Mechanical Engineering Commons^™

Scalability Of Incompressible Flow Computations On Multi-Gpu Clusters Using Dual-Level And Tri-Level Parallelism, Dana A. Jacobsen, Inanc Senocak

Mechanical and Biomedical Engineering Faculty Publications and Presentations

High performance computing using graphics processing units (GPUs) is gaining popularity in the scientific computing field, with many large compute clusters being augmented with multiple GPUs in each node. We investigate hybrid tri-level (MPI-OpenMP-CUDA) parallel implementations to explore the efficiency and scalability of incompressible flow computations on GPU clusters up to 128 GPUS. This work details some of the unique issues faced when merging fine-grain parallelism on the GPU using CUDA with coarse-grain parallelism using OpenMP for intra-node and MPI for inter-node communication. Comparisons between the tri-level MPI-OpenMP-CUDA and dual-level MPI-CUDA implementations are shown using computationally large computational fluid dynamics …

The Hemocompatibility Of A Nitric Oxide Generating Polymer That Catalyzes S-Nitrosothiol Decomposition In An Extracorporeal Circulation Model, Terry C. Major, David O. Brant, Charles P. Burney, Kagya Amoako, Gail M. Annich, Mark E. Meyerhoff, Hitesh Handa, Robert E. Bartlett

Mechanical and Industrial Engineering Faculty Publications

Nitric oxide (NO) generating (NOGen) materials have been shown previously to create localized increases in NO concentration by the catalytic decomposition of blood S-nitrosothiols (RSNO) via copper (Cu)-containing polymer coatings and may improve extracorporeal circulation (ECC) hemocompatibility. In this work, a NOGen polymeric coating composed of a Cuo-nanoparticle (80 nm)-containing hydrophilic polyurethane (SP-60D-60) combined with the intravenous infusion of an RSNO, S- nitroso-N-acetylpenicillamine (SNAP), is evaluated in a 4 h rabbit thrombogenicity model and the anti-thrombotic mechanism is investigated. Polymer films containing 10 wt.% Cuo-nanoparticles coated on the inner walls of ECC circuits are employed concomitantly with systemic SNAP administration …

Nitric Oxide-Generating Silicone As A Blood-Contacting Biomaterial, Kagya Amoako

Mechanical and Industrial Engineering Faculty Publications

Coagulation upon blood-contacting biomaterials remains a problem for short and long-term clinical applications. This study examined the ability of copper(II)-doped silicone surfaces to generate nitric oxide (NO) and locally inhibit coagulation. Silicone was doped with 3-micron copper (Cu(0)) particles yielding 3 to 10 weight percent (wt%) Cu in 70-μm thick Cu/Silicone polymeric matrix composites (Cu/Si PMCs). At 3, 5, 8 and 10 wt% Cu doping, the surface expression of Cu was 12.1 ± 2.8%, 19.7 ± 5.4%, 29.0 ± 3.8%, and 33.8 ± 6.5% respectively. After oxidizing Cu(0) to Cu(II) by spontaneous corrosion, NO flux, JNO (mol*cm−2*min−1), as measured by …

Finite Element Reconstruction Of Real World Aortic Injury In Near-Side Lateral Automotive Crashes With Conceptual Countermeasures, Aditya Neelakanta Belwadi

Wayne State University Dissertations

Traumatic rupture of the aorta (TRA) remains the second most common cause of death associated with motor vehicle crashes after brain injury. On an average, nearly 8,000 people die annually in the United States due to blunt injury to the aorta. It is observed that more than 80% of occupants who suffer an aortic injury die at the scene due to exsanguination into the chest. With the advent of more accurate and established human body finite element (FE) models, FE crash reconstruction methods may become a valuable tool when assessing crash scenarios and occupant injury mechanisms.

The current study is …

Locating And Extracting Acoustic And Neural Signals, Na Zhu

Wayne State University Dissertations

This dissertation presents innovate methodologies for locating, extracting, and separating multiple incoherent sound sources in three-dimensional (3D) space; and applications of the time reversal (TR) algorithm to pinpoint the hyper active neural activities inside the brain auditory structure that are correlated to the tinnitus pathology. Specifically, an acoustic modeling based method is developed for locating arbitrary and incoherent sound sources in 3D space in real time by using a minimal number of microphones, and the Point Source Separation (PSS) method is developed for extracting target signals from directly measured mixed signals. Combining these two approaches leads to a novel technology …

Creep Behaviour Of Hand Laminated Glass Reinforced Polymer Composites., Brian Quinn

Theses

The creep behaviour of hand laminated, glass fiber reinforced polyester composites were studied at coupon level, due to the use of similar materials in long term load bearing civil and structural engineering applications. Creep predictions were made by fitting the parameters of several viscoelastic models to experimental creep data as well as two accelerated test methods, time temperature superposition (TTS) and frequency time transformations (FTT). TTS experiments were carried out in a dynamic mechanical analyzer (DMA) in three point bending mode for three types of material systems. Creep compliance master curves representing the linear viscoelastic creep response at reference temperatures …

Estimation Of The Centre Of Mass From Motion Capture And Force Plate Recordings: A Study On The Elderly, Sebastien Cotton, Michele Vanoncini, Philippe Fraisse, Nacim Ramdani, Emel Demircan, Andrew P. Murray, Thierry Keller

Mechanical and Aerospace Engineering Faculty Publications

The estimation of the centre of mass position in humans is usually based on biomechanical models developed from anthropometric tables. This method can potentially introduce errors in studies involving elderly people, since the ageing process is typically associated with a modification of the distribution of the body mass. In this paper, an alternative technique is proposed, and evaluated with an experimental study on 9 elderly volunteers. The technique is based on a virtual chain, identified from experimental data and locating the subject's centre of mass. Its configuration defines the location of the centre of mass, and is a function of …

Using Thermally Coupled Reactive Distillation Columns In Biodiesel Production, Nghi Nguyen, Yaşar Demirel

Yaşar Demirel Publications

Production of ethyl dodecanoate (biodiesel) using lauric acid and methanol with a solid acid catalyst of sulfated zirconia is studied by using two distillation sequences. In the first sequence, the methanol recovery column follows the reactive distillation column. In the second sequence, the reactive distillation and methanol recovery columns are thermally coupled. Thermally coupled distillation sequences may consume less energy by allowing interconnecting vapor and liquid streams between the two columns to elminate reboiler or condenser or both. Here we study the thermally coupled side-stripper reactive distillation and eliminate the condenser of the reactive distillation column. Both the sequences are …

Role Of Hydrodynamic Behavior Of Dna Molecules In Dielectrophoretic Polarization Under The Action Of An Electric Field, Hui Zhao

Mechanical Engineering Faculty Research

A continuum model is developed to predict the dielectrophoretic polarizability of coiled DNA molecules under the action of an alternating current electric field. The model approximates the coiled DNA molecule as a charged porous spherical particle. The model explains the discrepancies among scaling laws of polarizability of different-sized DNA molecules with contour length and such discrepancies are attributed to different hydrodynamic behavior. With zero or one fitting parameter, theoretical predictions are in good agreement with various experimental data, even though in experiments there are some uncertainties in regard to certain parameters.

A Microfluidic Device For Impedance Spectroscopy, Ahmet Can Sabuncu

Mechanical & Aerospace Engineering Theses & Dissertations

Recently, microfluidics has become a versatile tool to investigate cellular biology and to build novel biomedical devices. Dielectric spectroscopy, on the other hand, allows non-invasive probing of biological cells. Information on the cell membrane, cytoplasm, and nucleus can be obtained by dielectric spectroscopy provided that appropriate tools are used in specific frequency ranges. This dissertation includes fabrication, characterization, and testing of a simple microfluidic device to measure cell dielectric properties. The dielectric measurements are performed on human T-cell leukemia (Jurkat), mouse melanoma (B16), mouse hepatoma (Hepa), and human costal chondrocyte cells. Dielectric measurements consist of measuring the complex impedance of …

Experimental And Computational Analysis Of An Energy Storage Composite Ankle Foot Orthosis, Michelle C. Hawkins

UNLV Theses, Dissertations, Professional Papers, and Capstones

Ankle Foot Orthotics (AFOs) are used by individuals presenting with Charcot-Marie-Tooth (CMT) to assist with improving gait. Mitch Warner, CPO, has developed a composite AFO made from woven carbon-Kevlar and carbon fiber lamina. The overall goals of the research are to characterize the HELIOS brace and to determine its effect on the gait of CMT subjects. Human motion analysis, experimental mechanical testing, and Finite Element Analysis (FEA) are used to gain a better understanding of how the materials and geometric design of the HELIOS AFO contribute to gait.

Human motion experiments are performed to determine the relationship between ground reaction …

Personal Navigation Via High-Resolution Gait-Corrected Inertial Measurement Units, Özkan Bebek, Michael A. Suster, Srihari Rajgopal, Michael J. Fu, Xuemei Huang, M. Cenk Çavu¸So˘Glu,, Darrin J. Young, Mehran Mehregany, Antonie J. Van Den Bogert, Carlos H. Mastrangelo

Mechanical Engineering Faculty Publications

In this paper, a personal micronavigation system that uses high-resolution gait-corrected inertial measurement units is presented. The goal of this paper is to develop a navigation system that uses secondary inertial variables, such as velocity, to enable long-term precise navigation in the absence of Global Positioning System (GPS) and beacon signals. In this scheme, measured zerovelocity duration from the ground reaction sensors is used to reset the accumulated integration errors from accelerometers and gyroscopes in position calculation. With the described system, an average position error of 4 m is achieved at the end of half-hour walks.

Individual Muscle Contributions To The Axial Knee Joint Contact Force During Normal Walking, Kotaro Sasaki, Richard R. Neptune

Mechanical and Biomedical Engineering Faculty Publications and Presentations

Muscles are significant contributors to the high joint forces developed in the knee during human walking. Not only do muscles contribute to the knee joint forces by acting to compress the joint, but they also develop joint forces indirectly through their contributions to the ground reaction forces via dynamic coupling. Thus, muscles can have significant contributions to forces at joints they do not span. However, few studies have investigated how the major lower-limb muscles contribute to the knee joint contact forces during walking. The goal of this study was to use a muscle-actuated forward dynamics simulation of walking to identify …

Material Modeling And Analysis For The Development Of A Realistic Blast Headform, S. G. M. Hossain

Department of Mechanical and Materials Engineering: Dissertations, Theses, and Student Research

Blast traumatic brain injury (BTBI) has become an important topic of study because of the increase of such incidents, especially due to the recent growth of improvised explosive devices (IEDs). This thesis discusses a project in which laboratory testing of BTBI was made possible by performing blast loading on experimental models simulating the human head. Three versions of experimental models were prepared – one having a simple geometry and the other two having geometry similar to a human head. For developing the head models, three important parts of the head were considered for material modeling and analysis – the skin, …

Pre-Swing Deficits In Forward Propulsion, Swing Initiation And Power Generation By Individual Muscles In Hemiparetic Walking, Carrie L. Peterson, Allison Kinney, Steven A. Kautz, Richard R. Neptune

Mechanical and Aerospace Engineering Faculty Publications

Clinical studies of hemiparetic walking have shown pre-swing abnormalities in the paretic leg suggesting that paretic muscle contributions to important biomechanical walking subtasks are different than those of non-disabled individuals. Three-dimensional forward dynamics simulations of two representative hemiparetic subjects with different levels of walking function classified by self-selected walking speed (i.e., limited community=0.4–0.8 m/s and community walkers=>0.8 m/s) and a speed-matched control were generated to quantify individual muscle contributions to forward propulsion, swing initiation and power generation during the pre-swing phase (i.e., double support phase proceeding toe-off). Simulation analyses identified decreased paretic soleus and gastrocnemius contributions to forward propulsion …

Relationships Between Muscle Contributions To Walking Subtasks And Functional Walking Status In Persons With Post-Stroke Hemiparesis, Allison Kinney, Carrie L. Peterson, Steven A. Kautz, Richard R. Neptune

Mechanical and Aerospace Engineering Faculty Publications

Walking speed is commonly used to predict stroke severity and assess functional walking status (i.e., household, limited community and community walking status) post-stroke. The underlying mechanisms that limit walking speed (and functional walking status by extension) need to be understood to improve post-stroke rehabilitation. Previous experimental studies have shown correlations between paretic plantarflexor output during the pre-swing phase and walking speed and suggest that the paretic hip flexors can compensate in some hemiparetic subjects. Modeling and simulation studies of healthy walking have shown that the ankle plantarflexors, soleus (SOL) and gastrocnemius (GAS), and uniarticular hip flexors (IL) are essential contributors …

Fracture Of Bone Using Microindentation, Séverine Vennin

Department of Engineering Mechanics: Dissertations, Theses, and Student Research

Osteoporosis is a current disease which is especially of concern to post-menopausal women. It is characterized by a decrease of bone density and an increase in the risk of fracture. Interest in the fracture mechanisms with respect to the underlying biological structure of the bone is of great interest to researchers in this field. In this thesis, a new method based on microindentation on rat femurs was developed to determine the relation between the viscoelastic and the fracture properties of bone. The main goal is to measure the viscoelastic properties by using a dynamic mechanical analysis indentation method and then …

Application Of A Bayesian Inference Method To Reconstruct Short-Range Atmospheric Dispersion Events, Inanc Senocak

Mechanical and Biomedical Engineering Faculty Publications and Presentations

In the event of an accidental or intentional release of chemical or biological (CB) agents into the atmosphere, first responders and decision makers need to rapidly locate and characterize the source of dispersion events using limited information from sensor networks. In this study the stochastic event reconstruction tool (SERT) is applied to a subset of the Fusing Sensor Information from Observing Networks (FUSION) Field Trial 2007 (FFT 07) database. The inference in SERT is based on Bayesian inference with Markov chain Monte Carlo (MCMC) sampling. SERT adopts a probability model that takes into account both positive and zero-reading sensors. In …

Intelligibility Of Electrolarynx Speech Using A Novel Actuator, Brian Madden, Mark Nolan, Ted Burke, James Condron, Eugene Coyle

Conference Papers

During voiced speech, the larynx provides quasi-periodic acoustic excitation of the vocal tract. Following a laryngectomy, some people speak using an electrolarynx which replaces the excitatory function of the absent larynx. Drawbacks of conventional electrolarynx designs include the buzzing monotonic sound emitted, the need for a free hand to operate the device, and difficulty experienced by many laryngectomees in adapting to its use. Despite these shortcomings, it remains the preferred method of speech rehabilitation for a substantial minority of laryngectomees. In most electrolarynxes, mechanical vibrations are produced by a linear electromechanical actuator, the armature of which percusses against a metal …

Effect Of Loading Condition On Traction Coefficient Between Shoes And Artificial Turf Surfaces, Seth M. Kuhlman, Michelle B. Sabick, Ronald Pfeiffer, Benjamin Cooper, Jackie Forhan

Mechanical and Biomedical Engineering Faculty Publications and Presentations

Background. The interaction between a shoe and a turf surface is highly complex and difficult to characterize. Over the three decades since artificial turf was introduced, researchers have attempted to understand the traction caused by the interaction. However, some of the methodologies used for traction measurements have not capitalized on advances in currently available technology for testing and most testing conditions have not simulated realistic physiological loads.

Method of Approach. To assess the effect of test condition on traction results, the newly designed TurfBuster testing device was used to collect traction data on FieldTurf™ brand artificial turf under varying conditions. …

An Investigation Of Humeral Stress Fractures In Racing Thoroughbreds Using A 3d Finite Element Model In Conjunction With A Bone Remodeling Algorithm, Ryan James Moore

Master's Theses

The humerus of a racing horse Thoroughbred is highly susceptible to stress fractures at a characteristic location as a result of cyclic loading. The propensity of a Thoroughbred to exhibit humeral fracture has made equines useful models in the epidemiology of stress fractures. In this study, a racing Thoroughbred humerus was simulated during training using a 3D finite element model in conjunction with a bone remodeling algorithm. Nine muscle forces and two contact forces were applied to the 3-dimensional finite element model, which contains four separate load cases representing fore-stance, mid-stance, aft-stance, and standing. Four different training programs were incorporated …

An Analytical Model For Rotator Cuff Repairs, A. Aurora, Jorge E. Gatica, Antonie J. Van Den Bogert, J. A. Mccarron, Kathleen A. Derwin

Mechanical Engineering Faculty Publications

Background

Currently, natural and synthetic scaffolds are being explored as augmentation devices for rotator cuff repair. When used in this manner, these devices are believed to offer some degree of load sharing; however, no studies have quantified this effect. Furthermore, the manner in which loads on an augmented rotator cuff repair are distributed among the various components of the repair is not known, nor is the relative biomechanical importance of each component. The objectives of this study are to (1) develop quasi-static analytical models of simplified rotator cuff repairs, (2) validate the models, and (3) predict the degree of load …

Nonequilibrium Thermodynamics Modeling Of Coupled Biochemical Cycles In Living Cells, Yaşar Demirel

Yaşar Demirel Publications

Living cells represent open, nonequilibrium, self organizing, and dissipative systems maintained with the continuous supply of outside and inside material, energy, and information flows. The energy in the form of adenosine triphosphate is utilized in biochemical cycles, transport processes, protein synthesis, reproduction, and performing other biological work. The processes in molecular and cellular biological systems are stochastic in nature with varying spatial and time scales, and bounded with conservation laws, kinetic laws, and thermodynamic constraints, which should be taken into account by any approach for modeling biological systems. In component biology, this review focuses on the modeling of enzyme kinetics …

Towards Supervised Autonomous Task Completion Using An In Vivo Surgical Robot, Jason J. Dumpert

Department of Mechanical and Materials Engineering: Dissertations, Theses, and Student Research

Laparoscopy is a minimally invasive alternative to traditional abdominal surgery. Unlike traditional surgery, a laparoscopic procedure can be completed using small incisions. The use of these small incision results in reduced pain to the patient, shorter recovery times, and less trauma to skin, muscle and other tissues. However, these benefits to the patient are offset by the increased difficulty to the surgeon performing the procedure. These difficulties include reduced dexterity, reduced perception, and longer procedure times. The use of small in vivo robotic devices in minimally invasive surgery is one possible solution to these problems. The movement of these devices …

Influence Of Towing Force Magnitude On The Kinematics Of Supramaximal Sprinting, David A. Clark, Seth Kuhlman, Michelle B. Sabick, Ronald P. Pfeiffer, Nicole A. Knigge

Mechanical and Biomedical Engineering Faculty Publications and Presentations

The purpose of this study was to determine the influence of towing force magnitude on the kinematics of supramaximal sprinting. Ten high school and collegiate aged track and field athletes ran 60m maximal sprints under 5 different conditions: non-towed (NT), Tow A (2.0% body weight), Tow B (2.8%BW), Tow C (3.8%BW), and Tow D (4.7%BW). Three-dimensional kinematics of a 4-segment model of the right side of the body were collected starting at the 35m point of the trial. Significant differences were observed in stride length (SL) and horizontal velocity of the center of mass (VH) during Tow C and Tow …

Mechanical Simulation Of Articular Cartilage Based On Experimental Results, Kevin Matthew Stewart

Master's Theses

Recently, a constituent based cartilage growth finite element model (CGFEM) was developed in order to predict articular cartilage (AC) biomechanical properties before and after growth. Previous research has noted limitations in the CGFEM such as model convergence with growth periods greater than 12 days. The main aims of this work were to address these limitations through (1) implementation of an exact material Jacobian matrix definition using the Jaumann-Kirchhoff (J-K) method and (2) quantification of elastic material parameters based upon research findings of the Cal Poly Cartilage Biomechanics Group (CPGBG). The J-K method was successfully implemented into the CGFEM and exceeded …

A Real-Time, 3-D Musculoskeletal Model For Dynamic Simulation Of Arm Movements, Edward K. Chadwick, Dimitra Blana, Antonie J. Van Den Bogert, Robert F. Kirsch

Mechanical Engineering Faculty Publications

Neuroprostheses can be used to restore movement of the upper limb in individuals with high-level spinal cord injury. Development and evaluation of command and control schemes for such devices typically require real-time, ldquopatient-in-the-looprdquo experimentation. A real-time, 3-D, musculoskeletal model of the upper limb has been developed for use in a simulation environment to allow such testing to be carried out noninvasively. The model provides real-time feedback of human arm dynamics that can be displayed to the user in a virtual reality environment. The model has a 3-DOF glenohumeral joint as well as elbow flexion/extension and pronation/supination and contains 22 muscles …

The Relationships Between Muscle, External, Internal And Joint Mechanical Work During Normal Walking, Kotaro Sasaki, Richard R. Neptune, Steven A. Kautz

Mechanical and Biomedical Engineering Faculty Publications and Presentations

Muscle mechanical work is an important biomechanical quantity in human movement analyses and has been estimated using different quantities including external, internal and joint work. The goal of this study was to investigate the relationships between these traditionally used estimates of mechanical work in human walking and to assess whether they can be used as accurate estimates of musculotendon and/or muscle fiber work. A muscle-actuated forward dynamics walking simulation was generated to quantify each of the mechanical work measures. Total joint work (i.e. the time integral of absolute joint power over a full gait cycle) was found to underestimate total …

Rapid-Response Urban Cfd Simulations Using A Gpu Computing Paradigm On Desktop Supercomputers, Inanc Senocak, Julien C. Thibault, Matthew Caylor

Mechanical and Biomedical Engineering Faculty Publications and Presentations

In the event of chemical or biological (CB) agent attacks or accidents, first-responders need hazard prediction data to launch effective emergency response action. Accurate and timely knowledge of the wind fields in urban areas is critically important to identify and project the extent of CB agent dispersion to determine the hazard-zone. In their 2008 report (GAO-08-180), U.S. Government Accountability Office has reported that first responders are limited in their ability to detect and model hazardous releases in urban environments. The current set of modeling tools for contaminant dispersion in urban environments rely on empirical assumptions with diagnostic equations (Wang et …

Ultrasonic Angioplasty: Assessing The Risk Of Arterial Perforation, Mark Wylie, Garrett Mcguinness, Graham Gavin

Conference Papers

Atherosclerosis is a cardiovascular disease that effects large and medium muscular arteries (such as coronary and iliac) and also large elastic arteries (such as aorta) [1]. It causes thickening of the arterial wall and over time can result in a completely blocked artery or chronic total occlusion (CTO). While the majority of atherosclerotic lesions can be attempted by typical Percutaneous Transluminal Coronary Angioplasty (PTCA) such as balloon and stent implantation, calcified CTOs are often problematic as they do not lend themselves to be accessed by the guidewire which is required to implant the balloon and stent. Excessive guidewire pushing force …