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2020

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Articles 91 - 120 of 1398

Full-Text Articles in Mechanical Engineering

A Distance Based Multisample Test For High-Dimensional Compositional Data With Applications To The Human Microbiome, Qingyang Zhang, Thy Dao Dec 2020

A Distance Based Multisample Test For High-Dimensional Compositional Data With Applications To The Human Microbiome, Qingyang Zhang, Thy Dao

Mathematical Sciences Faculty Publications and Presentations

Background

Compositional data refer to the data that lie on a simplex, which are common in many scientific domains such as genomics, geology and economics. As the components in a composition must sum to one, traditional tests based on unconstrained data become inappropriate, and new statistical methods are needed to analyze this special type of data.

Results

In this paper, we consider a general problem of testing for the compositional difference between K populations. Motivated by microbiome and metagenomics studies, where the data are often over-dispersed and high-dimensional, we formulate a well-posed hypothesis from a Bayesian point of view and …


Nondestructive Evaluation (Nde) Of Additively Manufactured Metal (Amm) Parts Using Ultrasonic Testing (Ut), Austin M. Thomas Dec 2020

Nondestructive Evaluation (Nde) Of Additively Manufactured Metal (Amm) Parts Using Ultrasonic Testing (Ut), Austin M. Thomas

Master's Theses

Additive manufacturing is a category of emerging manufacturing processes that have applications in creating metal components with high value and complexity. The adoption of these parts is limited by the lack of fully developed nondestructive techniques for identifying internal defects. The use of ultrasonic testing for detecting and measuring internal features in additively manufactured metal parts is investigated. A low-cost ultrasonic immersion testing system was designed, constructed, and validated for the inspection of an additively manufactured titanium specimen with artificial defects as well as other metal artifacts. An ultrasound calibration block was additively manufactured from stainless steel type 316L and …


The Varied Thermal Response Of Magnetic Iron-Oxide Nanoparticles During Induction Heating In Liquid And Solid-Liquid Phase Change Mediums, Joshua Tompkins Dec 2020

The Varied Thermal Response Of Magnetic Iron-Oxide Nanoparticles During Induction Heating In Liquid And Solid-Liquid Phase Change Mediums, Joshua Tompkins

Graduate Theses and Dissertations

This study investigates the induction heating response of uncapped iron oxide nanoparticles sonically dispersed as a nanofluid and mechanically distributed in solid phase change materials. The nanoparticles examined have a mean diameter of 14.42 nm and are magnetically heated in an alternating magnetic field at an amplitude of 72.6 kA/m at frequencies of 217, 303, and 397 kHz. Nanoparticle characterization was undertaken through transition electron microscopy, x-ray diffraction, and dynamic light scattering when in suspension. Carrier fluids were characterized through viscosity, heat capacity, and density measurements which were used in the calorimetric calculation of the specific absorption rate (SAR) of …


Adhesion And Deformation Mechanisms Of Polydopamine And Polytetrafluoroethylene: A Multiscale Computational Study, Matthew Brownell Dec 2020

Adhesion And Deformation Mechanisms Of Polydopamine And Polytetrafluoroethylene: A Multiscale Computational Study, Matthew Brownell

Graduate Theses and Dissertations

Polydopamine (PDA) has been shown to bond via covalent bonding, van der Waals forces, and hydrogen bonding and is known to adhere strongly to almost any material. The application of PDA between a substrate and a PTFE surface coating has resulted in low friction and a greatly reduced wear rate. Previous research probing the capabilities and limitations of PDA/PTFE films have studied the wear and mechanical properties of the film, but the overall adhesive and deformation mechanisms remain unclear.

In this research, we investigate the tribological properties of PDA and PTFE molecules and composites from the atomic to the microscale …


Design, Fabrication, And Reliability Effects Of Additively Manufactured First Level Compliant Interconnects For Microelectronics Application, Tumininu David Olatunji Dec 2020

Design, Fabrication, And Reliability Effects Of Additively Manufactured First Level Compliant Interconnects For Microelectronics Application, Tumininu David Olatunji

Graduate Theses and Dissertations

Semiconductor packaging and development is greatly dependent on the magnitude of interconnect and on-chip stress that ultimately limits the reliability of electronic components. Thermomechanical related strains occur because of the coefficient of thermal expansion mismatch from different conjoined materials being assembled to manufacture a device. To curb the effect of thermal expansion mismatch between conjoined parts, studies have been done in integrating compliant structures between dies, solder balls, and substrates. Initial studies have enabled the design and manufacturing of these structures using a photolithography approach which involves a high number of fabrication steps depending on the complexity of the structures …


Mechanical And Frictional Behavior Of Textured And Non-Textured Surfaces, Raghuram R. Santhapuram Dec 2020

Mechanical And Frictional Behavior Of Textured And Non-Textured Surfaces, Raghuram R. Santhapuram

Graduate Theses and Dissertations

Tribology is the study of surfaces where two objects are sliding against another. Significant energy is lost due to friction between the sliding surfaces. Therefore, developing or designing surfaces to minimize friction is critical for the durability and reliability of the mechanical components. Several researchers have identified that surface texturing at the nanoscale (nanotexture) would reduce the friction between the contacting surfaces. The nanotextured surfaces have several applications in microelectromechanical systems and nanoelectromechanical systems. This dissertation employs molecular dynamics simulations to investigate the frictional and mechanical response of nanotextured aluminum (Al) and Al/amorphous silicon (a-Si) composite surfaces.

This study determines …


Numerical Simulations Of Directed Self-Assembly Methods In Di-Block Copolymer Films For Efficient Manufacturing Of Nanoscale Patterns With Long-Range Order, Joseph Hill Dec 2020

Numerical Simulations Of Directed Self-Assembly Methods In Di-Block Copolymer Films For Efficient Manufacturing Of Nanoscale Patterns With Long-Range Order, Joseph Hill

Graduate Theses and Dissertations

Directed self-assembly (DSA) of block copolymers (BCPs) has been shown as a viable method to achieve bulk fabrication of surface patterns with feature sizes smaller than those available through traditional photolithography. Under appropriate thermodynamic conditions, BCPs will self-assemble into ordered micro-domain morphologies, a desirable feature for many applications. One of the primary interests in this field of research is the application of thin-film BCPs to existing photolithography techniques. This “bottom-up” approach utilizes the self-assembled BCP nanostructures as a sacrificial templating layer in the lithographic process.

While self-assembly occurs spontaneously, extending orientational uniformity over centimeter-length scales remains a critical challenge. A …


Nanoscale Mechanics Of Disordered Biomolecules In Brain, Md Ishak Khan Dec 2020

Nanoscale Mechanics Of Disordered Biomolecules In Brain, Md Ishak Khan

Mechanical and Aerospace Engineering Dissertations - Archive

The long-term objective of this dissertation is to link blast-induced traumatic brain injury (TBI) with multiscale, multiphysics damage evolution in the brain using experimentally verifiable computations and simulations. The short-term goal is to conduct modeling and simulation to correlate dynamic mechanical loading to damage in sub-axonal components. It is known that the interior of the brain at the macroscale (10^-1 m) is composed of two distinct components, the grey matter, and the white matter. Within the cortex, the grey matter primarily takes the form of cortical columns (mesoscale: 10^-3 m), which are six layered structures, each composed of 8-10 thousand …


Analytical And Experimental Studies On Mixing In Supersonic Flows, Vijay Gopal Dec 2020

Analytical And Experimental Studies On Mixing In Supersonic Flows, Vijay Gopal

Mechanical and Aerospace Engineering Dissertations - Archive

Mixing enhancement in supersonic flow is an important domain of research for enabling the realization of efficient and scalable high speed air-breathing engines (scramjet). Introducing streamwise vorticies in supersonic flow and tailoring their interactions for mixing enhancement is the primary motivation for the present research study. Leveraging the research performed in the group at the Aerodynamics Research Center (ARC), systematic experimental studies on mixing enhancement is carried out in supersonic flows by tailoring the selected modes of streamwise vortex interactions with the aid of in-house developed reduced order method VorTX. This method utilizes the lifting line-vortex theory in supersonic flow …


Automating Aerospace Synthesis Code Generation A Tool For Generic Vehicle Design And Technology Forecasting, Thomas Peter Mccall Dec 2020

Automating Aerospace Synthesis Code Generation A Tool For Generic Vehicle Design And Technology Forecasting, Thomas Peter Mccall

Mechanical and Aerospace Engineering Dissertations - Archive

The principal development and deliverable of this research is a generic synthesis assembling decision support environment for early conceptual design that automates the assembly of synthesis architectures for enhanced product exploration and technology forecasting. The objective of this research is to develop a baseline environment to assess complex vehicle automated synthesis architecture synthetization procedures for adaptation into a greater cognitive system. This tool has been developed as a precursory and developmental task in an initiative towards an artificial intelligence design and research assistant peer. The artificial intelligence peer is a perceived course for future design system evolution in the continued …


Using Numerical Modeling To Determine Viscous Losses Within Helium Turbomachinery, Benjamin Uhlig Dec 2020

Using Numerical Modeling To Determine Viscous Losses Within Helium Turbomachinery, Benjamin Uhlig

Mechanical and Aerospace Engineering Theses - Archive

As the consumption of energy has increased relentlessly over the last few decades, the need for reliable clean energy generation has increased as well. Currently, nuclear power is the only method capable of providing a stable supply of clean energy, although the nuclear energy generation process still requires improvement. Specifically, there is a need to increase efficiencies while reducing the risks of radioactive contamination. It is possible that both these issues may be mitigated using helium as the working fluid. However, the performance of turbomachinery using helium must be evaluated before its use can be implemented. To do this, Balaji …


Determination Of Landing Zones Of Quadrotors Experiencing In-Flight Failures, Ahmet Tolcu Dec 2020

Determination Of Landing Zones Of Quadrotors Experiencing In-Flight Failures, Ahmet Tolcu

Mechanical and Aerospace Engineering Theses - Archive

In recent years, unmanned aerial vehicles (UAVs), commonly known as drones, have attained considerable prominence in a wide range of areas ranging from military operations, including surveillance, intelligence, and reconnaissance, to nonmilitary sectors such as delivery, entertainment, and agriculture. The low cost, small size, and ease of use of quadrotors provide significant advantages for such missions. At the same time however, the occurrence of physical failures in such vehicles, particularly if these failures occur while flying over highly populated areas, can pose considerable risk to people and premises on the ground. This thesis investigates scenarios of power loss due to …


Experimental Assessment Of Rack-Level Dynamic Direct To Chip Liquid Cooling For Data Center And It Equipment Reliability, Amith Mathew Dec 2020

Experimental Assessment Of Rack-Level Dynamic Direct To Chip Liquid Cooling For Data Center And It Equipment Reliability, Amith Mathew

Mechanical and Aerospace Engineering Theses - Archive

Data centers are used by organizations for storing, processing and distribution of data. These data centers are run through-out the year due to which their thermal management is a growing concern. A popular way of eliminating such thermal cooling issues is Liquid cooling. Conventionally Liquid cooling involves the supply of constant liquid flow (water or refrigerant) through the IT rack irrespective of the IT load, which in a Multi-chip module causes hotspots and temperature gradients across the module due to non-uniform heating. A dynamic cold-plate and a regulatory flow control device (FCD) is incorporated in this experimental set-up to assist …


Field Testing The Effects Of Low Reynolds Number On The Power Performance Of The Cal Poly Wind Power Research Center Small Wind Turbine, John B. Cunningham Dec 2020

Field Testing The Effects Of Low Reynolds Number On The Power Performance Of The Cal Poly Wind Power Research Center Small Wind Turbine, John B. Cunningham

Master's Theses

This thesis report investigates the effects of low Reynolds number on the power performance of a 3.74 m diameter horizontal axis wind turbine. The small wind turbine was field tested at the Cal Poly Wind Power Research Center to acquire its coefficient of performance, p, vs. tip speed ratio, λ, characteristics. A description of both the wind turbine and test setup are provided. Data filtration and processing techniques were developed to ensure a valid method to analyze and characterize wind power measurements taken in a highly variable environment. The test results demonstrated a significant drop in the …


Investigating The Presence Of Culture In Engineering Design: A Case Study On Culture In Design Methods, Perception, And Outcomes, Malena Ataa Durowaah Agyemang Dec 2020

Investigating The Presence Of Culture In Engineering Design: A Case Study On Culture In Design Methods, Perception, And Outcomes, Malena Ataa Durowaah Agyemang

All Dissertations

Overwhelming global statistics on economic, social, and health disparities has driven engineers and designers to develop solutions to minimize these disparities [1,2,11,12,3–10]. For the scope of this study, these efforts are referred to as design for humanitarian engineering and global development (HEGD). HEGD solutions are designed to improve access to medical technologies, energy, clean water, and even spark economic development [1–10]. However, many HEGD solutions go unadopted, halting their intended benefits [9,13,22,23,14–21]. Efforts to improve HEGD adoption have focused on ways to incorporate culture in the design solution’s aesthetics or in approaches post-deployment [24,25,34,35,26–33]. However, a review of failed HEGD …


A Finite State Automata-Based Description Of Device States For Function Modeling Of Multi-State Technical Devices, Ahmed Mohammed Sobhan Chowdhury Dec 2020

A Finite State Automata-Based Description Of Device States For Function Modeling Of Multi-State Technical Devices, Ahmed Mohammed Sobhan Chowdhury

Theses and Dissertations

Many modern and innovative design problems require multi-modal, reconfigurable solutions. Function modeling (FM) is a common tool used to explore solutions in early stages of mechanical engineering design. Currently, function structure representations do not abet the modeling of formally-defined reconfigurable function models as graph-based function models used in early-stage systems design usually represent only one operational mode of the system. Currently there is a need, but no rigorous formalism to model multiple possible modes in the model and logically predict the behavior of the system as it transitions between the modes. Additionally, function modeling representations will benefit from dynamically capturing …


Fluid Modeling And Analysis Of A Mash Tl-6 Vehicle Model, Elisa Vasquez Dec 2020

Fluid Modeling And Analysis Of A Mash Tl-6 Vehicle Model, Elisa Vasquez

Department of Mechanical and Materials Engineering: Dissertations, Theses, and Student Research

The objective of this research project was to replicate the dynamic behavior of a truck-tank trailer combination vehicle using representative dimensions, properties, and inertias of the trailer/fluid ballast combination. A literature review was completed describing techniques for modeling fluids and fluid-container interactions using finite element analysis. Various fluid modeling techniques were identified, and parameters associated with those models were archived. Next, researchers utilized the tank geometry of the elliptical straight-frame 5949 trailer produced by LBT Inc. to generate a finite element mesh using finite element analysis preprocessors HyperMesh and LS PrePost. Material properties were taken from reference guides, research papers, …


Low-Intensity Vibration Restores Nuclear Yap Levels And Acute Yap Nuclear Shuttling In Mesenchymal Stem Cells Subjected To Simulated Microgravity, Matthew Thompson, Kali Woods, Joshua Newberg, Julia Thom Oxford, Gunes Uzer Dec 2020

Low-Intensity Vibration Restores Nuclear Yap Levels And Acute Yap Nuclear Shuttling In Mesenchymal Stem Cells Subjected To Simulated Microgravity, Matthew Thompson, Kali Woods, Joshua Newberg, Julia Thom Oxford, Gunes Uzer

Mechanical and Biomedical Engineering Faculty Publications and Presentations

Reducing the musculoskeletal deterioration that astronauts experience in microgravity requires countermeasures that can improve the effectiveness of otherwise rigorous and time-expensive exercise regimens in space. The ability of low-intensity vibrations (LIV) to activate force-responsive signaling pathways in cells suggests LIV as a potential countermeasure to improve cell responsiveness to subsequent mechanical challenge. Mechanoresponse of mesenchymal stem cells (MSC), which maintain bone-making osteoblasts, is in part controlled by the “mechanotransducer” protein YAP (Yes-associated protein), which is shuttled into the nucleus in response to cyto-mechanical forces. Here, using YAP nuclear shuttling as a measurement outcome, we tested the effect of 72 h …


Additive Manufacturing-Enabled Design, Manufacturing, And Lifecycle Performance, Tao Peng, Yi Zhu, Ming Leu, David Bourell Dec 2020

Additive Manufacturing-Enabled Design, Manufacturing, And Lifecycle Performance, Tao Peng, Yi Zhu, Ming Leu, David Bourell

Mechanical and Aerospace Engineering Faculty Research & Creative Works

No abstract provided.


Analysis Of Glass Transition Temperature Of Pcb & Substrate Using Dynamic Mechanical Analysis & Thermomechanical Analysis, Shristi Yadav Dec 2020

Analysis Of Glass Transition Temperature Of Pcb & Substrate Using Dynamic Mechanical Analysis & Thermomechanical Analysis, Shristi Yadav

Mechanical and Aerospace Engineering Theses - Archive

Electronic Packaging materials and their properties examines the array of packaging architecture, outlining the classification of materials and their use for various tasks requiring performance over time. Glass transition temperature plays a vital role in the field of Electronic Packaging. It is the temperature range where the material changes from a rigid glassy material to a soft (not melted) material and is usually measured in terms of the stiffness or modulus. The commonly used component in today’s electronics world are PCBs and substrate which are an integral part of it. There are few known ways of finding out the Glass …


Minimizing Visual Defects Through Augmentation Of Computer Aided Diamond Rough Planning, Abhijith Prabhu Dec 2020

Minimizing Visual Defects Through Augmentation Of Computer Aided Diamond Rough Planning, Abhijith Prabhu

UNLV Theses, Dissertations, Professional Papers, and Capstones

Many computer aided design systems today utilize a workflow where physically accurate rendering of the product is not a functional component of its design process. This gap in workflow can lead to a sub optimal product or even a longer iterative design process in instances where a product's visual attributes and aesthetics are one their primary functional characteristic.

Diamonds are graded on their carat, color, clarity and cut, referred to as the 4Cs of a diamond; a standard set by G.I.A. and universally agreed upon. The cut of a diamond significantly affects the rest of the characteristics as it modifies …


Synthesis And Characterization Of Non-Pgm Catalysts For Fuel Cell Applications, Sudharsan Sridhar Dec 2020

Synthesis And Characterization Of Non-Pgm Catalysts For Fuel Cell Applications, Sudharsan Sridhar

Masters Theses

Fuel Cells convert the chemical energy of a fuel and an oxidizing agent into electricity through a pair of redox reactions. Proton Exchange Membrane (PEM) fuel cells convert (efficiency-60%) hydrogen and air to power the electric motors with zero emissions, facilitating the development of environmentally friendly and sustainable automobile technologies. One of the major obstacles for larger commercial viability of Fuel Cells for automobile applications is their cost-effectiveness. Currently, fuel cells use platinum as a catalyst material, which is prohibitively expensive for commercial automobile applications. The development of non-Platinum Group Metal (non-PGM) catalyst materials with similar electrochemical performance to that …


Large Displacement J-Integral Double Cantilever Beam (Dcb) Test Method For Mode I Fracture Toughness, Joshua Gunderson Dec 2020

Large Displacement J-Integral Double Cantilever Beam (Dcb) Test Method For Mode I Fracture Toughness, Joshua Gunderson

Boise State University Theses and Dissertations

The J-integral is used to develop an alternative double cantilever beam (DCB) test method for the Mode I fracture toughness suitable for both small and large displacements. The current focus is the experimental determination of the Mode I interlaminar fracture toughness of composite materials, but the method is generally applicable to other similar tests and material systems, such as to the Mode I fracture toughness of adhesives. A series of five identical specimens are tested to compare the linear-elastic fracture mechanics method recommended by ASTM, which makes use of linear beam theory with root rotation, large displacement, and end …


A Comparison Of Pid And Sliding Mode Controllers When Applied To The Orbit Raising Of A Satellite Using Solar Sail Propulsion, Kayla Marie Ormiston Dec 2020

A Comparison Of Pid And Sliding Mode Controllers When Applied To The Orbit Raising Of A Satellite Using Solar Sail Propulsion, Kayla Marie Ormiston

Doctoral Dissertations and Master's Theses

Solar Sail spacecraft have become increasingly popular due to their ability to perform long term missions without the need for propellant. Because solar sail propulsion is so unique, most research has been focused on developing new mechanical control techniques. However, it can be argued that more advanced control algorithms can be used to mitigate the shortcomings of commonly used control actuators, specifically reaction wheels, when applied to solar sails. This thesis will research how a sliding mode controller compares to a PID controller with respect to settling time and state response error over a range of maximum reaction wheel torque …


Extreme Response Analysis Of A Site-Specific Offshore Wind Turbine And Offshore Wind Farm Layout Optimization, Xiaosen Xu Dec 2020

Extreme Response Analysis Of A Site-Specific Offshore Wind Turbine And Offshore Wind Farm Layout Optimization, Xiaosen Xu

Theses and Dissertations

Offshore floating wind turbines have been developed in deep water where bottom-fixed offshore wind turbines are cost-prohibitive. Gulf of Maine has one of the greatest potential wind energy on the east coast. A detailed analysis of metocean data is essential for the dynamic simulation of the floating offshore wind turbine and the offshore wind farm layout optimization. Wave scatter diagram represents the joint probability of significant wave height and peak periods. In the wind energy industry, turbulence intensity is defined as the standard deviation of the horizontal wind speed divided by the average wind speed over certain time period. Uniform …


Deepsea Coral Sample Container, Sara Passantino, Andrew Noble, Casey Smith, Thomas Smith Dec 2020

Deepsea Coral Sample Container, Sara Passantino, Andrew Noble, Casey Smith, Thomas Smith

Mechanical Engineering

In order to better understand the health of our oceans and the species that inhabit them, scientists often collect samples for later analysis onshore. The demanding deep-sea environment makes this collection process a challenging engineering task. Samples must first be located, then removed from the seafloor and stored for transportation to the surface. The performance of the engineered solutions that complete each of these tasks is critical in allowing marine scientists to maximize the insight obtained from their expeditions. Marine Applied Research and Exploration (MARE) is an organization that performs such collection of organisms with the help of remotely operated …


Globally Optimal Passive Compliance Control For Tasks Having Multiple Homotopy Classes, Jacob J. Rice, Joseph M. Schimmels Dec 2020

Globally Optimal Passive Compliance Control For Tasks Having Multiple Homotopy Classes, Jacob J. Rice, Joseph M. Schimmels

Mechanical Engineering Faculty Research and Publications

Redundant serial manipulators with variable stiffness actuators (VSAs) are capable of passive compliance control, in which the elastic behavior of the end-effector is controlled for robust interaction with a stiff environment. This paper addresses the problem of finding the globally optimal joint manipulation path (sequence of joint positions and compliances) that yields a desired task manipulation path (sequence of end-effector positions and compliances) when there is one degree of redundancy. The space of admissible joint paths can be very complex, with multiple bifurcations resulting in multiple homotopy classes of joint paths. Bifurcations due to singularities in the combined kinematic and …


Mono And Multi-Objective Optimization And Modeling Of Machining Performance In Face Milling Of Ti6al4v Alloy, Al Mazedur Rahman Dec 2020

Mono And Multi-Objective Optimization And Modeling Of Machining Performance In Face Milling Of Ti6al4v Alloy, Al Mazedur Rahman

Theses and Dissertations

Titanium alloys are extensively used in numerous industries like aerospace, automotive, military, etc., due to their exclusive characteristics. But machining these alloys has always been challenging for manufacturers. This research investigates the effect of radial depth of cut on cutting forces, tool life, surface roughness (Ra), and material removal rate (MRR) during face milling of Ti6Al4V alloy. It also aims to perform mono and multi-objective optimization of response characteristics to determine the optimal input parameters, namely cutting speed, feed rate, and radial depth of cut. Taguchi method and analysis of variance (ANOVA) have been used for mono-objective optimization, whereas Taguchi-based …


Modeling And Analysis For Unit Cell Size, Material Anisotropy And Material Imperfection Effects Of Cellular Structures Fabricated By Powder Bed Fusion Additive Manufacturing., Yan Wu Dec 2020

Modeling And Analysis For Unit Cell Size, Material Anisotropy And Material Imperfection Effects Of Cellular Structures Fabricated By Powder Bed Fusion Additive Manufacturing., Yan Wu

Electronic Theses and Dissertations

Cellular structures are networks of interconnected struts or walls with porosities and are widely found in many natural load-bearing structures such as plants and bones. Cellular structures offer unique functional characteristics such as high stiffness to weight ratio, tailorable heat transfer coefficient, and enhanced mechanical energy absorption, which makes them highly attractive in various engineering disciplines such as biomedical implants, electrodes, heat exchangers, and lightweight structures. There exists an abundance of literatures that have investigated various mechanical properties of various cellular structures such as Poisson’s ratio, elastic modulus, ultimate strength, yield strength, and failure characteristics. Based on the classic cellular …


Development Of A Pediatric Cardiac Assist Maglev Pump For Use With A Universal Driver System., Landon Heath Tompkins Dec 2020

Development Of A Pediatric Cardiac Assist Maglev Pump For Use With A Universal Driver System., Landon Heath Tompkins

Electronic Theses and Dissertations

Heart failure (HF) remains the leading cause of death, affecting 26 million adults worldwide and 6.5 million adults in the United States. Pediatric HF patients have been a historically underserved population with few options for mechanical circulatory support (MCS) therapy, a leading treatment as an alternative to heart transplantation. To address this clinical need, the Inspired Universal MagLev System is being developed; a low cost, universal magnetically levitated extracorporeal MCS system with interchangeable single-use pumps that will ultimately provide adult and pediatric patients ventricular and respiratory assist therapies. The Inspired Pediatric VAD is the first single-use pump application for this …