Open Access. Powered by Scholars. Published by Universities.®

Computer Engineering Commons

Open Access. Powered by Scholars. Published by Universities.®

Articles 361 - 390 of 496

Full-Text Articles in Computer Engineering

Sample Investigating System And Method Of Use, Martin M. Liphardt, Thomas E. Tiwald, Blaine D. Johs, Jeffery S. Hale, Craig M. Herzinger, Steven E. Green, Ping He, Ronald A. Synowicki, John A. Woollam Apr 2012

Sample Investigating System And Method Of Use, Martin M. Liphardt, Thomas E. Tiwald, Blaine D. Johs, Jeffery S. Hale, Craig M. Herzinger, Steven E. Green, Ping He, Ronald A. Synowicki, John A. Woollam

Department of Electrical and Computer Engineering: Faculty Publications

A spectroscopic system for adjusting spacing between an adjacent source/detector as a unit, and a sample, and a reflecting means for directing an incident beam which reflects from said sample back onto said sample and then into the detector along a locus which is in a plane of incidence that is offset from that of the incident beam, or directly from the reflecting means into the detector, including means for reducing reflections of a beam of electromagnetic from the back of a sample, including methodology of use.


Optimally Enhanced Optical Emission In Laser-Induced Breakdown Spectroscopy By Combining Spatial Confinement And Dual-Pulse Irradiation, L. B. Guo, B. Y. Zhang, X. N. He, C. M. Li, Y. S. Zhou, T. Wu, J. B. Park, X. Y. Zeng, Yongfeng Lu Jan 2012

Optimally Enhanced Optical Emission In Laser-Induced Breakdown Spectroscopy By Combining Spatial Confinement And Dual-Pulse Irradiation, L. B. Guo, B. Y. Zhang, X. N. He, C. M. Li, Y. S. Zhou, T. Wu, J. B. Park, X. Y. Zeng, Yongfeng Lu

Department of Electrical and Computer Engineering: Faculty Publications

In laser-induced breakdown spectroscopy (LIBS), a pair of aluminum-plate walls were used to spatially confine the plasmas produced in air by a first laser pulse (KrF excimer laser) from chromium (Cr) targets with a second laser pulse (Nd:YAG laser at 532 nm, 360 mJ/pulse) introduced parallel to the sample surface to re-excite the plasmas. Optical emission enhancement was achieved by combing the spatial confinement and dual-pulse LIBS (DP-LIBS), and then optimized by adjusting the distance between the two walls and the interpulse delay time between both laser pulses. A significant enhancement factor of 168.6 for the emission intensity of the …


Current-Based Diagnosis For Gear Tooth Breaks In Wind Turbine Gearboxes, Dingguo Lu, Xiang Gong, Wei Qiao Jan 2012

Current-Based Diagnosis For Gear Tooth Breaks In Wind Turbine Gearboxes, Dingguo Lu, Xiang Gong, Wei Qiao

Department of Electrical and Computer Engineering: Faculty Publications

Gearbox faults constitute a significant portion of all faults and downtime in wind turbines (WTs). Current-based gearbox fault diagnosis has significant advantages over traditional vibration-based techniques in terms of cost, implementation, and reliability. This paper derives a mathematical model for a WT drive train consisting of a twostage gearbox and a permanent magnet (PM) generator, from which the characteristic frequencies of gear tooth breaks in generator stator current frequency spectra are clearly identified. A adaptive signal resampling algorithm is proposed to convert the variable fault characteristic frequencies to constant values for WTs running at variable speeds. A fault detector is …


Energy Efficiency In Multiaccess Fading Channels Under Qos Constraints, Deli Qiao, Mustafa Cenk Gursoy, Senem Velipasalar Jan 2012

Energy Efficiency In Multiaccess Fading Channels Under Qos Constraints, Deli Qiao, Mustafa Cenk Gursoy, Senem Velipasalar

Department of Electrical and Computer Engineering: Faculty Publications

In this article, transmission over multiaccess fading channels under quality-of-service (QoS) constraints is studied in the low-power and wideband regimes. QoS constraints are imposed as limitations on the buffer violation probability. The effective capacity, which characterizes the maximum constant arrival rates in the presence of such statistical QoS constraints, is employed as the performance metric. A two-user multiaccess channel model is considered, and the minimum bit energy levels and wideband slope regions are characterized for different transmission and reception strategies, namely time-division multiple-access (TDMA), superposition coding with fixed decoding order, and superposition coding with variable decoding order. It is shown …


Matching And Funneling Light At The Plasmonic Brewster Angle, Christos Argyropoulos, Giuseppe D'Aguanno, Nadia Mattiucci, Neset Akozbek, Mark J. Bloemer, Andrea Alu Jan 2012

Matching And Funneling Light At The Plasmonic Brewster Angle, Christos Argyropoulos, Giuseppe D'Aguanno, Nadia Mattiucci, Neset Akozbek, Mark J. Bloemer, Andrea Alu

Department of Electrical and Computer Engineering: Faculty Publications

The ultrabroadband impedance matching of metallic gratings at the plasmonic Brewster angle [A. Al`u et al., Phys. Rev. Lett. 106, 123902 (2011)] is analyzed here in several realistic scenarios and configurations, and in the case of nonmonochromatic excitation. This phenomenon is the analogy of the well-known Brewster transmission for dielectric slabs but, when applied to plasmonic gratings, has the remarkable property of funneling and concentrating light within subwavelength slits. We analyze here how the presence of absorption and of realistic substrates and/or superstrates may influence the phenomenon, its beamwidth and angular selectivity, and its overall performance in the case …


A Low-Cost, Reliable, High-Throughput System For Rodent Behavioral Phenotyping In A Home Cage Environment, Steven A. Parkison, Jay D. Carlson, Tammy R. Chaudoin, Traci A. Hoke, A. Katrin Schenk, Evan H. Goulding, Lance C. Pérez, Stephen J. Bonasera Jan 2012

A Low-Cost, Reliable, High-Throughput System For Rodent Behavioral Phenotyping In A Home Cage Environment, Steven A. Parkison, Jay D. Carlson, Tammy R. Chaudoin, Traci A. Hoke, A. Katrin Schenk, Evan H. Goulding, Lance C. Pérez, Stephen J. Bonasera

Department of Electrical and Computer Engineering: Faculty Publications

Inexpensive, high-throughput, low maintenance systems for precise temporal and spatial measurement of mouse home cage behavior (including movement, feeding, and drinking) are required to evaluate products from large scale pharmaceutical design and genetic lesion programs. These measurements are also required to interpret results from more focused behavioral assays. We describe the design and validation of a highly-scalable, reliable mouse home cage behavioral monitoring system modeled on a previously described, one-ofa- kind system [1]. Mouse position was determined by solving static equilibrium equations describing the force and torques acting on the system strain gauges; feeding events were detected by a photobeam …


Nonlinear Plasmonic Cloaks To Realize Giant All-Optical Scattering Switching, Christos Argyropoulos, Pai-Yen Chen, Francesco Monticone, Giuseppe D'Aguanno, Andrea Alu Jan 2012

Nonlinear Plasmonic Cloaks To Realize Giant All-Optical Scattering Switching, Christos Argyropoulos, Pai-Yen Chen, Francesco Monticone, Giuseppe D'Aguanno, Andrea Alu

Department of Electrical and Computer Engineering: Faculty Publications

Here we extend the reach of Fano resonant coupling by combining this concept with cloaking and plasmonic resonances in a single nonlinear nanoparticle, in order to realize giant all-optical scattering nanoswitches controlled by moderate pumping intensities. We show that a core-shell nonlinear plasmonic particle may be designed to abruptly switch from being completely cloaked to being strongly resonant, with up to a 40 dB cross-sectional difference. Self-tunable optical cloaks and resonant scatterers are envisioned for use as efficient all-optical switches and nanomemories.


Boosting Optical Nonlinearities In E-Near-Zero Plasmonic Channels, Christos Argyropoulos, Pai-Yen Chen, Giuseppe D'Aguanno, Nadar Engheta, Andrea Alu Jan 2012

Boosting Optical Nonlinearities In E-Near-Zero Plasmonic Channels, Christos Argyropoulos, Pai-Yen Chen, Giuseppe D'Aguanno, Nadar Engheta, Andrea Alu

Department of Electrical and Computer Engineering: Faculty Publications

The anomalous transmission properties of zero-permittivity ultranarrow channels are used to boost Kerr nonlinearities and achieve switching and bistable response for moderate optical intensities. Strong field enhancement, uniform all along the channel, is a typical feature of ε-near-zero supercoupling and is shown to be particularly suited to enhance nonlinear effects. This is obtained by designing narrow apertures at cutoff in a plasmonic screen. We show that this nonlinear mechanism can significantly outperform nonlinearities in traditional Fabry-P´erot resonant gratings.


Broadband Brewster Transmission Through 2d Metallic Gratings, Khai Q. Le, Christos Argyropoulos, Nadia Mattiucci, Giuseppe D'Aguanno, Mark J. Bloemer, Andrea Alu Jan 2012

Broadband Brewster Transmission Through 2d Metallic Gratings, Khai Q. Le, Christos Argyropoulos, Nadia Mattiucci, Giuseppe D'Aguanno, Mark J. Bloemer, Andrea Alu

Department of Electrical and Computer Engineering: Faculty Publications

Recently, we have introduced a mechanism to achieve ultrabroadband light funnelling and total transmission through 1D narrow metallic gratings at a specific incidence angle, the so-called plasmonic Brewster angle. This phenomenon is based on impedance matching between the guided modes supported by ultranarrow linear slits and transverse-magnetic waves at oblique incidence. In this paper, we demonstrate that such phenomenon, representing the equivalent of Brewster transmission for plasmonic screens, can also occur in 2D metallic gratings of various structural forms and shapes, and that it may be made insensitive to the azimuthal, or polarization, angle u. This finding may have relevant …


Laser Induced Breakdown Spectroscopy Having Enhanced Signal-To-Noise Ratio, Dennis R. Alexander, Troy Anderson, John C. Bruce Iii Jan 2012

Laser Induced Breakdown Spectroscopy Having Enhanced Signal-To-Noise Ratio, Dennis R. Alexander, Troy Anderson, John C. Bruce Iii

Department of Electrical and Computer Engineering: Faculty Publications

A material can be analyzed using short pulses by applying a first pulse and a second pulse to the material in which the second pulse is delayed relative to the first pulse. The first and second pulses are directed toward a material along collinear paths, and the material is ablated using the first pulse to cause particles to be emitted from the surface of the material. The emitted particles are atomized and/or ionized using the second pulse, and the radiation from the atomized and/or ionized particles is analyzed.


Empirical Correction For Spectroscopic Ellipsometric Measurements Of Rough Or Textured Surfaces, Craig M. Herzinger, Blaine D. Johs, Mathias M. Schubert, Tino Hofmann Jan 2012

Empirical Correction For Spectroscopic Ellipsometric Measurements Of Rough Or Textured Surfaces, Craig M. Herzinger, Blaine D. Johs, Mathias M. Schubert, Tino Hofmann

Department of Electrical and Computer Engineering: Faculty Publications

A method of applying spectroscopic ellipsometry to arrive at accurate values of optical and physical properties for thin films on samples having rough or textured surfaces.


Enhancement Of Optical Emission From Laser-Induced Plasmas By Combined Spatial And Magnetic Confinement, L. B. Guo, W. Hu, B. Y. Zhang, X. N. He, C. M. Li, Y. S. Zhou, Z. X. Cai, X. Y. Zeng, Yongfeng Lu Jul 2011

Enhancement Of Optical Emission From Laser-Induced Plasmas By Combined Spatial And Magnetic Confinement, L. B. Guo, W. Hu, B. Y. Zhang, X. N. He, C. M. Li, Y. S. Zhou, Z. X. Cai, X. Y. Zeng, Yongfeng Lu

Department of Electrical and Computer Engineering: Faculty Publications

Within the past decades, laser-induced breakdown spectroscopy (LIBS) has become a well-established and powerful optical emission spectroscopy (OES) analytical technique [1–5]. As a useful analytical tool, LIBS is used extensively in various areas such as remote detection, hostile environment monitoring, and cultural heritage conservation [6–10]. Researchers are paying more attention to LIBS as a diagnostic method for elemental analysis as it is characterized by fast, real-time, in situ, low invasiveness, and multi-elemental diagnosis, normally without the need for sample preparation [11,12]. However, one of its major drawbacks is its low sensitivity, which seriously hinders further improving the limit of detection …


Apparatus For Dispensing Material, Peter Werner Sutter, Eli Anguelova Sutter Jul 2011

Apparatus For Dispensing Material, Peter Werner Sutter, Eli Anguelova Sutter

Department of Electrical and Computer Engineering: Faculty Publications

An apparatus capable of dispensing drops of material with volumes on the order of Zeptoliters is described. In some embodiments of the inventive pipette the size of the droplets so dispensed is determined by the size of a hole, or channel, through a carbon shell encapsulating a reservoir that contains material to be dispensed. The channel may be formed by irradiation with an electronbeam or other high-energy beam capable of focusing to a spot size less than about 5 nanom eters. In some embodiments, the dispensed droplet remains attached to the pipette by a small thread of material, an atomic …


Generation Of High-Temperature And Low-Density Plasmas For Improved Spectral Resolutions In Laser-Induced Breakdown Spectroscopy, X. N. He, W. Hu, C. M. Li, L. B. Guo, Yongfeng Lu May 2011

Generation Of High-Temperature And Low-Density Plasmas For Improved Spectral Resolutions In Laser-Induced Breakdown Spectroscopy, X. N. He, W. Hu, C. M. Li, L. B. Guo, Yongfeng Lu

Department of Electrical and Computer Engineering: Faculty Publications

Improved spectral resolutions were achieved in laser-induced breakdown spectroscopy (LIBS) through generation of high-temperature and low-density plasmas. A first pulse from a KrF excimer laser was used to produce particles by perpendicularly irradiating targets in air. A second pulse from a 532 nm Nd:YAG laser was introduced parallel to the sample surface to reablate the particles. Optical scattering from the first-pulse plasmas was imaged to elucidate particle formation in the plasmas. Narrower line widths (full width at half maximums: FWHMs) and weaker self-absorption were observed from time-integrated LIBS spectra. Estimation of plasma temperatures and densities indicates that high temperature and …


Nano-Particle/Quantum Dot Based Optical Dode, Dennis R. Alexander, John C. Bruce, Craig A. Zuhlke, Brandon E. Koch, Jitender S. Deogun, Haitham S. Hamza Jan 2011

Nano-Particle/Quantum Dot Based Optical Dode, Dennis R. Alexander, John C. Bruce, Craig A. Zuhlke, Brandon E. Koch, Jitender S. Deogun, Haitham S. Hamza

Department of Electrical and Computer Engineering: Faculty Publications

A particle based optical diode having at least two cavities or at least two regions of a single cavity, wherein the regions contain different types of particles.


Performance Analysis Of Mimo-Sess With Alamouti Scheme Over Rayleigh Fading Channels, Shichuan Ma, Lim Nguyen, Yaoqing Lamar Yang, Won Mee Jang Jan 2011

Performance Analysis Of Mimo-Sess With Alamouti Scheme Over Rayleigh Fading Channels, Shichuan Ma, Lim Nguyen, Yaoqing Lamar Yang, Won Mee Jang

Department of Electrical and Computer Engineering: Faculty Publications

Self-encoded spread spectrum (SESS) is a novel modulation technique that acquires its spreading sequence from the random input data stream rather than through the use of the traditional pseudo-noise code generator. It has been incorporated with multiple-input multiple-output (MIMO) systems as a means to combat fading in wireless channels. In this paper, we present the analytical study of the bit-error rate (BER) performance of MIMO-SESS systems under Rayleigh fading. The BER expressions are derived in closed form, and the veracity of the analysis is confirmed by numerical calculations that demonstrate excellent agreement with simulation results. The performance analysis shows that …


All-Dielectric Invisibility Cloaks Made Of Batio3-Loaded Polyurethane Foam, Di Bao, Khalid Z. Rajab, Yang Hao, Efthymios Kallos, Wenxuan Tang, Christos Argyropoulos, Yongzhe Piao, Shoufeng Yang Jan 2011

All-Dielectric Invisibility Cloaks Made Of Batio3-Loaded Polyurethane Foam, Di Bao, Khalid Z. Rajab, Yang Hao, Efthymios Kallos, Wenxuan Tang, Christos Argyropoulos, Yongzhe Piao, Shoufeng Yang

Department of Electrical and Computer Engineering: Faculty Publications

Transformation optics has led the way in the development of electromagnetic invisibility cloaks from science fiction to engineering practice. Invisibility cloaks have been demonstrated over a wide range of the electromagnetic spectrum, and with a variety of different fabrication techniques. However, all previous schemes have relied on the use of metamaterials consisting of arrays of sub-wavelength inclusions. We report on the first cloaking structure made of a high-k dielectric-loaded foam mixture. A polyurethane foam mixed with different ratios of barium titanate is used to produce the required range of permittivities, and the invisibility cloak is demonstrated to work for all …


Transparent Interconnections Formed By Rapid Single-Step Fabrication Of Graphene Patterns, J. B. Park, W. Xiong, Z. Q. Xie, Y. Gao, M. Qian, M. Mitchell, M. Mahjouri-Samani, Y. S. Zhou, L. Jiang, Yongfeng Lu Jan 2011

Transparent Interconnections Formed By Rapid Single-Step Fabrication Of Graphene Patterns, J. B. Park, W. Xiong, Z. Q. Xie, Y. Gao, M. Qian, M. Mitchell, M. Mahjouri-Samani, Y. S. Zhou, L. Jiang, Yongfeng Lu

Department of Electrical and Computer Engineering: Faculty Publications

We developed a process to form transparent interconnections using graphene patterns that were synthesized by laser chemical vapor deposition. The number of graphene layers was tightly controlled by laser scan speed. Graphene patterns were fabricated at a high scan speed of up to 200 µm/s with a single-step process. The process time is about a million times faster than the conventional chemical vapor deposition method. The fabricated graphene patterns on nickel foils were directly transferred to desired positions on patterned electrodes. The position-controlled transfer with rapid single-step fabrication of graphene patterns provides an innovative pathway for graphene-based interconnections.


Fast Growth Of Graphene Patterns By Laser Direct Writing, J. B. Park, W. Xiong, Y. Gao, M. Qian, Z. Q. Xie, M. Mitchell, Y. S. Zhou, G. H. Han, L. Jiang, Yongfeng Lu Jan 2011

Fast Growth Of Graphene Patterns By Laser Direct Writing, J. B. Park, W. Xiong, Y. Gao, M. Qian, Z. Q. Xie, M. Mitchell, Y. S. Zhou, G. H. Han, L. Jiang, Yongfeng Lu

Department of Electrical and Computer Engineering: Faculty Publications

Rapid single-step fabrication of graphene patterns was developed using laser-induced chemical vapor deposition (LCVD). A laser beam irradiates a thin nickel foil in a CH4 and H2 environment to induce a local temperature rise, thereby allowing the direct writing of graphene patterns in precisely controlled positions at room temperature. Line patterns can be achieved with a single scan without pre- or post-processes. Surprisingly, the growth rate is several thousand times faster than that of general CVD methods. The discovery and development of the LCVD growth process provide a route for the rapid fabrication of graphene patterns for various …


Small Molecule Inhibitors Of Staphylococcus Aureus Rnpa Alter Cellular Mrna Turnover, Exhibit Antimicrobial Activity, And Attenuate Pathogenesis, Patrick D. Olson, Lisa J. Kuechenmeister, Kelsi L. Anderson, Sonja Daily, Karen E. Beenken, Christelle M. Roux, Michelle L. Reniere, Tami L. Lewis, William J, Weiss, Mark Pulse, Phung Nguyen, Jerry W. Simecka, John M. Morrison, Khalid Sayood, Oluwatoyin A. Asojo, Mark S. Smeltzer, Eric P. Skaar, Paul M. Dunman Jan 2011

Small Molecule Inhibitors Of Staphylococcus Aureus Rnpa Alter Cellular Mrna Turnover, Exhibit Antimicrobial Activity, And Attenuate Pathogenesis, Patrick D. Olson, Lisa J. Kuechenmeister, Kelsi L. Anderson, Sonja Daily, Karen E. Beenken, Christelle M. Roux, Michelle L. Reniere, Tami L. Lewis, William J, Weiss, Mark Pulse, Phung Nguyen, Jerry W. Simecka, John M. Morrison, Khalid Sayood, Oluwatoyin A. Asojo, Mark S. Smeltzer, Eric P. Skaar, Paul M. Dunman

Department of Electrical and Computer Engineering: Faculty Publications

Methicillin-resistant Staphylococcus aureus is estimated to cause more U.S. deaths annually than HIV/AIDS. The emergence of hypervirulent and multidrug-resistant strains has further amplified public health concern and accentuated the need for new classes of antibiotics. RNA degradation is a required cellular process that could be exploited for novel antimicrobial drug development. However, such discovery efforts have been hindered because components of the Gram-positive RNA turnover machinery are incompletely defined. In the current study we found that the essential S. aureus protein, RnpA, catalyzes rRNA and mRNA digestion in vitro. Exploiting this activity, high through-put and secondary screening assays identified …


A High-Quality Mach-Zehnder Interferometer Fiber Sensor By Femtosecond Laser One-Step Processing, Longjiang Zhao, Lan Jiang, Sumei Wang, Hai Xiao, Yongfeng Lu, Hai-Lung Tsai Jan 2011

A High-Quality Mach-Zehnder Interferometer Fiber Sensor By Femtosecond Laser One-Step Processing, Longjiang Zhao, Lan Jiang, Sumei Wang, Hai Xiao, Yongfeng Lu, Hai-Lung Tsai

Department of Electrical and Computer Engineering: Faculty Publications

During new fiber sensor development experiments, an easy-to-fabricate simple sensing structure with a trench and partially ablated fiber core is fabricated by using an 800 nm 35 fs 1 kHz laser. It is demonstrated that the structure forms a Mach-Zehnder interferometer (MZI) with the interference between the laser light passing through the air in the trench cavity and that in the remained fiber core. The fringe visibilities are all more than 25 dB. The transmission spectra vary with the femtosecond (fs) laser ablation scanning cycle. The free spectral range (FSR) decreases as the trench length increases. The MZI structure is …


Formation Of Graphene Sheets Through Laser Exfoliation Of Highly Ordered Pyrolytic Graphite, Min Qian, Yun-Shen Zhou, Yang Gao, Jong Bok Park, Tao Feng, Su Mei Huang, Zhuo Sun, Lan Jiang, Yongfeng Lu Jan 2011

Formation Of Graphene Sheets Through Laser Exfoliation Of Highly Ordered Pyrolytic Graphite, Min Qian, Yun-Shen Zhou, Yang Gao, Jong Bok Park, Tao Feng, Su Mei Huang, Zhuo Sun, Lan Jiang, Yongfeng Lu

Department of Electrical and Computer Engineering: Faculty Publications

Freestanding two-dimensional (2D) few-layer graphene was formed through laser exfoliation of highly ordered pyrolytic graphite, using a pulsed neodymium-doped yttrium aluminum garnet (Nd:YAG) laser. Graphene sheets of several nanometers in thickness and micrometers in size were obtained. The laser exfoliation process was investigated at different laser fluences and distances between target and substrate. Three different phases, amorphous carbon, few-layer graphene sheets, and thin graphite films, were obtained as the laser fluence increased. This study reveals an existing route of forming freestanding 2D nanostructures through laser exfoliation.


Terahertz Optical-Hall Effect Characterization Of Two-Dimensional Electron Gas Properties In Algan/Gan High Electron Mobility Transistor Structures, S. Schöche, Junxia Shi, A. Boosalis, P. Kühne, C. M. Herzinger, John A. Woollam, W. J. Schaff, L. F. Eastman, M. Schubert, Tino Hofmann Jan 2011

Terahertz Optical-Hall Effect Characterization Of Two-Dimensional Electron Gas Properties In Algan/Gan High Electron Mobility Transistor Structures, S. Schöche, Junxia Shi, A. Boosalis, P. Kühne, C. M. Herzinger, John A. Woollam, W. J. Schaff, L. F. Eastman, M. Schubert, Tino Hofmann

Department of Electrical and Computer Engineering: Faculty Publications

The free-charge carrier mobility, sheet density, and effective mass of a two-dimensional electron gas are exemplarily determined in the spectral range from 640 GHz to 1 THz in a AlGaN/GaN heterostructure using the optical-Hall effect at room temperature. Complementary midinfrared spectroscopic ellipsometry measurements are performed for analysis of heterostructure constituents layer thickness, phonon mode, and free-charge carrier parameters. The electron effective mass is determined to be (0.22 ± 0.04)m0. The high-frequency sheet density and carrier mobility parameters are in good agreement with results from dc electrical Hall effect measurements, indicative for frequency-independent carrier scattering mechanisms of the …


Reprogrammed Transcriptome In Rhesus-Bovine Interspecies Somatic Cell Nuclear Transfer Embryos, Kai Wang, Hasan H. Otu, Ying Chen, Young Lee, Keith Latham, Jose B. Cibelli Jan 2011

Reprogrammed Transcriptome In Rhesus-Bovine Interspecies Somatic Cell Nuclear Transfer Embryos, Kai Wang, Hasan H. Otu, Ying Chen, Young Lee, Keith Latham, Jose B. Cibelli

Department of Electrical and Computer Engineering: Faculty Publications

Background: Global activation of the embryonic genome (EGA), one of the most critical steps in early mammalian embryo development, is recognized as the time when interspecies somatic cell nuclear transfer (iSCNT) embryos fail to thrive.

Methodology/Principal Findings: In this study, we analyzed the EGA-related transcriptome of rhesus-bovine iSCNT 8- to 16- cell embryos and dissected the reprogramming process in terms of embryonic gene activation, somatic gene silencing, and maternal RNA degradation. Compared with fibroblast donor cells, two thousand and seven genes were activated in iSCNT embryos, one quarter of them reaching expression levels comparable to those found in in vitro …


A Single Chip Computational Sensor System For Neutron Detection Applications, Nathan R. Schemm, Sina Balkir, Michael Hoffman, Mark Bauer, David Schultz, James C. Petrosky, John W. Mcclory, Marcus Natta, Jennifer I. Brand, Jinke Tang, Wendong Wang Jul 2010

A Single Chip Computational Sensor System For Neutron Detection Applications, Nathan R. Schemm, Sina Balkir, Michael Hoffman, Mark Bauer, David Schultz, James C. Petrosky, John W. Mcclory, Marcus Natta, Jennifer I. Brand, Jinke Tang, Wendong Wang

Department of Electrical and Computer Engineering: Faculty Publications

This paper presents the design and test results of a standalone computational radiation sensor system based on a single chip solution. A low-power sensor front end with a charge sensitive amplifier and an event driven analog-to-digital converter is integrated on the same chip as a dedicated microcontroller to process and bin the data from the neutron detector diode heterojunction according to pulse height. This combination effectively implements a single chip multichannel analyzer with the capability to do further processing of the data in software. The design was fabricated in a 0.18 CMOS technology with field tests demonstrating the validity of …


Flying Mobile On-Board Ellipsometer, Polarimeter, Reflectometer And The Like Systems, Blaine D. Johs, Ping He, Martin M. Liphardt, Christopher A. Goeden, John A. Woollam, James D. Welch Jun 2010

Flying Mobile On-Board Ellipsometer, Polarimeter, Reflectometer And The Like Systems, Blaine D. Johs, Ping He, Martin M. Liphardt, Christopher A. Goeden, John A. Woollam, James D. Welch

Department of Electrical and Computer Engineering: Faculty Publications

A substantially self-contained "on-board" material system investigation system for effecting relative translational and rotational motion between a source and detector of electromagnetic radiation and a sample, which system is functionally mounted on a three-dimensional locational system to enable positioning at desired locations on, and distances from, the surface of a sample, including the capability to easily and conveniently effect rotation and/or to change the angle-of-incidence of a beam of electromagnetic radiation onto a sample surface and/or to provide gas flow confined in a mini-chamber near the surface of a sample, at a location at which a beam having UV, VUV, …


Assembly Of Ordered Carbon Shells On Semconducting Nanomaterals, Eli Anguelova Sutter, Peter Werner Sutter May 2010

Assembly Of Ordered Carbon Shells On Semconducting Nanomaterals, Eli Anguelova Sutter, Peter Werner Sutter

Department of Electrical and Computer Engineering: Faculty Publications

In some embodiments of the invention, encapsulated semiconducting nanomaterials are described. In certain embodiments the nanostructures described are semiconducting nanomaterials encapsulated with ordered carbon shells. In some aspects a method for producing encapsulated semiconducting nanomaterials is disclosed. In some embodiments applications of encapsulated semiconducting nanomaterials are described.


Discrete Coordinate Transformation For Designing All-Dielectric Flat Antennas, Wenxuan Tang, Christos Argyropoulos, Efthymios Kallos, Wei Song, Yang Hao Jan 2010

Discrete Coordinate Transformation For Designing All-Dielectric Flat Antennas, Wenxuan Tang, Christos Argyropoulos, Efthymios Kallos, Wei Song, Yang Hao

Department of Electrical and Computer Engineering: Faculty Publications

Transformation electromagnetics provides a practical approach to control electromagnetic fields at will. Based on this principle, novel devices such as the invisible cloak have been proposed. Here we examine the extension of this technique as applied to the design of flat devices in antenna systems. A method using discrete coordinate transformation is proposed, which allows the conversion of conventional devices with curved shapes into flat systems, while preserving their non-dispersive, isotropic, broadband, and lossless properties. Two specific design examples, a flat reflector and a flat lens embedded in free space, are presented. To avoid the loss and narrow bandwidth issues …


Clustering Of Protein Families Into Functional Subtypes Using Relative Complexity Measure With Reduced Amino Acid Alphabets, Aydin Albayrak, Hasan H. Otu, Ugur O. Sezerman Jan 2010

Clustering Of Protein Families Into Functional Subtypes Using Relative Complexity Measure With Reduced Amino Acid Alphabets, Aydin Albayrak, Hasan H. Otu, Ugur O. Sezerman

Department of Electrical and Computer Engineering: Faculty Publications

Background: Phylogenetic analysis can be used to divide a protein family into subfamilies in the absence of experimental information. Most phylogenetic analysis methods utilize multiple alignment of sequences and are based on an evolutionary model. However, multiple alignment is not an automated procedure and requires human intervention to maintain alignment integrity and to produce phylogenies consistent with the functional splits in underlying sequences. To address this problem, we propose to use the alignment-free Relative Complexity Measure (RCM) combined with reduced amino acid alphabets to cluster protein families into functional subtypes purely on sequence criteria. Comparison with an alignment-based approach was …


Bioinformatic Identification And Characterization Of Human Endothelial Cell-Restricted Genes, Manoj Bhasin, Lei Yuan, Derin B. Keskin, Hasan H. Otu, Towia A. Libermann, Peter Oettgen Jan 2010

Bioinformatic Identification And Characterization Of Human Endothelial Cell-Restricted Genes, Manoj Bhasin, Lei Yuan, Derin B. Keskin, Hasan H. Otu, Towia A. Libermann, Peter Oettgen

Department of Electrical and Computer Engineering: Faculty Publications

Background: In this study, we used a systematic bioinformatics analysis approach to elucidate genes that exhibit an endothelial cell (EC) restricted expression pattern, and began to define their regulation, tissue distribution, and potential biological role.

Results:Using a high throughput microarray platform, a primary set of 1,191 transcripts that are enriched in different primary ECs compared to non-ECs was identified (LCB >3, FDR

Conclusion: The study provides an initial catalogue of EC-restricted genes most of which are ubiquitously expressed in different endothelial cells.