Chemical Engineering Commons^™

L-Ergothioneine Slows The Progression Of Age-Related Hearing Loss In Cba/Caj Mice, Mark A. Bauer, Parveen Bazard, Alejandro A. Acosta, Nidhi Bangalore, Lina Elessaway, Mark Thivierge, Moksheta Chellani, Xiaoxia Zhu, Bo Ding, Joseph P. Walton, Robert D. Frisina

Chemical and Biochemical Engineering Faculty Research & Creative Works

The naturally occurring amino acid, l-ergothioneine (EGT), has immense potential as a therapeutic, having shown promise in the treatment of other disease models, including neurological disorders. EGT is naturally uptake into cells via its specific receptor, OCTN1, to be utilized by cells as an antioxidant and anti-inflammatory. In our current study, EGT was administered over a period of 6 months to 25–26-month-old CBA/CaJ mice as a possible treatment for age-related hearing loss (ARHL), since presbycusis has been linked to higher levels of cochlear oxidative stress, apoptosis, and chronic inflammation. Results from the current study indicate that EGT can prevent aging …

Sulfonated Ionomer Composite Membranes For Use In Vanadium Redox Flow Batteries, Xueting Wang

All Dissertations

While vanadium redox flow batteries (VRFBs) have garnered significant attention as a promising scalable energy storage technology, the current membrane material used in this technology, Nafion™, suffers from high cross mixing of vanadium ions in the liquid electrolytes, directly impacting battery performance properties such as the voltage and coulombic efficiencies, as well as resulting in a reduction in the overall battery lifetime. The use of ionomer nancomposites has proven to be one promising route of directly addressing the issue of high ion crossover, though the mechanism by which the nanoparticles act to reduce crossover remains in open question. Herein, the …

Modeling Sex-Specific Changes In Myocardial Fibrosis, Grace Martin

Chemical Engineering Undergraduate Honors Theses

Heart disease the leading cause of death for both men and women in the United States. Cardiac fibrosis, or accumulation of extracellular matrix proteins in the heart, can occur after a heart attack and increase the risk for further complications. Current treatments for heart disease do not include extracellular matrix regulators, partly due to the complicated signaling network responsible for the production of these proteins. By using a computational model of the signaling network in cardia fibroblasts, the relationship between particular molecules and downstream extracellular matrix production can be examined.

Biological sex is an important factor for cardiac health and …

Electrode Engineering For Enhanced Performance And Low-Cost Redox Flow Batteries, Abena Williams

All Dissertations

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Developing Anisotropic Soft Matter As Functional Materials To Interface With Biological Systems, Homa Ghaiedi

Graduate Theses and Dissertations

Liquid crystals (LCs) constitute a subset of soft matter possessing hybrid characteristics from both liquid and crystalline phases. In this state, the center of masses remains uncorrelated similar to an isotropic phase, while the long axis of molecules aligns in parallel, resulting in molecules exhibiting orientational and positional order, either individually or concurrently. The directional alignment inherent in LCs arises from the asymmetrical shape and structure of the constituent molecules, causing a spontaneous self-assembly into ordered phases. This cooperative molecular behavior manifests distinctive optical features when subjected to cross polarizers. The remarkable sensitivity of LCs to external stimuli, including temperature, …

Yeast Surface Display Of Multiple Heterologous Proteins Via Molecular And Biochemical Processing Techniques, Shadrach Ibinola

Graduate Theses and Dissertations

The arming of yeast cell wall, also known as yeast surface display, is an effective technology for expressing target proteins extracellularly. It has been shown to provide bioengineered yeast with qualities that are not known to native yeast such as the ability to survive harsh conditions including high pH and temperature, for example. Furthermore, this technique has been implemented for various applications which include, protein engineering, bioethanol production, bioremediation, vaccine construction, and antibody development. The major mechanisms of yeast surface display exploit agglutination, flocculation, or proteins with internal repeats as the means by which a target (protein) is covalently attached …

A Computational Investigation Into Thermo-Kinetic Parameters Governing The Decomposition Of Bio-Oil Model Compounds, Ali Huseein Aljefri

Theses

Among notable products from thermal degradation of biomass are simple oxygen-containing aromatics. These compounds typically appear in high loads in collected bio-oil derived from biomass. As such, it is important to comprehend the decomposition chemistry of this category of compounds. This thesis takes on board a general approach to report thermo-kinetic parameters that govern decomposition of a selected set of bio-oil model compounds in two distinct systems: firstly radical-derived pathways in the gas phase and secondly thermal degradation in their condensed media. The first is attained through accurate density functional calculations while the second is accomplished through the use of …

Valorization Of Date Palm Waste For The Isolation, Characterization, And Surface Chemistry Modification Of Nanocellulose, Mohsin Raza

Dissertations

This dissertation focuses on the utilization of date palm waste, a lignocellulosic material, as a source for the extraction of nanocellulose (NC), a versatile biopolymer with applications in biodegradable composites, bioplastics, and food packaging. Conventional methods of NC production using mineral acids such as sulphuric and hydrochloric acid are reaching their limits of toxicity, so more environmentally friendly alternatives such as ionic liquids (ILs) are being explored. The research focuses on the characterization of different date palm wastes to evaluate their α−cellulose content, lignocellulosic character, and thermal stability. By comparing extraction methods with mineral acids and ILs, the study evaluates …

Smart Manufacturing Of Cement: From Lab-Scale Simulation And Testing To Industry-Scale Deployment., Juan David Tabares Tamayo

Electronic Theses and Dissertations

Cement kilns are controlled by experienced process operators who follow experience-based industry guidelines using data collected and fundamental knowledge. The manufacturing process, which is equipped with sensors and equipment, transfers data/information to the operators to aid standardized decision-making operations. In contrast, companies have used such data to develop and implement digital solutions for predictive control systems; in effect, FLSmidth and Rockwell Automation. However, despite the availability of automated control systems and investigation in automation for process monitoring and optimization, opportunities to radically optimize cement manufacturing are still abundant and in need of implementation. Therefore, this research developed simulation models and …

Mechanical Property Simulations Of Ploybenzimidazole Membranes., Blake Alexander Clark

Electronic Theses and Dissertations

This work explores mechanical properties of membranes made of polybenzimidazole utilizing molecular simulations. These simulations researchers to narrow down polybenzimidazole membrane compositions to viable candidates. These simulations are quicker than current purely experimental methods. The increase in throughput would be achieved by eliminating compositions that have unfavorable mechanical properties through preliminary simulation work before moving onto experimental methods. Determining polybenzimidazole membranes’ mechanical properties experimentally would, therefore, allow for researchers to speed up research in areas such as fuel cells and electrolyzers that make use of polybenzimidazole membranes. This study uses Materials Studio and the COMPASS III forcefield to perform these …

Improving Static Cold Storage Life Of The Human Heart Before Transplant, Juan Sebastian Rodriguez Paez

Theses and Dissertations

Organ storage and transportation are critical steps for the success of organ transplantation. Static cold storage (SCS) of hearts for heart transplantation (HTx) remains the standard approach. However, SCS may involve damage to the tissue resulting from extended hypothermic preservation, potentially affecting organ viability. More over, the temperature distribution on and within the heart is unknown during heart transplantation. Therefore, there is an interest to study different stages of the heart transplantation process towards determining the 3D temperature distribution on and within the heart. There could be a possibility of having a hypothermic injury in different parts of the heart …

Synthesis Of Durable Zeolite 13x Insertion Coatings And Scaled-Up Experimental Demonstration For Co2 Capture, Daniel Jamil Hocheimy

Theses and Dissertations

Minimizing the energy requirement for capturing carbon dioxide (CO₂) from post-combustion sources is critical to efficient industrial decarbonization and subsequent mitigation of the effects of climate change. The current portfolio of CO₂ capture technologies includes absorption, membrane separation and packed bed adsorption, which suffer from high energy and temperature requirements, scalability, and location dependency issues. Adsorption-based systems could cater to these concerns; however, their current embodiments primarily use packed adsorbent bed design and electricity-driven vacuum pumps to regenerate them. While simple and easy to fabricate, these designs are not scalable and cannot use heat to regenerate them …

Enzymatic Production Of Cyclodextrin Using Cyclodextrin Glycosyltransferase Immobilized In Metal Organic Frameworks (Mofs), Babatunde Azeez Ogunbadejo

Thesis/ Dissertation Defenses

Cyclodextrins (CDs) and their derivatives have attracted significant attention in the pharmaceutical, food, and textile industries, which has led to an increased demand for their production. CDs are typically produced by the action of cyclodextrin glycosyltransferase (CGTase) on starch. Owing to the relatively high cost of enzymes, the economic feasibility of the entire process strongly depends on the effective retention and recycling of CGTase in the reaction system, while maintaining the enzyme’s activity and stability. Previous supports used for this purpose have numerous drawbacks, including enzyme leaching, activity loss and significant mass transfer limitations. The aim of this dissertation was …

Thermogravimetric Analysis And Chemical Kinetics Of Waste Tires, Mahir Mohammed Said

Tanzania Journal of Engineering and Technology (TJET)

The focus of this paper is to analyse the pyrolysis reaction of waste tires. The pyrolysis was studied experimentally using thermal and chemical kinetics. The tires were pyrolyzed using thermogravimetry at a temperature range of 200 to 600°C, with heating rates of 10, 20, and 50°C/min. The activating energy was observed to increase with increased temperature. The highest activating energy was 101.02 kJ/mol at a heating rate of 50°C/min.

Enhanced Post Deposition Annealing Conditions On The Fabrication Of High Quality Thermochromic Vanadium Dioxide Films, Nuru R. Mlyuka

Tanzania Journal of Engineering and Technology (TJET)

Sputter deposition of thermochromic VO2 thin films for smart window applications has been faced with several challenges including the need for high deposition temperature, extremely precise and narrow range of oxygen/argon flow ratio and target poisoning during sputtering. Deposition of VO2 at room temperature without oxygen followed by post-deposition annealing has been cited as one of the potential mitigations to the challenge. In this study, the effects of post-deposition annealing conditions on the structural, electrical and optical properties of VO2 thin films are reported. The films were prepared on soda lime glass substrates using DC magnetron sputtering of metallic vanadium …

Design And Optimization Of An Azeotropic Distillation Pilot Plant For The Production Of Pure Ethanol, Samwel V. Manyele

Tanzania Journal of Engineering and Technology (TJET)

This study aimed to design an azeotropic distillation plant using Aspen Plus® V10 software and determine optimal process conditions for producing pure ethanol greater than 95% from pre-concentrated near-azeotropic ethanol-water solution. The non-random two-liquid Redlich-Kwong thermodynamic model was the base method for property analysis and performance prediction. Modelling and simulation of the converged process were conducted for fixed column variables (R = 5, N = 12 and p = 1 atm). Plant operating parameters were varied in the range of 0 to 1 for the pre-heater vapour fraction, 2 to 10 for the column feed plates (NFP), 2 to 6 …

Effect Of Zr And W Doping On Microstructures, Transition Temperature And Solar Transmittance Modulation Of Thermochromic W/Zr Co-Doped Vo2 Thin Films, Haji F. Haji

Tanzania Journal of Engineering and Technology (TJET)

Thermochromic W/Zr co-doped VO2-based thin films with different concentrations of Zr were successfully deposited on soda lime glass substrates by direct current (DC) magnetron sputtering of V(99)W(01) alloy and Zr targets at a substrate temperature of 425 °C. The films were characterized by x–ray diffraction (XRD), atomic force microscopy (AFM), Rutherford backscattering spectroscopy (RBS), two-point probe and UV/VIS/NIR spectroscopy. The film’s structural properties evolution was significantly influenced by Zr concentration in the films. The transition temperature and hysteresis loop widths of the films were found to decrease with increasing Zr concentration. For the Zr concentrations of 0.21 at.%, 0.23 at.% …

Sol-Gel Synthesis And Microstructure Characterization Of Nio-Tio2 Semiconductor, Godlisten N. Shao

Tanzania Journal of Engineering and Technology (TJET)

NiO-TiO2 is a fascinating p-n semiconducting binary metal oxide with unique electronic and optical properties. The NiO-TiO2 has been synthesized using complicated preparation methods and expensive precursors that hamper their large-scale production. The present study reports the preparation of NiO-TiO2 semiconductor with improved physicochemical properties. NiO-TiO2 samples were prepared through one-pot sol-gel synthesis process followed by sintering of the as-synthesized materials at temperatures ranging from 600 to 1000 °C. The role of thermal treatment and NiO content on the microstructures was exquisitely studied. The microstructure of the NiO-TiO2 samples was examined by Raman spectroscopy, XRD, XRF, SEM-EDAX, high resolution TEM, …

Sediment Characteristics And Hydrocarbon Composition Of Makukwa Seep In Southern Tanzania: Potential Implications For Subterranean Hydrocarbon Accumulation, Makungu M. Madirisha

Tanzania Journal of Engineering and Technology (TJET)

Exploring the interplay between natural seeps and nearby sediment and hydrocarbon properties is key to unlocking subsurface hydrocarbon potential. This study presents findings on the hydrocarbon composition and sediment characteristics of the Makukwa seep in southern Tanzania, providing insight into subterranean hydrocarbon accumulation. Sediment analysis across areas A and B, located approximately 20 m apart, showed a decrease in porosity with depth, indicative of typical sandstone formations. Area A, near the seeps, exhibited porosity ranging from 23% to 36%, whereas Area B, further away, showed porosity ranging from 22% to 38%. This suggests that a lower cretaceous sandstone layer may …

Production Of Biofertilizer From Fruit And Garden Waste, Neema Msuya

Tanzania Journal of Engineering and Technology (TJET)

The project focused on the production of bio-fertilizer from fruit and garden waste, with a specific emphasis on utilizing pineapple tops in the composting process. The objective was to produce and assess the properties of the bio fertilizer obtained from this process and evaluate its potential application in agriculture. In this study, the composting process was done in a 0.7 m long, 0.85 wide and 1.1 m high vessel, and 0.238 m3 pineapple top wastes, resulting in 0.35 m3 of biofertilizer. The bio fertilizer produced exhibited favorable characteristics, including a moisture content of 36%, pH of 7.1, and a total …

Assessment Of Risk Factors Related To Body Pain Complaints In Tanzania Construction Industry, Fatma K. Mohamed

Tanzania Journal of Engineering and Technology (TJET)

The construction industry is associated with risks that can result in musculoskeletal diseases. Although young male workers who are presumed to be healthy dominate the industry in Tanzania, body pain complaints have been widely reported. The aim of this study is to assess the prevalence and causes of body pains in workers. A cross-sectional study involving 396 workers was conducted. A chi square test was used for testing association of independent categorical variables and binary logistic regression analysis was used to determine predictors for body pain complaints. The results show that all study participants complained of at least one form …

Study Of The Effects Of Thermal Aging Coupled With Shot-Peening Treatment Of Carbonitrided Din 1.6587 Low Alloy Steel On Retained Austenite And Residual Stresses, Richard J. Katemi

Tanzania Journal of Engineering and Technology (TJET)

This work investigated the effects of thermal aging and shot-peening of carbonitrided 1.6587 steel grade on retained austenite and residual stresses. After carbonitriding samples contained maximum of 0.87% carbon, 0.34% nitrogen and 50 mass. -% retained austenite. Thermal aging conditions investigated were -30°C, 90°C and 150°C while the aging period were 14, 96 and 720 hours. After thermal aging, some of the samples were subjected to shot-peening treatment using standard cut wire shots StD – G3 - 0.6 mm VDFI 8001 with intensity in the range of 0.25 to 0.30 mmA and coverage of 1.00 to 1.24 x 98%. It …

Synthesis Of Local Control Systems For Underwater Units Cleaning Bottom Sediments In Reservoirs, Yuriy Gennadiyevich Shipulin, Zebiniso Akmalovna Zayniddinova

Chemical Technology, Control and Management

The article discusses the issues of synthesizing local control systems for underwater units for cleaning bottom sediments in reservoirs. It is shown that the protection and rational use of natural reservoirs and the fight against their premature siltation is becoming an urgent task.

It is proposed to use small-sized underwater units, consisting of information and measuring devices, to carry out search work for cleaning bottom sediments under water; control systems; actuators and means of communication with humans.

It is shown that the task of controlling the loading of an underwater unit (UU) requires maintaining optimal performance while simultaneously taking into …

Modernization Of Water Flow Measurement In Open Irrigation Systems Using The Slope-Area Method, R.M. Aliev, Djalilov Anvar

Chemical Technology, Control and Management

This article describes two methods for determining water flow in open irrigation systems: “speed - area” and “slope - area”. The authors considered the problem of its modernization using the existing method for determining water flow “slope - area” in open irrigation systems. The essence of the issue is the remote transfer of parameters necessary for calculating water flow in open irrigation systems and improving the means of their processing. In scientific studies conducted by the authors, the required hydraulic parameters were studied using the “slope - area” and “speed - area” water flow methods. Based on experimentally obtained data, …

Synthesis Algorithm Of Control System Based On Neural Network For The Gas And Oil Process, Jasur Sevinov, Abdishukurov Maqsudovich Shavkat, A.Z. Shodiyorov

Chemical Technology, Control and Management

Automatic control systems in the oil and gas processing are considered. After extraction of natural gas condensate, management of technological parameters plays an important role in its processing. Among the parameter of regulating algorithms, control based on neural network technology was considered. These control systems are created on the basis of algorithms of neural network technology. There are several structures of neural networks according to their structure. Differences in the process of information processing of these branching structures are considered.

Improving Technology For Producing Complex Fertilizer From Low-Grade Phosphorites Of The Central Kyzylkum, A.Zh. Allamuratova, A.U. Erkaev, A.M. Reimov, Saparbay Kazakhbaev, Dilshodbek Kurbiyazov

Chemical Technology, Control and Management

The methods of nitric acid processing of phosphate raw materials are analyzed. A technology has been developed for the nitric acid processing of phosphate raw materials into nitrogen-phosphorus fertilizer with the implementation of the process in a condensed pulp by adding sulfuric acid. A technology for producing complex fertilizers with a wide range of N:P₂O₅:K₂O ratios with improved physico-chemical parameters due to the introduction of various potassium salts into the process is proposed.

Dynamic Characteristics Of Magnetoelectric Linear Actuators Of Control Systems, Мakhmudjon Muxamedovich Аbdullayev, Rasul Ernazar Ogli Abdiev

Chemical Technology, Control and Management

This paper presents the results of studies carried out on magnetoelectric drives that carry out linear movement, models of drives are built and, on their basis, studies of the main indicators associated with the movement of a linear armature are carried out, such as: speed of movement, acceleration, current values, voltage and traction force of the armature. Also presented are the results of a study of magnetoelectric linear motion drives based on an analysis of graphs of their dynamic characteristics.

Algorithms For Structural Synthesis Of Control Systems For Dynamic Objects Under Conditions Of Unmeasurable Disturbances, Husan Zakirovich Igamberdiev, Uktam Farkhodovich Mamirov, Bunyod Mamurjon Ugli Buronov

Chemical Technology, Control and Management

The paper talks about ways to use inverse dynamic models to structure a control system for moving objects when disturbances are not measured. To solve the main problems that arise when implementing the inverse dynamic model method, methods for synthesizing inverse systems with given dynamic characteristics are used. The solution to this problem is obtained based on the theory that dynamic observers are invariant to unmeasured input influences. We broke down the matrix operator on the right into elementary orthogonal rotation matrices and on the left into permutation matrices to get a stable answer to the equation of the current …

Artificial Neural Network Based Grain Moisture Measuring Device, Erkin Eljaev, Shohrux Nurali O‘G‘Li Narzullayev, Elyor Faxriddinovich Khudoyberdiev

Chemical Technology, Control and Management

To date, the intellectualization of solving technical issues in managing, controlling, and measuring technological processes in all branches of industrial production is considered an urgent task. In this regard, a class of intelligent devices and sensors has emerged. Intelligent devices and sensors differ from their analog counterparts in that they have functions such as automatic adjustment of the measurement range, self-calibration, data processing, and decision-making. The article discusses the development of intelligent measuring instruments based on a capacitive transducer for measuring the moisture content of grain and grain products.

Valorization Of The Polymeric Constituents In Plastic Wastes Through Thermo-Chemical Processes By Using Viable Metal Oxides Additives, Labeeb Ali

Thesis/ Dissertation Defenses

The rapid accumulation of different types of plastic waste necessitates the development of effective and economically viable waste management operations. Such a process should ideally not only mitigate associated environmental burdens but also recycle and recover value-added products. Through incineration or pyrolysis, thermal processing has emerged as a mainstream approach to waste management of the ever-increasing loads of different categorized plastic wastes. Throughout the work of the thesis, we have utilized a multitude of complementary techniques spanning material characterizations, catalysis, kinetic modelling, and density functional theory (DFT) to comprehend the complex chemistry that underpins catalytic chemical recycling of plastic wastes. …