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Full-Text Articles in Transport Phenomena

Fluid Pathways For Enhanced Mass Transfer In The Micro Regime: Applications In Novel Pumpless Redox Flow Cell And Zinc Finger Protein-Based Dna Detection, Shaikh Al Mahmud Bhuiyan Jan 2025

Fluid Pathways For Enhanced Mass Transfer In The Micro Regime: Applications In Novel Pumpless Redox Flow Cell And Zinc Finger Protein-Based Dna Detection, Shaikh Al Mahmud Bhuiyan

Theses and Dissertations--Mechanical and Aerospace Engineering

Precise fluid transport through microscale geometries can help optimize electrochemical and biochemical processes by maximizing the mass transfer rate of reactants. By introducing intricate structural features inside microchannels, it is possible to manipulate the fluid motion and direct the flow towards any surface of interest. In this study, we have demonstrated that rationally designed fluid pathways can improve the performance of electrochemical and biochemical systems.

The emergence of additive manufacturing has enabled rapid fabrication of robust structures with intricate features to guide fluid motion. However, their application in nonaqueous electrochemical systems has been limited due to their interaction with organic …


Developing A 3d In Vitro Model By Microfluidics, Hung-Ta Chien Jan 2018

Developing A 3d In Vitro Model By Microfluidics, Hung-Ta Chien

Dissertations and Theses

In vitro tissue models play an important role in providing a platform that mimics the realistic tissue microenvironment for stimulating and characterizing the cellular behavior. In particular, the hydrogel-based 3D in vitro models allow the cells to grow and interact with their surroundings in all directions, thus better mimicking in vivo than their 2D counterparts. The objective of this thesis is to establish a 3D in vitro model that mimics the anatomical and functional complexity of the realistic cancer microenvironment for conveniently studying the transport coupling in porous tissue structures. We pack uniform-sized PEGDA-GelMA microgels in a microfluidic chip to …


Shear Driven Micro-Fluidic Pump For Cardiovascular Applications, Nihad E. Daidzic Apr 2017

Shear Driven Micro-Fluidic Pump For Cardiovascular Applications, Nihad E. Daidzic

Aviation Department Publications

A valveless shear-driven micro-fluidic pump design (SDMFP) for hemodynamic applications is presented in this work. One of the possible medical and biomedical applications is in-vivo hemodynamic (human blood circulation) support/assist. One or more SDMFPs can be inserted/implanted into vascular lumens in a form of a stent/duct in series and/or in parallel (bypass duct) to support blood circulation in-vivo. A comprehensive review of various micro-pump designs up to about mid 2000’s is given in [1,2]. Many of micropump designs considered are not suitable for in-vivo or even in-vitro medical/biomedical applications.

Operating principles, design, and SDMFP features are given in [3]. A …