Biomedical Commons^™

Design And Parametric Testing Of A Transimpedance Amplifier For Low-Power Biomedical Applications, Stanlon Tan, William Chung, Brandon Wu

Electrical Engineering

This project developed and evaluated an optical sensing system for detecting changes associated with glucose concentration. The system combined a laser-diode, cuvette sample holder, photodiode, resistive-feedback transimpedance amplifier, high-resolution analog-to-digital converter, and microcontroller. Parametric testing evaluated the effects of input current and feedback resistance on transimpedance gain, output range, and linearity. Firmware was developed to configure the ADC, average repeated conversions, monitor measurement variation, convert raw digital counts into voltage using a source-meter calibration equation, and compare sample measurements with a water reference. A cuvette enclosure maintained alignment between the laser-diode, sample, and photodiode while reducing external optical interference. Testing …

2-Channel Eeg Neurofeedback System, Tim Erwin, Donna Nikjou, Sebastian Turkewitz

Electrical Engineering

This work describes the design of an EEG-based neurofeedback system which provides users with real-time feedback on their level of focus or relaxation. By analyzing the spectral content of the brain activity measured via scalp electrodes, focus and relaxation levels can be quantified. Based on these measurements, live feedback in the form of moving bar graphs is provided to users, allowing them to gain awareness of their mental-state and more efficiently learn how to consciously relax or focus. This project covers the design of the system, including amplification and filtering stages, digitization, and signal processing. The system interfaces with a …

Cardio Trainer, Levi Rash, Cristian Rodriguez

Electrical Engineering

The Cardio Trainer Device is a wearable device that guides the user through a physical exercise based on the user’s heartbeat measurements. Users interface with the device via a wearable band. The band determines the heartbeat of the user in real time and, using that reading, gives the user verbal instructions to optimize their workout. These verbal instructions then serve to control the physical exertion of the user and are delivered through an audio device. Users input personal physical metrics to the Cardio Trainer Device that tailor the performance of the device in a manner of ways: rate of instruction, …

Diy Cell Incubator, Hayden James Jeanor

Electrical Engineering

The purpose of creating a cell Incubator is for the development of cell and tissue production in laboratory settings. Large scale research projects and the medical community grow cells for various reasons, including experiments and creating tissue for patients. However, they cannot simply depend on growing cells in a petri dish that sit on a rack at room temperature. To grow heathy cells in the fastest way possible, they use cell incubators. Cell incubators create an atmosphere within the incubation bay that is designed to promote cell growth. The three main components that need to be constantly regulated, using a …

Smart Bottle Ble Integration, Joshua M. Rizzolo

Electrical Engineering

In 1975, four percent of children aged five to nineteen were categorized as overweight or obese. As of 2016, this figure climbed above 18 percent [1]. Researchers at California Polytechnic State University San Luis Obispo (Cal Poly) want to investigate the effect of overeating in early childhood on later childhood obesity. This research requires collecting feeding pattern data on infants, which proves challenging. Parents cannot be relied on to regularly collect clean data due to factors including work schedule, multitasking, and general exhaustion. Thus, we have developed a tool to automatically collect data on feeding frequency and duration, as well …

Bicep Muscle Rep Counter With Semg, Matthew Max Garcia

Electrical Engineering

The Bicep Muscle Rep Counter with SEMG is a device that was made to develop three repetition thresholds or difficulty levels from a fully-flexed bicep brachii muscle and signal to the user when consequent bicep muscle contractions pass said thresholds or levels. This device can be used when performing a bicep-focused movement or when generally flexing the bicep muscle. Essentially, this device serves to make sure each repetition of a muscle contraction passes a percentage value calculated from the electrical activity outputted from a max contraction.

The device is not designed for and does not produce data for muscle growth, …

Remote Healthcare Monitoring Using Wearable Iot Devices And Cloud Services, Mohammad Abdellatif, Menatalla Abdel-Gawad, Manar Usama, Haidy Hesham, Omar Ibrahim

Electrical Engineering

With the strain on healthcare infrastructure and healthcare workers due to the ongoing COVID'19 pandemic, the need for novel ways to simplify the interaction between patients and physicians has increased. The aim is mainly to reduce face-to-face interactions and free more time and resources for those who urgently need it. This paper presents a Telemedicine system which can be used as an alternative method to a doctor's visit. The proposed system is considered as an interface that remotely connects the patient and the doctor. The system regularly measures and uploads readings from the patient to a database which the doctor …

Verification Of A Digital Microfluidics Platform, Karanpartap Singh

Electrical Engineering

The electrowetting effect describes the change in contact angle between a solid surface and electrolyte in response to an applied electric potential difference. Given a planar array of individually-actuated electrodes, electrowetting can be used to transport, mix, and separate picoliter to microliter-sized droplets of liquid on a dielectric layer. Applications of this phenomenon range from lab-on-a-chip and other microfluidic devices to liquid lenses capable of altering their topology and focus within milliseconds.

This project extends prior work simulating the dependence of droplet velocity on actuation voltage and demonstrates observed physics on a physical platform. The simulation portion of this project …

Smart Motor Syringe System, Connor Wilson

Electrical Engineering

In this document a proof-of-concept design is developed and implementation to showcase the latest development in an ongoing effort to produce a series of automated syringe pumps.

Portable Ventilator, Bradley C. Weeks, Jack W. Brewer, Sanders Sanabria

Electrical Engineering

The current COVID-19 pandemic has heavily impacted the healthcare system in the United States and elsewhere. The need for patients to have access to a hospital with a ventilator along with a shortage of ventilators for recovery and at-home care as a result of minimal hospital vacancy for patients has been greatly stressed. The presented problem is both an unmet demand and supply of portable and effective ventilators. Existing ventilators have many shortcomings that should be addressed: size, weight, cost, and complexity of current ventilators confines users to stay in a medical facility whilst being monitored by professionals. This both …

Smart Motor Syringe System, Conard Chan, Jenny Chiao

Electrical Engineering

Syringe pumps are widely used in many research applications especially in the applications that need precise control. Today most medical research utilizes syringes to control the fluid being pumped to the experiment objects. In most cases microscopic or nano-scopic motion control is required to acquire optimal results, such application includes purification of DNA/RNA from contaminants[1]. The high precision required to control the syringe pump makes it difficult to perform manually. This paper focuses on the design of an intelligent syringe pump motor control system to achieve reliable and precise control for biomedical experiments. This project improves medical research quality with …

Telemedicine: An Iot Based Remote Healthcare System., Mohammad Abdellatif, Walaa Mohamed

Electrical Engineering

This paper proposes a remote healthcare system which is referred to as Telemedicine. Telemedicine is a platform that establishes a connection be-tween the patient and the doctor. This platform belongs to the internet of medical things (IoMT) by enabling multiple medical sensors to connect to a server either using multiple communication technologies such as Wi-Fi, Bluetooth or GSM technologies. The system collects data from several sensors and sends them using one of the aforementioned technologies using an Arduino Board, while the inter-face is made with matlab and C#. Additionally, a comparative study between the three communications technologies used to connect …

Electrocardiographic (Ecg) Biometric Identification, Ryan Morosa, Charbel Ghantous

Electrical Engineering

Electrocardiography (ECG) is being used a lot more in biometrics for applications where protection of privacy is important. Other methods like facial recognition can be falsified by using different colored contacts to manipulate identification. For this reason, ECG is a viable option for biometric identification since it relies solely on the heartbeat to classify characteristics of an individual. The Pan-Tompkins method was used for feature extraction, and both ELM and correlation were used for classification. ELM through MATLAB achieved an average accuracy of 85%. Correlation achieved an average accuracy of 89.2%.

Eeg Midi Controller, Jack Ellison, Eric Bettencourt

Electrical Engineering

One of the greatest challenges for aspiring musicians is the amount of practice and commitment required to become fluent in a traditional instrument. Taken a step further, individuals who have impaired motor skills may be incapable of even executing the physical demands required to practice one. While this device does not create notes directly from a user's brain waves, exploring and designing EEG based musical hardware capable of using a person’s thoughts to control musical devices could pave the way for greater advances. It can also open many doors into psycho-acoustic research, treating the mind's response to hearing music and …

Blood Glucose Predictor, Jessica Patterson

Electrical Engineering

For my senior project, I perform data analysis using statistical methods to determine body metrics that correlate with blood glucose levels. Working with Dr. Tina Smilkstein, I take repeat measurements from 6 different volunteers to establish trends in bodily metric data. The data taken includes weight, body fat, pulse rate, VO2, blood glucose, blood pressure, hours slept, and quality of sleep. Using these values, I use the program MiniTab to view results.

A few examples of correlations with blood glucose found in this project are:

• Systolic blood pressure for females had a regression line of 124.0 -0.3366*Blood Pressure. This indicates …

Portable Electrocardiogram Device And Signal Processing Design, Ryan F. Blaalid

Electrical Engineering

Full 12-lead electrocardiogram (ECG) measurements require inconvenient and time consuming adhesive electrode placement. This project proposes a design for a Bluetooth based ECG for remote patient measurement. The device is designed to measure up to 6-leads and utilizes 5 dry (non-adhesive) electrodes to accomplish this. The device delivers the ECG data to the user’s mobile smart phone and can then be sent to the patient’s doctor for analysis. Since the contact of the dry electrodes to the skin is not perfect, low-frequency noise called baseline wandering is introduced. A signal processing technique borrowed from image processing called morphological filtering is …

Eeg Classification Using Residual Neural Networks, Eren Esener

Electrical Engineering

There is a growing desire to understand the EEG (electroencephalogram) signals related with brain activities. In order to analyze EEG signals, they first must be measured by sensors, which induces a lot of noise; then these signals are classified to understand the intended actions. In many cases a neural network is used as the algorithms for classification. A residual neural network (ResNet) is an artificial neural network (ANN) of a kind that are related with the pyramidal cells in the cerebral cortex. The goal of this work is to investigate the viability of ResNets for classifying EEG signals for hand …

Telemedicine: An Iot Application For Healthcare Systems, Mohammad Abdellatif, Walaa Mohamed

Electrical Engineering

Telemedicine is the abstract term used to define medical services delivered through Information Technology and Telecommunications. With the growing advancements in the field of data mining, pattern recognition, expert systems, and image processing, the motivation of such a technology has increased. This allowed Telemedicine to be a stable solution especially because people are starting to trust the system more for its higher accuracy. This paper proposes a Telemedicine platform between the patient and the doctor. This platform belongs to the internet of medical things (IoMT) by enabling multiple medical sensors to connect to a server either using Wi-Fi, Bluetooth or …

Portable 6 Lead 4 Electrode Ekg, Cody Magnuson, Wes Archbold

Electrical Engineering

This project focused on designing a small, portable, 6 lead 4 electrode electrocardiogram (EKG) machine with enough accuracy and resolution to successfully diagnose clinical issues. The electrical design used to measure signals originating from the heart can be broken up into three stages. The first stage is the human device interface. Next, is the analog block that filters out common mode noise and conditions the signal for digital encoding using instrumentation amplifiers, a right leg circuit, high pass, low pass, and an amplifier. This circuit filters all frequencies above and below the frequency band of meaningful data (1-160Hz), rejects signals …

Ecg Classification Using Adaptive Neuro-Fuzzy Inference System, Jason N. Rivera, Kelsey C. Rodriguez

Electrical Engineering

ECG classification using Adaptive Neuro-Fuzzy Inference System (ANFIS), sponsored by Professor Yu, involves the diagnosis of six cardiovascular conditions by analyzing one single neural network. Today’s ECG signal instrumentation does not have the ability to characterize cardiovascular diseases without a doctor’s complete evaluation and diagnosis. Our project gives a promising solution to the inability in the current market’s ECG signal instrumentation to correctly evaluate and diagnose cardiovascular diseases. ECG signal reportings is a non-invasive process that will lead to many more applications of advanced signal processing and data analysis/diagnosis of cardiovascular diseases. The inputs to the ANFIS are annotations of …

Wax Bee Gone: A Safe, Effective Solution To Ear Wax Removal, Robert G. Shenon, Shanvir S. Dhinsa

Electrical Engineering

This project sought to combine conventional methods such as scraping and water pressure to removal ear wax, but with electronic automation to removal the potential for human error as much as possible. Through the use of a 9V battery, and Arduino microcontroller, DC motors, and other circuitry, this project has developed a prototype for a device that can properly remove ear wax without any discomfort or risk to the user. Much of this project involved learning how to properly manipulate and provide the necessary power requirements DC motors from an Arduino and a 9V battery. Additionally, creating a 3D printed …

Active Charge Balancing For Cardiac Stimulation, Maci Miri

Electrical Engineering

Worldwide, there are about 3 million people who have pacemakers, with 10,000 new implantations of ICD’s each month. [heart.org] Due to the gravity and importance of the function that ICD’s provide, these devices must be extremely reliable and highly effective. However, because of the high tolerances of IC manufacturing, stimulation circuits for pacemakers may be slightly unmatched and over time, may have a net DC charge applied to the tissues in the heart. Extra charge pumped into body tissues is dangerous for the patient’s health; the pH of the tissue can be raised and corrosion of the stimulating electrodes may …

A Stroke Therapy Brace Design, Evan Kirkbride

Electrical Engineering

Victims of stroke often have difficulty with rehabilitation. With limited movement on their affected arm, patients often do not want to move much for physical therapy. In this project, we design a robotic brace that helps stroke patients move their arm more effectively in a reaching or pulling motion. By giving patients more movement in their affected arm than they would have otherwise, patients gain more from rehabilitation. The brace also adapts to the patient’s needs, providing more inclination or resistance as needed for their physical therapy. This kind of therapy engages patients rather than relying on their likely dwindled …

Exertion Control, Travis Taylor

Electrical Engineering

Current wearable fitness devices give the user after-the-fact fitness data, but little real-time feedback. Exertion Control, a new wearable device, continuously measures the user’s heart rate, creates a heart rate target, and helps the user reach it. This project completes the senior design and master’s thesis requirements and contains two milestones. The senior design product continuously measures the wearer’s heart rate and logs it with a user-friendly interface. This data models the heart’s exertion response and recovery response. The master’s thesis device refines the closed control loop with the user to give them a workout optimized to fit their needs.

An Iris Authentication System Based On Artificial Neural Networks, Brenden Velu

Electrical Engineering

An iris authentication system verifies the authenticity of a person based on their iris features. The iris features are extracted through wavelet transform of the isolated iris from modified iris images. A level 5 wavelet decomposition is performed on the images, and the resulting low-frequency wavelet coefficients represent the inputs to the artificial neural network. The artificial neural network reads these features as inputs, and classifies each set of inputs according to their target identity. This authentication system currently classifies up to 10 people. The irises used for classification represent ideal situations with minimum eyelash and eyelid interference.

Permanent Magnet Display System, Xenia Leon Rodriguez

Electrical Engineering

Pacemakers can malfunction when exposed to high magnetic fields. This becomes especially problematic for patients with pacemakers who need MRI scans as MRI machines can subject the pacemaker to damaging magnetic fields. St.Jude Medical, one of the leading biotech companies, is working to make their pacemakers MRI-safe. In order to test their MRI-safe pacemaker designs, they need an automated test apparatus that will collect and report the magnetic field the pacemaker is being exposed to. This report describes the design of such a test system that reads the Tesla intensity the pacemaker is exposed to and wirelessly transmits the data …

Large Dynamic Range Amplifier Plus Adc, Ted Hsueh

Electrical Engineering

Nerve and muscle signal sampling proves difficult because of the large difference in magnitudes. Muscle signals loom a hundred or even a thousand times bigger and can hide the nerve signals. The Large Dynamic Range Amplifier plus Analog to Digital Converter (ADC) allows one device to retrieve both muscle and nerve signal information. The device has two parts: the ability to take high-resolution data from tenths of microvolts to several millivolts and filter out environmental noise, such as 60 Hz of electrical power lines or electro galvanic signals. This gives the ability to read muscle and nerve signals using one …

St. Jude Medical - R&D Robot For Sensor Testing, Andrew Chanul Kim, Stanley Logan Laszczyk, Edgar Nava, Nathan Gall

Electrical Engineering

No abstract provided.

Laminar Flow Hood System Design, Sophie Schneider

Electrical Engineering

In 2011 health care costs for transplants were over 12 billion dollars in the United States for evaluation, procurement, facilities use, physicians, and post-transplant check-ups. In 2012 burns hospitalized 40,000 people and over 17,000 people received organ transplants. Sadly, the number of organ donors greatly lags the number of people on the transplant waiting list and the gap has widened over the decades. While preventative health care is extremely important, researching tissue engineering (TE) to treat patients in fatal condition provides alternatives for replacing or repairing a variety of damaged tissue. These alternative treatments can considerably reduce the supply-demand gap …

Energy Harvesting Of Human Kinetic Movement, David Marusiak, Julia Carrillo

Electrical Engineering

Development of kinetic energy scavenging applications from the human body necessitates additional research to assist in designating a mounting position for a potential device. A data acquisition system adequately provides a parametric average power comparison among four locations on the body (waist, upper arm, hand, and calf) for both a male and female subject. Experimentally, the hand-held device provided the highest average power. Thus, subsequent investigation at set speeds provides further analysis of the output’s characteristically linear behavior. The physical energy-harvesting device features a plastic tube casing wrapped with the stationary coiled wire through which a neodymium magnet oscillates. While …