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Full-Text Articles in Systems and Integrative Engineering

High-Throughput Nanoliter Dispensing Device For Biological Applications, Cole Reynolds, Euiwon Bae Dr., J Paul Robinson Dr. Aug 2018

High-Throughput Nanoliter Dispensing Device For Biological Applications, Cole Reynolds, Euiwon Bae Dr., J Paul Robinson Dr.

The Summer Undergraduate Research Fellowship (SURF) Symposium

Pathogen identification is a field that can contribute largely to the prevention of the spreading of illness and disease. In the past, pathogen identification has been a long and arduous process due to the time-consuming processes and steps that requires technician’s time and effort. With new technologies emerging however, screening of bacteria colonies can be done in a quick and high-throughput way. The problem is that using the current methods, bacteria cannot be transferred to petri dishes fast enough to keep up with the new screening methods. The current study focuses on exploring different methods to create an ergonomic device …


Mechanical Reliability Of Implantable Polyimide-Based Magnetic Microactuators For Biofouling Removal, Christian G. Figueroa-Espada, Qi Yang, Hyowon Lee Aug 2016

Mechanical Reliability Of Implantable Polyimide-Based Magnetic Microactuators For Biofouling Removal, Christian G. Figueroa-Espada, Qi Yang, Hyowon Lee

The Summer Undergraduate Research Fellowship (SURF) Symposium

Hydrocephalus is a neurological disorder that typically requires a long-term implantation of a shunt system to manage its symptoms. These shunt systems are notorious for their extremely high failure rate. More than 40% of all implanted shunt systems fail within the first year of implantation. On average, 85% of all hydrocephalus patients with shunt systems undergo at least two shunt-revision surgeries within 10 years of implantation. A large portion of this high failure rate can be attributed to biofouling-related obstructions and infections. Previously, we developed flexible polyimide-based magnetic microactuators to remove obstructions formed on hydrocephalus shunts. To test the long-term …


An Implantable Device To Regulate Urination Through Deep Brain Stimulation, Jesse E. Bucksot, Muhammad A. Arafat, Pedro Irazoqui Aug 2015

An Implantable Device To Regulate Urination Through Deep Brain Stimulation, Jesse E. Bucksot, Muhammad A. Arafat, Pedro Irazoqui

The Summer Undergraduate Research Fellowship (SURF) Symposium

Urinary Incontinence (UI) is a disease in which patients lose control of their bladder. It is particularly common in elderly women having a prevalence of as much as 30% to 50% [1]. Many of these patients are left without successful treatment. A recent study has shown a new option for treatment that consists of deep brain stimulation (DBS) at a site known as the periaqueductal gray (PAG) [2, 3]. To test the effectiveness of this treatment, chronic stimulation of the PAG should be used in animals to see if it can reliably prevent micturition in the long term. A device …