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2019

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Articles 301 - 330 of 1647

Full-Text Articles in Mechanical Engineering

Mechanosensitive Epithelial Cell Scattering And Migration On Layered Matrices, Christopher Michael Walter Aug 2019

Mechanosensitive Epithelial Cell Scattering And Migration On Layered Matrices, Christopher Michael Walter

McKelvey School of Engineering Graduate Student Theses & Dissertations

Epithelial cells form multi-layered tissue scaffolding that makes up every organ in the body. Along with epithelial cells, the basement membrane (BM) and connective tissue are composed of various proteins that sculpt the organs and protect them from foreign macromolecules. Epithelial cells respond to various cues, both chemical and mechanical, from their surrounding matrices to aid in maintenance and repair of these layers through degradation and deposition of extracellular matrix (ECM) proteins. In cancer progression, epithelial cells lose their normal function of supporting tissue structure and instead adopt more aggressive behaviors through an epithelial-to-mesenchymal transition (EMT) of their cellular traits. …

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Alternative Approach To Sand Bags For Flood Prevention Through The Use Of 3d Printed Flood Panels, Thomas Beaver, William Mcbryan, Matthew Gilliam Aug 2019

Alternative Approach To Sand Bags For Flood Prevention Through The Use Of 3d Printed Flood Panels, Thomas Beaver, William Mcbryan, Matthew Gilliam

Washington University / UMSL Mechanical Engineering Design Project JME 4110

This is an alternative approach to sand bags which could save time and money when implementing temporary barriers around critical areas during times of flooding in flood plains or areas near rivers.

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Reducing Soil Compaction In Agriculture, Chris Gum, Justin Manzella, Brett Kayman Aug 2019

Reducing Soil Compaction In Agriculture, Chris Gum, Justin Manzella, Brett Kayman

Washington University / UMSL Mechanical Engineering Design Project JME 4110

Our project was to prototype a device to reduce compaction in soil during industrial agricultural processes. We chose to highlight tilling as the process to focus on, but our final design could be adapted to work for many different applications.

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Thermal And Physico-Mechanical Characterizations Of Thromboresistant Polyurethane Films, Aaron C. Wilson, Shih-Feng Chou, Roberto Lozano, Jonathan Y. Chen, Pierre F. Neuenschwander Aug 2019

Thermal And Physico-Mechanical Characterizations Of Thromboresistant Polyurethane Films, Aaron C. Wilson, Shih-Feng Chou, Roberto Lozano, Jonathan Y. Chen, Pierre F. Neuenschwander

Mechanical Engineering Faculty Publications and Presentations

Hemocompatibility remains a challenge for injectable and/or implantable medical devices, and thromboresistant coatings appear to be one of the most attractive methods to down-regulate the unwanted enzymatic reactions that promote the formation of blood clots. Among all polymeric materials, polyurethanes (PUs) are a class of biomaterials with excellent biocompatibility and bioinertness that are suitable for the use of thromboresistant coatings. In this work, we investigated the thermal and physico-mechanical behaviors of ester-based and ether-based PU films for potential uses in thromboresistant coatings. Our results show that poly(ester urethane) and poly(ether urethane) films exhibited characteristic peaks corresponding to their molecular configurations. …

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The Potential Energy States And Mechanical Properties Of Thermally Cycled Binary Glasses, Nikolai V. Priezjev Aug 2019

The Potential Energy States And Mechanical Properties Of Thermally Cycled Binary Glasses, Nikolai V. Priezjev

Mechanical and Materials Engineering Faculty Publications

The influence of repeated thermal cycling on mechanical properties, structural relaxation, and evolution of the potential energy in binary glasses is investigated using molecular dynamics simulations. We consider a binary mixture with strongly non-additive cross interactions, which is annealed across the glass transition with different cooling rates and then exposed to one thousand thermal cycles at constant pressure. We found that during the first few hundred transient cycles, the potential energy minima after each cycle gradually decrease and the structural relaxation proceeds via collective, irreversible displacements of atoms. With increasing cycle number, the amplitudes of the volume and potential energy …

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Elevated Temperature Mechanical And Microstructural Characterization Of Slm Ss304l, G. R. Hecht, Sriram Praneeth Isanaka, Joseph William Newkirk Aug 2019

Elevated Temperature Mechanical And Microstructural Characterization Of Slm Ss304l, G. R. Hecht, Sriram Praneeth Isanaka, Joseph William Newkirk

Materials Science and Engineering Faculty Research & Creative Works

SLM built SS304L was annealed and water quenched to minimize residual stress and avoid carbide precipitation. Mini-tensile characterization of strength and elongation at temperature conditions up to 800°C, along with observations of the associated microstructural transformations were utilized to understand the changes produced in SLM SS304L. As-built and annealed specimens were found to exhibit decreasing strength and elongation with increasing temperature as expected. Carbide precipitates appeared after short times at high temperatures within both as-built and annealed specimens for all cases, but no brittle intermetallic phase development was observed for any of the temperatures investigated. While the lack of Sigma, …

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Frequency Inspection Of Additively Manufactured Parts For Layer Defect Identification, Aimee Allen, Kevin Johnson, Jason R. Blough, Andrew Barnard, Troy Hartwig, Ben Brown, David Soine, Tristan Cullom, Douglas A. Bristow, Robert G. Landers, Edward C. Kinzel Aug 2019

Frequency Inspection Of Additively Manufactured Parts For Layer Defect Identification, Aimee Allen, Kevin Johnson, Jason R. Blough, Andrew Barnard, Troy Hartwig, Ben Brown, David Soine, Tristan Cullom, Douglas A. Bristow, Robert G. Landers, Edward C. Kinzel

Mechanical and Aerospace Engineering Faculty Research & Creative Works

Additive manufactured (AM) parts are produced at low volume or with complex geometries. Identifying internal defects is difficult as current testing techniques are not optimized for AM processes. The goal of this paper is to evaluate defects on multiple parts printed on the same build plate. The technique used was resonant frequency testing with the results verified through Finite Element Analysis. From these tests, it was found that the natural frequencies needed to detect the defects were higher than the excitation provided by a modal hammer. The deficiencies in this range led to the development of other excitation methods. Based …

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Joining Of Copper And Stainless Steel 304l Using Direct Metal Deposition, Xinchang Zhang, Yitao Chen, Tan Pan, Wenyuan Cui, Lan Li, Frank W. Liou Aug 2019

Joining Of Copper And Stainless Steel 304l Using Direct Metal Deposition, Xinchang Zhang, Yitao Chen, Tan Pan, Wenyuan Cui, Lan Li, Frank W. Liou

Mechanical and Aerospace Engineering Faculty Research & Creative Works

In the current study, the feasibility of joining pure copper (Cu) and stainless steel 304L (SS304L) through direct metal deposition process was investigated by material characterization. Samples were analyzed in terms of microstructure, elemental distribution, and tensile testing. Direct depositing pure copper on SS304L shows copper was mechanically rather than metallurgical bonded with SS304L due to the poor dissolubility of iron in copper. Iron was diffused into copper with a diluted distance of 1.5 mm and above that, pure copper deposits were obtained. Columnar structure was observed at the copper region near the interface while the columnar grains became finer …

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Simulated Effect Of Laser Beam Quality On The Robustness Of Laser-Based Am System, Aaron Flood, Frank W. Liou Aug 2019

Simulated Effect Of Laser Beam Quality On The Robustness Of Laser-Based Am System, Aaron Flood, Frank W. Liou

Mechanical and Aerospace Engineering Faculty Research & Creative Works

In many metal AM techniques, a laser is used as the heat source and in some applications, it can be advantageous to work off of the focal plane. When operating outside of focus, the beam quality of the laser can have drastic impacts on the ability to manufacture quality parts. This study investigates the effect of the beam quality and distance from the focal plan on the ability to deposit Ti-64, aluminum, and steel through the simulation of the blown powder process.

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In-Situ Local Part Qualification Of Slm 304l Stainless Steel Through Voxel Based Processing Of Swir Imaging Data, Cody S. Lough, Xin Wang, Robert G. Landers, Douglas A. Bristow, James A. Drallmeier, Edward C. Kinzel Aug 2019

In-Situ Local Part Qualification Of Slm 304l Stainless Steel Through Voxel Based Processing Of Swir Imaging Data, Cody S. Lough, Xin Wang, Robert G. Landers, Douglas A. Bristow, James A. Drallmeier, Edward C. Kinzel

Mechanical and Aerospace Engineering Faculty Research & Creative Works

This paper demonstrates the potential for qualification through local part property prediction of 304L stainless steel parts manufactured by Selective Laser Melting (SLM). This is accomplished through voxel based processing of SWIR imaging data measured in-situ. Thermal features are extracted from time-series SWIR imaging data recorded from layer-to-layer to generate 3D point cloud reconstructions of parts. The voxel based data is indexed with localized measurements of SLM part properties (light-to-dark microstructural feature ratio, microhardness, μCT data) to demonstrate the correlations. Various features are extracted from the thermal history for comparison of their respective abilities to predict the resulting local part …

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Compressive And Bending Performance Of Selectively Laser Melted Alsi10mg Structures, D. Murphy, O. Fashanu, Myranda Spratt, Joseph William Newkirk, K. Chandrashekhara, H. Misak, D. Klenosky Aug 2019

Compressive And Bending Performance Of Selectively Laser Melted Alsi10mg Structures, D. Murphy, O. Fashanu, Myranda Spratt, Joseph William Newkirk, K. Chandrashekhara, H. Misak, D. Klenosky

Materials Science and Engineering Faculty Research & Creative Works

Selective laser melting (SLM) is a widely used additive manufacturing technique that effectively manufactures complex geometries such as cellular structures. However, challenges such as anisotropy and mechanical property variation are commonly found due to process parameters. In a bid to utilize this method for the commercial production of cellular structures, it is important to understand the behavior of a material under different loading conditions. In this work, the behavior of additively manufactured AlSi10Mg under compression, bending, and tension loads was investigated. Vertical and horizontal build directions are compared for each type of loading. Specimens were manufactured using the reduced build …

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Comparison Of Fatigue Performance Between Additively Manufactured And Wrought 304l Stainless Steel Using A Novel Fatigue Test Setup, M. M. Parvez, Y. Chen, Joseph William Newkirk, Frank W. Liou Aug 2019

Comparison Of Fatigue Performance Between Additively Manufactured And Wrought 304l Stainless Steel Using A Novel Fatigue Test Setup, M. M. Parvez, Y. Chen, Joseph William Newkirk, Frank W. Liou

Materials Science and Engineering Faculty Research & Creative Works

In this research, a novel adaptive controlled fatigue testing machine was designed for bending type high cycle fatigue test. A unique dual gauge section Krouse type mini specimen was designed for simply supported transverse bending. Displacement controlled fatigue tests were implemented using an electromechanical actuator. The variation in the control signal and load observed during the test provides unique insights into realizing the deterioration of the specimen due to fatigue. These analyses were utilized to compare the fatigue performance of wrought and additively manufactured 304L stainless steel. The influence of the build direction on fatigue performance was also investigated by …

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Effective Elastic Properties Of Additively Manufactured Metallic Lattice Structures: Unit-Cell Modeling, Okanmisope Fashanu, David Murphy, Myranda Spratt, Joseph William Newkirk, K. Chandrashekhara, Ben Brown, John Porter Aug 2019

Effective Elastic Properties Of Additively Manufactured Metallic Lattice Structures: Unit-Cell Modeling, Okanmisope Fashanu, David Murphy, Myranda Spratt, Joseph William Newkirk, K. Chandrashekhara, Ben Brown, John Porter

Materials Science and Engineering Faculty Research & Creative Works

Lattice structures are lightweight materials, which exhibit a unique combination of properties such as air and water permeability, energy and acoustic absorption, low thermal conductivity, and electrical insulation. In this work, unit-cell homogenization was used to predict the effective elastic moduli of octet-truss (OT) lattice structures manufactured using selective laser melting (SLM). OT structures were manufactured using a Renishaw AM 250 SLM machine with various relative densities. Compression test was carried out at strain rate 5 x 10-3 m-1 using an MTS frame. Finite element analysis was used in the determination of the OT’s effective elastic properties. Results …

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Dynamic Defect Detection In Additively Manufactured Parts Using Fea Simulation, Kevin Johnson, Aimee Allen, Jason R. Blough, Andrew Barnard, David Labyak, Troy Hartwig, Ben Brown, David Soine, Tristan Cullom, Edward C. Kinzel, Douglas A. Bristow, Robert G. Landers Aug 2019

Dynamic Defect Detection In Additively Manufactured Parts Using Fea Simulation, Kevin Johnson, Aimee Allen, Jason R. Blough, Andrew Barnard, David Labyak, Troy Hartwig, Ben Brown, David Soine, Tristan Cullom, Edward C. Kinzel, Douglas A. Bristow, Robert G. Landers

Mechanical and Aerospace Engineering Faculty Research & Creative Works

The goal of this paper is to evaluate internal defects in additively manufactured (AM) parts using FEA simulation. The resonant frequencies of parts are determined by the stiffness and mass involved in the mode shape at each resonant frequency. Voids in AM parts will change the stiffness and mass therefore shift the resonant frequencies from nominal. This paper will investigate the use of FEA to determine how much a void size, shape, and location will change the resonant frequencies. Along with where the optimal input and response locations are in order to find these frequency changes. The AM part evaluated …

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Frequency Domain Measurements Of Melt Pool Recoil Pressure Using Modal Analysis And Prospects For In-Situ Non-Destructive Testing, Tristan Cullom, Nicholas Altese, Douglas A. Bristow, Robert G. Landers, Ben Brown, Troy Hartwig, David Soine, Aimee Allen, Andrew Barnard, Jason Blough, Kevin Johnson, Edward C. Kinzel Aug 2019

Frequency Domain Measurements Of Melt Pool Recoil Pressure Using Modal Analysis And Prospects For In-Situ Non-Destructive Testing, Tristan Cullom, Nicholas Altese, Douglas A. Bristow, Robert G. Landers, Ben Brown, Troy Hartwig, David Soine, Aimee Allen, Andrew Barnard, Jason Blough, Kevin Johnson, Edward C. Kinzel

Mechanical and Aerospace Engineering Faculty Research & Creative Works

Fielding Additively Manufactured (AM) parts requires evaluating both the part’s geometry and material state. This includes geometry that may be optically hidden. Both the geometry and material state affect the vibration response of the parts and modal analysis (identifying natural frequencies) has been shown to be effective for at least simple geometries using ex-situ methods (shaker table and impact hammer excitations). This paper investigates evaluation of the frequency response of metal parts inside the build chamber using the process laser to excite the parts during printing (Renishaw AM250). Vibrations in the part are measured with accelerometers connected to the build …

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The Effect Of Cell Size And Surface Roughness On The Compressive Properties Of Abs Lattice Structures Fabricated By Fused Deposition Modeling, Leah Mason, Ming-Chuan Leu Aug 2019

The Effect Of Cell Size And Surface Roughness On The Compressive Properties Of Abs Lattice Structures Fabricated By Fused Deposition Modeling, Leah Mason, Ming-Chuan Leu

Mechanical and Aerospace Engineering Faculty Research & Creative Works

Researchers looking to improve the surface roughness of acrylonitrile butadiene styrene (ABS) parts fabricated by fused deposition modeling (FDM) have determined that acetone smoothing not only achieves improved surface roughness but increases compressive strength as well. However, the sensitivity of ABS parts to acetone smoothing has not been explored. In this study we investigated FDM-fabricated ABS lattice structures of various cell sizes subjected to cold acetone vapor smoothing to determine the combined effect of cell size and acetone smoothing on the compressive properties of the lattice structures. The acetone-smoothed specimens performed better than the as-built specimens in both compression modulus …

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Application Of Schlieren Technique In Additive Manufacturing: A Review, R. Bharadwaja, Aravind Murugan, Yitao Chen, Frank W. Liou Aug 2019

Application Of Schlieren Technique In Additive Manufacturing: A Review, R. Bharadwaja, Aravind Murugan, Yitao Chen, Frank W. Liou

Mechanical and Aerospace Engineering Faculty Research & Creative Works

Additive manufacturing has gained a lot of attention in the past few decades due to its significant advantages in terms of design freedom, lower lead time, and ability to produce complex shapes. One of the pivotal factors affecting the process stability and hence the part quality is the shielding gas flow in additive manufacturing. As extremely beneficial for the process, the shielding gas flow is often set at maximum supply to achieve enough gas cover over the substrate. This causes excessive quantity of shielding gas to be unutilized. Realizing the importance of shielding gas, various studies have been carried out …

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Applications Of Supervised Machine Learning Algorithms In Additive Manufacturing: A Review, M. S. Joshi, Aaron Flood, Todd E. Sparks, Frank W. Liou Aug 2019

Applications Of Supervised Machine Learning Algorithms In Additive Manufacturing: A Review, M. S. Joshi, Aaron Flood, Todd E. Sparks, Frank W. Liou

Mechanical and Aerospace Engineering Faculty Research & Creative Works

Additive Manufacturing (AM) simplifies the fabrication of complex geometries. Its scope has rapidly expanded from the fabrication of pre-production visualization models to the manufacturing of end use parts driving the need for better part quality assurance in the additively manufactured parts. Machine learning (ML) is one of the promising techniques that can be used to achieve this goal. Current research in this field includes the use of supervised and unsupervised ML algorithms for quality control and prediction of mechanical properties of AM parts. This paper explores the applications of supervised learning algorithms - Support Vector Machines and Random Forests. Support …

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Part Remanufacturing Using Hybrid Manufacturing Processes, Xinchang Zhang, Frank W. Liou Aug 2019

Part Remanufacturing Using Hybrid Manufacturing Processes, Xinchang Zhang, Frank W. Liou

Mechanical and Aerospace Engineering Faculty Research & Creative Works

Many users of high-performance metal parts, such as the aerospace industry, the mold/die casting industry, and heavy machinery consumers, extend the service of these damaged parts by employing remanufacturing technology. Additive manufacturing has unique capabilities, such as low heat input, a small heat-affected zone, free-form fabrication, and a near-net-shape. This paper summarizes the effort and the tested results to achieve an automated remanufacturing process using hybrid additive manufacturing and CNC machining processes. It will enable the robust remanufacturing-on-demand to significantly increase operational availability to reduce sustainment costs, thus will lead to robust and quality remanufacturing that is critical for remanufacturing …

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Design And Validation Of A Modular Instrument To Measure Torque And Energy Consumption In Industrial Operations, Mary De La Cruz, Ramiro Gonzalez, Jesus A. Gomez, Atilano Mendoza, Javier A. Ortega Aug 2019

Design And Validation Of A Modular Instrument To Measure Torque And Energy Consumption In Industrial Operations, Mary De La Cruz, Ramiro Gonzalez, Jesus A. Gomez, Atilano Mendoza, Javier A. Ortega

Mechanical Engineering Faculty Publications

A modular torque measuring instrument capable of performing tapping torque tests (TTT) according to the ASTM D-5619 standard was designed, developed, and validated. With this new instrument, the performance of different lubricants can be evaluated in terms of frictional torque and energy consumption during tapping processes. This instrument can adapt onto any conventional milling machine or CNC machine and operate under various machining operations such as tapping, drilling, and other processes. To validate the design and performance of this new device, three commercially available lubricants were evaluated. From the three tested conditions, the results showed good repeatability, with consistent results …

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Acute Angle Repositioning In Mobile C-Arm Using Image Processing And Deep Learning, Armin Yazdanshenas Aug 2019

Acute Angle Repositioning In Mobile C-Arm Using Image Processing And Deep Learning, Armin Yazdanshenas

Mechanical Engineering Theses

During surgery, medical practitioners rely on the mobile C-Arm medical x-ray system (C-Arm) and its fluoroscopic functions to not only perform the surgery but also validate the outcome. Currently, technicians reposition the C-Arm arbitrarily through estimation and guesswork. In cases when the positioning and repositioning of the C-Arm are critical for surgical assessment, uncertainties in the angular position of the C-Arm components hinder surgical performance. This thesis proposes an integrated approach to automatically reposition C-Arms during critically acute movements in orthopedic surgery. Robot vision and control with deep learning are used to determine the necessary angles of rotation for desired …

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One Knee Stair Negotiator, Naomi Marciante, Seth Trevino Aug 2019

One Knee Stair Negotiator, Naomi Marciante, Seth Trevino

Washington University / UMSL Mechanical Engineering Design Project JME 4110

The design-to-prototype process for a One Knee Stair Negotiator, designed to reduce or eliminate the weight on one leg while climbing stairs. The decision-making processes, fabrication plan, engineering analysis, safety concerns, and risk assessments are documented. Pertinent photographs, drawings, and video links are included for clarification.

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Jme 4110 Mechanical Engineering Design Project:Stir It Up, Josephn Biermann, Brittany Gray, Nathan Hopper Aug 2019

Jme 4110 Mechanical Engineering Design Project:Stir It Up, Josephn Biermann, Brittany Gray, Nathan Hopper

Washington University / UMSL Mechanical Engineering Design Project JME 4110

We are designing and building a working prototype that will be able to mix a separated beverage back to a fully integrated state. This will allow for mixing in a beverage that was separated and would possibly just be thrown away because it doesn’t taste right anymore. This will save food waste from separated beverages being thrown away as well as be environmentally friendly since it would reduce the use of single use cups and straws.

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Automated Single Stream Recycling Sorting Bin (Assrsb), Daniel Pogue, Robert O'Neill, Javi Perez Aug 2019

Automated Single Stream Recycling Sorting Bin (Assrsb), Daniel Pogue, Robert O'Neill, Javi Perez

Washington University / UMSL Mechanical Engineering Design Project JME 4110

As you probably know, there are many different sorting systems used by various manufacturers. It would be desirable to have a similar sorting system that uses multiple technologies to sort items, but that could easily be interchangeable with various items. Currently, recycling efforts are often costly, as humans need to sort single-stream recycling. It would be beneficial to have a system that sorts various plastic, paper, cardboard, glass, etc.

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Portable Car Lift, Ramiz Ahmed, Emel Saeidghafelpoor, Nick Pusateri Aug 2019

Portable Car Lift, Ramiz Ahmed, Emel Saeidghafelpoor, Nick Pusateri

Washington University / UMSL Mechanical Engineering Design Project JME 4110

No abstract provided.

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Optimus Pipefitter, Jeffrey Strecker, Vito Fiordimondo, Ben Prinster Aug 2019

Optimus Pipefitter, Jeffrey Strecker, Vito Fiordimondo, Ben Prinster

Washington University / UMSL Mechanical Engineering Design Project JME 4110

As climate change becomes a larger threat, the idea of space travel becomes a less abstract idea. If we, as a species, get to a point where settling on a new planet becomes a necessity it would be worthwhile for as much infrastructure to be built before our arrival as possible. The problem this project solves is the ability to autonomously assemble piping for plumbing and drainage. To most people, piping is not what comes to mind when thinking about modern living. Although it is certainly essential.

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The Body Dryer Project, Laura Bailey, Luke Maichel, Nick Zuelke Aug 2019

The Body Dryer Project, Laura Bailey, Luke Maichel, Nick Zuelke

Washington University / UMSL Mechanical Engineering Design Project JME 4110

The information contained in this report pertains to the engineering practices to develop a working prototype of a body dryer. A body dryer that is described in the context of this report, is defined as a static structure with two air streams. The main function of the body dryer project is to investigate a replacement for a towel when one is finished showering or after swimming. This report will contain future improvements that were investigated but were not able to implement in the working prototype due to the boundaries of the system. A special shout out to Indoor Comfort Team, …

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Surface Kinetic Energy Distributions In The Global Oceans From A High-Resolution Numerical Model And Surface Drifter Observations, Xiaolong Yu, Aurelien Ponte, Shane Elipot, Dimitris Menemenlis, Edward Zaron, Ryan Abernathey Aug 2019

Surface Kinetic Energy Distributions In The Global Oceans From A High-Resolution Numerical Model And Surface Drifter Observations, Xiaolong Yu, Aurelien Ponte, Shane Elipot, Dimitris Menemenlis, Edward Zaron, Ryan Abernathey

Civil and Environmental Engineering Faculty Publications and Presentations

The surface kinetic energy of a 1/48◦ global ocean simulation and its distribution as a function of frequency and location are compared with the one estimated from 15,329 globally distributed surface drifter observations at hourly resolution. These distributions follow similar patterns with a dominant low-frequency component and well-defined tidal and near-inertial peaks globally. Quantitative differences are identified with deficits of low-frequency energy near the equator (factor 2) and at near-inertial frequencies (factor 3) and an excess of energy at semidiurnal frequencies (factor 4) for the model. Owing to its hourly resolution and its near-global spatial coverage, the array of surface …

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Communication: First-Principles Evaluation Of Alkali Ion Adsorption And Ion Exchange In Pure Silica Lta Zeolite (Vol 149, 131102, 2018), Vancho Kocevski, Benjamin D. Zeidman, Charles H. Henager Jr., Theodore M. Besmann Aug 2019

Communication: First-Principles Evaluation Of Alkali Ion Adsorption And Ion Exchange In Pure Silica Lta Zeolite (Vol 149, 131102, 2018), Vancho Kocevski, Benjamin D. Zeidman, Charles H. Henager Jr., Theodore M. Besmann

Faculty Publications

Using first-principles calculations, we studied the adsorption of alkali ions in pure silica Linde Type A (LTA) zeolite. The probability of adsorbing alkali ions from solution and the driving force for ion exchange between Na+ and other alkali ions at the different adsorption sites were analyzed. From the calculated ion exchange isotherms, we show that it is possible to exchange Na+ with K+ and Rb+ in water, but that is not the case for systems in a vacuum. We also demonstrate that a solvation model should be used for the accurate representation of ion exchange in an LTA and that …

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The Linc Complex, Mechanotransduction, And Mesenchymal Stem Cell Function And Fate, Tasneem Bouzid, Eunju Kim, Brandon D. Riehl, Amir Monemian Esfahani, Jordan Rosebohm, Ruiguo Yang, Bin Duan, Jung Yul Lim Aug 2019

The Linc Complex, Mechanotransduction, And Mesenchymal Stem Cell Function And Fate, Tasneem Bouzid, Eunju Kim, Brandon D. Riehl, Amir Monemian Esfahani, Jordan Rosebohm, Ruiguo Yang, Bin Duan, Jung Yul Lim

Department of Mechanical and Materials Engineering: Faculty Publications

Mesenchymal stem cells (MSCs) show tremendous promise as a cell source for tissue engineering and regenerative medicine, and are understood to be mechanosensitive to external mechanical environments. In recent years, increasing evidence points to nuclear envelope proteins as a key player in sensing and relaying mechanical signals in MSCs to modulate cellular form, function, and differentiation. Of particular interest is the Linker of Nucleoskeleton and Cytoskeleton (LINC) complex that includes nesprin and SUN. In this review, the way in which cells can sense external mechanical environments through an intact nuclear envelope and LINC complex proteins will be briefly described. Then, …

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