of Mechanical and Materials Engineering: Faculty Publications

Bonded composite-patch repair has been used to transfer load from cracked structures to the reinforcement such that subsequent crack propagation is reduced. In this study,the mechanical behavior of a single edge v-notch A17075-T6 plate repaired with 1-ply and 4-ply composite patches was investigated through the finite element method. Contour integral method was used to define and evaluate the stress intensity factors at the crack tip. The effect of the adhesive epoxy film, patch material, thickness and ply orientations on the evolution of the stress intensity factor (SIF) of the repaired structure was examined. The results indicated that the SIF of …


Simulation Of An Oxidizer-Cooled Hybrid Rocket Throat: Methodology Validation For Design Of A Cooled Aerospike Nozzle, Peter Alexander Brennen Jun 2009

Simulation Of An Oxidizer-Cooled Hybrid Rocket Throat: Methodology Validation For Design Of A Cooled Aerospike Nozzle, Peter Alexander Brennen

Master's Theses

A study was undertaken to create a finite element model of a cooled throat converging/diverging rocket nozzle to be used as a tool in designing a cooled aerospike nozzle. Using ABAQUS, a simplified 2D axisymmetric model was created featuring only the copper throat and stainless steel support ring, which were brazed together for the experimental test firings. This analysis was a sequentially coupled thermal/mechanical model. The steady state thermal data matched closely to experimental data. The subsequent mechanical model predicted a life of over 300 cycles using the Manson-Halford fatigue life criteria. A mesh convergence study was performed to establish …


Simulating The Growth Of Articular Cartilage Explants In A Permeation Bioreactor To Aid In Experimental Protocol Design, Timothy P. Ficklin, Andrew Davol, Stephen M. Klisch Apr 2009

Simulating The Growth Of Articular Cartilage Explants In A Permeation Bioreactor To Aid In Experimental Protocol Design, Timothy P. Ficklin, Andrew Davol, Stephen M. Klisch

Mechanical Engineering

Recently a cartilage growth finite element model (CGFEM) was developed to solve nonhomogeneous and time-dependent growth boundary-value problems (Davol et al., 2008, “A Nonlinear Finite Element Model of Cartilage Growth,” Biomech. Model. Mechanobiol., 7, pp. 295–307). The CGFEM allows distinct stress constitutive equations and growth laws for the major components of the solid matrix, collagens and proteoglycans. The objective of the current work was to simulate in vitro growth of articular cartilage explants in a steady-state permeation bioreactor in order to obtain results that aid experimental design. The steady-state permeation protocol induces different types of mechanical stimuli. When the specimen …