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Articles 1 - 4 of 4
Full-Text Articles in Biology and Biomimetic Materials
Nature-Inspired Material Strategies Towards Functional Devices, Sayantan Pradhan
Nature-Inspired Material Strategies Towards Functional Devices, Sayantan Pradhan
Theses and Dissertations
Naturally sourced, renewable biomaterials possess outstanding advantages for a multitude of biomedical applications owing to their biodegradability, biocompatibility, and excellent mechanical properties. Of interest in this dissertation are silk (protein) and chitin (polysaccharide) biopolymers for the fabrication of functional biodevices. One of the major challenges restricting these materials beyond their traditional usage as passive substrate materials is the ability to combine them with high-resolution fabrication techniques. Initial research work is directed towards the fabrication of micropatterned, flexible 2D substrates of silk fibroin and chitin using bench-top photolithographic techniques. Research is focused on imparting electrochemical properties to silk proteins using conducting …
Design, Manufacture, And Structural Dynamic Analysis Of A Biomimetic Insect-Sized Wing For Micro Air Vehicles, Jose Enrique Rubio
Design, Manufacture, And Structural Dynamic Analysis Of A Biomimetic Insect-Sized Wing For Micro Air Vehicles, Jose Enrique Rubio
LSU New Orleans Theses and Dissertations
The exceptional flying characteristics of airborne insects motivates the design of biomimetic wing structures that can exhibit a similar structural dynamic behavior. For this purpose, this investigation describes a method for both manufacturing a biomimetic insect-sized wing using the photolithography technique and analyzing its structural dynamic response. The geometry of a crane fly forewing (family Tipulidae) is acquired using a micro-computed tomography scanner. A computer-aided design model is generated from the measurements of the reconstructed scanned model of the insect wing to design the photomasks of the membrane and the venation network required for the photolithography procedure. A composite …
Fabrication Of Flexible, Biofunctional Architectures From Silk Proteins, Ramendra K. Pal
Fabrication Of Flexible, Biofunctional Architectures From Silk Proteins, Ramendra K. Pal
Theses and Dissertations
Advances in the biomedical field require functional materials and processes that can lead to devices that are biocompatible, and biodegradable while maintaining high performance and mechanical conformability. In this context, a current shift in focus is towards natural polymers as not only the structural but also functional components of such devices. This poses material-specific functionalization and fabrication related questions in the design and fabrication of such systems. Silk protein biopolymers from the silkworm show tremendous promise in this regard due to intrinsic properties: mechanical performance, optical transparency, biocompatibility, biodegradability, processability, and the ability to entrap and stabilize biomolecules. The unique …
Artificial Alveolar-Capillary Membrane On A Microchip, Keith Male
Artificial Alveolar-Capillary Membrane On A Microchip, Keith Male
Materials Engineering
A microfluidic device was synthesized out of polydimethyl siloxane (PDMS) to simulate the structure of the alveolar-capillary interface of the human lung. Soft lithography techniques were used to build a mold structure out of SU-8 epoxy at heights ranging from 30µm to 110 µm on a silicon substrate, with the 70 µm structure working the best. A mixture of 10:1 Sylgard 184 elastomer was then cast using the mold, and cured at a temperature of 80oC. For the porous membrane, the PDMS was spun on at 6000rpm for 30 seconds using a spin coater to produce a membrane …