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Other Biomedical Engineering and Bioengineering Commons™
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- Feeding tubes (2)
- Medical balloons (2)
- NG tube (2)
- Nasogastric feeding tube (2)
- Tube dislodgement (2)
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- 3D Print (1)
- Actin (1)
- Antibody-conjugated microneedle patch for early MRSA biomarker detection (1)
- Bioinformatics (1)
- Biomedical Engineering (1)
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- Crutch tip (1)
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- Design (1)
- Early infection detection device (1)
- Engineering (1)
- Gait Analysis (1)
- Helper T Cells (1)
- Helper T Cytokines (1)
- Improved stability (1)
- Kinect (1)
- Motor Protein (1)
- Multi-terrain (1)
- Myosin (1)
- New Crutch Tip (1)
- Optical Trapping (1)
Articles 1 - 9 of 9
Full-Text Articles in Other Biomedical Engineering and Bioengineering
Design And Evaluation Of Antibody-Conjugated Microneedle Patch For Early Mrsa Biomarker Detection, Kylee Marie Pop, Alexis Richie, Nicholas Jenkins, Andrew Holmes
Design And Evaluation Of Antibody-Conjugated Microneedle Patch For Early Mrsa Biomarker Detection, Kylee Marie Pop, Alexis Richie, Nicholas Jenkins, Andrew Holmes
Honors Theses
Post-operative orthopedic surgical site infections (SSIs), specifically those caused by methicillin resistant Staphylococcus aureus (MRSA), present a significant clinical challenge due to delayed detection, increased morbidity, and current rising healthcare costs. Early detection of infection remains limited due to the current methods of diagnosis, which consist of observation of the surgical site and laboratory infrastructure for conformation of infection. To combat these issues, my team and I have designed and evaluated a minimally invasive microneedle diagnostic patch that continuously monitors for the presence of MRSA-associated biomarker PBP2a in interstitial fluids around surgical site incisions. Upon antigen detection, a colorimetric response …
Redesigning Nasogastric Feeding Tubes To Prevent Dislodgement, Sydney Ruth Rester, Shelby Lynn Berry
Redesigning Nasogastric Feeding Tubes To Prevent Dislodgement, Sydney Ruth Rester, Shelby Lynn Berry
Honors Theses
Seniors at the University of Mississippi studying biomedical engineering complete a senior project that seeks to solve a problem in healthcare. Our team, composed of Sydney Rester, Shelby Berry, Andrew Ulmer, and Alex Bromley, sought to improve care associated with nasogastric feeding tubes. We identified two major problems: clogging and tube dislodgement. To address the problem of dislodgement, the team crafted a new feeding tube design with a balloon attachment. The attachment prevents a patient from pulling the feeding tube out and keeps the tube from dislodging due to normal patient movement. We further determined that our tube should be …
Redesigning Nasogastric Feeding Tubes To Prevent Dislodgement, Shelby Lynn Berry, Sydney Ruth Rester
Redesigning Nasogastric Feeding Tubes To Prevent Dislodgement, Shelby Lynn Berry, Sydney Ruth Rester
Honors Theses
Seniors at the University of Mississippi studying biomedical engineering complete a senior project that seeks to solve a problem in healthcare. Our team, composed of Sydney Rester, Shelby Berry, Andrew Ulmer, and Alex Bromley, sought to improve care associated with nasogastric feeding tubes. We identified two major problems: clogging and tube dislodgement. To address the problem of dislodgement, the team crafted a new feeding tube design with a balloon attachment. The attachment prevents a patient from pulling the feeding tube out and keeps the tube from dislodging due to normal patient movement. We further determined that our tube should be …
Investigating Myosin Ensemble Force Generation Using Optical Tweezers, Janie Watts
Investigating Myosin Ensemble Force Generation Using Optical Tweezers, Janie Watts
Honors Theses
Myosin is a motor protein that facilitates muscle contraction and movement by stepping along actin filaments using energy from ATP hydrolysis. If myosin or other motors are disrupted throughout the body, it can have many harmful effects. Hypertrophic cardiomyopathy is a disease caused by gene mutations that affect myosin heavy chains in the heart. The tissue of the heart becomes abnormally thick, which can make it more difficult to pump blood or block blood flow out of the heart. Our goal is to discern the mechanistic difference function of a healthy and diseased heart. To accomplish this, we construct model …
Th1, Th2, And Th17 Inflammatory Pathways Predict Cardiometabolic Protein Expression In Serum Of Covid-19 Patients, James Richard Michels
Th1, Th2, And Th17 Inflammatory Pathways Predict Cardiometabolic Protein Expression In Serum Of Covid-19 Patients, James Richard Michels
Honors Theses
A predominant source of complications in SARS-CoV-2 patients arises from severe systemic inflammation contributed to by Helper T-cell associated cytokines, potentially leading to tissue damage and organ failure. The high inflammatory burden of this viral infection often results in cardiovascular comorbidities. A better understanding of the interaction between the cytokine storm and cardiovascular proteins might inform medical decisions and therapeutic approaches. We hypothesized that all major helper T-cell inflammatory pathways (Helper T 1, Helper T 2 and Helper T 17) synergistically contribute to cardiometabolic pathways in serum of COVID-19 patients, and that both of these factors correlate to COVID-19 severity. …
Developing New Crutch Tip Design For Overall Increased Stability And Improved Movement On Different Terrains, Lauren Skinner
Developing New Crutch Tip Design For Overall Increased Stability And Improved Movement On Different Terrains, Lauren Skinner
Honors Theses
Crutches are a mobility assistive device that are often used in various situations, such as post- surgical rehabilitation and recovery after injury. The current crutch tip design that is used on today’s crutches are often unstable and do not provide quality movement on different terrains, such as snow, ice, mud, and wet surfaces. These problems would be solved with a new tip design that could be attached to existing crutches or manufactured with the crutch itself. The team’s solution to this problem is a crutch tip with modular parts. The tip would attach to the shaft of the crutch like …
Comparative Analysis Of Computationally Accelerated Ngs Alignment, Ada Chaeli Van Der Zijp-Tan
Comparative Analysis Of Computationally Accelerated Ngs Alignment, Ada Chaeli Van Der Zijp-Tan
Honors Theses
The Smith-Waterman algorithm is the basis of most current sequence alignment technology, which can be used to identify similarities between sequences for cancer detection and treatment because it provides researchers with potential targets for early diagnosis and personalized treatment. The growing number of DNA and RNA sequences available to analyze necessitates faster alignment processes than are possible with current iterations of the Smith-Waterman (S-W) algorithm. This project aimed to identify the most effective and efficient methods for accelerating the S-W algorithm by investigating recent advances in sequence alignment. Out of a total of 22 articles considered in this project, 17 …
Ogt Glycosylation Of Histones In T Cells May Participate In Systemic Lupus Erythematosus, Jared Luke Ridgeway
Ogt Glycosylation Of Histones In T Cells May Participate In Systemic Lupus Erythematosus, Jared Luke Ridgeway
Honors Theses
Systemic Lupus Erythematosus (SLE) is a chronic autoimmune disease that primarily affects women. The etiology is not known yet, but genetics and environmental factors trigger the disease. These epigenetic changes modify gene expression and contribute to the development of the disease. It is known that T cells from patients with lupus overexpress genes that may contribute to the onset and progression of the disease. Dr. Gorelik has shown that OGT (O-linked N-acetyl-Glucosamine Transferase), which is an X-linked gene, is overexpressed in women with SLE. OGT adds b-N-acetylglucosamine (O-GlcNAc) to serine and threonine residues of proteins. …
Implementation Of A Computer-Vision System As A Supportive Diagnostic Tool For Parkinson’S Disease, Diego Machado Reyes
Implementation Of A Computer-Vision System As A Supportive Diagnostic Tool For Parkinson’S Disease, Diego Machado Reyes
Honors Theses
Parkinson’s disease is the second most common neurodegenerative disorder, affecting nearly 1 million people in the US and it is predicted that the number will keep increasing. Parkinson’s disease is difficult to diagnose due to its similarity with other diseases that share the parkinsonian symptoms and the subjectivity of its assessment, thus increasing the probabilities of misdiagnosis. Therefore, it is relevant to develop diagnostic tools that are quantitatively based and monitoring tools to improve the patient’s quality of life. Computer-based assessment systems have shown to be successful in this field through diverse approaches that can be classified into two main …