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Full-Text Articles in Process Control and Systems

Neural Network Technologies In The Automatical Control Systems Of Absorption Process For Pureficating Natural Gas, Abdishukurov Maqsudovich Shavkat Mr, Xuecheng Li Li Xuecheng Mr Jul 2026

Neural Network Technologies In The Automatical Control Systems Of Absorption Process For Pureficating Natural Gas, Abdishukurov Maqsudovich Shavkat Mr, Xuecheng Li Li Xuecheng Mr

Technical science and innovation

Analysis of methods and algorithms for synthesizing adaptive control systems for technological processes based on the neural network approach is carried out in this search. The stages of mathematical modeling of complex technological processes using neural network technology were considered. Additionally, an algorithm for solving the interpolation and extrapolation problem that arises in the training process a neural network to control system was proposed. At the final stage of this article, algorithms based on neural network technology are synthesized for the control system for the parameters of the technological process of natural gas purification by absorption


Comprehensive Mechatronic Design Methodology For 6-Dof Stationary Lower Limb Rehabilitation Exoskeleton Robot With Safety-Integrated Control Architecture, Javlonbek Rakhmatillaev Mr., Nodirbek Kimsanboyev Mr., Umidjon Takabaev Mr., Zafar Juraev3 Dr. Dec 2025

Comprehensive Mechatronic Design Methodology For 6-Dof Stationary Lower Limb Rehabilitation Exoskeleton Robot With Safety-Integrated Control Architecture, Javlonbek Rakhmatillaev Mr., Nodirbek Kimsanboyev Mr., Umidjon Takabaev Mr., Zafar Juraev3 Dr.

Chemical Technology, Control and Management

This paper presents the mechatronic design of a proposed six-degree-of-freedom (6-DOF) stationary lower limb rehabilitation exoskeleton (SLLRE) robot, developed through a comprehensive mechatronic design methodology that includes mechanical design, actuator and sensor selection, and the development of a control structure based on a safety-oriented control approach. The proposed 6-DOF SLLRE mechanical design introduces a comprehensive mechanical structure comprising bilateral hip, knee, and ankle joints, degrees of freedom, joint ranges of motion, human parameters for rehabilitation training, as well as the frames and structural elements of the proposed system. Furthermore, the selection of appropriate sensors, actuators, and control architecture for the …


Fuzzy Logic-Based Decision Support System For Adoption Of Industry 4.0 Predictive Maintenance By Manufacturing Industries, Fred E. Peter Jun 2025

Fuzzy Logic-Based Decision Support System For Adoption Of Industry 4.0 Predictive Maintenance By Manufacturing Industries, Fred E. Peter

Tanzania Journal of Engineering and Technology (TJET)

In the context of Industry 4.0, predictive maintenance enhances operational efficiency by optimizing processes, minimizing downtime, and improving cost-effectiveness. However, implementing predictive maintenance requires a systematic approach due to its complexity. This study collected expert input from 15 food and beverage manufacturing industries located in Dar es Salaam, Tanzania, using a purposive sampling technique. Six representatives were selected from each industry, and their opinions were analyzed using MATLAB 7.6 through a fuzzy logic inference system. The analysis focused on key factors influencing Industry 4.0 technology adoption for predictive maintenance, including adoption intention (strategic decision, equipment data, perceived benefit) and perceived …


Wet Gas Metering Performance Using Conventional Flow Measurement Devices, Vitali Mwinyi Jun 2025

Wet Gas Metering Performance Using Conventional Flow Measurement Devices, Vitali Mwinyi

Tanzania Journal of Engineering and Technology (TJET)

The demand for and production of natural wet gas from wells has significantly risen in recent years. Although natural gas liquids hold substantial value in the oil and gas market, their presence in wet gas adversely affects gas metering, leading to overreading during measurement. A comprehensive study has been undertaken to formulate and enhance correlations for rectifying overreading in wet gas metering. Nevertheless, most current correlations are designed for horizontal configurations of traditional meters. Mitigating this constraint is crucial to consider the impact of gravity on pressure loss in vertically oriented systems. This study seeks to evaluate the efficacy of …


Energy Optimal Coverage Motion Trajectory Generation Using A Fourth-Order Motion Profile, Mathias Halinga Jun 2025

Energy Optimal Coverage Motion Trajectory Generation Using A Fourth-Order Motion Profile, Mathias Halinga

Tanzania Journal of Engineering and Technology (TJET)

Industrial machines are widely used in manufacturing sector to manufacture several products to meet customer demands. Most of these industries runs all the time throughout a day leading to high operating cost. To cut costs and satisfy customer demand for precise products, industrial machines’ motion generation is important in improving machine motion precision while using less energy. This study presents a coverage motion energy optimization which is generated by linear interpolation of each segment described by the fourth-order motion profile. The phase changes in the profile are attained with continuity of machine kinematic limits jerk, acceleration, and velocity, which are …


Effects Of Cutting Conditions On Tool Temperature And Material Removal Rate In Turning Operations, Simon I. Marandu Jun 2025

Effects Of Cutting Conditions On Tool Temperature And Material Removal Rate In Turning Operations, Simon I. Marandu

Tanzania Journal of Engineering and Technology (TJET)

Cutting conditions in manufacturing processes have effects on tool temperature and material removal rate. The objective of this study was to investigate the effects of cutting conditions namely spindle speed, feed rate, depth of cut and tool nose radius on tool temperature and material removal rate in turning operations. A total of 81 experiments were conducted to measure tool temperature and material removal rate in order to determine the effects of cutting conditions on tool temperature and material removal rate using ANOVA and regression analysis. The results show that tool nose radius, depth of cut, and spindle speed are significant …


Capacitive Sensors With Ultra-Small Capacitance For Smart Measurement And Control Systems, Rustam Baratov, Farrux Jabbor O'G'Li Ko'charov Aug 2024

Capacitive Sensors With Ultra-Small Capacitance For Smart Measurement And Control Systems, Rustam Baratov, Farrux Jabbor O'G'Li Ko'charov

Chemical Technology, Control and Management

This article discusses methods of low capacitance measurement of capacitive sensors. The results of the study of the amplitude-frequency (AF) and phase-frequency (PF) response of measurement circuits of capacitive sensors for low capacitances measurement, consisting of RC - differentiating elements are presented. The input and output parameters of the differentiating circuit and the complex transfer function are analyzed. The research results show that low capacitances measurement by measuring the rectangular pulses duration is the most effective measurement method.


Cfd Study On Two-Phase Flow Patterns In A Pipe With 90º Elbow In Different Operating Conditions, Hagar Alm-Eldin Bastawissi, Mohammed Ahmed Khafagy, E. A. El Shenawy Prof. Dr., Ahmed M. Salem Dr Mar 2024

Cfd Study On Two-Phase Flow Patterns In A Pipe With 90º Elbow In Different Operating Conditions, Hagar Alm-Eldin Bastawissi, Mohammed Ahmed Khafagy, E. A. El Shenawy Prof. Dr., Ahmed M. Salem Dr

Journal of Engineering Research

Recently, CFD has offered a technological solution for modelling multi-phase flow in which we can make endless simulations with reduced expenses and effort in high accuracy results; we shall also mention that experimental studies have limitations for safety considerations when experimenting with flow in high temperature or pressure values or medium nature as in nuclear or chemical flows.In this paper, we used the ANSYS FLUENT CFD program to simulate the two-phase flow in a pipe to study the effect of attaching a 90-degree elbow fitting to the piping system, seeking to find out the change in the pattern and resulting …


Cost Estimation Proxy Models For Economic Evaluations In Petroleum Projects: A Case Study From The Onshore Gas Field In The Southern Coastal Tanzania Basin, Fulmence Kaborogo Feb 2024

Cost Estimation Proxy Models For Economic Evaluations In Petroleum Projects: A Case Study From The Onshore Gas Field In The Southern Coastal Tanzania Basin, Fulmence Kaborogo

Tanzania Journal of Engineering and Technology (TJET)

Petroleum economic evaluation involves estimating revenues from forecasted production profiles and field costs including capital expenditures (CAPEX), drilling expenses (DRILLEX), and operating expenses (OPEX). The existing cost-estimating tool requires several inputs making it time-intensive and difficult to use with few data during the early stages of projects. Majority of the previously developed time saving cost estimations proxy models rely on unrealistic assumptions that include uniform operational costs for different fields with a different number of wells, casings, and drilled depths. This work focused at developing proxy models that consider the variability of the development costs with different parameters. The developed …


Schaeffler Icvd Coating Machine, Louis Mcgrath Jan 2024

Schaeffler Icvd Coating Machine, Louis Mcgrath

Williams Honors College, Honors Research Projects

Chemical Vapor Deposition (CVD) is mutual technology used to deposit thin film through a gaseous phase by vaporizing the solid materials. This conventional process usually requires high thermal stability of the materials, which is not applicable for most of the polymeric materials. Therefore, a novel process, initiated Chemical Vapor Deposition (iCVD) is developed by introducing the gaseous monument and initiator to form the thin film in-situ. By adjusting the free-radical polymerization in the vapor phase, a variety of thin and uniform polymer films can be achieved. Depending on the chemistry, iCVD has many categories. This report explains the design …


Reducing Food Scarcity: The Benefits Of Urban Farming, S.A. Claudell, Emilio Mejia Dec 2023

Reducing Food Scarcity: The Benefits Of Urban Farming, S.A. Claudell, Emilio Mejia

Journal of Nonprofit Innovation

Urban farming can enhance the lives of communities and help reduce food scarcity. This paper presents a conceptual prototype of an efficient urban farming community that can be scaled for a single apartment building or an entire community across all global geoeconomics regions, including densely populated cities and rural, developing towns and communities. When deployed in coordination with smart crop choices, local farm support, and efficient transportation then the result isn’t just sustainability, but also increasing fresh produce accessibility, optimizing nutritional value, eliminating the use of ‘forever chemicals’, reducing transportation costs, and fostering global environmental benefits.

Imagine Doris, who is …


Employment Of Intelligent Predictive Maintenance On Thermal Power Plant Component Parts Taking Condenser Vacuum As A Case Study, Titus Ajewole Nov 2023

Employment Of Intelligent Predictive Maintenance On Thermal Power Plant Component Parts Taking Condenser Vacuum As A Case Study, Titus Ajewole

Tanzania Journal of Engineering and Technology (TJET)

This work proposes deployment of machine learning in the maintenance of individual constituent parts of steam power plant assemblages. With the condenser vacuum of a steam turbine (in a six-turbine plant assemblage) taken as a case study, information on the past operating parameters of the selected plant component was used to forecast its future working condition. Based on Exponential Gaussian Process of Regression, a model was developed, trained using the diachronic operational data, and employed in determining the future. A quantitative evaluation was employed to provide the distribution of the test values of the data about the lines of regression, …


Dependence Of The Granulometric Composition Of Chalk During Granulation In A Turbulized Layer, N.A. Annaev, S.Kh. Nurmukhamedov, Zh.V. Sultonov, N.Sh. Khudoiberdieva Oct 2023

Dependence Of The Granulometric Composition Of Chalk During Granulation In A Turbulized Layer, N.A. Annaev, S.Kh. Nurmukhamedov, Zh.V. Sultonov, N.Sh. Khudoiberdieva

Chemical Technology, Control and Management

The article presents the results of an experimental study on chalk granulation in the turbulized layer of a turboblade granulator. The design of the apparatus combines the following sequential processes: grinding, granulating and compacting newly formed granules. In addition, this device has the ability to carry out both rotational and reciprocating motion. It has been established that preliminary grinding of the feedstock increases the efficiency of the granulation process and improves the quality of the finished product. In the experiments, four substances were used to create 2 astringent suspensions and the optimal combination and their ratios were determined. The experiments …


Designing A Cylindrical Capacitive Based Sensor For Monitoring The Table Salt’S Moisture Content During Iodization, Mwajuma Lungo Sep 2023

Designing A Cylindrical Capacitive Based Sensor For Monitoring The Table Salt’S Moisture Content During Iodization, Mwajuma Lungo

Tanzania Journal of Engineering and Technology (TJET)

Coaxial cylinder capacitive moisture sensor for determination of moisture content of table salts has been fabricated. The CMS method for determination of moisture content of table salts overcomes the effect of evaporation of iodine in table salt which results from heating in the oven drying method. The CMS overcomes the polarization effect result from the resistive methods of moisture content determination and it is non expensive to construct and it has high accuracy since measurements involves programming system in interpretation of the results. In this research, moisture content sensor based on capacitive principal created using two coaxial cylinders with height …


Review On Modifications Of Sisal Fibers For Textile Applications, Liberato V Haule Jun 2023

Review On Modifications Of Sisal Fibers For Textile Applications, Liberato V Haule

Tanzania Journal of Engineering and Technology (TJET)

Properties of sisal fibers such as high coarseness and poor drapability made the fibers less suitable in production of conventional textiles compared to synthetic fibers. The environmental consciousness and depletion of petrochemical resources have attracted researchers on investigating the use of natural fibers in the industrial production of conventional textiles. Sisal is among highly researched natural fibers due to its features such as strength, recyclability, availability, low processing cost, light weight and ease process ability. This paper reviews possible modifications of sisal fibers to enhance performance in conventional textiles applications


Factors Influencing Total Productive Maintenance Implementation For Thermal Generation Plants, Ismail W. R. Taifa Dr Feb 2023

Factors Influencing Total Productive Maintenance Implementation For Thermal Generation Plants, Ismail W. R. Taifa Dr

Tanzania Journal of Engineering and Technology (TJET)

This study accepts that the technical and administrative factors can amplify effective total productive maintenance (TPM) implementation at thermal generation plants. It is noted that there is a limited number of studies that have attempted to understand the subject of TPM implementation in the energy sector. Noting this shortcoming, the authors thought it crucial to generate empirical evidence on the factors influencing effective TPM implementation for thermal generation plants, with evidence from gas-fired plants. A sample of 88 respondents was selected and consulted. Data were collected through questionnaires and analyzed quantitatively by inferential statistics and qualitatively through thematic analysis using …


Developing Algorithms For Automating The Processes Of Forming The Optimal Structural Composition Of Production - Technological Modules, Alisher Mamajanov, Sarvar Botir Ugli Nabiyev Jun 2021

Developing Algorithms For Automating The Processes Of Forming The Optimal Structural Composition Of Production - Technological Modules, Alisher Mamajanov, Sarvar Botir Ugli Nabiyev

Chemical Technology, Control and Management

In this research, we developed appropriate algorithms for the formation of the optimal structural composition of production - technological modules (PTM) based on the automation of the processes of determining and ensuring the functional-parametric compatibility (FPC) of their components. These algorithms are based on the developed mathematical models on the basis of the use of analytical methods for implementing the interconnection between the main components of the PTM.


Problem Solving Methods For Synthesis Of Physical Principles Of Mechatronic Module Operations In Intelligent Robotic Systems, Nazarov Khayriddin Nuritdinovich Jun 2021

Problem Solving Methods For Synthesis Of Physical Principles Of Mechatronic Module Operations In Intelligent Robotic Systems, Nazarov Khayriddin Nuritdinovich

Chemical Technology, Control and Management

The scientific paper investigates the methods for solving problems of synthesis of physical principles of operation of mechatronic modules of intelligent robotic systems are considered.

In addition, it deals with the specifics of the process of synthesis of the physical principles of the operation of mechatronic modules using predicate models, list models and information matrices of physical and technical effects.

It shows the interpretation of the components of the model of the system for the synthesis of the physical principles of operation of mechatronic modules of intelligent robotic systems and automatic control and the features of the synthesis algorithm for …


Economic Feasibility Of Mixed Plastic Waste Pyrolysis Using Twin Reactor System In Northwest Arkansas, Carol Rogers, Patricia Means, Renato Gonzalez, Kaida Sheets, Hayden Townsend May 2021

Economic Feasibility Of Mixed Plastic Waste Pyrolysis Using Twin Reactor System In Northwest Arkansas, Carol Rogers, Patricia Means, Renato Gonzalez, Kaida Sheets, Hayden Townsend

Chemical Engineering Undergraduate Honors Theses

Plastic waste generation is increasing at an unsustainable rate while recycling solutions remain stagnant. As a chemical means of recycling, mixed plastic waste pyrolysis can generate synthetic oil appropriate for use as fuel in power generation from plastic waste that otherwise accumulates in landfills. With the scaling of a commercial plastic pyrolysis process in Northwest Arkansas (NWA) modeled after an operational sawdust pyrolysis unit in Huntsville, Arkansas, economic analysis resulted in 26.3% internal rate of return. Therefore, construction of a commercial mixed plastic-to-fuel pyrolysis plant is economically justified and should be pursued. To effectively implement the proposed design, NWA must …


Economic Feasibility Of A Methanol To Dimethyl Ether Production Process To Avoid Contract Failure Shortfalls From The Covid-19 Pandemic, Jacob Noll, Robert Wasson, Harrison Mckinnis May 2021

Economic Feasibility Of A Methanol To Dimethyl Ether Production Process To Avoid Contract Failure Shortfalls From The Covid-19 Pandemic, Jacob Noll, Robert Wasson, Harrison Mckinnis

Honors Theses

Our team entered the 2021 AVEVA Academic Competition, where teams of undergraduate senior chemical engineering students competed across the country. The competition was composed of two parts: the base case design and the optimization of a chemical process. As part of the competition, our team is acting as the Engineering team for a fictional company that has given us this project. Due to COVID-19, our methanol producing company has lost a contract with a customer, leaving 23,000 tonnes/yr of unclaimed methanol. We have two choices with this methanol: either sell the methanol on the market at the spot price for …


Data-Driven Tools Guided By First-Principles For Scale Modeling, Sadegh Poozesh Jan 2021

Data-Driven Tools Guided By First-Principles For Scale Modeling, Sadegh Poozesh

Progress in Scale Modeling, an International Journal

For decades, traditional scale-modeling techniques have been relying on first-principles models (FPMs). FPMs have been used to find non-dimensional numbers (PIs) and identify normalized underlying forces and energies behind the phenomenon in focus. The two main challenges with FPM-based PIs extraction are finding the relevant PIs and proper correlations between PIs. The emergence and surge of data-driven modeling (DDM) provide a new opportunity to leverage experimental data in model development across scales/plants. In this paper, first, the two mentioned issues in PIs development will be elaborated to reveal the gap, and second, a new insight into scale modeling and similarity …


A Geometric Description Of The Set Of Stabilizing Pid Controllers, Keqin Gu, Qian Ma, Huiqing Zhou, Mahzoon Salma, Xingzi Yang Jan 2021

A Geometric Description Of The Set Of Stabilizing Pid Controllers, Keqin Gu, Qian Ma, Huiqing Zhou, Mahzoon Salma, Xingzi Yang

SIUE Faculty Research, Scholarship, and Creative Activity

This article developed a new method to described the set of stabilizing PID control. The method is based on D-parameterization with natural description of the set. It was found that the stability crossing surface is a ruled surface that is completely determined by a curve known as discriminant. The discriminant is divided into sectors at the cusps. Corresponding to the sectors, the stability crossing surface is divided into positive and negative patches. A systematic study is conducted to identify the regions with a fixed number of right half-plane characteristic roots. The crossing directions of characteristic roots for positive patches and …


Fermentability Of Concentrated Sulfuric Acid Hydrolyzates From Aspenwood And Pinewood, Kando Janga Dec 2020

Fermentability Of Concentrated Sulfuric Acid Hydrolyzates From Aspenwood And Pinewood, Kando Janga

Tanzania Journal of Engineering and Technology (TJET)

The fermentability of hydrolyzates derived from two-stage concentrated sulfuric acid hydrolysis of Trembling aspen (Populus tremula) and Scots pine (Pinus sylvestris) were investigated. Three types of hydrolyzates were produced at mild, moderate and high decrystallization severity conditions. Portions of each of the original hydrolyzates were concentrated by vacuum evaporation to increase the sugar fraction to simulate industrial applications. Both sets of hydrolyzates were fermented anaerobically using Saccharomyces cerevisiae ATCC 96581. After 23 hours of fermentation, complete glucose consumption was observed for all the original hydrolyzates, with no signs of inhibition. The ethanol yields from these hydrolyzates ranged from 68% to …


Thermal Control Development Of A Proton Exchange Membrane Fuel Cell System, Ola Mohammed Taha Al-Shalash Aug 2020

Thermal Control Development Of A Proton Exchange Membrane Fuel Cell System, Ola Mohammed Taha Al-Shalash

Mechanical Engineering Theses

A fuel cell is an electrochemical energy conversion device that uses fuel to generate electricity. It basically converts the chemical energy of reactants directly into electricity without combustion. In a Proton Exchange Membrane Fuel Cell (PEMFC), the reactants, hydrogen and oxygen, are fed into the two electrodes, anode and cathode, respectively. A reaction takes place at each electrode and produces electricity, as well as water, and heat as the by-products. In order to maximize performance of a fuel cell, many factors can be considered for tuning and control. Temperature management is one of these factors.

A thermal-fluid model of a …


Cfd Modelling Of Multiphase Flow In Static Mixer, Silverrajan Viknesvaran Aug 2020

Cfd Modelling Of Multiphase Flow In Static Mixer, Silverrajan Viknesvaran

Student Works (2020-2029)

Modelling of Multiphase flow through a Kenics static mixer were presented in this paper. Multiphase mixing is a challenging process in industries such as pharmaceutical, food and petroleum since two-different phases can be immiscible towards each other. Stirred tank mixing is the most common method used in industries. However, this type of method costs a lot in terms of energy and manpower specially when mixing immiscible liquids. Hence, The Kenics Static Mixer could be a good solution for multiphase mixing when its correctly configured and studied. Two phases used in this paper were aqueous solution: refined CMC as continuous phase …


Thermodynamic Analysis And Optimization Of Organic Rankine Cycles Using 1-Butylpyridinium Tetrafluoroborate As A Geothermal Fluid, Kazemi Shabnam Aug 2020

Thermodynamic Analysis And Optimization Of Organic Rankine Cycles Using 1-Butylpyridinium Tetrafluoroborate As A Geothermal Fluid, Kazemi Shabnam

Student Works (2020-2029)

Organic Rankine cycle (ORC) is a promising technology for electricity generation by utilizing heat sources at low to moderate temperature that ranges between 80-350° C. In the present work, an ionic liquid (1-butylpyridinium tetrafluoroborate, C9H14NBF4), a known green chemical and non-volatile compound with good thermal and chemical stability, significant heat capacity, low vapor pressure and a wide liquid temperature range (25 to 459 °C), is utilized as a geothermal fluid. Simulation and optimization were conducted for a basic organic Rankine cycle (basic ORC), a regenerative organic Rankine cycle (RORC) and a two-stage evaporative organic Rankine cycle (TSORC) by maximizing exergy …


Effects Of New And Recycle Flux On The Mechanical Properties Of Submerged Arc Welded (Saw) Line Pipe Grade X52m And X65m, Taib Meor Mohd Adli Jun 2020

Effects Of New And Recycle Flux On The Mechanical Properties Of Submerged Arc Welded (Saw) Line Pipe Grade X52m And X65m, Taib Meor Mohd Adli

Student Works (2020-2029)

Two line pipe grade X52M and X65M were manufactured using submerged arc welding process. For each grade, two different welding flux condition were simulated, i.e. 100% new flux and 100% recycle flux. The flux used was aluminate basic type trade name OP 132. The outside diameter and wall thickness for X52M was 610mm x 12.7mm and for X65M was 762mm x 14.3mm. Lower weld re-entrant angle and higher weld bead height were observed in recycle flux condition. Lower weld manganese content recorded in recycle flux condition. And lower mechanical tests (i.e. tensile, impact, and hardness) value reported for recycle flux …


The Potentials Of Faecal Sludge Treatment Using Local Conditioners In Tanzania: A Review, Doglas Benjamin1 Dec 2019

The Potentials Of Faecal Sludge Treatment Using Local Conditioners In Tanzania: A Review, Doglas Benjamin1

Tanzania Journal of Engineering and Technology (TJET)

Worldwide, every day human beings generate millions of tons of Faecal Sludge (FS), which is rich in water, nutrients, energy, and organic compounds. Yet FS is not being managed in a way that permits us to derive value from its reuse, while at the same time, millions of farmers struggle with depleted soils and lack of water. In most of the developing countries, energy for cooking is mainly derived from cutting of trees, either as wood or charcoal. Resource recovery and reuse from FS can create livelihoods, enhance food security, support green economies, reduce waste and contribute to cost recovery …


Stability Analysis Of A More General Class Of Systems With Delay-Dependent Coefficients, Chi Jin, Keqin Gu, Islam Boussaada, Silviu-Iulian Niculescu May 2019

Stability Analysis Of A More General Class Of Systems With Delay-Dependent Coefficients, Chi Jin, Keqin Gu, Islam Boussaada, Silviu-Iulian Niculescu

SIUE Faculty Research, Scholarship, and Creative Activity

This paper presents a systematic method to analyse the stability of systems with single delay in which the coefficient polynomials of the characteristic equation depend on the delay. Such systems often arise in, for example, life science and engineering systems. A method to analyze such systems was presented by Beretta and Kuang in a 2002 paper, but with some very restrictive assumptions. This work extends their results to the general case with the exception of some degenerate cases. It is found that a much richer behavior is possible when the restrictive assumptions are removed. The interval of interest for the …


Fluid Agitation Studies For Drug Product Containers Using Computational Fluid Dynamics, Matthew Hiroki Ichinose Dec 2018

Fluid Agitation Studies For Drug Product Containers Using Computational Fluid Dynamics, Matthew Hiroki Ichinose

Master's Theses

At Amgen, the Automated Vision Inspection (AVI) systems capture the movement of unwanted particles in Amgen's drug product containers. For quality inspection, the AVI system must detect these undesired particles using a high speed spin-stop agitation process. To better understand the fluid movements to swirl the particles away from the walls, Computational Fluid Dynamics (CFD) is used to analyze the nature of the two phase flow of air and a liquid solution.

Several 2-D and 3-D models were developed using Fluent to create simulations of Amgen's drug product containers for a 1 mL syringe, 2.25 mL syringe, and a 5 …