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Other Biomedical Engineering and Bioengineering Commons™
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Articles 31 - 38 of 38
Full-Text Articles in Other Biomedical Engineering and Bioengineering
Vascular Reactivity Of Immature Arterialized Capillaries, Sara Hellstrom
Vascular Reactivity Of Immature Arterialized Capillaries, Sara Hellstrom
Biomedical Engineering
Peripheral arterial occlusive disease (PAOD) is a globally prevalent cardiovascular disease in which atherosclerotic plaques narrow arterial lumen diameters and restrict blood flow to down stream tissues. The impact of these occlusions can be mitigated by collateral vessels that connect parallel arterial branches and act as natural bypasses to maintain perfusion. Some patients with PAOD may not have robust collateral networks to accommodate ischemic tissues in the event of an occlusion and, therefore, may be more susceptible to hypoxia and tissue necrosis. In animal models that lack collateral arterioles, capillaries can arterialize and form functional collaterals; however, in the early …
Guidance System, Kayaking For The Visually Impaired, D. Ryan Kirtland, Ryan Phife, William Gardner, Amy Johnson
Guidance System, Kayaking For The Visually Impaired, D. Ryan Kirtland, Ryan Phife, William Gardner, Amy Johnson
Biomedical Engineering
Quality Life Plus is working with Team River Runner to develop an assistive guidance system for veterans who want to remain active by kayaking, after sustaining an injury that impairs vision. This system allows these veterans to complete a slalom speed race independent of a personal guide in the water. The system incorporates 3 stations that each contain a speaker connected to a microcontroller system covered by a Pelican Case on a custom made buoy. During the slalom race, a kayaker will travel from shore towards buoy #1 as it omits sound from the speaker. As the kayaker moves around …
A Microfluidic Pretreatment Isoelectric Focusing Dc-Field Assisted H-Filter For The Separation Of Charged Particles, Cameron Sean Carroll
A Microfluidic Pretreatment Isoelectric Focusing Dc-Field Assisted H-Filter For The Separation Of Charged Particles, Cameron Sean Carroll
Biomedical Engineering
Microfluidic devices are small portable diagnostic chips that allow for analysis of a biologic sample at relatively low cost. This makes them ideal for settings where a hospital is unavailable. The microfluidic pretreatment isoelectric focusing DC-field assisted H-filter is a device that allows for the separation of differently charged particles in a biologic sample. It does this by employing the concepts of diffusion, electrophoresis, and isoelectric focusing. This is perfect for isolation of a desired analyte or separation of waste from a sample in order to achieve better diagnostic results. The device was first modeled mathematically and visually using Comsol. …
Development Of A Protocol To Measure Gene Expression In The Mouse Tibia, Daniel Hoover
Development Of A Protocol To Measure Gene Expression In The Mouse Tibia, Daniel Hoover
Biomedical Engineering
Numerous molecular factors active in bone tissue direct fracture repair and remodeling which can be altered by disease conditions such as Peripheral Arterial Disease (PAD) and Osteoporosis. Methods of molecular biology are commonly applied to investigate the expression and role of these molecular factors. This project presents a robust three-step protocol for examining gene expression in the mouse tibia. The protocol begins with isolating RNA from a flash frozen tibia sample. The isolated RNA is reverse transcribed into cDNA. Finally, PCR is performed to indentify expressed genes. Establishing this protocol will allow further research into the mechanisms of bone remodeling …
Hydraulically Driven Mechanical Representation Of A Biological System, Andrea Argouarch, Michael Mceachern, Brandon Parham
Hydraulically Driven Mechanical Representation Of A Biological System, Andrea Argouarch, Michael Mceachern, Brandon Parham
Biomedical Engineering
No abstract provided.
Evaluation Of Decellularization Procedures For Porcine Arteries, Charles Clapp
Evaluation Of Decellularization Procedures For Porcine Arteries, Charles Clapp
Biomedical Engineering
Coronary artery disease has become the leading cause of death in the United States, with over 425,000 deaths in 2006. Stenting has evolved into the preferred preventative technique for myocardial infarction by opening up an occluded artery, due to its low invasiveness compared to the alternative of coronary artery bypass grafting. Bare metal stents have been improved by coating with anti-proliferative drugs to advance their effects, but even drug eluting stents still have a risk of restenosis, thrombus formation, and necessary revascularization. Continual advancement in stent design necessitates faster, effective pre-clinical evaluation techniques. Kristen Cardinal, Ph.D., developed the blood vessel …
Effect Of Size Reduction Parameters In Pharmaceutical Manufacturing Process, Brian Breneman
Effect Of Size Reduction Parameters In Pharmaceutical Manufacturing Process, Brian Breneman
Biomedical Engineering
Within pharmaceutical manufacturing, size reduction is one of the most extensively used and vital unit operations. Size reduction in tablet production is achieved primarily through milling procedures, which allows for attaining product uniformity, optimizing product solubility, and improving bioavailability. Additionally, powders with a narrow range of size distribution can obviate problems in downstream processing as pertains to blending, compression, and coating as well as improve drug performance1. The purpose this study was to characterize the effect of various size reduction parameters as a result of the pharmaceutical milling process on a lactose wet granulation formulation and chemically active …
An Inexpensive Method For Creating Paste To Be Used In Paper-Based Microfluidic Devices, Kirra Marie Sankey
An Inexpensive Method For Creating Paste To Be Used In Paper-Based Microfluidic Devices, Kirra Marie Sankey
Biomedical Engineering
Microfluidic devices are diagnostic tools that are small, portable, and inexpensive. This makes them ideally suited for resource-limited settings. To construct a 3D device, each layer of patterned paper is stacked using double-sided tape with holes corresponding to the pattern. It is necessary to have a paste to fill the holes in the tape and provide a medium for the fluid to wick through. The powder used to make the paste is very expensive and must be bought in bulk (an estimated $1121 - $1231), so it is not convenient for the Biomedical (BMED) department to use. This project was …