Chemical Engineering Commons^™

Using Capillary Electrophoresis To Detect Amyloid Protein Aggregation, Jennifer Kurtz

Chemical Engineering Undergraduate Honors Theses

Alzheimer’s disease (AD) is the leading cause of dementia accounting for ½ to ¾ of all cases. AD is characterized by a progressive loss of cognitive function over a span of 10 years, ultimately ending in death. The main possible cause of AD being researched is the formation of soluble, oligomer amyloids. Amyloids are proteins that misfold and aggregate in the brain causing potent neurotoxic effects on neurons in the brain. Microchip electrophoresis and capillary electrophoresis are two potential methods of determining the level of amyloid aggregation. In order to detect at physiological concentrations, covalent dyes must be used to …

Photocatalytic Reactor Using Tio2 Thin Film On Quartz Tubes, Ram Mahipal Kouda

Graduate Theses and Dissertations

Photocatalysis process, as an environmental application is an advanced oxidation process with tremendous potential in the near future. Previously many researchers, have conducted photocatalysis in different reactor configuration using TiO2 slurry and thin film, using a UV light source, the constraints for these reactors are the need for the removal of TiO2 particles at the outlet stream in a slurry reactor and poor environment for the efficient use of TiO2 film using UV light, as the UV light penetration depth in water is about an inch.

Taking all this into consideration, we propose a design for reactor with efficient contact …

Visual, Spectrophotometric, And Colorimetric Measurement Of Red Wine And Wine Blends, Zachary Fricke

Chemical Engineering Undergraduate Honors Theses

Partially due to prevalence and popularity around the world, much research has been done in the field of enology and wine analysis. The visual aspect of wine is one of the key features of wine. This research focused on how blending and storage affected the color and composition of wine. Visual, sensory, color, and composition data were collected. Three primary red wine varietals (Cabernet Sauvignon, Merlot, and Zinfandel) and seven blends were analyzed for color, acidity, polymeric color, and optical density. The ten wine treatments were composed based on a mixture design model. The color and composition results were compared …

Clean Energy Water Disinfection For Small Rural Remote Communities, Nathan Bearden

Chemical Engineering Undergraduate Honors Theses

The University of Arkansas competed in the 2011 Waste-Management Education and Research Consortium (WERC) competition. The U of A team participated in Task 7, which was titled “Clean Energy Water Disinfection for Small, Remote Rural Communities”. The task looks for a solution to a continuing problem throughout the world: disinfecting water. The task’s problem statement was to develop and a standalone disinfection system that could be used for a small community. It will need at least 3000 gallons of water per day. The solution must address only bacterial disinfection and must be powered by a non-fossil based energy source. Other …

Proteome Based Development Of Novel Affinity Tail For Immobilized Metal Affinity Chromatography And Hydrophobic Interaction Chromatography, Neha Tiwari

Graduate Theses and Dissertations

At industrial scale, reducing the step in purification and recovery is desired; this not only decreases the cost but also increases the yield. Hydrophobic Interaction Chromatography (HIC) and Immobilized Metal Affinity Chromatography (IMAC) both are not harsh on biological structure or activity of proteins; also both the techniques are economical and therefore a suitable choice at industrial level. This dissertation comprises of three parts. Purpose for the Part I was to identify and characterize Escherichia coli proteins which display affinity towards both IMAC and Hydrophobic Interaction Chromatography (HIC). Co (II) IMAC was chosen as the primary capture step, followed by …

Degradation Of Polystyrene Foam Under Radiant Heat Flux, James Butler

Graduate Theses and Dissertations

As the demand for liquefied natural gas has increased, safety concerns about the performance of transport vessels under fire conditions have been raised. Current codes for the sizing of the pressure relief systems require that the vessels are able to withstand an emmissive heat flux of 108kW/m2 and do not take into account the effects of insulation loss due to thermal decomposition of the insulation materials. To address this possible oversight in the current code models were presented to a working group organized by the Society of International Gas Tanker and Terminal Operators Ltd. focusing on the decomposition rate of …

Integration Of Ce-Sscp In Genetic Analysis: Fabrication And Optimization Of The Polymer Matrix, Hannah Lintag

Chemical Engineering Undergraduate Honors Theses

Genetic analysis has become an essential aspect in the field of biological research. Genetic material contains an abundance of information that can be harnessed, from the pathological study of diseases to the identification of algal species used for alternative fuel. The detection of genetic species and/or their mutated counterparts is an approach that still warrants improvement, however. Capillary electrophoresis-single strand conformation polymorphism (CE-SSCP) offers a rapid and highly-reproducible means to detect alterations in genetic material. In this project, its implementation in the field of genetic studies as a way to detect mutations in hereditary diseases and identifying species via genetic …

Process And Automation Design For The Construction Of A Fully Automated Biofuel Production Unit, Kylan Rakestraw

Chemical Engineering Undergraduate Honors Theses

Phase I investigated a method for producing butanol from algae using a novel automated hydrolysis, fermentation, and separation process. The Phase I research team sought to experimentally optimize individual steps and parameters of the process, design and build an automated unit to produce fuel-grade butanol from algae in a batch process, evaluate the sustainability and large scale economics of the process, and design an outreach program encouraging energy and environmental awareness centered around K-12 students. The team used macroalgae samples obtained through the generosity of the City of New York from Jamaica Bay to test the equipment and viability of …

Biodiesel Production From Waste Algae Through Supercritical Methanol And Solid Catalysts, Alexander Lopez

Chemical Engineering Undergraduate Honors Theses

The need for alternate fuels continues to rise as fossil fuel reserves decline, and the effects of harmful fuel emissions on the environment begin to take its toll. One alternate fuel that has great potential is biodiesel. Biodiesel is a non-petroleum based fuel composed of alkyl esters from feedstocks. Using biodiesel as an alternate fuel source has a variety of advantages over traditional petroleum diesel, including producing no SOx emissions and low COx emissions. Another important advantage of biodiesel is that it can be produced from a wide variety of feedstocks. Biodiesel processes using waste cooking oil, animal fats, and …

Algae To Butanol: The Design, Construction, And Implementation Of An Automated Sugar-To-Fuel Process, Elizabeth Bevan

Chemical Engineering Undergraduate Honors Theses

Phase I investigated a method for producing butanol from algae using a novel automated hydrolysis, fermentation, and separation process. The Phase I research team sought to experimentally optimize individual steps and parameters of the process, design and build an automated unit to produce fuel-grade butanol from algae in a batch process, evaluate the sustainability and large scale economics of the process, and design an outreach program encouraging energy and environmental awareness centered around K-12 students. The team used macroalgae samples obtained through the generosity of the City of New York from Jamaica Bay to test the equipment and viability of …

Cost Efficient Method Of Pumping Water For Small, Remote Rural Communities, James Hudson

Chemical Engineering Undergraduate Honors Theses

Many technologies are used for water disinfection. Chlorine, iodine, and ozone are some chemical methods of water disinfection. Filtration, including microfiltration, ultrafiltration, and reverse osmosis, is used to remove bacteria. In addition to chemical and filtration technologies, one can disinfect water using UV irradiation, ultrasonic treatment, electrolysis, solar disinfection, and slow sand filtration.
Currently, there are few solutions being employed in third world settings for communities. The current solutions are either for one household or are part of an existing infrastructure and therefore are not portable. Slow sand filtration is used successfully to provide potable water for individual households. Tablet …

Extraction Of Butanol By Continuous Pervaporation Of A Two-Stage Fermentation, Kelly Meek

Chemical Engineering Undergraduate Honors Theses

Within this research a fermentation broth is used that has been developed first from the continuous fermentation of algal sugars to organic acids with Clostridium tyrobutyricum, followed by the continuous fermentation of the organic acids to butanol using Clostridium saccharoperbutylacetonium. The two-stage fermentation has the potential to increase the butanol selectivity from 60% by weight with the traditional ABE process to as high as 100% with the 2-stage process.

Conversion Of Algal Sugars To Butanol In A Novel Automated Process, Jill Ivey

Chemical Engineering Undergraduate Honors Theses

Phase I investigated a method for producing butanol from algae using a novel automated hydrolysis, fermentation, and separation process. The Phase I research team sought to experimentally optimize individual steps and parameters of the process, design and build an automated unit to produce fuel-grade butanol from algae in a batch process, evaluate the sustainability and large scale economics of the process, and design an outreach program encouraging energy and environmental awareness centered around K-12 students. The team used macroalgae samples obtained through the generosity of the City of New York from Jamaica Bay to test the equipment and viability of …

Clean Energy Water Disinfection International Environmental Education Design Contest, Howard Heffington

Chemical Engineering Undergraduate Honors Theses

Many technologies are used for water disinfection. Chlorine, iodine, and ozone are some chemical methods of water disinfection. Filtration, including microfiltration, ultrafiltration, and reverse osmosis, is used to remove bacteria. In addition to chemical and filtration technologies, one can disinfect water using UV irradiation, ultrasonic treatment, electrolysis, solar disinfection, and slow sand filtration.
Currently, there are few solutions being employed in third world settings for communities. The current solutions are either for one household or are part of an existing infrastructure and therefore are not portable. Slow sand filtration is used successfully to provide potable water for individual households. Tablet …

Water Purification For Rural Communities Using Ultraviolet Light And Bleach Systems, Ryan Lee

Chemical Engineering Undergraduate Honors Theses

Many technologies are used for water disinfection. Chlorine, iodine, and ozone are some chemical methods of water disinfection. Filtration, including microfiltration, ultrafiltration, and reverse osmosis, is used to remove bacteria. In addition to chemical and filtration technologies, one can disinfect water using UV irradiation, ultrasonic treatment, electrolysis, solar disinfection, and slow sand filtration.
Currently, there are few solutions being employed in third world settings for communities. The current solutions are either for one household or are part of an existing infrastructure and therefore are not portable. Slow sand filtration is used successfully to provide potable water for individual households. Tablet …

L'Oreal Waste Minimization, Caitlin Burns, Joe Baugh, Allen Busick, Ryan Black, Emily Evans, Matthew Margis

Chemical Engineering Undergraduate Honors Theses

The purpose of this design project is to reduce the amount of waste being generated at L’Oreal’s North Little Rock manufacturing facility. To accomplish this, the design team visited the North Little Rock manufacturing facility to examine the areas producing the most waste. After gaining a detailed understanding of these areas, the UP1 production line was identified as one of the largest opportunities for waste reduction in the L’Oreal manufacturing facility. In the UP1 processing area, mascara is mixed in large mixing tanks and then pumped in to barrels to be packaged. The 2,000 liter and 1,000 liter Olsa tanks …

Algae To Butanol: Our Contribution To People, Prosperity, And Planet, Ethan Carter

Chemical Engineering Undergraduate Honors Theses

Phase I investigated a method for producing butanol from algae using a novel automated hydrolysis, fermentation, and separation process. The Phase I research team sought to experimentally optimize individual steps and parameters of the process, design and build an automated unit to produce fuel-grade butanol from algae in a batch process, evaluate the sustainability and large scale economics of the process, and design an outreach program encouraging energy and environmental awareness centered around K-12 students. The team used macroalgae samples obtained through the generosity of the City of New York from Jamaica Bay to test the equipment and viability of …

Design And Construction Of A Novel Automated Unit For Conversion Of Algae To Butanol, Hiroko Nakao

Chemical Engineering Undergraduate Honors Theses

Phase I investigated a method for producing butanol from algae using a novel automated hydrolysis, fermentation, and separation process. The Phase I research team sought to experimentally optimize individual steps and parameters of the process, design and build an automated unit to produce fuel-grade butanol from algae in a batch process, evaluate the sustainability and large scale economics of the process, and design an outreach program encouraging energy and environmental awareness centered around K-12 students. The team used macroalgae samples obtained through the generosity of the City of New York from Jamaica Bay to test the equipment and viability of …

Synthesis And Analysis Of The Antimicrobial Peptoid N-Lfb6, Allen Busick

Chemical Engineering Undergraduate Honors Theses

The increasing presence of drug resistant bacteria has led to research of new methods to combat bacteria. A part of the natural peptide Lactoferricin, LfB6 (RRWQWR-NH2), has been shown to be effective against a variety of gram positive and gram negative bacteria. However, there are several problems associated with peptides. Peptides can quickly degrade in the body which causes larger doses to be effective. Large doses of some peptides are cytotoxic to the host. Peptoids are a class of compounds that can potentially mimic the function of peptides and circumvent the problems associated with them. The backbone of peptoids is …

Innovation And Development Of Biofuel Technologies, Nicole Lorenz

Chemical Engineering Undergraduate Honors Theses

The need for viable alternatives to gasoline has lead researchers to explore various options for renewable energy resources. This research study focuses on two major options for renewable energy. The first is biodiesel, which is a fuel that can be made from vegetable oils or animal fats. In this study, biodiesel was made from tall oil, a paper byproduct. A novel reaction method was used, employing high temperature methanol rather than acid or base catalysis. The second option that was investigated is butanol, which is an alcohol with advantages over ethanol. First, a two-step fermentation was examined to improve the …

Non-Natural Protein Mimetics For The Treatment Of Alzheimer's Disease, Jennifer Herrera, Amanada Compean, Jasmine Brown, Melissa Moss, Shannon Servoss

Chemical Engineering Undergraduate Honors Theses

Alzheimer's disease (AD) is a slow degenerative disease that causes memory loss and eventually leads to death. AD is caused by the aggregation of the amyloid-beta protein, found on the outside of brain cells; once the amyloid-beta protein begins to aggregate it forms plaques on the extracellular part of the neural cells. To date there is no AD medication commercially available that breaks up the amyloid-beta aggregates. Current research has found that certain molecules bind to the amyloid-beta protein and prevent aggregation. The purpose of this research project is to engineer a peptoid-based molecule to stop the aggregation of the …

A Review Of The Benefits And Applications Of The Thorium Fuel Cycle, Vincent Hall

Chemical Engineering Undergraduate Honors Theses

This paper aims to inform the reader of the benefits that can be achieved by using thorium as a fuel for nuclear power. Stages of the thorium cycle are directly compared against the current uranium based nuclear fuel cycle. These include mining, milling, fuel fabrication, use of various reactor designs, reprocessing, and disposal. Thorium power promises several key advantages over traditional nuclear power methods, namely a dramatic decrease in long lived radioactive waste, increased fuel efficiency, greater chemical stability during disposal, and higher adaptability for differing reactor designs across a wider range of the thermal neutron spectrum. Obstacles that face …

Production Of Biobutanol From Biomass Using Novel Membrane Reactor, Natalie Thibodeaux

Chemical Engineering Undergraduate Honors Theses

Producing biobutanol from a waste product on a large scale is a novel idea. Because of this, there is very little research available in this area. Previous fermentation research has primarily focused on the production of ethanol or biobutanol using cellulosic or agricultural feed stocks. The Phase I research team, Team R azorbacks E ngineering FU el S olutions for E veryone (Team REFUSE), sought to design a fermentation process that would produce butanol from food waste. Team REFUSE cultivated a partnership with Chartwells, the campus food service provider for the University of Arkansas, for the acquisition of food waste. …

Production Of Biobutanol From Biomass Using Novel Membrane Reactor: A P3 Experience, Ashley Haub

Chemical Engineering Undergraduate Honors Theses

Producing biobutanol from a waste product on a large scale is a novel idea. Because of this, there is very little research available in this area. Previous fermentation research has primarily focused on the production of ethanol or biobutanol using cellulosic or agricultural feed stocks. The Phase I research team, Team R azorbacks E ngineering FU el S olutions for E veryone (Team REFUSE), sought to design a fermentation process that would produce butanol from food waste. Team REFUSE cultivated a partnership with Chartwells, the campus food service provider for the University of Arkansas, for the acquisition of food waste. …

A Robust Process For Biodiesel Production Using Supercritical Methanol, Meagan Magie

Chemical Engineering Undergraduate Honors Theses

The overarching purpose of Phase I was to test, at the bench scale, a continuous supercritical methanol reactor, and to determine the feasibility of implementing the technology at full scale. Specific objectives in reaching this purpose included:
Objective 1: Choose a viable feedstock
Objective 2: Perform experiments for oil extraction
Objective 3: Design, build and operate a continuous supercritical methanol reactor
Objective 4: Design and simulate full scale biodiesel facility
Objective 4a: Perform life-cycle and economic analysis on full scale design
Objective 5: Prepare a Phase II P3 project to demonstrate the entire biodiesel process
Project Scope: The students performed …

A Robust Process For Biodiesel Production Using Supercritical Methanol, Travis Roberts

Chemical Engineering Undergraduate Honors Theses

The overarching purpose of Phase I was to test, at the bench scale, a continuous supercritical methanol reactor, and to determine the feasibility of implementing the technology at full scale. Specific objectives in reaching this purpose included:
Objective 1: Choose a viable feedstock
Objective 2: Perform experiments for oil extraction
Objective 3: Design, build and operate a continuous supercritical methanol reactor
Objective 4: Design and simulate full scale biodiesel facility
Objective 4a: Perform life-cycle and economic analysis on full scale design
Objective 5: Prepare a Phase II P3 project to demonstrate the entire biodiesel process
Project Scope: The students performed …

A Robust Process For Biodiesel Production Using Supercritical Methanol, Thomas Kasprowicz

Chemical Engineering Undergraduate Honors Theses

The overarching purpose of Phase I was to test, at the bench scale, a continuous supercritical methanol reactor, and to determine the feasibility of implementing the technology at full scale. Specific objectives in reaching this purpose included:
Objective 1: Choose a viable feedstock
Objective 2: Perform experiments for oil extraction
Objective 3: Design, build and operate a continuous supercritical methanol reactor
Objective 4: Design and simulate full scale biodiesel facility
Objective 4a: Perform life-cycle and economic analysis on full scale design
Objective 5: Prepare a Phase II P3 project to demonstrate the entire biodiesel process
Project Scope: The students performed …

Production Of Biobutanol From Biomass Using Novel Membrane Reactor: A P3 Experience, Ellen Draehn

Chemical Engineering Undergraduate Honors Theses

Producing biobutanol from a waste product on a large scale is a novel idea. Because of this, there is very little research available in this area. Previous fermentation research has primarily focused on the production of ethanol or biobutanol using cellulosic or agricultural feed stocks. The Phase I research team, Team R azorbacks E ngineering FU el S olutions for E veryone (Team REFUSE), sought to design a fermentation process that would produce butanol from food waste. Team REFUSE cultivated a partnership with Chartwells, the campus food service provider for the University of Arkansas, for the acquisition of food waste. …

Proximate Characterization And Lycopene Determination In Bitter Melon Seed Aril, Luis Raul Jimenez Interiano

Chemical Engineering Undergraduate Honors Theses

Bitter melon aril is the mucilage covering the fruit's seeds which could contain beneficial dietary ingredients. The bright red color of bitter melon aril suggests that it could contain lycopene. The purpose of this study was to determine the proximate composition of bitter melon aril and to explore this material as a potential rich source of lycopene that has health benefits. Bitter melon aril from Sri Lanka, harvested in Arkansas, USA in 2005, 2006, and 2007 was analyzed. An investigation to develop an extraction method for lycopene from bitter melon was performed using liquid-liquid and a polar liquid extraction. The …

Understanding The Effects Of Hydrophobicity For The Detection Of Methylated Dna By Microchannel Electrophoresis, Micah Fritsche

Chemical Engineering Undergraduate Honors Theses

DNA methylation is an epigenetic mechanism used for long - term silencing of gene expression. This silencing of gene expression can be involved in the down regulation of genes involved in apoptosis, which is a process of regulated cell death, and this inability to break down cells can ultimately lead to tumor formation in cancer. Methylation of DNA follows a certain pattern through developmental stages of an individual, and this pattern is normally maintained throughout that individual's life. However, in the DNA of older individuals, this methylation is commonly seen to be altered. This altered pattern of methylation can be …