Biomedical Commons^™

Implementing Associative Learning Using Neuromorphic Robot, Vinay Kumar Pillalamarri

Dissertations, Master's Theses and Master's Reports

Associative learning, a key cognitive process seen across the animal kingdom, enables organisms to form connections between stimuli and adapt their behaviors based on past experiences. A particularly powerful example is fear conditioning, where animals learn to associate a neutral stimulus with an aversive one, allowing them to predict and avoid potential threats. Inspired by this mechanism, this project implements associative learning on an unmanned ground vehicle (UGV) to develop adaptive behavior through neuromorphic principles. Utilizing Nengo for neural modeling, the UGV learns to associate visual (red color) and tactile (vibration) stimuli through Hebbian learning, a biologically inspired synaptic adaptation …

Novel Bayesian Neural Networks And Uncertainty Quantification Of Computational Mechanics Models, Ponkrshnan Thiagarajan

Dissertations, Master's Theses and Master's Reports

Computational and data-driven models suffer from a wide range of uncertainties that impact the reliability of such models. Given the exponential proliferation of machine learning models in real-world systems, establishing a degree of confidence in their predictions becomes paramount. Reliability in predictions takes on utmost significance in domains such as autonomous driving, medical image analysis, etc., where human lives are involved, and inaccuracies in predictions could lead to disastrous outcomes. For these reasons, comprehending and quantifying uncertainties in computational and data-driven models is of utmost importance. A number of techniques have been developed to quantify uncertainties in machine learning models. …

The Application Of Leaky Wave Antennas For Medical Hyperthermia Treatment And Beamformer In Fmcw Automotive Radar Systems, Masoud Sarabi

Dissertations, Master's Theses and Master's Reports

Thousands of years ago human discovered that if a slice of amber is rubbed against fur, it would absorb light-weight objects. Hundreds of years after that the ancient people figured out that there are actually two different characteristics of attraction and repulsion. Another 2000 years passed when human discovered that these two wonders of nature, magnetism and electricity are actually linked together like the two sides of the same coin. Since then, in the early 19th century great huge achievements were made in antennas and propagation by scientists such as Hans Christen Oersted, Heinrich Hertz, Alexander Popov and Marconi. Since …

Antibacterial Properties Of Mussel-Inspired Polydopamine Coatings Prepared By A Simple Two-Step Shaking-Assisted Method, Pegah Kord Fooroshani, Elizabeth Polega, Kevin Thomson, Mohammad Saleh Akram Bhuiyan, Rattapol Pinnaratip, Mikhail Trought, Chito E. Kendrick, Yuesheng Gao, Kathryn Perrine, Lei Pan, Bruce P. Lee

Michigan Tech Publications, Part 1

A simple two-step, shaking-assisted polydopamine (PDA) coating technique was used to impart polypropylene (PP) mesh with antimicrobial properties. In this modified method, a relatively large concentration of dopamine (20 mg ml⁻¹) was first used to create a stable PDA primer layer, while the second step utilized a significantly lower concentration of dopamine (2 mg ml⁻¹) to promote the formation and deposition of large aggregates of PDA nanoparticles. Gentle shaking (70 rpm) was employed to increase the deposition of PDA nanoparticle aggregates and the formation of a thicker PDA coating with nano-scaled surface roughness (RMS = 110 …

Estimation Of Multi-Directional Ankle Impedance As A Function Of Lower Extremity Muscle Activation, Lauren Knop

Dissertations, Master's Theses and Master's Reports

The purpose of this research is to investigate the relationship between the mechanical impedance of the human ankle and the corresponding lower extremity muscle activity. Three experimental studies were performed to measure the ankle impedance about multiple degrees of freedom (DOF), while the ankle was subjected to different loading conditions and different levels of muscle activity. The first study determined the non-loaded ankle impedance in the sagittal, frontal, and transverse anatomical planes while the ankle was suspended above the ground. The subjects actively co-contracted their agonist and antagonistic muscles to various levels, measured using electromyography (EMG). An Artificial Neural Network …

Implantable Wireless Sensor Networks: Application To Measuring Temperature For In Vivo Detection Of Infections, Praharsh Madappaly Veetil

Dissertations, Master's Theses and Master's Reports

It is has been proven that infection in the body cause a local temperature increase due to localized inflammation. Therefore, a method to provide early diagnostic or long-term tracking of this infection will provide great benefits to patients with diabetic foot ulcers or sickle cell disease, and those receiving hemodialysis where they suffer from a weakened immune system. The goal of this project is to develop an implantable wireless temperature sensor based on a wireless sensor network system for monitoring infections in situ. The analog signals from the thermistors are digitized and wirelessly transmitted to a computer with an ez430-rf2500 …

A Wireless, Passive Sensor For Measuring Temperature At Orthopedic Implant Sites For Early Diagnosis Of Infections, Salil Sidharthan Karipott

Dissertations, Master's Theses and Master's Reports

Sensorized implants with embedded wireless, passive temperature sensors were developed for early detection of implant-associated infections. The operation principle of the sensor is based on the hypothesis that infections can lead to an increase in local temperature prior to the rise of body temperature. The sensor was an inductive capacitive (LC) circuit that has been used for monitoring of different parameters wirelessly, often in difficult to access environments. The sensor was fabricated on to an interference screw, which is used for tendon and ligament reconstruction surgeries. In this project, a sensorized interference screw was designed and fabricated by accommodating an …

Hardware Design And Integration And Software Programming For Optical Elastography, Nima Taherkhani

Dissertations, Master's Theses and Master's Reports

The elastic and viscoelastic properties of skin are a reflection of its health. Measurement of these elastic properties can be used as the indicator of various pathologies. The measurement concept in our works is to mechanically stimulate the skin with a low frequency pneumatic force using non-invasive means of deflecting the skin and use laser speckle to study the elasticity of the skin.

The goal of this work was to develop a setup for in vivo optical elastography of skin. This setup includes an electro-mechanical device which is able to deliver a sinusoidal pneumatic stimulus equivalent to 10 grams of …