Chemical Engineering Commons^™

Ionic Liquid Pilocarpine Analog As An Antiglaucoma Drug Candidate, Juan Wang, Boxuan Li, Jing Tang, Li Qiu, Xin Qiao, Na Xu, Hu Yang

Chemical and Biochemical Engineering Faculty Research & Creative Works

Ionic liquid pilocarpine analog [Pilo-OEG]Cl, the first-of-its-kind ionic liquid antiglaucoma drug candidate, is synthesized and reported. To synthesize [Pilo-OEG]Cl, pilocarpine was reacted with the oligo-polyethylene glycol chloride, 2-[2-(2-chloroethoxy)ethoxy] ethanol, to form an ionic liquid molecule with an imidazole cation and a chloride anion. The chemical structure of [Pilo-OEG]Cl was confirmed with 1H NMR spectroscopy. Compared with pilocarpine (Pilo) and pilocarpine hydrochloride (PiloHCl), [Pilo-OEG]Cl has improved structural stability according to pH measurements and LC-MS analysis. The corneal permeability coefficient of [Pilo-OEG]Cl is 2-fold higher than that of Pilo and 8-fold higher than that of PiloHCl. [Pilo-OEG]Cl does not show apparent toxicity …

Development Of A Nanobiodegradable Drilling Fluid Using Prosopis Farcta Plant And Pomegranate Peel Powders With Metal Oxide Nanoparticles, Jagar A. Ali, Rawezh N. Ahmed, Abdullah D. Abdullah, Nali H. Ali, Abdullah M. Kalhury, Ayub N. Sabir, Abbas Khaksar Manshad, Alireza Keshavarz, Amir H. Mohammadi

Research outputs 2022 to 2026

One of the inevitable problems encountered during the petroleum well drilling process is "lost circulation"in which part of the drilling fluid is lost into the formation. A combination of nanoparticles with their unique properties and cost-effective biodegradable materials can play an effective role in treating fluid loss. In this study, our aim was to formulate drilling fluids modified with nanoparticles, pomegranate peel powder, and Prosopis farcta plant powder. The drilling fluids were identified and recognized using scanning electron microscopy, X-ray diffraction, and Fourier transform infrared spectroscopy techniques. Furthermore, experimental tests were conducted in order to investigate the performance of the …

Fabrications And Applications Of Micro/Nanofluidics In Oil And Gas Recovery: A Comprehensive Review, Junchen Liu, Yandong Zhang, Mingzhen Wei, Xiaoming He, Baojun Bai

Geosciences and Geological and Petroleum Engineering Faculty Research & Creative Works

Understanding fluid flow characteristics in porous medium, which determines the development of oil and gas oilfields, has been a significant research subject for decades. Although using core samples is still essential, micro/nanofluidics have been attracting increasing attention in oil recovery fields since it offers direct visualization and quantification of fluid flow at the pore level. This work provides the latest techniques and development history of micro/nanofluidics in oil and gas recovery by summarizing and discussing the fabrication methods, materials and corresponding applications. Compared with other reviews of micro/nanofluidics, this comprehensive review is in the perspective of solving specific issues in …

A Database Of Teleseismic Shear-Wave Splitting Measurements For The Ordos Block And Adjacent Areas, Lin Liu, Stephen S. Gao, Kelly H. Liu, Tu Xue, Yan Jia, Sanzhong Li

Geosciences and Geological and Petroleum Engineering Faculty Research & Creative Works

The Ordos block of the north China craton and its surrounding regions are affected by the India-Eurasia collision to the southwest and the subduction of the Pacific beneath the Eurasian plates to the east. To provide the foundation for delineating lithospheric deformation and asthenospheric flow beneath this tectonically diverse region, we have created a database of individual shear-wave splitting (SWS) parameters by applying a uniform set of data processing procedures. After automatic data processing and manual checking, a total of 16,228 pairs of well-defined PKS, SKKS, and SKS splitting parameters (fast orientations and splitting times) are obtained from 1023 broadband …

Crustal Structure And Subsidence Mechanisms Of The Williston Basin: New Constraints From Receiver Function Imaging, Jianguo Song, Stephen S. Gao, Kelly H. Liu, Muchen Sun, Youqiang Yu, Fansheng Kong, Kevin Mickus

Geosciences and Geological and Petroleum Engineering Faculty Research & Creative Works

Mechanisms responsible for the long-term subsidence of intracontinental basins such as the Williston Basin in North America remain enigmatic, partly due to the thick sedimentary layer commonly found in the basins that prevents reliably imaging the deep crustal and upper mantle structures using some of the most-commonly employed seismic methods such as receiver function analysis. In this study, we used receiver functions recorded by 274 USArray and other stations in the Williston Basin and adjacent areas to investigate the layered structure of the crust in the hydrocarbon-rich intracontinental basin. After the removal of strong reverberations on the receiver functions associated …

Estimating Flashpoints Of Fuels And Chemical Compounds Using Hybrid Machine-Learning Techniques, Farid Amirkhani, Amir Dashti, Hossein Abedsoltan, Amir H. Mohammadi, Abdoulmohammad Gholamzadeh Chofreh, Feybi Ariani Goni, Jiří Jaromír Klemeš

Chemical and Biochemical Engineering Faculty Research & Creative Works

Flashpoint of organic materials is a crucial physical property in industrial applications and laboratory experiments, which provides information on safety standards and needed precautions in handling various organic materials. Proposed methods to determine the flashpoint of an organic material suffer from dependency on other physical properties of the chemical or demand complicated calculations which are time-consuming. In this work, a direct system model is proposed to anticipate the flashpoints of organic materials for a wide range of chemical compounds. The following models of genetic algorithm-adaptive neuro-fuzzy inference system, the least-squares version of the support vector machine, particle swarm optimization-adaptive neuro-fuzzy …

Study On Apparent Permeability Model For Gas Transport In Shale Inorganic Nanopores, Shuda Zhao, Hongji Liu, Enyuan Jiang, Nan Zhao, Chaohua Guo, Baojun Bai

Geosciences and Geological and Petroleum Engineering Faculty Research & Creative Works

Inorganic nanopores occurring in the shale matrix have strong hydrophilicity and irreducible water (IW) film can be formed on the inner surface of the pores making gas flow mechanisms in the pores more complex. In this paper, the existence of irreducible water (IW) in inorganic pores is considered, and, based on the Knudsen number (K (Formula presented.)) correction in shale pores, a shale gas apparent permeability model of inorganic nano-pores is established. The effect of the K (Formula presented.) correction on the apparent permeability, the ratio of flow with pore radius and the effect of IW on the apparent permeability …

Renewable And Recyclable Polymeric Materials For Food Packaging: A New Open Special Issue In Materials, Shima Jafarzadeh, Masoumeh Zargar, Mehrdad Forough

Research outputs 2022 to 2026

“Renewable and Recyclable Polymeric Materials for Food Packaging” is a new open Special Issue of Materials that will publish original and review papers on new scientific and applied research, and the articles it contains will make a contribution to the discovery and understanding of biodegradable and recyclable materials, their functional properties, characterization and applications.

Li-Ion Electrode Microstructure Evolution During Drying And Calendering, Mojdeh Nikpour, Baichuan Liu, Paul Minson, Zachary Hillman, Brian A. Mazzeo, Dean R. Wheeler

Faculty Publications

The drying process of electrodes might seem to be a simple operation, but it has profound effects on the microstructure. Some unexpected changes can happen depending on the drying conditions. In prior work, we developed the multiphase-smoothed-particle (MPSP) model, which predicted a relative increase in the carbon additive and binder adjacent to the current collector during drying. This motivated us to undertake the present experimental investigation of the relationship between the drying rate and microstructure and transport properties for a typical anode and cathode. Specifically, the drying rate was controlled by means of temperature for both an NMC532 cathode and …

Effect Of Current Density Ramping On The Anodic Reaction And Morphology Of Aerospace Aluminum Alloys, Peter Totaro Jr.

Dissertations

Aluminum anodizing has been experimented with and studied over the last century because of its ability to form uniform, well ordered cellular coatings on aluminum alloys. Anodizing aerospace alloys has been problematic, due to the alloying elements used to add strength and resistance to stress cracking corrosion. These intermetallic compounds, i.e., copper and zinc, promote oxygen evolution and stress as they accumulate in and on the surface of the forming aluminum oxide. These inclusions lead to increased electrical resistance that forms porous and flawed coating, which can lead to industrial and field failures. The amount of voltage placed on the …

Effect Of Fluid Penetration On The Damage Processes And Microseismicity Due To The Hydraulic Fracturing Of Rocks, Catarina Baptista-Pereira

Dissertations

The hydraulic fracturing is used when fluids are injected inside the matrices of rocks to allow the creation of new cracks while, the propagation of the existent cracks can also occur. This process has been widely used for the past decades in the deep earth energy sector which comprises four main subsectors: 1) recovery of geothermal resources, 2) CO₂ and hydrogen sequestration; 3) wastewater and nuclear waste disposal, and 4) recovery of (non)conventional fluids. By creating new flow paths or enhancing the existing ones, the pores are allowed to connect and, thus, it increases the permeability of rocks. For …

Evaluation Of Material Request Order To Support Sustainable Construction, Fajar Susilowati, Nur Nahdiah Anggraeni

Makara Journal of Technology

This study was conducted on one of Indonesia’s apartment projects, in which reinforced concrete is the main structure. Based on existing project data, this project experienced a decline in the construction work’s progress, thus reducing the project’s overall progress. This decline occurred because the delivery of concrete reinforcement material was delayed. This study aimed to determine the process of material request order and its relationship with the work implementation, as well as the factors that influenced the delayed arrival of concrete reinforcement material at the project site. The method used in this study was observation and interview. Data were analyzed …

Effects Of Various Solvents On Adsorption Of Organics For Porous And Nonporous Quartz Co2 Brine Systems: Implications For Co2 Geo-Storage, Muhammad Ali, Nurudeen Yekeen, Mujahid Ali, Mirhasan Hosseini, Nilanjan Pal, Alireza Keshavarz, Stefan Iglauer, Hussein Hoteit

Research outputs 2022 to 2026

The underground geo-storage of carbon dioxide (CO₂) is an essential component of the carbon capture and sequestration value chain. The success of CO₂ containment depends on the wetting state of the rock, which controls the mechanism of fluid flow and distribution. The presence of organic acids in the storage formation introduces a considerable effect on the wettability of the rock / CO₂ / brine system under various temperature and pressure conditions. Despite the previous studies on this topic, the impact of the substrate pores, the rock surface roughness, and the solvents used to prepare the organic …

Low-Crystallinity And Heterostructured Aupt-Ru@Cnts As Highly Efficient Multifunctional Electrocatalyst, Tuan-Jie Gan, Jian-Ping Wu, Shi Liu, Wen-Jun Ou, Ling Bin, Xiong-Wu Kang

Journal of Electrochemistry

The catalytic activity of the catalysts is strongly dependent on the structure of the catalysts, and the exploration of their correlation and structure-controlled synthesis of the high-performance catalysts are always at the central. Currently, platinum (Pt) is the optimum catalyst for hydrogen evolution reaction (HER), oxygen reduction reaction (ORR) and alcohol oxidation reaction, while ruthenium (Ru) behaves as the champion catalyst for oxygen evolution reaction (OER) during water splitting. Preparing alloy catalysts with these precious metals can modulate the catalytic activity of these catalysts from the perspective of strain effect, ensemble effect and ligand effect. Here, we developed a strategy …

Facile One-Step Solid-State Synthesis Of Ni-Rich Layered Oxide Cathodes For Lithium-Ion Batteries, Jing-Yue Wang, Rui Wang, Shi-Qi Wang, Li-Fan Wang, Chun Zhan

Journal of Electrochemistry

Nickel-rich layered oxide is one of the dominate cathode materials in the lithium ion batteries, due to its high specific energy density meeting the range requirement of the electric vehicles. Typically, the commercial Ni-rich layered oxides are synthesized from co-precipitated precursors, while precision control is required in the co-precipitation process to ensure the atomic level mixing of the cations such as Ni, Co and Mn, et.al. In this work, a one-step solid-state method was successfully applied to synthesize the Ni-rich layered oxide materials with ultra-high Ni content. By choosing the nickel hydroxides as the precursor with layered structure similar to …

Modeling Solvent Extraction Of Lignin From Hardwoods, Su Pan

McKelvey School of Engineering Graduate Student Theses & Dissertations

This study interprets the observed behavior of solvent extraction of lignin from hardwoods by adapting the framework of the FLASHCHAIN theory (Niksa and Kerstein, 1991; Niksa, 2017). A constitution submodel specifies distributions of molecular weight and reactive sites for native lignin. The model simulates delignification as depolymerization of lignin macromolecules into fragments small enough to be soluble. This process competes with intrachain condensation that consumes labile bridges without forming new fragments, and with recombination that forms larger chains and inhibits further depolymerization. After the soluble fragments are transported from the particle into the bulk solvent, all chemistry continues as long …

Identification Of Lithocholic Acid As A Molecular Glass Host For Room-Temperature Phosphorescent Materials, John J. Flynn, Zachary M. Marsh, Douglas M. Krein, Steven M. Wolf, Joy E. Haley, Erick S. Vasquez, Thomas M. Cooper, Nicholas P. Godman, Tod A. Grusenmeyer

Chemical and Materials Engineering Faculty Publications

Lithocholic acid was identified as a molecular glass host material for room temperature phosphorescent (RTP) chromophores. Differential scanning calorimetry (DSC) was performed on a series of structurally similar, biologically sourced molecules, including lithocholic acid, β-estradiol, cholesterol, and β-sitosterol, in an effort to identify new amorphous molecular glasses independent of plasticizing additives. DSC analysis revealed lithocholic acid and β-estradiol form stable molecular glasses post thermal processing unlike neat cholesterol and β-sitosterol. The ability of lithocholic acid and β-estradiol to stabilize high wt. % loadings of d10-pyrene and a mixture of d10-pyrene and an iridium chromophore, bis(2,4-difluorophenylpyridinato)-tetrakis(1-pyrazolyl)borate iridium(III) (FIr6), was also investigated. …

Thermo-Responsive Hydrophilic Support For Polyamide Thin-Film Composite Membranes With Competitive Nanofiltration Performance, Haniyeh Najafvand Drikvand, Mitra Golgoli, Masoumeh Zargar, Mathias Ulbricht, Siamak Nejati, Yaghoub Mansourpanah

Research outputs 2022 to 2026

Poly(N-isopropylacrylamide) (PNIPAAm) was introduced into a polyethylene terephthalate (PET) nonwoven fabric to develop novel support for polyamide (PA) thin-film composite (TFC) membranes without using a microporous support layer. First, temperature-responsive PNIPAAm hydrogel was prepared by reactive pore-filling to adjust the pore size of non-woven fabric, creating hydrophilic support. The developed PET-based support was then used to fabricate PA TFC membranes via interfacial polymerization. SEM–EDX and AFM results confirmed the successful fabrication of hydrogel-integrated non-woven fabric and PA TFC membranes. The newly developed PA TFC membrane demonstrated an average water permeability of 1 L/m2 h bar, and an NaCl rejection of …

Machining Of Carbon Steel Under Aqueous Environment: Investigations Into Some Performance Measures, Mushtaq Ali, Tahir Abdul Hussain Ratlamwala, Ghulam Hussain, Tauheed Shehbaz, Riaz Muhammad, Muhammad Aamir, Khaled Giasin, Danil Yurievich Pimenov

Research outputs 2022 to 2026

In this study, a new machining approach (aqueous machining) is applied for mill machining and its performance is compared with traditional wet machining. AISI 1020 steel is employed as the test material and Taguchi statistical methodology is implemented to analyze and compare the performance of the two machining approaches. The cutting speed, feed rate, and depth of cut were the machining parameters used for both types of machining, while the selected response variables were surface roughness and hardness. Temperature variations were also recorded in aqueous machining. Compared with wet machining, aqueous machining resulted in lower surface roughness (up to 13 …

Myosin Ii Adjusts Motility Properties And Regulates Force Production Based On Motor Environment, Omayma Y. Al Azzam, Janie C. Watts, Justin E. Reynolds, Juliana E. Davis, Dana N. Reinemann

Faculty and Student Publications

Introduction—Myosin II has been investigated with optical trapping, but single motor-filament assay arrangements are not reflective of the complex cellular environment. To understand how myosin interactions propagate up in scale to accomplish system force generation, we devised a novel actomyosin ensemble optical trapping assay that reflects the hierarchy and compliancy of a physiological environment and is modular for interrogating force effectors.

Methods—Hierarchical actomyosin bundles were formed in vitro. Fluorescent template and cargo actin filaments (AF) were assembled in a flow cell and bundled by myosin. Beads were added in the presence of ATP to bind the cargo AF …

Study Of Water Desalination: A Persian Gulf City, Grégoire Saury

Student Theses and Dissertations

Water desalination represents an important challenge of tomorrow’s world. Water needs never stop to increase and certain areas of the world relies on ways to have access to this resource. Desalination is a process that offers an alternative access to this vital resource by using seawater as process input. These installations are implementing several purifications units designed to transform seawater into drinkable water. So, they eliminate salt but also any kind of pollution present in the water. Here, the goal will be to design a process able to provide drinkable water for a 200,000 habitants town located in the Persian …

Preface Of Volume 1 Issue 1 On Journal Of Materials Exploration And Findings (Jmef), Jaka Fajar Fatriansyah

Journal of Materials Exploration and Findings

No abstract provided.

The Optimization Of Failure Risk Estimation On The Uniform Corrosion Rate With A Non-Linear Function, Fernanda Hartoyo, Jaka Fajar Fatriansyah, Imam Abdillah Mas'ud, Farhan Rama Digita, Hanna Ovelia, D. Rizal Asral

Journal of Materials Exploration and Findings

Failures in the oil and gas pipeline system are conditions that must be avoided and anticipated because the losses due to the failures can occur at a very high level. Internal corrosion is one of the significant causes of the failures in pipeline systems. In addition, this type of corrosion is due to the high content of carbon dioxide and other corrosive substances in crude oil and natural gas. Therefore, an optimal inspection scheduling system is required to prevent the possibility of pipeline failures due to corrosion and to avoid any overspending on the budget due to excessive inspection scheduling. …

Contents, Jaka Fajar Fatriansyah

Journal of Materials Exploration and Findings

No abstract provided.

Advancing Water Resource Assessment With Insar Data And Subsidence Models, Ryan G. Smith

Geosciences and Geological and Petroleum Engineering Faculty Research & Creative Works

Over the past three decades, Interferometric Synthetic Aperture Radar (InSAR) has grown from a tool for monitoring earthquakes and other massive signature deformation events to tracking the subtle, slow deformation processes associated with changes in groundwater storage. Improvements in time-series processing and noise reduction, as well as improved models of deformation, have enabled this advancement. InSAR has proven to be a valuable tool for characterizing elastic deformation in regions experiencing little long-term storage loss, as well as inelastic deformation in over-stressed aquifers.

Dynamics Of Spatiotemporal Heterogeneities In Particulate Intercalation Electrodes, Shubham Agrawal

McKelvey School of Engineering Graduate Student Theses & Dissertations

Electrochemical energy systems rely on particulate porous electrodes to store or convert energies. While the three-dimensional porous structures of the electrodes were introduced to maximize the interfacial area for better overall performance of the system, spatiotemporal heterogeneities arising from materials thermodynamics localize the charge transfer processes onto a limited portion of the available interfaces. These reaction heterogeneities may cause local hot and cold spots, and early battery failures. This dissertation focuses on the following three aspects of the dynamic reaction heterogeneities in the particulate cathodes and anodes in the lithium-ion batteries: (i) the real-time evolution of reaction heterogeneities in graphite …

Nano-Bio Interactions: Implications And Applications, Anushree Ghosh

McKelvey School of Engineering Graduate Student Theses & Dissertations

Rapid expansion of technology development at the nanoscale has underpinned a promising industry. Towards this, there remain significant information gaps which are critical with regard to decision making processes and ultimate industrial sustainability. From an implication point of view, understanding how common biological macromolecules, including glycolipids and/or biopolymers produced by bacteria and fungi, which are ubiquitous in the environment, is fundamental to predicting the behavior of released/produced nanoparticles. Conversely, other bio-based tailored macromolecules, including mussel foot protein (MFP), have significant potential as functional material coatings for advanced applications.This PhD thesis is focused on interfacial processes related to superparamagnetic iron oxide …

Nanoscale Interfacial Control Of Ion Behaviors And Caco3 Formation In Environmental Systems, Yaguang Zhu

McKelvey School of Engineering Graduate Student Theses & Dissertations

Interfaces in environmental systems can change the distribution of pollutants and nutrients, determine the fate and transport of nanoparticles, and affect the efficiency of engineering projects. Complex interactions, including electrostatic interactions, Van der Waals interactions, chemical interactions, and ion-surface specific interactions, can all contribute to different ion, ion-pair, and nanoparticle formations near interfaces. Although environmental interfaces play critical roles, only a limited number of studies have considered the nanoscale picture of how they control ions and nanoparticles. Thus, this dissertation addresses three research questions: (1) How does sulfate chemically interact with calcium carbonate (CaCO3) during its heterogeneous formation on quartz …

The Generation And Transport Of Charged Aerosols: Fundamental Study And Applications In Medicine And Energy Conversion, Hao Zhou

McKelvey School of Engineering Graduate Student Theses & Dissertations

Charged aerosols have significant implications in the field of functional material synthesis, pharmaceutical coating, and drug delivery. Electrospray systems are an effective methodology for generating highly charged monodispersed droplets in the size range from nanometer to micrometer. The prediction of surface charge, size and morphology of nanoparticles resulting from charged droplets are highly required for the precise control of nanoparticle properties and their effective utilization. However, the evolution of charged droplet is not well understood due to the existence of coulombic fission and ion evaporation processes. Thus, the goal of this dissertation is to elucidate how the precursor properties and …

Lead(Iv) Oxide In Drinking Water Systems: Formation, Dissolution, Redox-Driven Recrystallization, And Implications For Lead Control, Weiyi Pan

McKelvey School of Engineering Graduate Student Theses & Dissertations

Lead (Pb) in tap water is mainly contributed by lead service lines (LSLs). The dissolved lead concentration is controlled by the solubilities of lead corrosion products that form on the inner surface of LSLs. Among these lead corrosion products, lead(IV) oxide (PbO2) has the lowest solubility and can maintain a low lead level when free chlorine is present. Current strategies to control the lead concentration include replacing the LSL, optimizing the water chemistry conditions, and using point-of-use (POU) filters. The present study investigated the effect of manganese (Mn) on the oxidation of the lead(II) carbonate solids by free chlorine, the …