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Full-Text Articles in Biochemical and Biomolecular Engineering
Crossflow Microfiltration Of Recombinant Escherichia Coli Lysates After High Pressure Homogenization, Stuart M. Bailey, Michael M. Meagher
Crossflow Microfiltration Of Recombinant Escherichia Coli Lysates After High Pressure Homogenization, Stuart M. Bailey, Michael M. Meagher
Papers in Biotechnology
Abstract: Crossflow membrane filtration was used to process recombinant Escherichia coli cell lysates containing protein inclusion bodies after high pressure homogenization. The number of passes through the high pressure homogenizer changed the viscosities and average particle sizes of the cell lysates. The different cell lysates were processed with a hollow fiber unit containing microfiltration membranes and a plate and frame unit with either ultrafiltration or microfiltration membranes. There were differences in permeate flux and protein transmission for the various membranes with the best performing membranes giving permeate fluxes greater than 60 L m−2 h−1 and protein transmissions greater than 90%. …
Tomographic And Particle Tracking Studies In A Liquid-Solid Riser, Shantanu Roy, Jinwen Chen, Sailesh B. Kumar, M. (Muthanna) H. Al-Dahhan, M. P. Duduković
Tomographic And Particle Tracking Studies In A Liquid-Solid Riser, Shantanu Roy, Jinwen Chen, Sailesh B. Kumar, M. (Muthanna) H. Al-Dahhan, M. P. Duduković
Chemical and Biochemical Engineering Faculty Research & Creative Works
A Liquid-Solid Circulating Fluidized Bed is a Potential Reactor of Interest in a Variety of Industrial Processes, Such as Petroleum Refining, and in the Synthesis of Fine Chemicals, Petrochemicals, and Foodstuffs. Rapid Deactivation of the Solid Catalyst in These Processes Necessitates Regeneration and Regulation of the Solids into the Riser Section in Which the Principal Reaction is Accomplished. in This Study We Show that Computer-Automated Radioactive Particle Tracking (CARPT) Can Be Used to Obtain Solids Velocity Patterns in the Riser and that Backflow of Solids Exists at the Tested Liquid Velocities. Γ-Ray Computed Tomography (CT) Reveals Slightly Higher Solids Concentrations …
Assessment Of The Effects Of High-Pressure Operation On The Liquid-Solid Mass-Transfer Coefficient In Trickle-Bed Reactors, M. (Muthanna) H. Al-Dahhan, W. Highfill, M. Friedman
Assessment Of The Effects Of High-Pressure Operation On The Liquid-Solid Mass-Transfer Coefficient In Trickle-Bed Reactors, M. (Muthanna) H. Al-Dahhan, W. Highfill, M. Friedman
Chemical and Biochemical Engineering Faculty Research & Creative Works
Trickle-Bed Reactors Are Used Widely in Industry and Are Usually Operated at High Pressure. All the Studies on Liquid-Solid Mass Transfer in Such Reactors Were Performed under Atmospheric Pressure And, Hence, the Empirical Correlations for Liquid-Solid Mass-Transfer Coefficients (K1s and K1sa) Were Developed based on Atmospheric Data. However, These Correlations Incorporate One or More of the Parameters Affected by Pressure (E.g., Liquid Holdup, Catalyst Wetting Efficiency, Pressure Drop, Gas Density). in This Work the Effects of High Pressure and High Gas Flow Rates on the Predicted Coefficients using Some of These Correlations Are Evaluated. It is Shown that There Are …
Limitations And Dynamics Imposed On Multicomponent Batch Distillation By Tray Hydraulics, Keith G. Tomazi
Limitations And Dynamics Imposed On Multicomponent Batch Distillation By Tray Hydraulics, Keith G. Tomazi
Chemical and Biochemical Engineering Faculty Research & Creative Works
Batch distillation models incorporating a complete set of hydraulic relations, energy balances, and tray efficiencies and simpler models based upon constant molar holdup and zero holdup (the Rayleigh equation) were used to obtain distillation curves and optimal reflux policies. The approach to hydraulic limitations was monitored in the complete hydraulic model. The results indicate that during a multicomponent batch distillation the combination of the changes in the liquid composition and liquid flow rates causes the molar holdup on the trays to vary with time and, consequently, the characteristic time constant of the trays changes. The predicted composition profiles for descriptions …
High-Pressure Trickle-Bed Reactors: A Review, Muthanna H. Al-Dahhan, Faical Larachi, Milorad P. Dudukovic, Andre Laurent
High-Pressure Trickle-Bed Reactors: A Review, Muthanna H. Al-Dahhan, Faical Larachi, Milorad P. Dudukovic, Andre Laurent
Chemical and Biochemical Engineering Faculty Research & Creative Works
A Concise Review of Relevant Experimental Observations and Modeling of High-Pressure Trickle-Bed Reactors, based on Recent Studies, is Presented. the Following Topics Are Considered: Flow Regime Transitions, Pressure Drop, Liquid Holdup, Gas-Liquid Interfacial Area and Mass-Transfer Coefficient, Catalyst Wetting Efficiency, Catalyst Dilution with Inert Fines, and Evaluation of Trickle-Bed Models for Liquid-Limited and Gas-Limited Reactions. the Effects of High-Pressure Operation, Which is of Industrial Relevance, on the Physicochemical and Fluid Dynamic Parameters Are Discussed. Empirical and Theoretical Models Developed to Account for the Effect of High Pressure on the Various Parameters and Phenomena Pertinent to the Topics Discussed Are Briefly …