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Full-Text Articles in Biomedical
Design And Characterization Of Thermal Inkjet Bioprinted Constructs For The Treatment Of Diabetic Foot Ulcers And Other Wound Healing Impaired Conditions, Luis Horacio Solis
Design And Characterization Of Thermal Inkjet Bioprinted Constructs For The Treatment Of Diabetic Foot Ulcers And Other Wound Healing Impaired Conditions, Luis Horacio Solis
Open Access Theses & Dissertations
Tissue engineering (TE) is a multidisciplinary practice focused on developing patient-specific constructs to repair, regenerate, or replace injured tissues and organs. One biofabrication process that has gained tremendous momentum in this field is bioprinting. Most, if not all bioprinting modalities embody the same principles of heat and shear due to mechanical forces or friction as cells are forced through narrow orifices. While it is important to examine the interaction between host and implanted constructs, it is also crucial to understand the direct effects that these bioprinting technologies have on cells before embedding them into TE applications.
The purpose of this …
The Anti-Angiogenic Effects Of Sparstolonin B, Henry Rhodes Bateman
The Anti-Angiogenic Effects Of Sparstolonin B, Henry Rhodes Bateman
Theses and Dissertations
Sparstolonin B (SsnB) is a novel bioreactive compound isolated from Sparganium stoloniferum, an herb historically used in Traditional Chinese Medicine as an anti-tumor agent. SsnB has demonstrated anti-inflammatory properties, inhibiting Toll-like receptor mediated inflammation in isolated macrophages and in mice. Angiogenesis, the process of new capillary formation from existing blood vessels, is dysregulated in many pathological disorders, including atherosclerosis, diabetic retinopathy, and tumor growth. The goal of the project was to investigate the anti-angiogenic effects of SsnB.
The first part of the project utilized in vitro functional assays to study how SsnB affected endothelial cells. SsnB inhibited endothelial cell tube …