Open Access. Powered by Scholars. Published by Universities.®
Biology and Biomimetic Materials Commons™
Open Access. Powered by Scholars. Published by Universities.®
- Discipline
-
- Medicine and Health Sciences (3)
- Nanomedicine (3)
- Nanotechnology (3)
- Biomaterials (2)
- Biomedical Engineering and Bioengineering (2)
-
- Medical Specialties (2)
- Analytical, Diagnostic and Therapeutic Techniques and Equipment (1)
- Applied Mechanics (1)
- Ceramic Materials (1)
- Diseases (1)
- Mechanical Engineering (1)
- Medical Sciences (1)
- Molecular, Cellular, and Tissue Engineering (1)
- Musculoskeletal Diseases (1)
- Musculoskeletal, Neural, and Ocular Physiology (1)
- Nanoscience and Nanotechnology (1)
- Oncology (1)
- Orthopedics (1)
- Polymer and Organic Materials (1)
- Therapeutics (1)
- Translational Medical Research (1)
- Wounds and Injuries (1)
- Keyword
-
- Acropora cervicornis (1)
- Aragonite (1)
- Bioimaging (1)
- Biomaterials (1)
- Biomedical Therapeutics (1)
-
- Bone Tissue Regeneration (1)
- Cancer (1)
- Cerium (1)
- Chronic wound healing (1)
- Core-shell nanoparticles (1)
- Hardness (1)
- Material doping (1)
- Nanomedicine (1)
- Nanoparticle mediated therapy (1)
- Nanotechnology (1)
- Raman spectra (1)
- Reactive Oxygen Species (1)
- Regenerative Medicine (1)
- Superparamagnetic (1)
- Theranostics (1)
- Tissue Engineering (1)
- Uniaxial strength (1)
- Wound Healing (1)
Articles 1 - 5 of 5
Full-Text Articles in Biology and Biomimetic Materials
Fabricating Silver-Ceria Polymer Nanocomposite Scaffolds For Biomedical Therapeutic Applications, Shreya S. Pawar
Fabricating Silver-Ceria Polymer Nanocomposite Scaffolds For Biomedical Therapeutic Applications, Shreya S. Pawar
Honors Undergraduate Theses
Improper healing of bone fractures and limited regeneration of bone following bone tumor resection remain a prevalent complication worldwide. Long-term effects of this include joint instability, limited movement, and arthritis. Bone infections (osteomyelitis), reactive oxygen species (ROS) generation via excessive inflammation, and underlying conditions such as osteoporosis can contribute to suboptimal bone tissue regeneration. ROS accumulation stimulates osteoblast apoptosis, while promoting osteoclast differentiation. These processes inhibit mineralization and osteogenesis. Conventional therapeutics involve the utilization of drugs and bone grafts. However, these approaches pose limitations and can result in subsequent complications. Microbial infections, ROS accumulation, and excessive inflammations are factors that …
Effect Of Metal Ions On The Reactive Oxygen Species Scavenging Capabilities Of Cerium Oxide For Biological Applications, Agastya Mittal
Effect Of Metal Ions On The Reactive Oxygen Species Scavenging Capabilities Of Cerium Oxide For Biological Applications, Agastya Mittal
Honors Undergraduate Theses
Ceria nanoparticles' capabilities to defend cells against oxidative stress through superoxide dismutase activity are well-documented. Ceria nanoparticles demonstrate a ratio between 3+/4+ oxidative states on the surface of the particles to exhibit oxygen vacancies, a feature that allows these particles to scavenge Reactive Oxygen Species (ROS) in times of Oxidative Stress. Oxidative stress arises from many wounds in the body, such as wounds in the skin, and can have significant impacts on the health of an individual. Even when receiving treatment for the skin wound, ROS can circulate from around the wound, be generated from an imbalance …
Synthesis And Characterization Of Multifunctional Cerium Oxide Containing Nanoparticles For Biomedical Applications, Ishaan Patel
Synthesis And Characterization Of Multifunctional Cerium Oxide Containing Nanoparticles For Biomedical Applications, Ishaan Patel
Honors Undergraduate Theses
This study presents the synthesis and comprehensive characterization of a novel core-shell nanoparticle composed of a maghemite (γ-Fe2O3) core and a europium-doped cerium oxide (EuCNP) shell, developed for potential use in cancer theranostics. Using a co-precipitation method, Fe2O3–EuCNP core-shell nanoparticles were synthesized and compared against control samples of CNPs, EuCNPs, and Fe2O3. A variety of characterization techniques, including UV-Vis spectroscopy, fluorescence spectroscopy, TEM, XRD, XPS, DLS, TGA, and DSC confirmed the successful synthesis of core-shell architecture and europium doping. Moreover, Fe2O3–EuCNPs demonstrating strong colloidal …
Silver Doped Nanoceria (Agcnp) Integrated Silk Scaffold For Chronic Wound Healing, Architha K. Venkatesan
Silver Doped Nanoceria (Agcnp) Integrated Silk Scaffold For Chronic Wound Healing, Architha K. Venkatesan
Honors Undergraduate Theses
Chronic wound healing can be seriously impeded by the formation of biofilms, infections, peri-wound edema, hematoma, osteomyelitis, and the formation of reactive oxidative species (ROS). We hypothesize that a scaffold created from Silver-Doped Nanoceria (AgCNP) embedding silk can be beneficial to aid the wound healing process, inhibit inflammation and prevent microorganisms from forming a biofilm over the wound. Current wound healing methods such as intradermal injections are not advantageous to use since they can cause unwanted responses elsewhere in the body other than the wound site. Silk, however, has a positive impact on the wound healing effect and can be …
Raman Spectroscopy Of The Skeleton Of The Coral Acropora Cervicornis, Zachary C. Shepard
Raman Spectroscopy Of The Skeleton Of The Coral Acropora Cervicornis, Zachary C. Shepard
Honors Undergraduate Theses
Coral reefs are an important element of marine ecosystem that are critical to maintain a healthy environment. Unfortunately, in recent years coral reefs are doing poorly and many in parts of the ocean are simply dying. Therefore, study of coral’s structural response to external loads could answer what will happen with their structures, while they exhibit different types of loading. Therefore, the proposition of using in-situ micro-Raman spectroscopy to study skeletons of Acropora cervicornis was used. Coral skeleton samples I subjected to mechanical loading studied their vibrational properties by exciting the material with 532nm visible light. A uniaxial compressive load …