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Full-Text Articles in Process Control and Systems

A Data-Driven Multivariate Process Monitoring Platform For Knowledge Discovery And Model Building In Industrial Applications, Estelle E. Seghers Mar 2023

A Data-Driven Multivariate Process Monitoring Platform For Knowledge Discovery And Model Building In Industrial Applications, Estelle E. Seghers

LSU Master's Theses

In industrial chemical manufacturing processes, the amount of raw data generated can add complexity in the analysis and understanding of the process dynamics. Being able to properly interpret this data can help improve plant operation, especially regarding safety and profitability. This research has culminated in FastMan-JMP, a platform proposed for monitoring of industrial processes and optimization of the offline data-driven model-building process as part of the process monitoring workflow. FastMan-JMP is a tool developed in Python to apply various data mining and machine learning techniques quickly and easily to better understand valuable patterns and hidden trends in process data. One …


Model-Guided Design Of Rna-Based Synthetic Circuits For The Dynamic Regulation Of Gene Expression, Jordan R. Ryan Apr 2022

Model-Guided Design Of Rna-Based Synthetic Circuits For The Dynamic Regulation Of Gene Expression, Jordan R. Ryan

LSU Master's Theses

A longstanding goal in synthetic biology has been to build synthetic gene circuits with the ability to harness nature’s capability of precise gene expression regulation. Advancements in RNA technology have established RNA-based regulators with distinct advantages over traditional protein-based regulators such as faster signal propagation, versatile programmability, and low cellular burden, which has created an interest in the field to construct innovative synthetic gene circuits using de novo RNA- based regulators. However, our understanding of the behavior and kinetics of RNA-RNA interactions for the construction of gene circuits is incomplete. This thesis proposes a model-guided design framework that integrates mechanistic …