Materials Science and Engineering Commons^™

Air-Jet Bioprinting Of Stem Cell-Encapsulated Alginate Micro-Droplets For Organoid Biomanufacturing, Mirabella B. Stump

Electronic Theses and Dissertations

Biomanufactured 3D-organoids show promise for modeling and treating various conditions, particularly insulin-dependent diabetes mellitus (type-1 diabetes). Pancreatic islet organoids serve as sustainable sources of insulin-producing β-cells, potentially restoring insulin regulation in patients and providing a long-term solution for diabetes. Hydrogel droplet printing is an emerging technique in regenerative medicine due to its advantageous tunability and biocompatibility; however, challenges of consistency, quality control, and scalability persist. To address these issues, we developed a novel air-jetting based droplet bioprinting system for the generation of monodispersed alginate micro-droplets. The objective of this project was to incorporate human induced pluripotent stem cells (hiPSCs) into …

Moisture Effects On Visible Near-Infrared And Mid-Infrared Soil Spectra And Strategies To Mitigate The Impact For Predictive Modeling, Francis Hettige Chamika Anuradha Silva

Theses and Dissertations

Instrumental disparities and soil moisture are two of the key limitations in implementing spectroscopic techniques in the field. This study sought to address these challenges through two objectives. The first objective was to assess Visible-near infrared (VisNIR) and mid-infrared (MIR) spectroscopic approaches and explore the feasibility of transferring calibration models between laboratory and portable spectrometers. The second objective addressed the challenge of soil moisture and its impact on spectra. The portable spectrometers demonstrated comparable performance to their laboratory-based counterparts in both regions. Spiking with extra-weight, was the most effective calibration transfer method eliminating disparities between instruments. The samples were rewetted …

Molecular Control Of Triplet-Pair Spin Polarization And Its Optoelectronic Magnetic Resonance Probes, Obadiah G. Reid, Justin C. Johnson, Joel D. Eaves, Niels H. Damrauer, John E. Anthony

Chemical and Materials Engineering Faculty Publications

Preparing and manipulating pure magnetic states in molecular systems are the key initial requirements for harnessing the power of synthetic chemistry to drive practical quantum sensing and computing technologies. One route for achieving the requisite higher spin states in organic systems exploits the phenomenon of singlet fission, which produces pairs of triplet excited states from initially photoexcited singlets in molecular assemblies with multiple chromophores. The resulting spin states are characterized by total spin (quintet, triplet, or singlet) and its projection onto a specified molecular or magnetic field axis. These excited states are typically highly polarized but exhibit an impure spin …

Design And Characterization Of A Novel Eef2k Degrader With Potent Therapeutic Efficacy Against Triple-Negative Breast Cancer, Changxin Zhong, Rongfeng Zhu, Ting Jiang, Sheng Tian, Xiaobao Zhao, Xiaoya Wan, Shilong Jiang, Zonglin Chen, Rong Gong, Linhao He, Jin-Ming Yang, Na Ye, Yan Cheng

Markey Cancer Center Faculty Publications

Dysregulated eEF2K expression is implicated in the pathogenesis of many human cancers, including triple-negative breast cancer (TNBC), making it a plausible therapeutic target. However, specific eEF2K inhibitors with potent anti-cancer activity have not been available so far. Targeted protein degradation has emerged as a new strategy for drug discovery. In this study, a novel small molecule chemical is designed and synthesized, named as compound C1, which shows potent activity in degrading eEF2K. C1 selectively binds to F8, L10, R144, C146, E229, and Y236 of the eEF2K protein and promotes its proteasomal degradation by increasing the interaction between eEF2K and the …

Engineered Biomass-Derived Carbon Adsorbents For Targeted Contaminant Remediation From Aqueous Environments, Suraj Venkat Pochampally

UNLV Theses, Dissertations, Professional Papers, and Capstones

Porous carbon adsorbents like biochar (BC) are produced from waste biomasses like wood chips, animal litter, nut shells, dried grass, etc. to be used in a multitude of applications like gas capture, soil amendment, water treatment, electrode materials, etc. In water treatment, carbon-based adsorbents have been mainly used to physically or chemically adsorb contaminants depending on the adsorption mechanism. However, BCs in their raw state do not have the capability of absorbing high amounts of contaminants and need to be activated/ modified for the pore network to broaden and adsorb the contaminants with better efficiency.

The scope of this dissertation …

Characterization Of Interlayer Laser Shock Peening During Fused Filament Fabrication Of Polylactic Acid (Pla), Fabien Denise

Department of Mechanical and Materials Engineering: Dissertations, Theses, and Student Research

The field of additive manufacturing (AM) has gained a significant amount of popularity due to the increasing need for more sustainable manufacturing techniques and the adaptive development of complex product geometries. The problem is that AM parts routinely exhibit flaws or weaknesses that affect functionality or performance. Over the years, surface treatments have been developed to compensate certain flaws or weaknesses in manufactured products. Combining surface treatments with the modularity of additive manufacturing could lead to more adaptable and creative improvements of product functions in the future. The current work evaluates the feasibility of pursuing a new research axis in …

Constructing Carbon-Encapsulated Nifev-Based Electrocatalysts By Alkoxide-Based Self-Template Method For Oxygen Evolution Reaction, En-Hui Ma, Xu-Po Liu, Tao Shen, De-Li Wang

Journal of Electrochemistry

The development of green and sustainable water-splitting hydrogen production technology is beneficial to reducing the over-reliance on fossil fuels and realizing the strategic goal of "carbon neutral". As one of the half reactions for water splitting, oxygen evolution reaction has suffered the problems of sluggish four-electron transfer process and relatively slow reaction kinetics. Therefore, exploring efficient and stable catalysts for oxygen evolution reaction is of critical importance for water-splitting technology. Metal alkoxides are a series of compounds formed by the coordination function of metal ions with alcohol molecules. Metal alkoxides possess the double advantages of organic materials and inorganic materials, …

The Effects Of Engineering Summer Camps On Middle And High School Students’ Engineering Interest And Identity Formation: A Multi-Methods Study, Timothy Robinson, Adam Kirn, Jenny Amos, Indira Chatterjee

Journal of Pre-College Engineering Education Research (J-PEER)

This multi-methods study explores changes in engineering interest and identity of middle and high school students (n = 79) attending introductory-level engineering summer camps at a large western land grant university. Middle school is a critical time when student interest, identity, and subsequently career choice begin to emerge and hence it is important that at this age students are given accurate information about engineering majors in college and future career opportunities in engineering. Data were collected over a period of two years in six summer camps. Three separate populations of middle and high school students participated in the summer …

Novel Castor Oil/Water/Ethanol Pickering Emulsions Stabilized By Magnetic Nanoparticles And Magnetically Controllable Demulsification, Mohammad J. Hasan, Peng Chen, Neithan Dominick, Erick S. Vasquez, Esteban E. Ureña-Benavides

Chemical and Materials Engineering Faculty Publications

A novel castor oil/water/ethanol Pickering emulsion, stabilized by magnetic nanoparticles (NPs), was developed to allow on-demand demulsification by an external magnetic field for the extraction of ethanol from aqueous solution using the castor oil. The emulsion was stabilized by Fe3O4-coated cellulose nanocrystals (CNC@Fe3O4) and lignin-coated Fe3O4 NPs (lignin@Fe3O4). The stability of the emulsions was investigated at various castor oil to ethanol-water ratios (50/50 and 70/30), various NP concentrations, and ethanol concentrations in the aqueous phase. The magnetically controlled demulsification ability of the emulsions was investigated by using a permanent magnet. The results showed that the 70/30 emulsions were more stable …

Surface Modifications Of Lini0.96Co0.02Mn0.02O2 With Tungsten Oxide And Phosphotungstic Acid, Gang Zhao, Zheng-Liang Gong, Yi-Xiao Li, Yong Yang

Journal of Electrochemistry

With the rapid development of electric vehicles, enormous demands are made for higher energy density, better cycling performance and lower cost of lithium-ion batteries (LIBs). As an important high capacity cathode material for LIBs, the high nickel layered oxide material LiNi_0.8Co_0.1Mn_0.1O₂(NCM811) can reach an energy density of 760 Wh·kg^-1. The ultra-high nickel ternary positive electrode material (LiNi_1-x-yCo_xMn_yO₂, x ≥ 0.90) has a specific capacity of more than 210 mAh·g^-1, and can realize higher energy density. Besides, an ultra-high nickel material …

Preparation And Electrocatalytic Performance Of Feni-Cop/Nc Bifunctional Catalyst, Si-Miao Liu, Jing-Jiao Zhou, Shi-Jun Ji, Zhong-Sheng Wen

Journal of Electrochemistry

Rechargeable zinc-air batteries have gradually attracted much attention worldwide due to their high capacity, high energy density and low price. Oxygen reduction reaction (ORR) and oxygen evolution reaction (OER) correspond to the charging and discharging processes in rechargeable zinc-air battery, respectively. At present, commercial Pt/C and IrO₂ catalysts hinder the large-scale application of zinc-air batteries due to low reserves, high prices and poor stability. Therefore, exploring high performance, low cost and high stability with dual functional catalysts is important for the development of rechargeable zinc-Air batteries. The metal-organic frameworks (MOFs) have high specific surface area, structural stability, good catalytic …

Effect Of Fire Flame On Some Mechanical Properties Of Self-Compacting Concrete, Haider Sadiq M. Ali, Nabeel A-M. Albayati, Basman R. Mohammed, Adil M. Jabbar

Al-Esraa University College Journal for Engineering Sciences

This paper presents an experimental investigation of the effect of fire flame on self-compacting concrete. The experimental program included casting cylinder and prism concrete specimens for compressive strength, modulus of elasticity, modulus of rupture, and concrete density tests. The specimens are exposed to fire flame at 800 ºC approximately for 2 hours or 6 hours. Then the specimens were cooled either in a fast or slow manner. Test results show that the compressive strength was reduced by about (54 - 61)% for fire exposure of 6 hours and by (27 - 37)% for 2 hours of exposure and cooled slowly …

Manual Preparation Of Eyeglasses Based On Corneal Topographical Images For Keratoconus Patients, Bassma Sabah Majeed, Faiz F. Mustafa, Nebras H. Ghaeb

Al-Esraa University College Journal for Engineering Sciences

keratoconus (KCN) is a non-inflammatory, progressive thinning process of the cornea. It is considered one of the advanced biomechanical changes on the corneal surface, and methods of treatment in late cases are special designed contact lenses or surgical intervention. The objective of this paper is to customize the standard eyeglass lens in a way so that it fits with the abnormal shape and changes of the surface of the cornea of a patient suffering from KCN disease.The proposed method here, based on manual scratching of the external surface of the standard eyeglass lens under supervising of an expert optometrist, where …

Age-Friendly Educational Buildings Primary Schools In Kerbala - A Case Study, Anwar Fadhil Hussein, Ibrahim Jawad Kadhim

Al-Esraa University College Journal for Engineering Sciences

The concept of age-friendly societies has gained international attention among researchers, policy makers, and community organizations since the World Health Organization launched the Friendly Communities Project in 2006, to address challenges in some countries, as these challenges affect all aspects of society, and the educational environment represents an important joint of those joints, being the environment that is the most effective and influential in shaping human behavior. The age stage that is most affected and capable of learning and shaping behavior is of importance, which is the childhood stage. Therefore, the research focused on school buildings, as they represent an …

The Role Of Enhancing Interaction With The Natural Environment In Achieving Social Interaction For Children In Orphanage Institutions, Shamael M. W. Al Dabbagh, Zainab Khalid Rashad Al Khafaji

Al-Esraa University College Journal for Engineering Sciences

The child deprived of family care is considered the child most in need of attention and care. When the orphan child enters a new environment for him, it is obvious that he feels alienated, isolated, and loses the sense of interaction and communication with society. The research sees the possibility of mitigating this feeling by enhancing interaction with the natural environment within the internal spaces of the orphanage building and at the neighborhood level. In order to solve the research problem, the research adopted a hypothesis stating that "interaction with the natural environment enhances the achievement of social interaction for …

The Role Of Academic Competitions In Promoting Architectural Education: Tamayouze Excellence Award In Iraqi Architectural Education - Case Study, Nairy Mugardich Krikor, Anwar Subhi Ramadan

Al-Esraa University College Journal for Engineering Sciences

The importance of architectural competitions has emerged in finding the best designs, upgrading and architectural advancement in both practice and thinking. Architectural competitions have become intellectual meetings that contribute to stimulating self-learning and encouraging creativity. They act as an educational tool that leads to competition, giving motivation to the development of skills and learning, in a way that enhances the integration between architectural theory and practical practice for both engineers and architecture students. The research was concerned with studying the effective role of academic competitions in architectural education as one of the ways to improve teaching and learning, and to …

Analysis And Mitigation Of Cyber-Attacks Targeting Infrastructures Operated By Iot Systems, Raja Salih Mohammed Hasan, Nadia Mahmood Ali, Ihsan Jabbar Hasan

Al-Esraa University College Journal for Engineering Sciences

Numerous countries have a high impact on providing the planet with critical infrastructures offering very important services employed in different fields such as water resources management, public services, power grids, telecoms, commercials, and transportation. The increasing solutions in IoT systems made it possible to exploit internet connection services for supporting the critical infrastructures. The latest are being targeted by various types of cyber-attacks due to the advancement in internet services. Therefore, improving the security systems and the ways to detect the threats is highly required. Meanwhile, protecting the critical infrastructures from hostile cyber-attacks is of high significance. This article examines …

Reliability Assessment Model Of Network Operating System Based On Convolution Neural Network, Jamal N. Hasoon, Sarah S. Qasim, Mohammed A. Alshomali, Jane J. Stephan

Al-Esraa University College Journal for Engineering Sciences

The paper's subject is one of the points of fundamental significance in improving the development of complex computer systems is the effect of errors since their probability of occurrence in a widely distributed system is exceptionally high. Thus, the computer system must be dependable and provide comprehensive support for fault tolerance, fault detection, signal recovery mechanisms, failure prediction, etc. The goal is to develop a way to evaluate the reliability of the Red Hat Linux operating system utilizing data sets of system failures obtained from system injection with error reports using the Fault Injection Benchmarking and Reliability) FIBR( (for a …

Investing Traditional Architecture That Fulfills The Supreme Human Needs With Its Spiritual Dimension In Reconstruction / The Architecture Of Old Mosul City, A Case Study, Sinan Mohammad Talee Al-Saffar, Anwar Subhi Ramdan Al - Qaraghuli

Al-Esraa University College Journal for Engineering Sciences

Architecture has sought since time immemorial to meet multiple human needs, starting from the basic physiological needs for human survival, psychological needs (social and individual) to needs related to human progress, such as taking into account the aesthetic and spiritual aspects, which represent the highest levels of those needs, through a set of design aspects and characteristics. This research is based on the study of the spiritual dimension of higher human needs in general that architecture seeks to meet, by studying that in the architecture of traditional cities, in particular, to enhance architectural knowledge with regard to the importance of …

The Role Of Algorithms In Formulating The Architectural Formation, Ghada Ghalib Abdul Wahab, Younis Mahmood M. Salem

Al-Esraa University College Journal for Engineering Sciences

Algorithms are mathematical processes that provide step-by-step instructions for solving a specific problem. They are commonly used in computer science and other technical fields to automate processes and solve complex problems. One great application of algorithms is the generation of shapes. Algorithms can be used to create complex shapes and patterns that are difficult or impossible to create manually. We will explore how algorithms can be used as a mechanism to generate shapes by adopting the Voronoi algorithm because it provides a wide environment for creativity through new intellectual processes that may not occur at all in the human mind …

The Detection Of Android Malwares Using The Features Selection Technique, Farah Rafid Salman, Amer Abdulmajeed Abdulrahman

Al-Esraa University College Journal for Engineering Sciences

The use of Android smartphones has been rising quickly as Internet-based services gain more popularity and develop. The Android operating system's enormous popularity has drawn malware attacks on these devices. It is difficult and ineffective to detect malware versions with features that modify their behavior in order to avoid detection by machine learning (ML) techniques. Effective feature selection plays a crucial role in detecting malware characteristics and reduces the dimensionality of a large dataset by removing unnecessary features that are not useful and keeping those relevant features that increase classification accuracy and detection rate. This helps to solve the problems …

A Review Of Polymer – Particles Composite Materials, Ismail Ibrahim Marhoon, Ayad Abbood Abdul Al-Hassan, Mohammed Ali Abdulrehman

Al-Esraa University College Journal for Engineering Sciences

In several engineering applications traditional materials are replacedby composite materials. Filled composite materials consist of the continuousmatrix and the filling particles. The primary purpose of introducing inorganicsolid particles into polymers is to essentially increase mechanical and physicalproperties. The wear properties of polymer composite can be changed to agreater degree by modifying the process of preparing the filled compositematerials. In the present review, a large-scale research has been conductedon the effect of wear on the composites of polymers. The effect of filler onthe polymer composites wear behavior has been thoroughly explained

Ability Of Replacing The Steel Strands By Cfrp In Pre-Stressed Concrete Girders: Art Review, Ahmed Salim Edan, Wael Shawky Abdulsahib

Al-Esraa University College Journal for Engineering Sciences

Fiber-reinforced polymer (FRP) composites are the modern,trustworthy alternatives to steel tendons and rebars. The bulk of currentresearch is devoted to establishing the feasibility of incorporating carbonfibre-reinforced polymer (CFRP) into reinforced concrete girders byevaluating the strength and reliability of CFRP and concrete components.In order to improve fatigue and corrosion resistance, CFRPs are crucial.Comparing reinforced prestressed concrete bridge girders strengthenedwith conventional steel reinforcement to those reinforced with CFRPs offersthe possibility of greatly increasing service life. Also widely researchedand used in bridge engineering as a corrosion-resistant substitute for steelreinforcement is CFRP composite material. The use of carbon fiber-reinforcedplastic (CFRP) reinforcement for prestressing concrete …

A Review Article On The Performance Based Seismic Design Of Structures, Reem Hatem Ahmed, Sahar Elaiwi, Shelan Hameed Ameen

Al-Esraa University College Journal for Engineering Sciences

For the most part, seismic design builds complex structural systems using the same small number of essential structural components as non-seismic design projects. Based on the building regulations, structures are frequently designed to "withstand" the largest earthquake with a given likelihood that is projected to happen at their location. This means that by avoiding structures from collapsing, the number of fatalities must be maintained to a minimal. Seismic design involves knowing the many failure modes regarding a structure and giving it the right stiffness, strength, ductility, and layout for ensuring that these modes do not take place. In this essay, …

Corrosion Case Study On Pipeline, Kangze Ren

Corrosion Research

The Kashagan pipeline leaks were likely caused by sulfur stress corrosion cracking, a combined corrosion mechanism developed by the presence of high pressure, the high level of hydrogen sulfide(the main "ingredient" of sour gas), and poor metallurgical choice. Improper welding and poor metallurgical examination were blamed for causing the leaking issue. The purpose of the current review is to raise the alarm about the inappropriate corrosion management of Kashagan oil production and its societal and environmental consequences.

Evolution Of Glassy Carbon Derived From Pyrolysis Of Furan Resin, Josh Kemppainen, Ivan Gallegos, Aaron Krieg, Jacob R. Gissinger, Kristopher E. Wise, Margaret Kowalik, Julia A. King, S. Gowtham, Adri Van Duin, Gregory Odegard

Michigan Tech Publications

Glassy carbon (GC) material derived from pyrolyzed furan resin was modeled by using reactive molecular dynamics (MD) simulations. The MD polymerization simulation protocols to cure the furan resin precursor material are validated via comparison of the predicted density and Young's modulus with experimental values. The MD pyrolysis simulations protocols to pyrolyze the furan resin precursor is validated by comparison of calculated density, Young's modulus, carbon content, sp carbon content, the in-plane crystallite size, out-of-plane crystallite stacking height, and interplanar crystallite spacing with experimental results from the literature for furan resin derived GC. The modeling methodology established in this work can …

Cellulose Materials For Drug Delivery Applications, Reham Mohamed

Mechanical Engineering Theses

Non-healing wounds are a growing global public health concern due to inadequate or ineffective therapeutic products available. Cellulose-based biopolymers are attractive wound dressing materials due to their biocompatibility, biodegradability, non-toxicity, and cost-effectiveness. This study aims to design and fabricate solid dosage formulations using carboxymethyl cellulose (CMC) and ethyl cellulose (EC) to facilitate multi-stage releases of phenytoin (PHT) and tetracycline hydrochloride (TCH) from plain carriers, fibers/films composites, and layer-by-layer fiber composites. Results from in vitro drug release assays demonstrated a time-dependent release up to 8 hours from PHT-loaded EC fibers, while TCH-loaded CMC films exhibited a rapid release within 5 minutes. …

Hydrophobicity Optimization Of Cathode Catalyst Layer For Proton Exchange Membrane Fuel Cell, Hao-Jie Chen, Mei-Hua Tang, Sheng-Li Chen

Journal of Electrochemistry

Hydrophobicity of the cathode catalyst layers (CCLs) crucially determines the performance of proton exchange membrane fuel cells (PEMFCs) by affecting the transports of oxygen and liquid water. In this regard, polytetrafluoroethylene (PTFE) is usually used as a hydrophobic additive to facilitate the oxygen and water transports in CCLs. So far, there remains lacking systematic effort to optimize the addition methods of PTFE in CCLs and the mechanisms behind. In this work, the effects of the approaches for PTFE addition and the distribution of PTFE on the mass transport of oxygen and the proton conduction in CCLs were studied by using …

Challenges In Optimization For The Performance On Sustainability Dimensions In Reverse Logistics Social Responsibility, Sumarsono Sudarto, Katsuhiko Takahashi, Mochammad Dewo

Makara Journal of Technology

Reverse logistics social responsibility is preferred as the most acceptable solution for addressing the challenges in stakeholders’ debate regarding social responsibility in supply chains because it involves as many actors as possible in the supply chain to perform social responsibility to achieve sustainability. This paper explores the challenges in achieving optimal policies in sustainability dimensions for collection and recycling facilities in reverse logistics. Sustainability dimensions include economic, environmental, and social aspects. The reverse logistics is modeled on System Dynamics, and a simplified statistical analysis using a contour chart is employed in numerical experiments. Results show a narrow area of optimal …

Investigating The Rheological Behavior Of A Simple Yield Stress Fluid Under Shear Flows, Francesco Accetta

Theses

Many soft materials display unique and complex rheological behavior characterized by a transition from a solid-like to a fluid-like state upon the application of a force that exceeds the threshold to flow, known as the yield stress. Yield stress fluids are found in a wide range of commonly encountered materials including microgels, emulsions, and foams, and have been widely studied by rheologists over the last several decades. Carbopol is a popular polymeric microgel system as it displays simple, non-thixotropic rheological behavior and is typically seen as an ideal yield stress fluid. Previous research has demonstrated the reproducible behavior of shear …