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Articles 211 - 240 of 823
Full-Text Articles in Chemical Engineering
In Vivo Analysis Of A Proprietary Glass-Based Adhesive For Sternal Fixation And Stabilization Using Rabbit And Sheep Models, Cina Mehrvar, Emily Deignan, Mark Hurtig, Gideon Cohen, Paul Zalzal, Oleg Safir, Adel Alhalawani, Marcello Papini, Mark R. Towler
In Vivo Analysis Of A Proprietary Glass-Based Adhesive For Sternal Fixation And Stabilization Using Rabbit And Sheep Models, Cina Mehrvar, Emily Deignan, Mark Hurtig, Gideon Cohen, Paul Zalzal, Oleg Safir, Adel Alhalawani, Marcello Papini, Mark R. Towler
Chemical and Biochemical Engineering Faculty Research & Creative Works
Wire cerclage remains the standard method of care for sternal fixation, following median sternotomy, despite being beset with complications. An emerging treatment option has been to augment the wires with an adhesive. A patented ionomeric glass (mole fraction: SiO2:0.48, ZnO:0.36, CaO:0.12, SrO:0.04) has been used to formulate GPC+, a glass polyalkenoate cement (GPC), by mixing it with poly(acrylic) acid (PAA) and de-ionized water. In a human cadaver study, this material, when applied with wire cerclage, was able to significantly reduce sternal instability. However, the material has yet to be tested in pertinent animal models. Here, after a series …
Laboratory-Scale Research Of Non-Catalyzed Supercritical Alcohol Process For Continuous Biodiesel Production, Aso A. Hassan, Joseph D. Smith
Laboratory-Scale Research Of Non-Catalyzed Supercritical Alcohol Process For Continuous Biodiesel Production, Aso A. Hassan, Joseph D. Smith
Chemical and Biochemical Engineering Faculty Research & Creative Works
This work investigates the non-catalyzed supercritical methanol (SCM) process for continuous biodiesel production. The lab-scale setup was designed and used for biodiesel production in the temperature range of 520–650 K and 83–380 bar with an oil-to-methanol molar ratio ranging from 1:5 to 1:45. The experiments were performed in the coiled plug flow tubular reactor. The volumetric flow rate of the methanol/oil ranged from 0.1-10 mL/min. This work examines a new reactor technology involving preheating and pre-mixing of the methanol/oil mixture to reduce setup cost and increase biodiesel yield under the same reaction conditions. Work performed showed that FAME’s yield increased …
Gagrank: Software For Glycosaminoglycan Sequence Ranking Using A Bipartite Graph Model, John D. Hogan, Jiandong Wu, Joshua A. Klein, Cheng Lin, Luis Carvalho, Joseph Zaia
Gagrank: Software For Glycosaminoglycan Sequence Ranking Using A Bipartite Graph Model, John D. Hogan, Jiandong Wu, Joshua A. Klein, Cheng Lin, Luis Carvalho, Joseph Zaia
Chemical and Biochemical Engineering Faculty Research & Creative Works
The Sulfated Glycosaminoglycans (GAGs) Are Long, Linear Polysaccharide Chains that Are Typically Found as the Glycan Portion of Proteoglycans. These GAGs Are Characterized by Repeating Disaccharide Units with Variable Sulfation and Acetylation Patterns Along the Chain. GAG Length and Modification Patterns Have Profound Impacts on Growth Factor Signaling Mechanisms Central to Numerous Physiological Processes. Electron Activated Dissociation Tandem Mass Spectrometry is a Very Effective Technique for Assigning the Structures of GAG Saccharides; However, Manual Interpretation of the Resulting Complex Tandem Mass Spectra is a Difficult and Time-Consuming Process that Drives the Development of Computational Methods for Accurate and Efficient Sequencing. …
Acute Dose-Dependent Neuroprotective Effects Of Poly(Pro-17Β-Estradiol) In A Mouse Model Of Spinal Contusion Injury, Manoj K. Gottipati, Samuel A.T. Ellman, Devan L. Puhl, Zhen Guan, Phillip G. Popovich, Edmund F. Palermo, Ryan J. Gilbert
Acute Dose-Dependent Neuroprotective Effects Of Poly(Pro-17Β-Estradiol) In A Mouse Model Of Spinal Contusion Injury, Manoj K. Gottipati, Samuel A.T. Ellman, Devan L. Puhl, Zhen Guan, Phillip G. Popovich, Edmund F. Palermo, Ryan J. Gilbert
Chemical and Biochemical Engineering Faculty Research & Creative Works
17β-Estradiol (E2) confers neuroprotection in preclinical models of spinal cord injury when administered systemically. The goal of this study was to apply E2 locally to the injured spinal cord for a sustained duration using poly(pro-E2) film biomaterials. Following contusive spinal cord injury in adult male mice, poly(pro-E2) films were implanted subdurally and neuroprotection was assessed using immunohistochemistry 7 days after injury and implantation. In these studies, poly(pro-E2) films modestly improved neuroprotection without affecting the inflammatory response when compared to the injured controls. To increase the E2 dose released, bolus-releasing poly(pro-E2) films were fabricated by incorporating unbound E2 into the poly(pro-E2) …
Translational Implications Of The Interactions Between Hormones And Age-Related Hearing Loss, R. D. Frisina, Parveen Bazard, M. Bauer, J. Pineros, X. Zhu, B. Ding
Translational Implications Of The Interactions Between Hormones And Age-Related Hearing Loss, R. D. Frisina, Parveen Bazard, M. Bauer, J. Pineros, X. Zhu, B. Ding
Chemical and Biochemical Engineering Faculty Research & Creative Works
Provocative research has revealed both positive and negative effects of hormones on hearing as we age; with in some cases, mis-regulation of hormonal levels in instances of medical comorbidities linked to aging, lying at the heart of the problem. Animal model studies have discovered that hormonal fluctuations can sharpen hearing for improved communication and processing of mating calls during reproductive seasons. Sex hormones sometimes have positive effects on auditory processing, as is often the case with estrogen, whereas combinations of estrogen and progesterone, and testosterone, can have negative effects on hearing abilities, particularly in aging subjects. Too much or too …
Conventional Immunomarkers Stain A Fraction Of Astrocytes In Vitro: A Comparison Of Rat Cortical And Spinal Cord Astrocytes In Naïve And Stimulated Cultures, Bailey Balouch, Jessica L. Funnell, Alexis M. Ziemba, Devan L. Puhl, Kathy Lin, Manoj K. Gottipati, Ryan J. Gilbert
Conventional Immunomarkers Stain A Fraction Of Astrocytes In Vitro: A Comparison Of Rat Cortical And Spinal Cord Astrocytes In Naïve And Stimulated Cultures, Bailey Balouch, Jessica L. Funnell, Alexis M. Ziemba, Devan L. Puhl, Kathy Lin, Manoj K. Gottipati, Ryan J. Gilbert
Chemical and Biochemical Engineering Faculty Research & Creative Works
Astrocytes are responsible for a wide variety of essential functions throughout the central nervous system. The protein markers glial fibrillary acidic protein (GFAP), glutamate aspartate transporter (GLAST), glutamate transporter-1 (GLT-1), glutamine synthetase (GS), 10-formyltetrahydrofolate dehydrogenase (ALDH1L1), and the transcription factor SOX9 are routinely used to label astrocytes in primary rodent cultures. However, GLAST, GLT-1, GS, and SOX9 are also produced by microglia and oligodendrocytes and GFAP, GLAST, GLT-1, and GS production levels are affected by astrocyte phenotypic changes associated with reactive astrogliosis. No group has performed a comprehensive immunocytochemical evaluation to quantify the percentage of cells labeled by these markers …
In Vitro Evaluation Of Novel Titania-Containing Borate Bioactive Glass Scaffolds, Romina Shafaghi, Omar Rodriguez, Anthony W. Wren, Loraine Chiu, Emil H. Schemitsch, Paul Zalzal, Stephen D. Waldman, Marcello Papini, Mark R. Towler
In Vitro Evaluation Of Novel Titania-Containing Borate Bioactive Glass Scaffolds, Romina Shafaghi, Omar Rodriguez, Anthony W. Wren, Loraine Chiu, Emil H. Schemitsch, Paul Zalzal, Stephen D. Waldman, Marcello Papini, Mark R. Towler
Chemical and Biochemical Engineering Faculty Research & Creative Works
Titanium-containing borate bioactive glass scaffolds (0, 5, 15, and 20 mol %, identified as BRT0, BRT1, BRT3, and BRT4) with a microstructure similar to that of human trabecular bone were prepared and evaluated in vitro for potential bone loss applications in revision total knee arthroplasty (rTKA). Methyl thiazolyl tetrazolium (MTT) cell viability assays of scaffold ion release extracts revealed that BRT0 scaffolds (0 mol % titanium) inhibited cell proliferation and activity at day 14. At day 30, all scaffold extracts decreased cell proliferation and activity significantly. However, live/dead cell assay results demonstrated that degradation products from all the scaffolds had …
Lignin-Zein Composite: Synthesis, Three-Dimensional Printing, And Microbial Degradation, Jin Gyun Lee, Yusheng Guo, Jorge A. Belgodere, Ahmed Al Harraq, Aubry A. Hymel, Amber J. Pete, Kalliat T. Valsaraj, Michael G. Benton, Mary G. Miller, Jangwook P. Jung, Bhuvnesh Bharti
Lignin-Zein Composite: Synthesis, Three-Dimensional Printing, And Microbial Degradation, Jin Gyun Lee, Yusheng Guo, Jorge A. Belgodere, Ahmed Al Harraq, Aubry A. Hymel, Amber J. Pete, Kalliat T. Valsaraj, Michael G. Benton, Mary G. Miller, Jangwook P. Jung, Bhuvnesh Bharti
Chemical and Biochemical Engineering Faculty Research & Creative Works
Worldwide use and disposal of plastics have reached a dramatic saturation point, polluting lands, oceans, and air across the globe. Responding to such a challenge requires, among other environmental remediation measures, the manufacture of alternative sustainable plastics. Recent studies in the area have enabled the development of degradable plastics; however, the rate and conditions required for the degradation of such materials remains under scrutiny. Here, we introduce a new class of fully plant-based, rapidly degradable lignin and zein composite blend that can be transformed into macroscopic structures using extrusion three-dimensional (3D) printing. Corn-derived zein forms the polymeric solution, while insoluble …
Bone Cement As A Local Chemotherapeutic Drug Delivery Carrier In Orthopedic Oncology: A Review, Sunjeev S. Phull, Alireza Rahimnejad Yazdi, Michelle Ghert, Mark R. Towler
Bone Cement As A Local Chemotherapeutic Drug Delivery Carrier In Orthopedic Oncology: A Review, Sunjeev S. Phull, Alireza Rahimnejad Yazdi, Michelle Ghert, Mark R. Towler
Chemical and Biochemical Engineering Faculty Research & Creative Works
Metastatic bone lesions are common among patients with advanced cancers. While chemotherapy and radiotherapy may be prescribed immediately after diagnosis, the majority of severe metastatic bone lesions are treated by reconstructive surgery, which, in some cases, is followed by postoperative radiotherapy or chemotherapy. However, despite recent advancements in orthopedic surgery, patients undergoing reconstruction still have the risk of developing severe complications such as tumor recurrence and reconstruction failure. This has led to the introduction and evaluation of poly (methyl methacrylate) and inorganic bone cements as local carriers for chemotherapeutic drugs (usually, antineoplastic drugs (ANPDs)). The present work is a critical …
Mixed Matrix Membranes For Sustainable Electrical Energy-Saving Applications, Hossein Riasat Harami, Farid Amirkhani, Hossein Abedsoltan, Mohammad Younas, Mashallah Rezakazemi, Mahdi Sheikh, Saeed Shirazian
Mixed Matrix Membranes For Sustainable Electrical Energy-Saving Applications, Hossein Riasat Harami, Farid Amirkhani, Hossein Abedsoltan, Mohammad Younas, Mashallah Rezakazemi, Mahdi Sheikh, Saeed Shirazian
Chemical and Biochemical Engineering Faculty Research & Creative Works
This work presents a technical investigation and review of the development of mixed matrix membranes (MMMs) employed in different applications to save electrical energy. The MMMs design has been recently adjusted and improved to restore more energy bulks. The important factors to control the performance of the MMMs are the penetrant type, membrane matrix, and polymer-filler interface interactions. This study reviews the current methods to deal with dielectric MMMs and smart nanomembranes for energy saving. These methods include ferroelectric membrane fabrication, dielectric permittivity, conductive dopants, construction of nanocomposites with modified surfaces, and the usage of combined effects. Most chemists and …
Fluorination Of Al₂O₃ Coating For Lithium-Ion Battery, Xinhua Liang, Han Yu
Fluorination Of Al₂O₃ Coating For Lithium-Ion Battery, Xinhua Liang, Han Yu
Chemical and Biochemical Engineering Faculty Research & Creative Works
Improving the performance of cathodes by using surface coatings has proven to be an effective method for improving the stability of Li-ion batteries (LIBs), while a high quality film satisfying all requirements of electrochemical inertia, chemical stability, and lithium ion conductivity has not been found. A composite film composed of AI2O3 and AIF3 layers was coated on the surface of Li-rich NMC based electrodes by atomic layer deposition (ALD). The electrochemical characterization results indicated that the coating with 1 cycle of AIF3 ALD on 5 cycles of AI2O3 ALD (1 A1 F3-5AI2O …
Coating Compositions And Methods For Using The Same, Fateme Rezaei, Thomas P. Schuman, Glenn Morrison
Coating Compositions And Methods For Using The Same, Fateme Rezaei, Thomas P. Schuman, Glenn Morrison
Chemical and Biochemical Engineering Faculty Research & Creative Works
Coating compositions and methods for using the same are disclosed. The coating compositions can include an aminosilica adsorbent. The coating compositions can adsorb CO2.
Isolation And Purification Of Glycoglycerolipids To Induce Apoptosis In Breast Cancer Cells, Muhammad Raisul Abedin, Sutapa Barua
Isolation And Purification Of Glycoglycerolipids To Induce Apoptosis In Breast Cancer Cells, Muhammad Raisul Abedin, Sutapa Barua
Chemical and Biochemical Engineering Faculty Research & Creative Works
Monogalactosyldiacylglycerol (MGDG) is the most abundant type of glycoglycerolipid found in the plant cell membrane and mostly in the chloroplast thylakoid membrane. The amphiphilic nature of MGDG is attractive in pharmaceutical fields for interaction with other biological molecules and hence exerting therapeutic anti-cancer, anti-viral, and anti-inflammatory activities. In this study, we investigated the therapeutic efficacy of cyanobacteria derived MGDG to inhibit breast cancer cell growth. MGDG was extracted from a cyanobacteria Synechocystis sp. PCC 6803 followed by a subsequent fractionation by column chromatographic technique. The purity and molecular structure of MGDG were analyzed by nuclear magnetic resonance (NMR) spectroscopy analysis. …
The 3-O-Sulfation Of Heparan Sulfate Modulates Protein Binding And Lyase Degradation, Pradeep Chopra, Apoorva Joshi, Jiandong Wu, Weigang Lu, Tejabhiram Yadavalli, Margreet A. Wolfert, Deepak Shukla, Joseph Zaia, Geert Jan Boons
The 3-O-Sulfation Of Heparan Sulfate Modulates Protein Binding And Lyase Degradation, Pradeep Chopra, Apoorva Joshi, Jiandong Wu, Weigang Lu, Tejabhiram Yadavalli, Margreet A. Wolfert, Deepak Shukla, Joseph Zaia, Geert Jan Boons
Chemical and Biochemical Engineering Faculty Research & Creative Works
Humans Express Seven Heparan Sulfate (HS) 3-O-Sulfotransferases that Differ in Substrate Specificity and Tissue Expression. Although Genetic Studies Have Indicated that 3-O-Sulfated HS Modulates Many Biological Processes, Ligand Requirements for Proteins Engaging with HS Modified by 3-O-Sulfate (3-OS) Have Been Difficult to Determine. in Particular, the Context in Which the 3-OS Group Needs to Be Presented for Binding is Largely Unknown. We Describe Herein a Modular Synthetic Approach that Can Provide Structurally Diverse HS Oligosaccharides with and Without 3-OS. the Methodology Was Employed to Prepare 27 Hexasaccharides that Were Printed as a Glycan Microarray to Examine Ligand Requirements of a …
Enhancing Emulsion Liquid Membrane System (Elm) Stability And Performance For The Extraction Of Phenol From Wastewater Using Various Nanoparticles, Faris H. Al-Ani, Qusay F. Alsalhy, Muthanna H. Al-Dahhan
Enhancing Emulsion Liquid Membrane System (Elm) Stability And Performance For The Extraction Of Phenol From Wastewater Using Various Nanoparticles, Faris H. Al-Ani, Qusay F. Alsalhy, Muthanna H. Al-Dahhan
Chemical and Biochemical Engineering Faculty Research & Creative Works
Emulation liquid membrane (ELM) technology has recently garnered attention as an efficient alternative for separating pollutants, but it faces the problem of instability during the application, as well as emulsion breaking. With this in mind MgO, Al2O3, and three magnetic Fe2O3 nanoparticles (of different sizes) were utilized to fabricate a new Pickering ELM system (PELM). The extraction efficiency of phenol from aqueous solution by PELM was studied with different NPs types and with different phenol concentrations (1,000; 500; 100; and 50 ppm). It was found that the type of NPs and concentration of …
Water Absorption Enhancement Of Sodium Poly Acrylate And Poly(2-Acrylamido-2-Methylpropane Sulphonic Acid) Based Hydrogel Mixtures, Sohair A. Darwish, Ibrahim M. Ibrahim, Nasser Y. Mostafa, Mostafa A. Radwan, Mohamed A. Sadek, Hany A. Elazab
Water Absorption Enhancement Of Sodium Poly Acrylate And Poly(2-Acrylamido-2-Methylpropane Sulphonic Acid) Based Hydrogel Mixtures, Sohair A. Darwish, Ibrahim M. Ibrahim, Nasser Y. Mostafa, Mostafa A. Radwan, Mohamed A. Sadek, Hany A. Elazab
Chemical and Biochemical Engineering Faculty Research & Creative Works
Introduction: Hydrogels are hydrophilic polymers which are cross-linked to form three-dimensional structures, which can absorb, swell and retain huge amounts of water or aqueous fluids. Objective: This paper reports the preparation and characterization of Poly (2-Acrylamido-2-Methylpropane Sulphonic Acid) (PAMPS) hydrogel with different crosslinking intensities. Methodology: 2-Acrylamido-2-methylpropane sulfonic acid (AMPS) monomer was purchased from Alfa Aesar Company as reagent grade. It was used as received (>98% purity) without any further purification. PAMPS hydrogel was prepared by free radical crosslinking solution polymerization of AMPS in water at room temperature under a nitrogen blanket in cylindrical glass tubes. The characteristics of the …
Better Heat And Power Integration Of An Existing Gas-Oil Plant In Egypt Through Revamping The Design And Organic Rankine Cycle, Mamdouh A. Gadalla, Alaa Elmasry, Ibrahim Alhajri, Fatma H. Ashour, Hany A. Elazab
Better Heat And Power Integration Of An Existing Gas-Oil Plant In Egypt Through Revamping The Design And Organic Rankine Cycle, Mamdouh A. Gadalla, Alaa Elmasry, Ibrahim Alhajri, Fatma H. Ashour, Hany A. Elazab
Chemical and Biochemical Engineering Faculty Research & Creative Works
Objective: The current study aims mainly to Maximize Condensate Recovery (NGLs), focusing on a gas processing train of Gas-Oil Separation Plant (GOSP) located in Egypt with a capacity of 4,230 kmole/h. Methods: The research study accounts for the constraint of Reid Vapor Pressure (RVP) specification, which makes the storage in floating roof tanks is of a great risk. The study proposes the installation of the cryogenic train that recovers condensates (C4+). This train comprises of compression unit, expansion unit, three-phase separators and a re-boiled absorber. The problem of RVP will no longer exist because of the re-boiled absorber achieving RVP …
Equilibrium And Kinetic Study On The Biosorption Of Trypan Blue From Aqueous Solutions Using Avocado Seed Powder, Tamer T. El-Idreesy, Omar Khoshala, Amin Firouzi, Hany A. Elazab
Equilibrium And Kinetic Study On The Biosorption Of Trypan Blue From Aqueous Solutions Using Avocado Seed Powder, Tamer T. El-Idreesy, Omar Khoshala, Amin Firouzi, Hany A. Elazab
Chemical and Biochemical Engineering Faculty Research & Creative Works
This research aims to investigate the removal of trypan blue dye from aqueous solutions by employing ground avocado seeds powder, a low-cost biowaste adsorbent (biosorbent), under various experimental conditions. The effect of contact time, initial dye concentration, and adsorbent dose on dye removal were studied. The experimental kinetic data were fitted to pseudo-first order and pseudo-second-order kinetic models. Results imply that adsorption of trypan blue on the avocado seed adsorbent nicely followed the pseudo-second-order kinetic model. Equilibrium isotherms were analyzed by Langmuir and Freundlich isotherms, where Langmuir isotherm described the isotherm data with a high-correlation coefficient (R2=0.9948) closer to unity, …
Electrospun Fiber Scaffolds For Engineering Glial Cell Behavior To Promote Neural Regeneration, Devan L. Puhl, Jessica L. Funnell, Derek W. Nelson, Manoj K. Gottipati, Ryan J. Gilbert
Electrospun Fiber Scaffolds For Engineering Glial Cell Behavior To Promote Neural Regeneration, Devan L. Puhl, Jessica L. Funnell, Derek W. Nelson, Manoj K. Gottipati, Ryan J. Gilbert
Chemical and Biochemical Engineering Faculty Research & Creative Works
Electrospinning is a fabrication technique used to produce nano-or micro-diameter fibers to generate biocompatible, biodegradable scaffolds for tissue engineering applications. Electro spun fiber scaffolds are advantageous for neural regeneration because they mimic the structure of the nervous system extracellular matrix and provide contact guidance for regenerating axons. Glia are non-neuronal regulatory cells that maintain homeostasis in the healthy nervous system and regulate regeneration in the injured nervous system. Electro spun fiber scaffolds offer a wide range of characteristics, such as fiber alignment, diameter, surface nano topography, and surface chemistry that can be engineered to achieve a desired glial cell response …
Aldosterone Up-Regulates Voltage-Gated Potassium Currents And Nkcc1 Protein Membrane Fractions, Parveen Bazard, Bo Ding, Harish K. Chittam, Xiaoxia Zhu, Thomas A. Parks, Thomas E. Taylor-Clark, Venkat R. Bhethanabotla, Robert D. Frisina, Joseph P. Walton
Aldosterone Up-Regulates Voltage-Gated Potassium Currents And Nkcc1 Protein Membrane Fractions, Parveen Bazard, Bo Ding, Harish K. Chittam, Xiaoxia Zhu, Thomas A. Parks, Thomas E. Taylor-Clark, Venkat R. Bhethanabotla, Robert D. Frisina, Joseph P. Walton
Chemical and Biochemical Engineering Faculty Research & Creative Works
Na+–K+–2Cl− Cotransporter (NKCC1) is a protein that aids in the active transport of sodium, potassium, and chloride ions across cell membranes. It has been shown that long-term systemic treatment with aldosterone (ALD) can enhance NKCC1 protein expression and activity in the aging cochlea resulting in improved hearing. In the present work, we used a cell line with confirmed NKCC1 expression to demonstrate that in vitro application of ALD increased outward voltage-gated potassium currents significantly, and simultaneously upregulated whole lysate and membrane portion NKCC1 protein expression. These ALD-induced changes were blocked by applying the mineralocorticoid receptor antagonist eplerenone. However, application of …
Calcium Sulfate-Containing Glass Polyalkenoate Cement For Revision Total Knee Arthroplasty Fixation, Leyla Hasandoost, Adel Alhalawani, Omar Rodriguez, Alireza Rahimnejad Yazdi, Paul Zalzal, Emil H. Schemitsch, Stephen D. Waldman, Marcello Papini, Mark R. Towler
Calcium Sulfate-Containing Glass Polyalkenoate Cement For Revision Total Knee Arthroplasty Fixation, Leyla Hasandoost, Adel Alhalawani, Omar Rodriguez, Alireza Rahimnejad Yazdi, Paul Zalzal, Emil H. Schemitsch, Stephen D. Waldman, Marcello Papini, Mark R. Towler
Chemical and Biochemical Engineering Faculty Research & Creative Works
Poly (methyl methacrylate) (PMMA) bone cement is used as a minor void filler in revision total knee arthroplasty (rTKA). The application of PMMA is indicated only for peripheral bone defects with less than 5 mm depth and that cover less than 50% of the bone surface. Treating bone defects with PMMA results in complications as a result of volumetric shrinkage, bone necrosis, and aseptic loosening. These concerns have driven the development of alternative bone cements. We report here on novel modified glass polyalkenoate cements (mGPCs) containing 1, 5 and 15 wt% calcium sulfate (CaSO4) and how the modified …
Preparation And Analysis Of Cement Bricks Based On Rice Straw, Hend Ahmed, Ibrahim M. Ibrahim, M. A. Radwan, M. A. Sadek, Hany A. Elazab
Preparation And Analysis Of Cement Bricks Based On Rice Straw, Hend Ahmed, Ibrahim M. Ibrahim, M. A. Radwan, M. A. Sadek, Hany A. Elazab
Chemical and Biochemical Engineering Faculty Research & Creative Works
In Egypt, rice straw is burnt as an easy and the cheap method to get rid of it leads to making a giant black cloud covers Cairo and southern delta governorates. Main purpose of this research is to produce green brick of cement and in-expensive agriculture waste (rice straw) with law price and good characteristics of thermal insulation and acoustic resistance. Different samples of cement brick based on rice straw of many percentages were prepared. First, select best mixture of concrete brick before adding rice straw after preparing and leave for curing time. Then, rice straw is added with various …
Hybrid Electro-Plasmonic Neural Stimulation With Visible-Light-Sensitive Gold Nanoparticles, Ratka Damnjanovic, Parveen Bazard, Robert D. Frisina, Venkat R. Bhethanabotla
Hybrid Electro-Plasmonic Neural Stimulation With Visible-Light-Sensitive Gold Nanoparticles, Ratka Damnjanovic, Parveen Bazard, Robert D. Frisina, Venkat R. Bhethanabotla
Chemical and Biochemical Engineering Faculty Research & Creative Works
Biomedical prosthetics utilizing electrical stimulation have limited, effective spatial resolution due to spread of electrical currents to surrounding tissue, causing nonselective stimulation. So, precise spatial resolution is not possible for traditional neural prosthetic devices, such as cochlear implants. More recently, alternative methods utilize optical stimulation, mainly infrared, sometimes paired with nanotechnology for stimulating action potentials. Infrared stimulation has its own drawbacks, as it may cause collateral heating of surrounding tissue. In previous work, we employed a plasmonic method for stimulation of an electrically excitable neuroblastoma cell line, which had limited success. Here, we report the development of a hybrid electro-plasmonic …
Nanoparticle Catalyzed Hydrodesulfurization Of Diesel Fuel In A Trickle Bed Reactor: Experimental And Optimization Study, Saba A. Gheni, Saad A. Awad, Safaa M. R. Ahmed, Ghassan Abdullah, Muthanna H. Al-Dahhan
Nanoparticle Catalyzed Hydrodesulfurization Of Diesel Fuel In A Trickle Bed Reactor: Experimental And Optimization Study, Saba A. Gheni, Saad A. Awad, Safaa M. R. Ahmed, Ghassan Abdullah, Muthanna H. Al-Dahhan
Chemical and Biochemical Engineering Faculty Research & Creative Works
This work focuses on the preparation, simulation, and optimization of the hydrodesulfurization (HDS) of dibenzothiophene (DBT) using a nanocatalyst. A homemade nanocatalyst (3 percent Co, 10 percent Mo/γ-Al2O3 nanoparticles) was used in a trickle bed reactor (TBR). The HDS kinetic model was estimated based on experimental observations over ranges of operating conditions to evaluate kinetic parameters of the HDS process and apply the key parameters. Based on these parameters, the performance of the TBR catalyzed by the nanocatalyst was evaluated and scaled up to a commercial scale. Also, the selectivity of HDS reactions was also modeled to …
Mathematical Modeling And Pointwise Validation Of A Spouted Bed Using An Enhanced Bed Elasticity Approach, Sebastián Uribe, Binbin Qi, Omar Farid, Muthanna H. Al-Dahhan
Mathematical Modeling And Pointwise Validation Of A Spouted Bed Using An Enhanced Bed Elasticity Approach, Sebastián Uribe, Binbin Qi, Omar Farid, Muthanna H. Al-Dahhan
Chemical and Biochemical Engineering Faculty Research & Creative Works
With a Euler-Euler (E2P) approach, a mathematical model for predicting the pointwise hydrodynamic behavior of a spouted bed was implemented though computational fluid dynamics (CFD) techniques. The model considered a bed elasticity approach in order to reduce the number of required sub-models to provide closure for the solids stress strain-tensor. However, no modulus of elasticity sub-model for a bed elasticity approach has been developed for spouted beds, and thus, large deviations in the predictions are obtained with common sub-models reported in literature. To overcome such a limitation, a new modulus of elasticity based on a sensitivity analysis was developed and …
Drug-Loaded Chitosan Film Prepared Via Facile Solution Casting And Air-Drying Of Plain Water-Based Chitosan Solution For Ocular Drug Delivery, Boxuan Li, Juan Wang, Qin Gui, Hu Yang
Drug-Loaded Chitosan Film Prepared Via Facile Solution Casting And Air-Drying Of Plain Water-Based Chitosan Solution For Ocular Drug Delivery, Boxuan Li, Juan Wang, Qin Gui, Hu Yang
Chemical and Biochemical Engineering Faculty Research & Creative Works
Chitosan is a nature-based polymer with low toxicity, excellent biocompatibility and biodegradability. However, the intractable solubility of chitosan in water and most conventional solvents hampers its biomedical applications. Following the dissolution method for dissolving chitosan in plain water developed by us, chitosan was dissolved in ionic liquid followed by overnight freezing at −20 °C and subsequent solvent exchange with plain water at room temperature. In this study, we fabricated a drug-carrying chitosan film via solution casting and air-drying by using the plain water-based chitosan solution. Specifically, brimonidine tartrate (BT), an antiglaucoma drug, was dissolved in the plain-water based solution and …
Aligned Fingolimod-Releasing Electrospun Fibers Increase Dorsal Root Ganglia Neurite Extension And Decrease Schwann Cell Expression Of Promyelinating Factors, Devan L. Puhl, Jessica L. Funnell, Anthony R. D'Amato, Jonathan Bao, Dmitri V. Zagorevski, Yelena Pressman, Daniel Morone, Agnes E. Haggerty, Martin Oudega, Ryan J. Gilbert
Aligned Fingolimod-Releasing Electrospun Fibers Increase Dorsal Root Ganglia Neurite Extension And Decrease Schwann Cell Expression Of Promyelinating Factors, Devan L. Puhl, Jessica L. Funnell, Anthony R. D'Amato, Jonathan Bao, Dmitri V. Zagorevski, Yelena Pressman, Daniel Morone, Agnes E. Haggerty, Martin Oudega, Ryan J. Gilbert
Chemical and Biochemical Engineering Faculty Research & Creative Works
Researchers are investigating the use of biomaterials with aligned guidance cues, like those provided by aligned electro spun fibers, to facilitate axonal growth across critical-length peripheral nerve defects. To enhance the regenerative outcomes further, these aligned fibers can be designed to provide local, sustained release of therapeutics. The drug fingolimod improved peripheral nerve regeneration in preclinical rodent models by stimulating a pro-regenerative Schwann cell phenotype and axonal growth. However, the systemic delivery of fingolimod for nerve repair can lead to adverse effects, so it is necessary to develop a means of providing sustained delivery of fingolimod local to the injury. …
The Kinetic Study Of Dpt Using Mathematica As An Efficient Optimization Tool, M. H. El Dewaik, Mamdouh Gadalla, M. A. Radwan, M. A. Sadek, Hany A. Elazab
The Kinetic Study Of Dpt Using Mathematica As An Efficient Optimization Tool, M. H. El Dewaik, Mamdouh Gadalla, M. A. Radwan, M. A. Sadek, Hany A. Elazab
Chemical and Biochemical Engineering Faculty Research & Creative Works
Mathematica is a powerful program for computing both numeric and algebraic calculations as well as graphing two- and three-dimensional curves and surfaces. It is used increasingly in many fields of science now such as physics, engineering, chemistry and even biology because of the fast interaction of mathematics with almost the fields of science nowadays. Synthesis of Cyclotetramethylene Tetramine through the action of nitrating mixture formed of ammonium nitrate and fuming nitric acid on hexamine in presence of acetic acid, acetic anhydride and p-formaldehyde has been proven. The pathway is relatively long and Hexamine Dinitrate and Dinitro Pentamethylene Tetramine (DPT) are …
A Review Of The Latest Insights Into The Mechanism Of Action Of Strontium In Bone, Daniella Marx, Alireza Rahimnejad Yazdi, Marcello Papini, Mark R. Towler
A Review Of The Latest Insights Into The Mechanism Of Action Of Strontium In Bone, Daniella Marx, Alireza Rahimnejad Yazdi, Marcello Papini, Mark R. Towler
Chemical and Biochemical Engineering Faculty Research & Creative Works
Interest in strontium (Sr) has persisted over the last three decades due to its unique mechanism of action: it simultaneously promotes osteoblast function and inhibits osteoclast function. While this mechanism of action is strongly supported by in vitro studies and small animal trials, recent large-scale clinical trials have demonstrated that orally administered strontium ranelate (SrRan) may have no anabolic effect on bone formation in humans. Yet, there is a strong correlation between Sr accumulation in bone and reduced fracture risk in post-menopausal women, suggesting Sr acts via a purely physiochemical mechanism to enhance bone strength. Conversely, the local administration of …
The Role Of Poly(Methyl Methacrylate) In Management Of Bone Loss And Infection In Revision Total Knee Arthroplasty: A Review, Leyla Hasandoost, Omar Rodriguez, Adel Alhalawani, Paul Zalzal, Emil H. Schemitsch, Stephen D. Waldman, Marcello Papini, Mark R. Towler
The Role Of Poly(Methyl Methacrylate) In Management Of Bone Loss And Infection In Revision Total Knee Arthroplasty: A Review, Leyla Hasandoost, Omar Rodriguez, Adel Alhalawani, Paul Zalzal, Emil H. Schemitsch, Stephen D. Waldman, Marcello Papini, Mark R. Towler
Chemical and Biochemical Engineering Faculty Research & Creative Works
Poly (methyl methacrylate) (PMMA) is widely used in joint arthroplasty to secure an implant to the host bone. Complications including fracture, bone loss and infection might cause failure of total knee arthroplasty (TKA), resulting in the need for revision total knee arthroplasty (rTKA). The goals of this paper are: (1) to identify the most common complications, outside of sepsis, arising from the application of PMMA following rTKA, (2) to discuss the current applications and drawbacks of employing PMMA in managing bone loss, (3) to review the role of PMMA in addressing bone infection following complications in rTKA. Papers published between …